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VMRSAAMNIKVTLEHRTSYTFNRLVQVCPHVVRVHLAPHSRPPIEAHSLQIEPAGHFINCQQDTLGNGLT RLVLPNPMRRRSIGFGLITNLKMISPFDCYIENWAETWPATARSGPTFTYPEALAEDLKPYLRPVDEAGN RFVDNELVWAWIRNFPVPDGIRTINFINFLVAFNQAMNAEVSDIVCMEHGVPTTDFTLRTGISSCRDSAW LLVSILWQMRLTAWVVSSSATSYNCPPISRHSTSHRGLPPNSPTCTPGPKCPSPVRAKSGWTRSRGCSPT RSAYRWQPHHILRRQRRPTAQPTRAKRCWTSLTLSTQVQEDPHITLPYSDVAWHAICAIGQHGYQRLTVG GKPTVVLVNIHPNKGRKEWTMVAKSPSKRQPASDLTARLKAAWAPQGLIHFRQGQWYTGEPLPQWQITLY WRTKGQPLWTNDALLTDTWKAGPSERNKTTLEDSELAHKVLAQAADGLGLPLTQMRAAYKDTLRRLAAKV RIPSGAPVQLSDDRGPTTPDSAVNRVALLTRLEESVTLPDAYMLSLHSRDDNLSWVQATLQLHRGCIVLI EDASLAGLLLPLDSISWPRPHVSFYLDPMTFWRAWSAEPNTAAAVLENPDSAPPTAMVAEIRGEFLSIFL SPTETLKHFVSLVSGGETAAANIGCPVVIEGYGLPTDLRLKSMCVKPGQVAAAASFAAERQQLETFYAQA GMARLSTESFDDSGAHGRTGGNNHITLGDVTPLRRHPDLLVSLLTCWQRHPSRSYRFAGQFVGPISQAPQ VDEVRAFRHLVVDITGNIHHAEFCIDKLHSHDNTHGRLSLLELRGFAMPLYLQMVIVRWLLVRSLVAWFW EEPLRASVIRHGTNLHGRYLFPHFVSHDMAAIATSLREHGLAFETNWLYPFIEFRLPRLGTSVFHGVEIE LRNAIEPWTTFGEKSTVTSRGGCTYHASHTGSKAINTGSTLEAQARWSRRFEATGFIPSKITMSCIRKSK SVSPPTSTRLASSTSDASAP
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. leprae Br4923 | MLBr_02678 | - | - | 100% (1000) | hypothetical protein MLBr_02678 |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2595 | - | 1e-138 | 52.59% (540) | hypothetical protein Mb2595 |
M. gilvum PYR-GCK | Mflv_3771 | - | 0.0 | 49.36% (1009) | transglutaminase domain-containing protein |
M. tuberculosis H37Rv | Rv2566 | - | 0.0 | 54.44% (990) | hypothetical protein Rv2566 |
M. abscessus ATCC 19977 | MAB_2859c | - | 0.0 | 46.94% (980) | transglutaminase family protein |
M. marinum M | MMAR_2165 | - | 0.0 | 53.85% (986) | transglutaminase family protein |
M. avium 104 | - | - | - | - | - |
M. smegmatis MC2 155 | MSMEG_3016 | - | 0.0 | 50.10% (980) | hypothetical protein MSMEG_3016 |
M. thermoresistible (build 8) | - | - | - | - | - |
M. ulcerans Agy99 | MUL_1749 | - | 3e-97 | 50.48% (418) | transglutaminase family protein |
M. vanbaalenii PYR-1 | Mvan_2628 | - | 0.0 | 51.67% (989) | transglutaminase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_3771|M.gilvum_PYR-GCK ---------------------------MGIKVALEHRTSYTFDRLVEVHP Mvan_2628|M.vanbaalenii_PYR-1 ---------------------------MGIKVALEHRTSYTFDRLVEVYP MSMEG_3016|M.smegmatis_MC2_155 ---------------------------MGIKVALEHRTSYTFDRLVEIHP MAB_2859c|M.abscessus_ATCC_199 ---------------------------MGIKVALEHRTSYAFDRLVQVHP Mb2595|M.bovis_AF2122/97 MPLRPTQVSSTGRTRCAGRSGVISSAAMSIKVALEHRTSYTFDRLVRVYP Rv2566|M.tuberculosis_H37Rv MPLRPTQVSGTGRTRCAGRSGVISSAAMSIKVALEHRTSYTFDRLVRVYP MMAR_2165|M.marinum_M ----------------------MGSASMSIKVALEHRTSYTFDKLVQVYP MUL_1749|M.ulcerans_Agy99 ---------------------MMGSASMSIKVALEHRTSYTFDKLVQVYP MLBr_02678|M.leprae_Br4923 ---------------------MMRSAAMNIKVTLEHRTSYTFNRLVQVCP *.***:*******:*::**.: * Mflv_3771|M.gilvum_PYR-GCK HVVRLRPAPHSRTPIEAYSLQVEPADHFVNWQQDAFGNFLARLVFTTRAR Mvan_2628|M.vanbaalenii_PYR-1 HVVRLRPAPHSRTPIEAYSLQVEPADHFINWQQDAFGNFLARLVFPTRTR MSMEG_3016|M.smegmatis_MC2_155 HVVRLRPAPHCRTPIDAYSLTVEPADHFINWQQDAFGNHMARLVFPNRAR MAB_2859c|M.abscessus_ATCC_199 HEIRLRPAPHTRTPIEAYSLRIAPDDHFINWQQDAFGNFLARVVFPNRTR Mb2595|M.bovis_AF2122/97 HIVRLRPAPHSRTSIEAYSLRIEPADHFINWQQDALGNFLARLVFPNPMR Rv2566|M.tuberculosis_H37Rv HIVRLRPAPHSRTSIEAYSLRIEPADHFINWQQDALGNFLARLVFPNPMR MMAR_2165|M.marinum_M HVVRLRPAPHSRTPIEAYSLRVEPTEHFVNWQQDALGNFMARLVFPKPMQ MUL_1749|M.ulcerans_Agy99 HVVRLRPAPHSRTPIEAYSLRVEPTEHFVNWQQDALGNFMARLVFPKPMQ MLBr_02678|M.leprae_Br4923 HVVRVHLAPHSRPPIEAHSLQIEPAGHFINCQQDTLGNGLTRLVLPNPMR * :*:: *** *..*:*:** : * **:* ***::** ::*:*:.. : Mflv_3771|M.gilvum_PYR-GCK SLTITVGLIADLKVVNPFDFFIEDYAERV--------GFAYPKALAEDLK Mvan_2628|M.vanbaalenii_PYR-1 SLTVTVGLIADMKVVNPFDFFIEDYAEQV--------GFTYPESLAEDLK MSMEG_3016|M.smegmatis_MC2_155 ELTVTVGLIADLKVINPFDFFIEDYAETV--------PFEYPRALREDLK MAB_2859c|M.abscessus_ATCC_199 QLSITVGLIADLKSVNPFDFFIEEWAEHI--------GFVYPPALAADLE Mb2595|M.bovis_AF2122/97 QLRITVGLIADLKVINPFDFFIEDWAEIWPC-----AGMAYPKALADDLR Rv2566|M.tuberculosis_H37Rv QLRITVGLIADLKVINPFDFFIEDWAEIWPC-----AGMAYPKALADDLR MMAR_2165|M.marinum_M HLTITVGLIADLKVINPFDFFIEEWAETWPA-----EGLTYPKALADDLK MUL_1749|M.ulcerans_Agy99 HLTITVGLIADLKVINPFDFFIEEWAETWPA-----EGLTYPKALADDLK MLBr_02678|M.leprae_Br4923 RRSIGFGLITNLKMISPFDCYIENWAETWPATARSGPTFTYPEALAEDLK : .***:::* :.*** :**::** : ** :* **. Mflv_3771|M.gilvum_PYR-GCK PYLRPVDEDGEGTGPGDLAAAWVSNFSVATGTRTI---DFLVALNRAVNA Mvan_2628|M.vanbaalenii_PYR-1 PYLRPVDEEGPGSGPGDLVEAWVKNFTVASGTRTI---DYLVALNRAVNA MSMEG_3016|M.smegmatis_MC2_155 PYLRPVDEGAEGSGPGELCAAWVSNFTMPPGTATI---QFLVALNQAVNA MAB_2859c|M.abscessus_ATCC_199 PYLKPVDESEPGSGPGELVRAWVANFTMAPTTRII---DYLVTLNQALCS Mb2595|M.bovis_AF2122/97 PYLRPVDEDGDGSGPGELTQAWVRNFTVPDGTRTI---DFLVALNRAINA Rv2566|M.tuberculosis_H37Rv PYLRPVDEDGDGSGPGELTQAWVRNFTVPDGTRTI---DFLVALNRAINA MMAR_2165|M.marinum_M PYLRPVDETGEESGPGDLVRAWVANFSVPEGTRTI---DFLVAINHAVNA MUL_1749|M.ulcerans_Agy99 PYLRPVDETGEESGPGDLVRAWVANFSVPEGTRTI---DFLVAINHAVNA MLBr_02678|M.leprae_Br4923 PYLRPVDEAGNRFVDNELVWAWIRNFPVPDGIRTINFINFLVAFNQAMNA ***:**** .:* **: **.:. * ::**::*:*: : Mflv_3771|M.gilvum_PYR-GCK DVGYSVRMEPGVQTPDVTLRTGIGSCRDSAWLLVSILRQLGLAARFVSG- Mvan_2628|M.vanbaalenii_PYR-1 DVGYSVRMEPGVQTPDFTLRTGIGSCRDSAWLLVSILRQLGLAARFVSG- MSMEG_3016|M.smegmatis_MC2_155 DVGYSVRMEAGVQTPDHTLRTGIGSCRDSAWLLVSILRQLGFAARFVSG- MAB_2859c|M.abscessus_ATCC_199 DVGYAVRLEPGVQSPDTTLAVGIGSCRDTAWLLVSILRQKGLAARFVSG- Mb2595|M.bovis_AF2122/97 DVGYCVRMEPGVQTPDFTLRTGVGSCRDSAWLLVSILRQFGLAARFVSG- Rv2566|M.tuberculosis_H37Rv DVGYCVRMEPGVQTPDFTLRTGVGSCRDSAWLLVSILRQFGLAARFVSG- MMAR_2165|M.marinum_M DVGYSVRMEPGVQTPDFTLRTGIGSCRDSAWLLVSILRQFGLAARFVSG- MUL_1749|M.ulcerans_Agy99 DVGYSVRMEPGVQTPDFTLRTGIGSCRDSAWLLVSILRQFGLAARFVSG- MLBr_02678|M.leprae_Br4923 EVSDIVCMEHGVPTTDFTLRTGISSCRDSAWLLVSILWQMRLTAWVVSSS :*. * :* ** :.* ** .*:.****:******** * ::* .**. Mflv_3771|M.gilvum_PYR-GCK ----YLVQLTSDVEALDGPSGPAADFTDLHAWTEVYIPGAGWIGLDPTSG Mvan_2628|M.vanbaalenii_PYR-1 ----YLVQLTSDIEALDGPSGPAADFTDLHAWTEVYIPGAGWIGLDPTSG MSMEG_3016|M.smegmatis_MC2_155 ----YLVQLTSDVEALDGPSGPAADFTDLHAWTEVYIPGAGWIGLDPTSG MAB_2859c|M.abscessus_ATCC_199 ----YLVQLTSDIAEIDGPSGPVADFTDLHAWAEVYIPGAGWVGLDPTSG Mb2595|M.bovis_AF2122/97 ----YLVQLASDIEALDGPSGPAADFTDLHAWSEAYIPGAGWIGLDPTSG Rv2566|M.tuberculosis_H37Rv ----YLVQLASDIEALDGPSGPAADFTDLHAWAEAYIPGAGWIGLDPTSG MMAR_2165|M.marinum_M ----YLVQLASDIEALDGPSGPTADFTDLHAWTEVYIPGAGWIGLDPTSG MUL_1749|M.ulcerans_Agy99 ----YLVQLASDIEALDGPSGPTADFTDLHAWTEVYIPGAGWIGLDPTSG MLBr_02678|M.leprae_Br4923 ATSYNCPPISRHSTSHRGLPPNSPTCTPGPKCPSPVRAKSGWTRSRGCSP :: . * . . * .. . :** * Mflv_3771|M.gilvum_PYR-GCK LFAGEGHIPLSATPHPESAAPITGATEPCETVLEFSNVVTRVHEDPRVTL Mvan_2628|M.vanbaalenii_PYR-1 LFAGEGHIPLSATPHPESAAPITGATEPCETTLEFSNVVTRVHEDPRVTL MSMEG_3016|M.smegmatis_MC2_155 LFAGEGHIPLSATPHPESAAPVTGATGVCEASLEFSNVVTRVHEDPRVTL MAB_2859c|M.abscessus_ATCC_199 LFAGEGHIPLSATPHPSTSAAITGATDMCESTLDFSNTVTRVHEDPRVTL Mb2595|M.bovis_AF2122/97 LLAGEGHIPLAATPHPASAAPISGGTDVCDTVLEFSNTVTRVHEDPRVTL Rv2566|M.tuberculosis_H37Rv LLAGEGHIPLAATPHPASAAPISGGTDVCDTVLEFSNTVTRVHEDPRVTL MMAR_2165|M.marinum_M LFAGEGHIPLAATPHPASAAPISGGTGVCNTVLEFSNTVTRVHEDPRVTL MUL_1749|M.ulcerans_Agy99 LFAGEGHIPLAATPHPASAAPISGGTGVCNTVLEFSNTVTRVHEDPRVTL MLBr_02678|M.leprae_Br4923 TRSAYRWQPHHILRRQRRPTAQPTRAKRCWTSLTLS---TQVQEDPHITL :. * : .:. . : * : * :* *:*:***::** Mflv_3771|M.gilvum_PYR-GCK PYTDASWAAINALGRRVDERLREADVRLTMGGEPTFVSIDNQVD---PEW Mvan_2628|M.vanbaalenii_PYR-1 PYTEESWAAINALGRRVDERLTAGDVRLTVGGEPTFVSIDNQVD---PEW MSMEG_3016|M.smegmatis_MC2_155 PYTDAAWASIVDLGGRVDRRLADADVRLTMGGEPTFVSIDNQVD---PEW MAB_2859c|M.abscessus_ATCC_199 PYTASAWEAVVALGEEIDARLDAAGVGLTMGGEPTFVSIDDQTS---EQW Mb2595|M.bovis_AF2122/97 PYTDESWKTICEVGQRVDERLAAADVRLTVGGEPTFVSVDNQVA---EEW Rv2566|M.tuberculosis_H37Rv PYTDESWKTICEVGQRVDERLAAADVRLTVGGEPTFVSVDNQVA---EEW MMAR_2165|M.marinum_M PYTDEAWQTICDVGRRVDERLAAGDVRLTMGGEPTFVSVDNQTD---KEW MUL_1749|M.ulcerans_Agy99 PYTDEAWQTICDVGRRVDERLAAGDVRLTMGGEPTFVSVDNQTD---KEW MLBr_02678|M.leprae_Br4923 PYSDVAWHAICAIG-------QHGYQRLTVGGKPTVVLVNIHPNKGRKEW **: :* :: :* . **:**:**.* :: : :* Mflv_3771|M.gilvum_PYR-GCK TTAADGPHKRERASALTARLKKVWAPQGLVQRSQGKWYPGEPLPRWQIGL Mvan_2628|M.vanbaalenii_PYR-1 TTDADGPHKRERASALAARLKKVWAPQGLVQRSQGKWYPGEPLPRWQIGL MSMEG_3016|M.smegmatis_MC2_155 TTDADGPHKRERASALAARLKNVWAPGGLVQRSQGKWYPGEPLPRWQIAL MAB_2859c|M.abscessus_ATCC_199 TTAADGEHKRARASDLAARLKAAWAPTGLVQRSQGKWYPGEPLPRWQIGL Mb2595|M.bovis_AF2122/97 RTAADGPHKRERASDLAARLKAVWAPQGLIHRGQGRWYPGEPLPRWQIAL Rv2566|M.tuberculosis_H37Rv RTAADGPHKRERASDLAARLKAVWAPQGLIHRGQGRWYPGEPLPRWQIAL MMAR_2165|M.marinum_M RTAADGPHKRSRASDLAARLKARWAPEGLVQRSQGRWYPGEPLPRWQIAL MUL_1749|M.ulcerans_Agy99 RTAADGPHKRSRASDLAARLKARWAPEGLVQRSQ-RHCP----------- MLBr_02678|M.leprae_Br4923 TMVAKSPSKRQPASDLTARLKAAWAPQGLIHFRQGQWYTGEPLPQWQITL *.. ** ** *:**** *** **:: * : . Mflv_3771|M.gilvum_PYR-GCK YWRADGEPLWSDDRLLADPWPET----PGVRGIAPDAHRALLAAIADGLG Mvan_2628|M.vanbaalenii_PYR-1 FWRTDGEPLWADESLLADPWQET----SDTRTPTPDAGHRLLAVIADGLG MSMEG_3016|M.smegmatis_MC2_155 YWRTDGLPLWTDAELLADPWSG------KTREVAPDAAERLLSEIAAGLG MAB_2859c|M.abscessus_ATCC_199 YWRRDGQPLWSDPELLADPWDGE-----RQWSTPQGADRALLSALASDLG Mb2595|M.bovis_AF2122/97 YWRTDGRPLWTNDALLADPWGA-----PPADPVDDDAAYRVLAGIADGLG Rv2566|M.tuberculosis_H37Rv YWRTDGRPLWTNDALLADPWGA-----PPADPVDDDAAYRVLAGIADGLG MMAR_2165|M.marinum_M YRRTDGRPLWTDPTLLADPW-L-----DPPTPVDSDAAHQVLSAFAEGMG MUL_1749|M.ulcerans_Agy99 LRRLIGR--------------------APPDPRD---------------- MLBr_02678|M.leprae_Br4923 YWRTKGQPLWTNDALLTDTWKAGPSERNKTTLEDSELAHKVLAQAADGLG * * Mflv_3771|M.gilvum_PYR-GCK LPADRVRPAYEDPLTRLIAAVRRPEGPPVAADDDLA----ADDAAGRAAL Mvan_2628|M.vanbaalenii_PYR-1 LPAGHVRPAYEDPLARLVGAVRQPAGPPVDADDDLA----VDSADGRAQL MSMEG_3016|M.smegmatis_MC2_155 LPGTQVRPAFEDPLSRLAAAVRLPAGDPVGADEDLA----EDGADARAEL MAB_2859c|M.abscessus_ATCC_199 LPDSQVRPAYEDPLSRLVASIRRPAGDPIDTADDPAP--YEDSAERRTGL Mb2595|M.bovis_AF2122/97 LPISQVRPAYEDPLSRLAAAVRMPAGDPVESGDDLGCDTNPDTPTGRAAL Rv2566|M.tuberculosis_H37Rv LPISQVRPAYEDPLSRLAAAVRMPAGDPVESGDDLGCDTNPDTPTGRAAL MMAR_2165|M.marinum_M LPLSQVRPAYEDPLARLAATVRLPSGDPVDPIDDLDPETDSDTPVGRAEL MUL_1749|M.ulcerans_Agy99 -------------------------------------------------- MLBr_02678|M.leprae_Br4923 LPLTQMRAAYKDTLRRLAAKVRIPSGAPVQLSDDRGP-TTPDSAVNRVAL Mflv_3771|M.gilvum_PYR-GCK MQRLDESVGEPTAFVLPLHRRDDDAGWASADWTLRRGRIVLLDGDSPAGL Mvan_2628|M.vanbaalenii_PYR-1 LARLEESVTEPSAFVLPVHRRDDDSGWAGAQWTLRRGRVVLLEGDSPAGL MSMEG_3016|M.smegmatis_MC2_155 LARLESPVDAPAAHVLPLHRADDGTGWASADWRLRRGRIVLLDGDSPAGL MAB_2859c|M.abscessus_ATCC_199 LDRLDEAVTQPTAYVLPLHRGED--GWESADWTLRRGRIVLTDGDSPAGL Mb2595|M.bovis_AF2122/97 LAPR---------------------------------------------- Rv2566|M.tuberculosis_H37Rv LARLDEAITSPAAYVLPLHRRDDGQGWASANWRLRRGRIVLLEGDSPAGL MMAR_2165|M.marinum_M LARLDASVTSAAAHVLPLHRREDGSGWASADWRLRRGRLVLIEGDSPAGL MUL_1749|M.ulcerans_Agy99 -----------------------------------RGR------------ MLBr_02678|M.leprae_Br4923 LTRLEESVTLPDAYMLSLHSRDDNLSWVQATLQLHRGCIVLIEDASLAGL Mflv_3771|M.gilvum_PYR-GCK RLPLNSISWKPPKPTFEADPIHRRPALGRGA-----ALARSATATPEETS Mvan_2628|M.vanbaalenii_PYR-1 RLPLHSISWQPPRPTFDADPIERRPPLPRAG-----SVTAAASPDMATTV MSMEG_3016|M.smegmatis_MC2_155 RLPLNSISWQPPRPSFEADPLAVD------------TDTEPAPGRRTATV MAB_2859c|M.abscessus_ATCC_199 RLPLDAVSWQPAPQSAEADPLSAP------------AELGAQRSPAPAVV Mb2595|M.bovis_AF2122/97 -------------------------------------------------- Rv2566|M.tuberculosis_H37Rv RLPLDSISWRPPRASFDADPVAVRSTLPAELHTDR------------AVV MMAR_2165|M.marinum_M RLPLNSISWQPPRTSFDVDPVTVGYALPEPATAEAV----------DAVL MUL_1749|M.ulcerans_Agy99 -------------------------------------------------- MLBr_02678|M.leprae_Br4923 LLPLDSISWPRPHVSFYLDPMTFWR------------AWSAEPNTAAAVL Mflv_3771|M.gilvum_PYR-GCK DDDEWVPTTALVGEIRDGLLYVFLPPVDELEHFIDLIARIESAAASIDCP Mvan_2628|M.vanbaalenii_PYR-1 EDADWVPTTALVGEIRDGLLYVFLPPTEELEHFVDLVERIEAAAAAIDCP MSMEG_3016|M.smegmatis_MC2_155 VDADGAPTTALVAEIRDGLLYVFLPPTAELDDFLDLVARVEAAAAAVGVP MAB_2859c|M.abscessus_ATCC_199 VPAEGAPVTALVAEIRDGLLYLFLPPLEQVDDFVDLIARVEAAVT---CP Mb2595|M.bovis_AF2122/97 -------------------------------------------------- Rv2566|M.tuberculosis_H37Rv EDPETAPTTALVAEVRGGLVHIFLPPTDALEHFIDLVARVEAAATTANCP MMAR_2165|M.marinum_M DDSENAPPTAIVAEVRDGLLYIFIPPTEALEDFVDLVTRIEAAAAKANCP MUL_1749|M.ulcerans_Agy99 -------------------------------------------------- MLBr_02678|M.leprae_Br4923 ENPDSAPPTAMVAEIRGEFLSIFLSPTETLKHFVSLVSGGETAAANIGCP Mflv_3771|M.gilvum_PYR-GCK VVIEGYGPPPDPRLTTMSITPDPGVIEVNVAPTESFVEQRAQLETLYREA Mvan_2628|M.vanbaalenii_PYR-1 VVIEGYGPPNDARLSSVTITPDPGVIEVNVAPTASFAEQRAQLETLYAEA MSMEG_3016|M.smegmatis_MC2_155 VVVEGYGPPTDPRITSTTITPDPGVIEVNVAPTASFGEQNKQLETLYEQA MAB_2859c|M.abscessus_ATCC_199 LVIEGYGPPPDPRIEAMSITPDPGVIEVNVTPTASFAEQSRQLQVLYEEA Mb2595|M.bovis_AF2122/97 -------------------------------------------------- Rv2566|M.tuberculosis_H37Rv VVIEGYGPPPDPRLTSTTITPDPGVIEVNIAPTASFAEQRQQLETLYQQA MMAR_2165|M.marinum_M LVLEGYGPPPDPRLESTTITPDPGVIEVNVAPTASFEEQRQQLETLYEEA MUL_1749|M.ulcerans_Agy99 -------PPP---------------------------------------- MLBr_02678|M.leprae_Br4923 VVIEGYGLPTDLRLKSMCVKPG------QVAAAASFAAERQQLETFYAQA Mflv_3771|M.gilvum_PYR-GCK RLARLSTEAFDVDGTHGGTGGGNHITLGGVTPADSPLLRRPDLLVSMLTY Mvan_2628|M.vanbaalenii_PYR-1 RLARLSTESFDVDGSHGGTGGGNHITLGGITPADSPLLRRPDLLVSLLTY MSMEG_3016|M.smegmatis_MC2_155 RLARLSTESFDVDGTHSGTGGGNHITLGGITPADSPLLRRPDLLVSLLTY MAB_2859c|M.abscessus_ATCC_199 RKARLTTESFDVDGTHTGTGGGNHITLGGRTPATSPLLRRPDLLVSLLTY Mb2595|M.bovis_AF2122/97 -------------------------------------------------- Rv2566|M.tuberculosis_H37Rv RLARLTTEAFDVDGTHGGTGGGNHITLGGVTPADSPLLRRPDLLVSLLTY MMAR_2165|M.marinum_M RLARLSTESFDVDGSHGGTGGGNHITLGGVTPADSPLLRRPDLLVSLLTY MUL_1749|M.ulcerans_Agy99 -------------------------------------------------- MLBr_02678|M.leprae_Br4923 GMARLSTESFDDSGAHGRTGGNNHITLGDVTP----LRRHPDLLVSLLTC Mflv_3771|M.gilvum_PYR-GCK WQRHPALSYLFAGRFIGTTSQSPRVDEGRPDALYELEIAFAEIARLSKAE Mvan_2628|M.vanbaalenii_PYR-1 WQRHPSLSYLFAGRFIGTTSQAPRVDEGRPESLYELEIAFAEIARLAQAP MSMEG_3016|M.smegmatis_MC2_155 WQRHPALSYLFAGRFIGTTSQAPRVDEGRAEALYELEIAFAEIARLTATD MAB_2859c|M.abscessus_ATCC_199 WQHHPALSYLFSGRFVGTTSQAPRVDEGREEALYELEIAFAEIERLADSE Mb2595|M.bovis_AF2122/97 -------------------------------------------------- Rv2566|M.tuberculosis_H37Rv WQRHPSLSYLFAGRFVGTTSQAPRVDEGRAEALYELEIAFAEILRLSPSS MMAR_2165|M.marinum_M WQRHPSLSYVFAGRFVGTTSQAPRVDEGRAEALYELEIAFAEIA---RLS MUL_1749|M.ulcerans_Agy99 -------------------------------------------------- MLBr_02678|M.leprae_Br4923 WQRHPSRSYRFAGQFVGPISQAPQVDEVR--------------------- Mflv_3771|M.gilvum_PYR-GCK G---GAAPEHGRSASSAPEHGRSASSAPPWLVDRALRHLLTDITGNTHRA Mvan_2628|M.vanbaalenii_PYR-1 G---GAK---------------------AWVTDRALRHLLTDITGNTHRA MSMEG_3016|M.smegmatis_MC2_155 A---PQP----------------------WVLDRALRHLLTDITGNTHRA MAB_2859c|M.abscessus_ATCC_199 A---PWH------------------------IDRSLRHLLTDITGNTHRA Mb2595|M.bovis_AF2122/97 -------------------------------------------------- Rv2566|M.tuberculosis_H37Rv GGGR----------------------PQPWVTDRALRHLLTDITGNTHRA MMAR_2165|M.marinum_M AGGA----------------------AKPWVTDRALRHLLTDITGNTHRA MUL_1749|M.ulcerans_Agy99 -----------------------------------LRGHLQRLPG----- MLBr_02678|M.leprae_Br4923 ----------------------------------AFRHLVVDITGNIHHA Mflv_3771|M.gilvum_PYR-GCK EFCIDKLYSPDSARGRLGLLELRGFEMPPHPQMAMVQSLLVRSLVAWFWD Mvan_2628|M.vanbaalenii_PYR-1 EFCIDKLYSPDSARGRLGLLELRGFEMPPHHQMAMVQSLLVRALVAWFWE MSMEG_3016|M.smegmatis_MC2_155 EFCIDKLYSPDGARGRLGLLELRGFEMPPHHQMAMVQALLVRSLVAWFWD MAB_2859c|M.abscessus_ATCC_199 EFCIDKLYSPDSARGRLGLLELRGFEMPPHFQMAMVQSLLVRALVARFWA Mb2595|M.bovis_AF2122/97 -------------------------------------------------- Rv2566|M.tuberculosis_H37Rv EFCIDKLYSPDSARGRLGLLELRGFEMPPHLHMAMVQSLLVRSLVAWFWD MMAR_2165|M.marinum_M EFCIDKLYSPEGTRGRLGLLELRGFEMPPHLRMAMVQSLLVRSLVAWFWE MUL_1749|M.ulcerans_Agy99 --------APAG-------------------------------------- MLBr_02678|M.leprae_Br4923 EFCIDKLHSHDNTHGRLSLLELRGFAMPLYLQMVIVRWLLVRSLVAWFWE Mflv_3771|M.gilvum_PYR-GCK EPLRAPLIRHGANLHGRYLLPHFLIHDIAEVAADLRAHGVEFDTSWLDPF Mvan_2628|M.vanbaalenii_PYR-1 EPLRAPLIRHGANLHGRYLLPHFLIHDIAEVAADLRAHGVEFDTSWLDPF MSMEG_3016|M.smegmatis_MC2_155 EPLRAPLIRHGANLHGRYLLPHFLIRDIADVAADLRAHGIDFLTSWLDPF MAB_2859c|M.abscessus_ATCC_199 QPLSAPLVRHGANLHGRYLLPHFIIHDIAQVAADLRAHDIAFETSWLDPF Mb2595|M.bovis_AF2122/97 -------------------------------------------------- Rv2566|M.tuberculosis_H37Rv QPLRAPLIRHGANLHGRYLLPHFLIHDIADVAADLRAHGIAFETSWLDPF MMAR_2165|M.marinum_M QPLRAPLIRHGANLHGRYLLPHFLIHDIADVAADLRANGIDFETSWLDPF MUL_1749|M.ulcerans_Agy99 -------------------------------------------------- MLBr_02678|M.leprae_Br4923 EPLRASVIRHGTNLHGRYLFPHFVSHDMAAIATSLREHGLAFETNWLYPF Mflv_3771|M.gilvum_PYR-GCK TEFRFPRIGTAVLGGVEIELRGAIEPWNVLGEESTAGGTARYVDSSVERL Mvan_2628|M.vanbaalenii_PYR-1 TEFRFPRIGTAVLGGVELELRDAIEPWNVLGEEATAGGTARYVDSSVERL MSMEG_3016|M.smegmatis_MC2_155 TEFRFPRIGTAVFDGVELELRGAIEPWNVLGEESTAGGTARYVDSSVERI MAB_2859c|M.abscessus_ATCC_199 TEFRFPRIGTAVFDGIEIELRGAIEPWRVLGEEATSGGTARYVDSSIERV Mb2595|M.bovis_AF2122/97 -------------------------------------------------- Rv2566|M.tuberculosis_H37Rv TEFRFPRIGTAVFDGIEIELRGAIEPWHTLGEEATAAGTARYVDSSVERI MMAR_2165|M.marinum_M TEFRFPRIGTAVFDGVEIELRGAIEPWNTLGEESTASGTARYVDSSVERL MUL_1749|M.ulcerans_Agy99 -------------------------------------------------- MLBr_02678|M.leprae_Br4923 IEFRLPRLGTSVFHGVEIELRNAIEPWTTFG------------------- Mflv_3771|M.gilvum_PYR-GCK QVRLIGADRSRYLVTVNGHPVPMLATDNPDVQVGGVRYRAWQPPSALHPT Mvan_2628|M.vanbaalenii_PYR-1 QVRLIGADRQRHVVVVNGFPVPLLATDNPDVQVGGVRYRAWQPPSALHPT MSMEG_3016|M.smegmatis_MC2_155 QVRLVGADRDRYVVTANGHPIPLLATEKSDVQVGGVRYRAWQPPSALHPS MAB_2859c|M.abscessus_ATCC_199 QVRVIGADRSRYVVTCNGEPIPLLSTENPDVQVAGVRYRAWQPPSALHPS Mb2595|M.bovis_AF2122/97 -------------------------------------------------- Rv2566|M.tuberculosis_H37Rv QVRIIGADRHRYVVTCNGYPMPLLATDNPDIHVGGVRFKAWQPPSALHPT MMAR_2165|M.marinum_M QIRVIGADRHRYVVTCNGYPVPLLATDNPDIHVGGVRFKAWQPPSALHPT MUL_1749|M.ulcerans_Agy99 -------------------------HDNPDIHVGGVRFKAWQPPSALHPT MLBr_02678|M.leprae_Br4923 -------------------------------------------------- Mflv_3771|M.gilvum_PYR-GCK ITVDGPLRFELIDAATGVSRGGCTYHVSHPGGRSYDSPPVNAVEAESRRA Mvan_2628|M.vanbaalenii_PYR-1 ITVDGPLRFELVDAAAGVSRGGCTYHVSHPGGRSYDRPPVNAVEAESRRG MSMEG_3016|M.smegmatis_MC2_155 ITVDGPLRFELIDTATGTSKGGCTYHIVHPGGRSYDTSPVNAVEAESRRG MAB_2859c|M.abscessus_ATCC_199 ITVDDPLRFELIDTANALSRGGCTYHVSHPGGRSYDDPPVNAVAAEARRG Mb2595|M.bovis_AF2122/97 -------------------------------------------------- Rv2566|M.tuberculosis_H37Rv ITVDGPLRFELIDIATATSCGGCTYHVAHPGGRAYDEPPVNAVEAEARRA MMAR_2165|M.marinum_M ISADGPLQFELIDLTAGTSRGGCTYHVTHPGGLAYDEPPVNAVTAESRRA MUL_1749|M.ulcerans_Agy99 FSADGPLQFELIDLTAGTSRGGCTYHVTHPGGLAYDEPPVNAVTAESRRA MLBr_02678|M.leprae_Br4923 ------------EKSTVTSRGGCTYHASHTGSKAINTG--STLEAQARWS Mflv_3771|M.gilvum_PYR-GCK RRFEATGFTPGAVDLAALREKLARQSTDVGAPGILDLRRVRTVLQ-- Mvan_2628|M.vanbaalenii_PYR-1 RRFEATGFTPGRVDLADLREKQARQSTDVGAPGILDLRRVRTVLQ-- MSMEG_3016|M.smegmatis_MC2_155 RRFEVIGFTPGKVDMSVIRERQARQSTDVGAPGILDLRRVRTVLR-- MAB_2859c|M.abscessus_ATCC_199 RRFDATGYTTGRVDLSDLREKQARMSTDAVAPGILDLRRARTVGRR- Mb2595|M.bovis_AF2122/97 ----------------------------------------------- Rv2566|M.tuberculosis_H37Rv RRFEATGFTPGKLDLSDIREKQARISTDIGAPGILDLRRVRTVQQ-- MMAR_2165|M.marinum_M RRFEATGFTPGKLDLSDIREKQARMFTDIGAPGILDLRRVRTVQQ-- MUL_1749|M.ulcerans_Agy99 RRFEATGFTPGKLDLSDIREKQARMFTDIGAPGILDLRRVRTVQQ-- MLBr_02678|M.leprae_Br4923 RRFEATGFIPSKITMSCIRK-----SKSVSPPTSTRLASSTSDASAP