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MSGSSSRSFVHLHNHTEYSMLDGAAKITPMLAEVERLDMPAIGMTDHGNMFGASEFYNSATKAGVKPIIG VEAYVAPGSRFDTRRITWGDPSQKGDDVSGSGSYTHLTMVAENATGLRNLFKLSSLASFEGQLGKWSRMD AELVAEHAEGIIATTGCPSGEVQTRLRLGHDREALESAAKWREIFGADNYFLELMDHGLSIERRVREGLI EIGRKLDIPPLATNDCHYVTRDAAHNHEALLCVQTGKTLSDPNRFKFDGDGYYLKSAAEMRQLWDDDIPG ACDSTLLIAERVQSYADVWTPRDRMPIFPVPEGHDPASWLHHEVMAGLRRRFPSGLGQDYIDRAEYEIKV ICDKGFPSYFLIVADLINYARSVDIRVGPGRGSAAGSLVAYAMGITNIDPIPHGLLFERFLNPERPSAPD IDIDFDDRRRGEMVRYAADKWGQDRVAQVITFGTIKTKAALKDSARIHYGQPGFAIADRITKALPPPIMA KDIPLSGITDPAHERFKEAAEVRGLIETDPDVRTIYQTARGLEGLIRNAGVHACAVIMSSEPLTEAIPLW KRPQDGAIITGWDYPSCEAIGLLKMDFLGLRNLTIIGDAIENIEANRGIDLDLESLPLDDKPTYELLGRG ETLGVFQLDGGPMRDLLRRMQPTEFNDIVAVLALYRPGPMGMNAHNDYADRKNNRQAVKPIHPELEEPLR EILSETYGLIVYQEQIMFIAQKVASYTMGKADALRKAMGKKKLEVLEAEYKGFYEGMTANGFSEKAVKAL WDTILPFAGYAFNKSHAAGYGLVSYWTAYLKANYPAEYMAGLLTSVGDDKDKAAVYLADCRKLGITVLPP DVNESLVNFASVGQDIRFGLGAVRNVGANVVGSLIGTRSGKGKFTDFSDYLNKIDISACNKKVTESLIKA GAFDSLGHPRKGLFLVHTDAVDSVLGTKKAEAMGQFDLFGGSDSGADAVFTIKVPEDEWEDKHKLALERE MLGLYVSGHPLNGVAHLLATQVDTAIPAILDGDVSNDAQVRVGGILAAVNRRVNKNGMPWASAQLEDLTG GIEVMFFPHTYSNYGADIADDAVVLVNAKVAIRDDRISLIANELVVPDFSNAQADRPLAVSLPTRQCTID KVTALKQVLARHPGTSQVHLRLISGDRITTLELDQSLRVTPSPALMGDLKELLGPGCLGS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_1545 | dnaE | - | 100% (1180) | DNA polymerase III subunit alpha |
| M. ulcerans Agy99 | MUL_0923 | dnaE2 | e-117 | 28.26% (1104) | error-prone DNA polymerase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1574 | dnaE | 0.0 | 90.20% (1184) | DNA polymerase III subunit alpha |
| M. gilvum PYR-GCK | Mflv_3636 | dnaE | 0.0 | 87.38% (1181) | DNA polymerase III subunit alpha |
| M. tuberculosis H37Rv | Rv1547 | dnaE | 0.0 | 90.20% (1184) | DNA polymerase III subunit alpha |
| M. leprae Br4923 | MLBr_01207 | dnaE | 0.0 | 88.74% (1172) | DNA polymerase III subunit alpha |
| M. abscessus ATCC 19977 | MAB_2696c | dnaE | 0.0 | 85.28% (1182) | DNA polymerase III subunit alpha |
| M. marinum M | MMAR_2369 | dnaE | 0.0 | 99.83% (1180) | DNA polymerase III, alpha subunit, DnaE1 |
| M. avium 104 | MAV_3224 | dnaE | 0.0 | 94.45% (1172) | DNA polymerase III subunit alpha |
| M. smegmatis MC2 155 | MSMEG_3178 | dnaE | 0.0 | 89.82% (1179) | DNA polymerase III subunit alpha |
| M. thermoresistible (build 8) | TH_0581 | - | 0.0 | 86.15% (1177) | DNA polymerase III alpha subunit |
| M. vanbaalenii PYR-1 | Mvan_2777 | dnaE | 0.0 | 89.07% (1180) | DNA polymerase III subunit alpha |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_1545|M.ulcerans_Agy99 ------MSGSSSRSFVHLHNHTEYSMLDGAAKITPMLAEVERLDMPAIGM
MMAR_2369|M.marinum_M ------MSGSSSRSFVHLHNHTEYSMLDGAAKITPMLAEVERLDMPAIGM
MAV_3224|M.avium_104 ------MNHSS---FVHLHNHTEYSMLDGAAKITPMLAEVERLGMPAVGM
Mb1574|M.bovis_AF2122/97 --MSGSSAGSS---FVHLHNHTEYSMLDGAAKITPMLAEVERLGMPAVGM
Rv1547|M.tuberculosis_H37Rv --MSGSSAGSS---FVHLHNHTEYSMLDGAAKITPMLAEVERLGMPAVGM
MLBr_01207|M.leprae_Br4923 ------MNQSS---FVHLHNHTEYSMLDGAAKITPMFAEVERLQMPAVGM
TH_0581|M.thermoresistible__bu -------MSSS---FVHLHNHTEFSMLDGAAKIGPLLAEAQRLEMSAIGM
Mflv_3636|M.gilvum_PYR-GCK -------MSGS---FVHLHNHTEYSMLDGAAKVKPMLAEAQRLEMPAIGM
Mvan_2777|M.vanbaalenii_PYR-1 -------MSGS---FVHLHNHTEYSMLDGAAKVKPMLAEAQRLEMPAIGM
MSMEG_3178|M.smegmatis_MC2_155 MSGTDGRSSGS---FVHLHNHTEYSMLDGAAKITPMLAEAQRLEMPAIGM
MAB_2696c|M.abscessus_ATCC_199 ----MSSSNSS---FVHLHNHTEYSMLDGAAKIKPMLAEVERLGMSAVGM
.* *********:********: *::**.:** *.*:**
MUL_1545|M.ulcerans_Agy99 TDHGNMFGASEFYNSATKAGVKPIIGVEAYVAPGSRFDTRRITWGDPSQK
MMAR_2369|M.marinum_M TDHGNMFGASEFYNSATKAGVKPIIGVEAYVAPGSRFDTRRITWGDPSQK
MAV_3224|M.avium_104 TDHGNMFGASEFYNAATKAGIKPIIGVEAYIAPGSRFDTRRILWGDPSQK
Mb1574|M.bovis_AF2122/97 TDHGNMFGASEFYNSATKAGIKPIIGVEAYIAPGSRFDTRRILWGDPSQK
Rv1547|M.tuberculosis_H37Rv TDHGNMFGASEFYNSATKAGIKPIIGVEAYIAPGSRFDTRRILWGDPSQK
MLBr_01207|M.leprae_Br4923 TDHGNMFGASEFYNTAIKAGIKPIIGVEAYIAPGSRFDTRRITWGDPSQK
TH_0581|M.thermoresistible__bu TDHGNMFGASEFYNAATDAGIKPIIGVEAYIAPGSRFDTKRVQWGDPSQK
Mflv_3636|M.gilvum_PYR-GCK TDHGNMFGASEFYNAATDAGIKPIIGIEAYIAPASRFDTKRVLWGDPGQK
Mvan_2777|M.vanbaalenii_PYR-1 TDHGNMFGASEFYNAATDAGIKPIIGIEAYIAPASRFETKRVLWGDPSQK
MSMEG_3178|M.smegmatis_MC2_155 TDHGNMFGASEFYNSATKAGIKPIIGIEAYIAPGSRFDTKRVTWGDPGQK
MAB_2696c|M.abscessus_ATCC_199 TDHGNMYGASEFYNVAAATGVKPIIGIEAYIAPASRFDTKRVFWGDPGQK
******:******* * :*:*****:***:**.***:*:*: ****.**
MUL_1545|M.ulcerans_Agy99 GDDVSGSGSYTHLTMVAENATGLRNLFKLSSLASFEGQLGKWSRMDAELV
MMAR_2369|M.marinum_M GDDVSGSGSYTHLTMVAENATGLRNLFKLSSLASFEGQLGKWSRMDAELV
MAV_3224|M.avium_104 ADDVSGSGSYTHLTMVAENAAGLRNLFKLSSLASFEGQLGKWSRMDAELI
Mb1574|M.bovis_AF2122/97 ADDVSGSGSYTHLTMMAENATGLRNLFKLSSHASFEGQLSKWSRMDAELI
Rv1547|M.tuberculosis_H37Rv ADDVSGSGSYTHLTMMAENATGLRNLFKLSSHASFEGQLSKWSRMDAELI
MLBr_01207|M.leprae_Br4923 ADDVSAGGAYTHLTMVAENAAGLRNLFKLSSLASFEGQLSKWSRMDAELI
TH_0581|M.thermoresistible__bu SDDVSGSGAYTHMTMVAETADGLRNMFKLSSLASFEGQLGKWSRMDAELI
Mflv_3636|M.gilvum_PYR-GCK SDDVSGSGSYTHMTMVAENATGLRNLFKLSSLASFEGQLGKWSRMDAEII
Mvan_2777|M.vanbaalenii_PYR-1 SDDVSGGGSYTHMTMVAENATGLRNLFKLSSLASFEGQLGKWARMDAEII
MSMEG_3178|M.smegmatis_MC2_155 GDDVSGSGAYTHMTMVAENATGLRNLFKLSSLASFEGQLGKWSRMDAEII
MAB_2696c|M.abscessus_ATCC_199 SDDVSGSGSYTHMTMVAENATGLRNLFKLSSLASFEGQLGKWARMDADLI
.****..*:***:**:**.* ****:***** *******.**:****:::
MUL_1545|M.ulcerans_Agy99 AEHAEGIIATTGCPSGEVQTRLRLGHDREALESAAKWREIFGADNYFLEL
MMAR_2369|M.marinum_M AEHAEGIIATTGCPSGEVQTRLRLGHDREALESAAKWREIFGADNYFLEL
MAV_3224|M.avium_104 AEHADGIIATTGCPSGEVQTRLRLGQDREALESAAKWREIFGADNFFLEL
Mb1574|M.bovis_AF2122/97 AEHAEGIIITTGCPSGEVQTRLRLGQDREALEAAAKWREIVGPDNYFLEL
Rv1547|M.tuberculosis_H37Rv AEHAEGIIITTGCPSGEVQTRLRLGQDREALEAAAKWREIVGPDNYFLEL
MLBr_01207|M.leprae_Br4923 GEYAEGIIVTTGCPSGEVQTRLRLGHDREALESAAKWREIVGPDNYFLEL
TH_0581|M.thermoresistible__bu AEHATGIIATTGCPSGEVQTRLRLGHHREALEAAAKWRDIFGPDNYFLEL
Mflv_3636|M.gilvum_PYR-GCK AEHAEGIIATTGCPSGEVQTRLRLGHDREALEAAARWREIFGPENFFLEL
Mvan_2777|M.vanbaalenii_PYR-1 AEHAEGIIATTGCPSGEVQTRLRLGHDREALEAAARWREIFGPENFFLEL
MSMEG_3178|M.smegmatis_MC2_155 AEHAEGIIATTGCPSGEVQTRLRLGHEREALEAAAKWREIFGPENFFLEL
MAB_2696c|M.abscessus_ATCC_199 AEHASGIIATTGCPSGEVQTRLRLGQESEALAAAAKWQDIFGKDNFFLEL
.*:* *** ****************:. *** :**:*::*.* :*:****
MUL_1545|M.ulcerans_Agy99 MDHGLSIERRVREGLIEIGRKLDIPPLATNDCHYVTRDAAHNHEALLCVQ
MMAR_2369|M.marinum_M MDHGLSIERRVREGLIEIGRKLDIPPLATNDCHYVTRDAAHNHEALLCVQ
MAV_3224|M.avium_104 MDHGLSIEQRVRGGLLEIGRKLNIPPLATNDCHYVTRDAAHNHEALLCVQ
Mb1574|M.bovis_AF2122/97 MDHGLTIERRVRDGLLEIGRALNIPPLATNDCHYVTRDAAHNHEALLCVQ
Rv1547|M.tuberculosis_H37Rv MDHGLTIERRVRDGLLEIGRALNIPPLATNDCHYVTRDAAHNHEALLCVQ
MLBr_01207|M.leprae_Br4923 MDHGLSIEQRVREGLLNIGRKLNIPPLATNDCHYVTRDAVHNHEALLCVQ
TH_0581|M.thermoresistible__bu MDHGLDIERRVRDGLLEIGRKLNIPPLATNDCHYVTRDAAQNHEALLCVQ
Mflv_3636|M.gilvum_PYR-GCK MDHGLDIERRVREGLLEIGQKLGIPPLATNDCHYVTRDASQNHEALLCIQ
Mvan_2777|M.vanbaalenii_PYR-1 MDHGLDIERRVREGLLDIGQKLGIPPLATNDCHYVTRDAAQNHEALLCIQ
MSMEG_3178|M.smegmatis_MC2_155 MDHGLDIERRVREGLLEIGRKLGIPPLATNDCHYVTREAARNHEALLCVQ
MAB_2696c|M.abscessus_ATCC_199 MDHGLSIERRVREGLLEVGKKLGIPPLATNDCHYVTKDHAHNHEALLCVQ
***** **:*** **:::*: *.*************:: :*******:*
MUL_1545|M.ulcerans_Agy99 TGKTLSDPNRFKFDGDGYYLKSAAEMRQLWDDDIPGACDSTLLIAERVQS
MMAR_2369|M.marinum_M TGKTLSDPNRFKFDGDGYYLKSAAEMRQLWDDDIPGACDSTLLIAERVQS
MAV_3224|M.avium_104 TGKTLSDPNRFKFDGDGYYLKSAAEMRQIWDAEVPGACDSTLLIAERVQS
Mb1574|M.bovis_AF2122/97 TGKTLSDPNRFKFDGDGYYLKSAAEMRQIWDDEVPGACDSTLLIAERVQS
Rv1547|M.tuberculosis_H37Rv TGKTLSDPNRFKFDGDGYYLKSAAEMRQIWDDEVPGACDSTLLIAERVQS
MLBr_01207|M.leprae_Br4923 TGKTLSDPNRFKFHGDGYYLKSAAEMRQLWDDEVPGACDSTLLIAERVQS
TH_0581|M.thermoresistible__bu TGKTLSDPNRFKFDGDGYYLKSAAEMRALWDDEVPGACDNTLLIAERVQS
Mflv_3636|M.gilvum_PYR-GCK TGKTLSDPNRFKFDGDGYYLKSAAEMRALWDGQVPGACDSTLLIAERVQP
Mvan_2777|M.vanbaalenii_PYR-1 TGKTLSDPNRFKFDGDGYFLKSAAEMRALWDGQVPGACDSTLLIAERVQS
MSMEG_3178|M.smegmatis_MC2_155 TGKTLSDPTRFKFDGDGYFLKSAEEMRALWDSQVPGACDSTLLIGERVQS
MAB_2696c|M.abscessus_ATCC_199 TGKTLSDPTRFKFDGDGYYLKPASEMRDLWDDAVPGACDNTLLIAERVQS
********.****.****:**.* *** :** :*****.****.****.
MUL_1545|M.ulcerans_Agy99 YADVWTPRDRMPIFPVPEGHDPASWLHHEVMAGL-RRRFPSGL----GQD
MMAR_2369|M.marinum_M YADVWTPRDRMPIFPVPEGHDPASWLHHEVMAGL-RRRFPSGL----GQD
MAV_3224|M.avium_104 YAEVWTPRDRMPVFPVPEGHDQASWLHHEVMAGL-RRRFPDGV----GQD
Mb1574|M.bovis_AF2122/97 YADVWTPRDRMPVFPVPDGHDQASWLRHEVDAGL-RRRFPAGP----PDG
Rv1547|M.tuberculosis_H37Rv YADVWTPRDRMPVFPVPDGHDQASWLRHEVDAGL-RRRFPAGP----PDG
MLBr_01207|M.leprae_Br4923 YADVWEPRNRMPVFPVPVGHDQASWLRHEVDAGL-KRRFPDGP----PNG
TH_0581|M.thermoresistible__bu YADVWTPRDRMPVFPVPEGHTQESWLRHEVRAGL-QRRFPDGV----PQE
Mflv_3636|M.gilvum_PYR-GCK YTDVWAPKDRMPVFPVPEGHDQGSWLTHEVMAGL-ERRFSAAAGGQVPPE
Mvan_2777|M.vanbaalenii_PYR-1 YADVWTPKDRMPIFPVPEGHDQGSWLTHEVMTGLQERRFHGAP---VPQE
MSMEG_3178|M.smegmatis_MC2_155 YADVWEPRDRMPVFPVPEGHDQASWLTHEVKAGL-ERRFRGGP---VPEE
MAB_2696c|M.abscessus_ATCC_199 YEDVWNFKDRMPIFPVPEGEDQDSWLRKEVDRGL-ERRFEGVPGG-VPDE
* :** ::***:**** *. *** :** ** .***
MUL_1545|M.ulcerans_Agy99 YIDRAEYEIKVICDKGFPSYFLIVADLINYARSVDIRVGPGRGSAAGSLV
MMAR_2369|M.marinum_M YIDRAEYEIKVICDKGFPSYFLIVADLINYARSVDIRVGPGRGSAAGSLV
MAV_3224|M.avium_104 YIDRAEYEIKVICDKGFPSYFLIVADLINYARSVDIRVGPGRGSAAGSLV
Mb1574|M.bovis_AF2122/97 YRERAAYEIDVICSKGFPSYFLIVADLISYARSAGIRVGPGRGSAAGSLV
Rv1547|M.tuberculosis_H37Rv YRERAAYEIDVICSKGFPSYFLIVADLISYARSAGIRVGPGRGSAAGSLV
MLBr_01207|M.leprae_Br4923 YVERAAYEIDVICDKGFPAYFLIVADLVNHARSVGIRVGPGRGSAAGSLA
TH_0581|M.thermoresistible__bu YLDRAEYEIEVICAKGYPSYFLIVADLVNYARSVDIRVGPGRGSAAGSLV
Mflv_3636|M.gilvum_PYR-GCK YIERADYEIKVICDKGFPAYFLIVADLINYAKSVGIRVGPGRGSAAGSLV
Mvan_2777|M.vanbaalenii_PYR-1 YIDRAQYEIKVICDKGFPAYFLIVADLINYARSVGIRVGPGRGSAAGSLV
MSMEG_3178|M.smegmatis_MC2_155 YTTRAEYEIKVICDKGFPSYFLIVADLINYARSVGIRVGPGRGSAAGSLV
MAB_2696c|M.abscessus_ATCC_199 YFTRAHYELDVIKQKGFPAYFLVVGDLVSHAKEVGIRVGPGRGSAAGSLV
* ** **:.** **:*:***:*.**:.:*:...**************.
MUL_1545|M.ulcerans_Agy99 AYAMGITNIDPIPHGLLFERFLNPERPSAPDIDIDFDDRRRGEMVRYAAD
MMAR_2369|M.marinum_M AYAMGITNIDPIPHGLLFERFLNPERPSAPDIDIDFDDRRRGEMVRYAAD
MAV_3224|M.avium_104 AYALGITNIDPIPHGLLFERFLNPERPSAPDIDIDFDDRRRGEMVRYAAD
Mb1574|M.bovis_AF2122/97 AYALGITDIDPIPHGLLFERFLNPERTSMPDIDIDFDDRRRGEMVRYAAD
Rv1547|M.tuberculosis_H37Rv AYALGITDIDPIPHGLLFERFLNPERTSMPDIDIDFDDRRRGEMVRYAAD
MLBr_01207|M.leprae_Br4923 AYALGITDIDPIPHGLLFERFLNPERTSMPDIDIDFDDRRRGEMVRYAAD
TH_0581|M.thermoresistible__bu AYALRITDIDPIEHGLLFERFLNPERASMPDIDIDFDDRRRGEMVRYAAE
Mflv_3636|M.gilvum_PYR-GCK AYAMGITNIDPIPHGLLFERFLNPERPSAPDIDIDFDDRRRGEMLRYAAN
Mvan_2777|M.vanbaalenii_PYR-1 AYAMGITNIDPIPHGLLFERFLNPERPSAPDIDIDFDDRRRGEMLRYAAN
MSMEG_3178|M.smegmatis_MC2_155 AYALGITNIDPIPHGLLFERFLNPERPSAPDIDIDFDDRRRGEMLRYAAN
MAB_2696c|M.abscessus_ATCC_199 AYALGITNIDPIPHGLLFERFLNPERPSAPDIDIDFDDRRRGEMVRYATE
***: **:**** *************.* ***************:***::
MUL_1545|M.ulcerans_Agy99 KWGQDRVAQVITFGTIKTKAALKDSARIHYGQPGFAIADRITKALPPPIM
MMAR_2369|M.marinum_M KWGQDRVAQVITFGTIKTKAALKDSARIHYGQPGFAIADRITKALPPPIM
MAV_3224|M.avium_104 KWGSDRVAQVITFGTIKTKAALKDSARIHYGQPGFAIADRITKALPPPIM
Mb1574|M.bovis_AF2122/97 KWGHDRVAQVITFGTIKTKAALKDSARIHYGQPGFAIADRITKALPPAIM
Rv1547|M.tuberculosis_H37Rv KWGHDRVAQVITFGTIKTKAALKDSARIHYGQPGFAIADRITKALPPAIM
MLBr_01207|M.leprae_Br4923 KWGHDRVAQVITFGTIKTKAALKDSARIHYGQPGFAMADRITKALPPAIM
TH_0581|M.thermoresistible__bu KWGHERVAQVITFGTIKTKAALKDAARVHYGQPGFAIADRITKALPPPIM
Mflv_3636|M.gilvum_PYR-GCK KWGSDRVAQVITFGTIKTKAALKDSARVHYGQPGFAIADRITKALPPPIM
Mvan_2777|M.vanbaalenii_PYR-1 KWGSDRVAQVITFGTIKTKAALKDSARVHYGQPGFAIADRITKALPPPIM
MSMEG_3178|M.smegmatis_MC2_155 RWGSERVAQVITFGTIKTKAALKDSARVNFGQPGFAIADRITKALPPPIM
MAB_2696c|M.abscessus_ATCC_199 KWGSDRVAQVITFGTIKTKAALKDSARIHYGQPGFAIADRITKALPPPIM
:** :*******************:**:::******:**********.**
MUL_1545|M.ulcerans_Agy99 AKDIPLSGITDPAHERFKEAAEVRGLIETDPDVRTIYQTARGLEGLIRNA
MMAR_2369|M.marinum_M AKDIPLSGITDPAHERFKEAAEVRGLIETDPDVRTIYQTARGLEGLIRNA
MAV_3224|M.avium_104 AKDIPLSGITDPSHERYKEAAEVRGLIETDPDVRTIYQTARGLEGLIRNA
Mb1574|M.bovis_AF2122/97 AKDIPLSGITDPSHERYKEAAEVRGLIETDPDVRTIYQTARGLEGLIRNA
Rv1547|M.tuberculosis_H37Rv AKDIPLSGITDPSHERYKEAAEVRGLIETDPDVRTIYQTARGLEGLIRNA
MLBr_01207|M.leprae_Br4923 AKDIPLSGITDPAHERFKEAAEVRSLIETDSDVRIIYQTARGLEGLIRNA
TH_0581|M.thermoresistible__bu AKDIPLSGITDPNHERYKEAAEVRGLIESDPDVRRIYETALGLEGLVRNA
Mflv_3636|M.gilvum_PYR-GCK AKDIPVSGITDPTHERYKEAAEVRALIDTDPDVRTIYETARGLEGLVRNA
Mvan_2777|M.vanbaalenii_PYR-1 AKDIPVSGITDPTHERYKEAAEVRALIDTDPDVRTIYETARGLEGLVRNA
MSMEG_3178|M.smegmatis_MC2_155 AKDIPLSGITDPNHERYKEAAEVRGLIDTDPDVRTIYETARGLEGLVRNA
MAB_2696c|M.abscessus_ATCC_199 AKDIPVWGITNPEHERYKEAAEVRTLIDTDPDVRNIYQTALGLEGLIRNA
*****: ***:* ***:******* **::*.*** **:** *****:***
MUL_1545|M.ulcerans_Agy99 GVHACAVIMSSEPLTEAIPLWKRPQDGAIITGWDYPSCEAIGLLKMDFLG
MMAR_2369|M.marinum_M GVHACAVIMSSEPLTEAIPLWKRPQDGAIITGWDYPSCEAIGLLKMDFLG
MAV_3224|M.avium_104 GVHACAVIMSSEPLTEAIPLWKRPQDGAIITGWDYPSCEAIGLLKMDFLG
Mb1574|M.bovis_AF2122/97 GVHACAVIMSSEPLTEAIPLWKRPQDGAIITGWDYPACEAIGLLKMDFLG
Rv1547|M.tuberculosis_H37Rv GVHACAVIMSSEPLTEAIPLWKRPQDGAIITGWDYPACEAIGLLKMDFLG
MLBr_01207|M.leprae_Br4923 GVHACAVILSSEPLTEAIPLWKRPQDGAIITGWDYPACEAIGLLKMDFLG
TH_0581|M.thermoresistible__bu GVHACAVIMSSEPLIDAIPLWKRPQDGAIITGWDYPACEAIGLLKMDFLG
Mflv_3636|M.gilvum_PYR-GCK GVHACAVIMSSEPLIDAIPLWKRPQDGAVITGWDYPSCEAIGLLKMDFLG
Mvan_2777|M.vanbaalenii_PYR-1 GVHACAVIMSSEPLIDAIPLWKRPQDGAVITGWDYPSCEAIGLLKMDFLG
MSMEG_3178|M.smegmatis_MC2_155 GVHACAVIMSSEPLIDAIPLWKRPQDGAIITGWDYPSCEAIGLLKMDFLG
MAB_2696c|M.abscessus_ATCC_199 GVHACAVIMSSEPLTDAIPLWKRAQDGAIITGWDYPSCEAIGLLKMDFLG
********:***** :*******.****:*******:*************
MUL_1545|M.ulcerans_Agy99 LRNLTIIGDAIENIEANRGIDLDLESLPLDDKPTYELLGRGETLGVFQLD
MMAR_2369|M.marinum_M LRNLTIIGDAIENIKANRGIDLDLESLPLDDKPTYELLGRGETLGVFQLD
MAV_3224|M.avium_104 LRNLTIIGDALDNIKANRGIDLDLESVPLDDKATYELLGRGDTLGVFQLD
Mb1574|M.bovis_AF2122/97 LRNLTIIGDAIDNVRANRGIDLDLESVPLDDKATYELLGRGDTLGVFQLD
Rv1547|M.tuberculosis_H37Rv LRNLTIIGDAIDNVRANRGIDLDLESVPLDDKATYELLGRGDTLGVFQLD
MLBr_01207|M.leprae_Br4923 LRNLTIIGDAIENIKTNRGIDLDLESVPLDDQATYELLGRGDTLGVFQLD
TH_0581|M.thermoresistible__bu LRNLTIIGDALENIKANRGIDLDLDTIPMDDPATYELLGRGDTLGVFQLD
Mflv_3636|M.gilvum_PYR-GCK LRNLTIIGDCIENIKANRGVDVDLESLALDDPKAYELLGRGDTLGVFQLD
Mvan_2777|M.vanbaalenii_PYR-1 LRNLTIIGDCIENIKANRGIDVDLESLTLDDPKAYELLGRGDTLGVFQLD
MSMEG_3178|M.smegmatis_MC2_155 LRNLTIIGDAIANIKANRGIDLDLETLPLDDPAAYELLSRGDTLGVFQLD
MAB_2696c|M.abscessus_ATCC_199 LRNLTVIGDALDNIKANRGIDLDLDHLPLDDPATYELLSRGDTLGVFQLD
*****:***.: *:.:***:*:**: :.:** :****.**:********
MUL_1545|M.ulcerans_Agy99 GGPMRDLLRRMQPTEFNDIVAVLALYRPGPMGMNAHNDYADRKNNRQAVK
MMAR_2369|M.marinum_M GGPMRDLLRRMQPTEFNDIVAVLALYRPGPMGMNAHNDYADRKNNRQAVK
MAV_3224|M.avium_104 GGPMRDLLRRMQPTEFNDIVAVLALYRPGPMGMNAHNDYADRKNGRQPIK
Mb1574|M.bovis_AF2122/97 GGPMRDLLRRMQPTGFEDVVAVIALYRPGPMGMNAHNDYADRKNNRQAIK
Rv1547|M.tuberculosis_H37Rv GGPMRDLLRRMQPTGFEDVVAVIALYRPGPMGMNAHNDYADRKNNRQAIK
MLBr_01207|M.leprae_Br4923 GGPMRDLLRRMQPTGFEDIVAVLALYRPGPMGMNAHNDYADRKNNRQVIK
TH_0581|M.thermoresistible__bu GGPMRDLLRRMQPTSFDDIVAVLALYRPGPMGMNAHNDYADRKNGRQPIT
Mflv_3636|M.gilvum_PYR-GCK GSAMRDLLRRMQPTEFNDIVAVLALYRPGPMGMNAHNDYADRKNGRQPIK
Mvan_2777|M.vanbaalenii_PYR-1 GGPMRDLLRRMQPTEFNDIVAVLALYRPGPMGMNAHNDYADRKNGRQAIK
MSMEG_3178|M.smegmatis_MC2_155 GGPMRDLLRRMQPTGFNDIVAVLALYRPGPMGMNAHNDYADRKNGRQPIK
MAB_2696c|M.abscessus_ATCC_199 GGPMRDLLRRMQPTGFNDIVAVLALYRPGPMGMNAHNDYADRKNGRQPIK
*..*********** *:*:***:*********************.** :.
MUL_1545|M.ulcerans_Agy99 PIHPELEEPLREILSETYGLIVYQEQIMFIAQKVASYTMGKADALRKAMG
MMAR_2369|M.marinum_M PIHPELEEPLREILSETYGLIVYQEQIMFIAQKVASYTMGKADALRKAMG
MAV_3224|M.avium_104 PIHPELEEPLREILAETYGLIVYQEQIMFIAQKVASYTMGKADALRKAMG
Mb1574|M.bovis_AF2122/97 PIHPELEEPLREILAETYGLIVYQEQIMRIAQKVASYSLARADILRKAMG
Rv1547|M.tuberculosis_H37Rv PIHPELEEPLREILAETYGLIVYQEQIMRIAQKVASYSLARADILRKAMG
MLBr_01207|M.leprae_Br4923 PIHPELEEPLREILAETYGLIVYQEQIMRIAQKVAGYSLARADILRKAMG
TH_0581|M.thermoresistible__bu PIHPELAEPLEEILAETYGLIVYQEQIMRIAQKVAGYSLARADILRKAMG
Mflv_3636|M.gilvum_PYR-GCK PIHPELEEPLKDILAETYGLIVYQEQIMFIAQKVASYSMGKADALRKAMG
Mvan_2777|M.vanbaalenii_PYR-1 PIHPELEEPLKDILSETYGLIVYQEQIMFIAQKVASYSMGKADALRKAMG
MSMEG_3178|M.smegmatis_MC2_155 PIHPELEEPLKDILAETYGLIVYQEQIMFIAQKVASYTMGKADALRKAMG
MAB_2696c|M.abscessus_ATCC_199 PIHPELEEPLKDILAETFGLIVYQEQIMFIAQKVASYSMGKADALRKAMG
****** ***.:**:**:********** ******.*::.:** ******
MUL_1545|M.ulcerans_Agy99 KKKLEVLEAEYKGFYEGMTANGFSEKAVKALWDTILPFAGYAFNKSHAAG
MMAR_2369|M.marinum_M KKKLEVLEAEYKGFYEGMTANGFSEKAVKALWDTILPFAGYAFNKSHAAG
MAV_3224|M.avium_104 KKKLEVLEAEYKGFYEGMTANGFSEKAVKALWDTILPFAGYAFNKSHAAG
Mb1574|M.bovis_AF2122/97 KKKREVLEKEFEGFSDGMQANGFSPAAIKALWDTILPFADYAFNKSHAAG
Rv1547|M.tuberculosis_H37Rv KKKREVLEKEFEGFSDGMQANGFSPAAIKALWDTILPFADYAFNKSHAAG
MLBr_01207|M.leprae_Br4923 KKKREVLEKEFEGFSEGMQANGFSVHAIKALWDIILPFADYAFNKSHAAG
TH_0581|M.thermoresistible__bu KKKREVLDKEYEGFSEGMKANGFSASAIKALWDTVLPFADYAFNKSHAAG
Mflv_3636|M.gilvum_PYR-GCK KKKLEVLEAEYKGFKEGMTANGFSEGAVKALWDTILPFAGYAFNKSHAAG
Mvan_2777|M.vanbaalenii_PYR-1 KKKLEVLEAEYQGFKEGMTANGFSEKAVKALWDTILPFAGYAFNKSHAAG
MSMEG_3178|M.smegmatis_MC2_155 KKKLEVLEAEYKGFKEGMTANGFSEGAVKALWDTILPFAGYAFNKSHAAG
MAB_2696c|M.abscessus_ATCC_199 KKKLEVLEAEYKGFYEGMTNNGFSEKAVKALWDTILPFAGYAFNKSHAAG
*** ***: *::** :** **** *:***** :****.**********
MUL_1545|M.ulcerans_Agy99 YGLVSYWTAYLKANYPAEYMAGLLTSVGDDKDKAAVYLADCRKLGITVLP
MMAR_2369|M.marinum_M YGLVSYWTAYLKANYPAEYMAGLLTSVGDDKDKAAVYLADCRKLGITVLP
MAV_3224|M.avium_104 YGLVSYWTAYLKANYPAEYMAGLLTSVGDDKDKAAVYLADCRKLGITVLP
Mb1574|M.bovis_AF2122/97 YGMVSYWTAYLKANYPAEYMAGLLTSVGDDKDKAAVYLADCRKLGITVLP
Rv1547|M.tuberculosis_H37Rv YGMVSYWTAYLKANYPAEYMAGLLTSVGDDKDKAAVYLADCRKLGITVLP
MLBr_01207|M.leprae_Br4923 YGLISYWTAYLKANFAGEYMAGLLTSVGDDKDKAAVYLADCRKFGITVLP
TH_0581|M.thermoresistible__bu YGLVSYWTAYLKANYPAEYMAGLLTSVRDDKDKAAVYLADCRRLGITVLP
Mflv_3636|M.gilvum_PYR-GCK YGLVSYWTAYLKANYQAEYMAGLLTSVGDDKDKAAIYLADCRRLGITVLP
Mvan_2777|M.vanbaalenii_PYR-1 YGLVSYWTAYLKANYPAEYMAGLLTSVGDDKDKAAVYLADCRRLGITVLP
MSMEG_3178|M.smegmatis_MC2_155 YGLVSYWTAYLKANYPAEYMAGLLTSVGDDKDKAAVYLADCRRLGITVLP
MAB_2696c|M.abscessus_ATCC_199 YGLVSFWTAYLKANYPAEYMAGLLTSVGDDKDKAAVYLADCRRLGITVLP
**::*:********: .********** *******:******::******
MUL_1545|M.ulcerans_Agy99 PDVNESLVNFASVGQDIRFGLGAVRNVGANVVGSLIGTRSGKGKFTDFSD
MMAR_2369|M.marinum_M PDVNESLVNFASVGQDIRFGLGAVRNVGANVVGSLIGTRSGKGKFTDFSD
MAV_3224|M.avium_104 PDVNESLVNFASVGQDIRFGLGAVRNVGANVVGSLIKTREEKGKFTDFSD
Mb1574|M.bovis_AF2122/97 PDVNESGLNFASVGQDIRYGLGAVRNVGANVVGSLLQTRNDKGKFTDFSD
Rv1547|M.tuberculosis_H37Rv PDVNESGLNFASVGQDIRYGLGAVRNVGANVVGSLLQTRNDKGKFTDFSD
MLBr_01207|M.leprae_Br4923 PDVNESVLDFASVGADIRYGLGAVRNVGANVVGSLIKTRNAKGKFADFSD
TH_0581|M.thermoresistible__bu PDVNESAVNFTSVGKDIRYGLGAVRNVGANVVSSLIATRTEKGKFTDFSD
Mflv_3636|M.gilvum_PYR-GCK PDVNESVQNFASVGDDIRFGLGAVRNVGANVVASLVSTREEKGKYTDFSD
Mvan_2777|M.vanbaalenii_PYR-1 PDVNESVQNFASVGDDIRFGLGAVRNVGANVVSSLVATRKEKGKFADFSD
MSMEG_3178|M.smegmatis_MC2_155 PDVNESEHNFASVGDDIRFGLGAIRNVGANVVSSLIKTRTEKGKFTDFSD
MAB_2696c|M.abscessus_ATCC_199 PDVNESVHNFASVGEDIRYGLGGVRNVGANVVQSLIATREEKGAFTDFSD
****** :*:*** ***:***.:******** **: ** ** ::****
MUL_1545|M.ulcerans_Agy99 YLNKIDISACNKKVTESLIKAGAFDSLGHPRKGLFLVHTDAVDSVLGTKK
MMAR_2369|M.marinum_M YLNKIDISACNKKVTESLIKAGAFDSLGHPRKGLFLVHTDAVDSVLGTKK
MAV_3224|M.avium_104 YLNKIDISACNKKVTESLIKAGAFDSLKHARKGLFLVHTDAVDSVLGTKK
Mb1574|M.bovis_AF2122/97 YLNKIDISACNKKVTESLIKAGAFDSLGHARKGLFLVHSDAVDSVLGTKK
Rv1547|M.tuberculosis_H37Rv YLNKIDISACNKKVTESLIKAGAFDSLGHARKGLFLVHSDAVDSVLGTKK
MLBr_01207|M.leprae_Br4923 YLNKIDITSCNKKVTESLIKAGAFDSLGHSRKGLFLVHADAVDSVLGTKK
TH_0581|M.thermoresistible__bu YLNKIDISVCNKKVTESLIKAGAFDSLGHPRKGLFLVHGDAVESVLGTKK
Mflv_3636|M.gilvum_PYR-GCK YLNKIDITACTKKVTESLIKAGAFDSLGHPRKGLFLVHTDAVDSVLGTKK
Mvan_2777|M.vanbaalenii_PYR-1 YLNKIDIAACNKKVTESLVKAGAFDSLGHPRKGLFLVHTDAVDSVLGTKK
MSMEG_3178|M.smegmatis_MC2_155 YLNKIDITACNKKVTESLIKAGAFDSLGHPRKGLFLVHTDAVDSVLGTKK
MAB_2696c|M.abscessus_ATCC_199 YLHKIDIAACNKKVTESLVKAGAFDSLGHPRKGLFLVQSDAVDSVLGTKK
**:****: *.*******:******** *.*******: ***:*******
MUL_1545|M.ulcerans_Agy99 AEAMGQFDLFGG-SDSGA---DAVFTIKVPEDEWEDKHKLALEREMLGLY
MMAR_2369|M.marinum_M AEAMGQFDLFGG-SDSGA---DAVFTIKVPEDEWEDKHKLALEREMLGLY
MAV_3224|M.avium_104 AEAMGQFDLFGG-DGGCT---ESVFTIKVPDDEWEDKHKLALEREMLGLY
Mb1574|M.bovis_AF2122/97 AEALGQFDLFGS-NDDGTGTADPVFTIKVPDDEWEDKHKLALEREMLGLY
Rv1547|M.tuberculosis_H37Rv AEALGQFDLFGS-NDDGTGTADPVFTIKVPDDEWEDKHKLALEREMLGLY
MLBr_01207|M.leprae_Br4923 AEAIGQFDLFGG-TDGGT---DAVFTIKVPDDEWEDKHKLALEREMLGLY
TH_0581|M.thermoresistible__bu AEAMGQFDLFGG-DGSSEDSLDSVFTIKVPDEEWDDKHKLALEREMLGLY
Mflv_3636|M.gilvum_PYR-GCK AEAMGQFDLFGGGDDDG-DTGDSAFTIKVPDEEWEDKHKLALEREMLGLY
Mvan_2777|M.vanbaalenii_PYR-1 AEAMGQFDLFGGADGSGADAGDSAFTIKVPDEEWEDKHKLALEREMLGLY
MSMEG_3178|M.smegmatis_MC2_155 AEAMGQFDLFGGGEDTG---TDAVFTIKVPDEEWEDKHKLALEREMLGLY
MAB_2696c|M.abscessus_ATCC_199 AEAMGQFDLFGGGGEDS-VPASDIFAIKVPDDEWEEKHKLALEREMLGLY
***:*******. . *:****::**::**************
MUL_1545|M.ulcerans_Agy99 VSGHPLNGVAHLLATQVDTAIPAILDGDVSNDAQVRVGGILAAVNRRVNK
MMAR_2369|M.marinum_M VSGHPLNGVAHLLAAQVDTAIPAILDGDVSNDAQVRVGGILAAVNRRVNK
MAV_3224|M.avium_104 VSGHPLNGVAHLLAAQVDTQIPAILDGDVPNETQVRVGGILASVNRRVNK
Mb1574|M.bovis_AF2122/97 VSGHPLNGVAHLLAAQVDTAIPAILDGDVPNDAQVRVGGILASVNRRVNK
Rv1547|M.tuberculosis_H37Rv VSGHPLNGVAHLLAAQVDTAIPAILDGDVPNDAQVRVGGILASVNRRVNK
MLBr_01207|M.leprae_Br4923 VSGHPLNGVAHLLAAQVDTAIPTILDGGVSNDTQVRVGGILAAVNRRVNK
TH_0581|M.thermoresistible__bu VSGHPLEGVAHLLANQVDTQIPAILDGEVPNDAQVTVGGILNSVNRRVNK
Mflv_3636|M.gilvum_PYR-GCK VSGHPLNGIAHLLTAQVDTQIPAILEGAIPNDAQVRVGGILASVNRRVNK
Mvan_2777|M.vanbaalenii_PYR-1 VSGHPLNGVAHLLAAQVDTQIPAILDGDVANDTQVRVGGILASVNRRVNK
MSMEG_3178|M.smegmatis_MC2_155 VSGHPLNGVAHLLANQVDTQIPAILDGDVANDAQVLVGGILASVNRRVNK
MAB_2696c|M.abscessus_ATCC_199 VSGHPLNGVAHLLSRQTDTQIPAILDGEVANDAVVKVGGILASVNRRVNK
******:*:****: *.** **:**:* :.*:: * ***** :*******
MUL_1545|M.ulcerans_Agy99 NGMPWASAQLEDLTGGIEVMFFPHTYSNYGADIADDAVVLVNAKVAIRDD
MMAR_2369|M.marinum_M NGMPWASAQLEDLTGGIEVMFFPHTYSNYGADIADDAVVLVNAKVAIRDD
MAV_3224|M.avium_104 NGMPWASAQLEDLTGGIEVMFFPHAYSTYGADIADDAVVLINAKVAIRDD
Mb1574|M.bovis_AF2122/97 NGMPWASAQLEDLTGGIEVMFFPHTYSSYGADIVDDAVVLVNAKVAVRDD
Rv1547|M.tuberculosis_H37Rv NGMPWASAQLEDLTGGIEVMFFPHTYSSYGADIVDDAVVLVNAKVAVRDD
MLBr_01207|M.leprae_Br4923 NGIPWASAQLDDLTGGIEVMFFPHTYSSYGADIIDDAVVLVNAKVVVRDD
TH_0581|M.thermoresistible__bu NGLPWASAQLEDLTGGIEVLFFPQTYSLYGAEIADDAVVLIKAKVAARDD
Mflv_3636|M.gilvum_PYR-GCK NGLPWASAQIEDLSGGIEVLFFPQTYSMFGAEIADDVVVLVGAKVAKRDD
Mvan_2777|M.vanbaalenii_PYR-1 NGLPWASAQIEDLTGGIEVLFFPQTYSMFGAEIADDVVVLVGAKVAIRDD
MSMEG_3178|M.smegmatis_MC2_155 NGLPWASAQLEDLTGGIEVLFFPQTYSLFGADIADDVVVLVKAKVAARDD
MAB_2696c|M.abscessus_ATCC_199 NGMPWASAQLEDLTGGIEVLFFPQAYSVYGADIADDAVVLVNAKVAIRDD
**:******::**:*****:***::** :**:* **.***: ***. ***
MUL_1545|M.ulcerans_Agy99 RISLIANELVVPDFSNAQADRPLAVSLPTRQCTIDKVTALKQVLARHPGT
MMAR_2369|M.marinum_M RISLIANELVVPDFSNAQADRPLAVSLPTRQCTIDKVTALKQVLARHPGT
MAV_3224|M.avium_104 RIALIANELVVPDFSIAQVDRPLAVSLPTRQCTIDKVTALKQVLARHPGT
Mb1574|M.bovis_AF2122/97 RIALIANDLTVPDFSNAEVERPLAVSLPTRQCTFDKVSALKQVLARHPGT
Rv1547|M.tuberculosis_H37Rv RIALIANDLTVPDFSNAEVERPLAVSLPTRQCTFDKVSALKQVLARHPGT
MLBr_01207|M.leprae_Br4923 RIALIANQLVVPDFSNVQEDRPLAVSLLTRQCTFDKVNALKQVLARHPGT
TH_0581|M.thermoresistible__bu RIALIAHELIVPDFSNASADRPIAVSLPTRQCTLDKVTALKQVLTNHPGT
Mflv_3636|M.gilvum_PYR-GCK RISLIANELIVPDFTSAQVNRPVAVSLPTRQCTVDKVTALKQVLARHPGT
Mvan_2777|M.vanbaalenii_PYR-1 RISLIANELVVPDFSSANVNRPVAVSLPTRQCTVDKVTALKQVLARHPGT
MSMEG_3178|M.smegmatis_MC2_155 RIALIAHELIVPDFSSAQADRPLSVSLPTRQCTIDKVTALKQVLANHPGT
MAB_2696c|M.abscessus_ATCC_199 RVSLIANDLVVPDFSQAADDRPVAVTMPTRQCTIDKVTALKQVLTRHPGT
*::***::* ****: . :**::*:: *****.***.******:.****
MUL_1545|M.ulcerans_Agy99 SQVHLRLISGDRITTLELDQSLRVTPSPALMGDLKELLGPGCLGS
MMAR_2369|M.marinum_M SQVHLRLISGDRITTLELDQSLRVTPSPALMGDLKELLGPGCLGS
MAV_3224|M.avium_104 SQVHLRLISGDRITTLELDASLRVTPSPALMGDLKELLGPGCLGG
Mb1574|M.bovis_AF2122/97 SQVHLRLISGDRITTLALDQSLRVTPSPALMGDLKELLGPGCLGS
Rv1547|M.tuberculosis_H37Rv SQVHLRLISGDRITTLALDQSLRVTPSPALMGDLKELLGPGCLGS
MLBr_01207|M.leprae_Br4923 SQVHLRLISGDRITTLELDQSLRVTSSPALMGDLKALLGPGCLGD
TH_0581|M.thermoresistible__bu AQVHLRLINGDRITTLELDPSLRVTPSLELMGDLKALLGPGCLG-
Mflv_3636|M.gilvum_PYR-GCK AQVHLRLISGERITTLELDQSLRVTPSSALMGDLKELLGPGCLGG
Mvan_2777|M.vanbaalenii_PYR-1 AQVHLRLISGERITTLELDQSLRVTPSSALMGDLKELLGPGCLGG
MSMEG_3178|M.smegmatis_MC2_155 SQVHLRLISGERITTLELDQSLRVTPSSALMGDLKALLGPGCLG-
MAB_2696c|M.abscessus_ATCC_199 NQVHLRLISGERVTTLELDQSLRVTPSSALMGDLKALLGPGCLGG
*******.*:*:*** ** *****.* ****** ********