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M. ulcerans Agy99 MUL_1214 (-)

annotation: transmembrane protein
coordinates: 1306492 - 1307442
length: 316

VVPAVMAYPWHSRRDYWLIGIAAFVVIVLFAWWRGLYLTTILHRRVAMMRRRPAEPGAEADTSTTVTLRI
GPPASDIDVLPLPVIARYLNCYGIRVDAIRITGRTTGSGETQTWIGLTVSAATNLAALQARAARIPLHET
ARVTARRLADHLREIGWEVSLVAAEDLPSLLDPDSDHALRETWRGVQHGDSEYLAAYRVIVDAALPDTLA
EIWSHPALETWMAIEIAARGRAGADYSVAAACAFRTDEQPAVAAPLATLIPQRGNHGPTLAAMELSSTRA
LDGYADAPENLLMRLVWFTPGAGLHRAAPTETASRT
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. ulcerans Agy99MUL_1214--100% (316)transmembrane protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0300-1e-10259.81% (316) transmembrane protein
M. gilvum PYR-GCKMflv_0319-4e-5544.52% (283) putative transmembrane protein
M. tuberculosis H37RvRv0292-1e-10259.49% (316) transmembrane protein
M. leprae Br4923MLBr_02527-3e-9658.10% (315) hypothetical protein MLBr_02527
M. abscessus ATCC 19977MAB_2224c-7e-4640.00% (280) hypothetical protein MAB_2224c
M. marinum MMMAR_0551-0.099.37% (316) transmembrane protein
M. avium 104MAV_4860-5e-9357.86% (318) hypothetical protein MAV_4860
M. smegmatis MC2 155MSMEG_0626-2e-6247.90% (286) hypothetical protein MSMEG_0626
M. thermoresistible (build 8)TH_4663-1e-1940.30% (134) PUTATIVE putative regulatory protein, LuxR
M. vanbaalenii PYR-1Mvan_0422-6e-5544.01% (284) putative transmembrane protein

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_0319|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0422|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0626|M.smegmatis_MC2_155      --------------------------------------------------
MUL_1214|M.ulcerans_Agy99           --------------------------------------------------
MMAR_0551|M.marinum_M               --------------------------------------------------
Mb0300|M.bovis_AF2122/97            --------------------------------------------------
Rv0292|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02527|M.leprae_Br4923          --------------------------------------------------
MAV_4860|M.avium_104                --------------------------------------------------
MAB_2224c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4663|M.thermoresistible__bu      VLVGPAGAGKTELARTVLQHRRREQPHTVLHWVAGTASASRIPFGAFSHL
                                                                                      

Mflv_0319|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0422|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0626|M.smegmatis_MC2_155      --------------------------------------------------
MUL_1214|M.ulcerans_Agy99           --------------------------------------------------
MMAR_0551|M.marinum_M               --------------------------------------------------
Mb0300|M.bovis_AF2122/97            --------------------------------------------------
Rv0292|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02527|M.leprae_Br4923          --------------------------------------------------
MAV_4860|M.avium_104                --------------------------------------------------
MAB_2224c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4663|M.thermoresistible__bu      VETGGGGEPATVLRTARESLCGPVLRDRTRTGLLLIVDDAHHLDTLSATL
                                                                                      

Mflv_0319|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0422|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0626|M.smegmatis_MC2_155      --------------------------------------------------
MUL_1214|M.ulcerans_Agy99           --------------------------------------------------
MMAR_0551|M.marinum_M               --------------------------------------------------
Mb0300|M.bovis_AF2122/97            --------------------------------------------------
Rv0292|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02527|M.leprae_Br4923          --------------------------------------------------
MAV_4860|M.avium_104                --------------------------------------------------
MAB_2224c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4663|M.thermoresistible__bu      VHQVAVSTPASLLLTVRDGEPVPDAITALWKDDLLARIDIEPFSQAECER
                                                                                      

Mflv_0319|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0422|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0626|M.smegmatis_MC2_155      --------------------------------------------------
MUL_1214|M.ulcerans_Agy99           --------------------------------------------------
MMAR_0551|M.marinum_M               --------------------------------------------------
Mb0300|M.bovis_AF2122/97            --------------------------------------------------
Rv0292|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02527|M.leprae_Br4923          --------------------------------------------------
MAV_4860|M.avium_104                --------------------------------------------------
MAB_2224c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4663|M.thermoresistible__bu      LLADALGGRVESASAERLYAISEGNPLYLRHLVTGTVASGALREVEGIWQ
                                                                                      

Mflv_0319|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0422|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0626|M.smegmatis_MC2_155      --------------------------------------------------
MUL_1214|M.ulcerans_Agy99           --------------------------------------------------
MMAR_0551|M.marinum_M               --------------------------------------------------
Mb0300|M.bovis_AF2122/97            --------------------------------------------------
Rv0292|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02527|M.leprae_Br4923          --------------------------------------------------
MAV_4860|M.avium_104                --------------------------------------------------
MAB_2224c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4663|M.thermoresistible__bu      LRGEVALTPQLSTLIDQHLSALPDQIRTVLAYLAIEEPLTVADLSDLVSP
                                                                                      

Mflv_0319|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0422|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0626|M.smegmatis_MC2_155      --------------------------------------------------
MUL_1214|M.ulcerans_Agy99           --------------------------------------------------
MMAR_0551|M.marinum_M               --------------------------------------------------
Mb0300|M.bovis_AF2122/97            --------------------------------------------------
Rv0292|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02527|M.leprae_Br4923          ------------------------------------------------MS
MAV_4860|M.avium_104                --------------------------------------------------
MAB_2224c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4663|M.thermoresistible__bu      EAVEAAEAAGAVTVDERGADLIVHPAHPLYTETVRAGLGRLTRRSLRTAL
                                                                                      

Mflv_0319|M.gilvum_PYR-GCK          -----------MIVRLTLAALFV---------------------------
Mvan_0422|M.vanbaalenii_PYR-1       -----------MTVRLTLAALFV---------------------------
MSMEG_0626|M.smegmatis_MC2_155      -----------MTARIALASLFV---------------------------
MUL_1214|M.ulcerans_Agy99           ----------------------M---------------------------
MMAR_0551|M.marinum_M               -MSFDRSIPRPGSGRITLALLAV---------------------------
Mb0300|M.bovis_AF2122/97            ---MNPIPSWPGRGRVTLVLLAV---------------------------
Rv0292|M.tuberculosis_H37Rv         ---MNPIPSWPGRGRVTLVLLAV---------------------------
MLBr_02527|M.leprae_Br4923          AHRSRPAAMWPGSSRITLALLAV---------------------------
MAV_4860|M.avium_104                --MSKHRIPRPGSGRITLALLAV---------------------------
MAB_2224c|M.abscessus_ATCC_199      ---------MPGTLRLTLIATLV---------------------------
TH_4663|M.thermoresistible__bu      VARWSRRPPDNVSDRLRLAALAVNSQTPPPATDLIATSWEAMQLGDLLLG
                                                          :                           

Mflv_0319|M.gilvum_PYR-GCK          -----------------IPAAMAYPWQ-----------------------
Mvan_0422|M.vanbaalenii_PYR-1       -----------------IPAVMTYPWQ-----------------------
MSMEG_0626|M.smegmatis_MC2_155      -----------------VAAVLAQPWQ-----------------------
MUL_1214|M.ulcerans_Agy99           -----------------VPAVMAYPWH-----------------------
MMAR_0551|M.marinum_M               -----------------VPAVMAYPWH-----------------------
Mb0300|M.bovis_AF2122/97            -----------------VPVALAYPWQ-----------------------
Rv0292|M.tuberculosis_H37Rv         -----------------VPVALAYPWQ-----------------------
MLBr_02527|M.leprae_Br4923          -----------------MPALMAYPWW-----------------------
MAV_4860|M.avium_104                -----------------VPAAMAYPWH-----------------------
MAB_2224c|M.abscessus_ATCC_199      -----------------AAGAFALYRR-----------------------
TH_4663|M.thermoresistible__bu      EQLARGALGQSDTLAARLPLAHALAWQGRGREADDVLAAVDPDRLTEFDI
                                                      .   :                           

Mflv_0319|M.gilvum_PYR-GCK          -------TTFDRWLLGVAVAVVVILFAWWR---------------GLFVT
Mvan_0422|M.vanbaalenii_PYR-1       -------TVAQRWLLGVAIAVVVVLFASWR---------------GRFVT
MSMEG_0626|M.smegmatis_MC2_155      -------TTTQRWVLGVSIAAVIVLLAWWK---------------GMFLT
MUL_1214|M.ulcerans_Agy99           -------SRRDYWLIGIAAFVVIVLFAWWR---------------GLYLT
MMAR_0551|M.marinum_M               -------SRRDYWLIGIAAFVVIVLFAWWR---------------GLYLT
Mb0300|M.bovis_AF2122/97            -------STRDYVLLGVAAAVVIGLFGFWR---------------GLYFT
Rv0292|M.tuberculosis_H37Rv         -------STRDYVLLGVAAAVVIGLFGFWR---------------GLYFT
MLBr_02527|M.leprae_Br4923          -------FTRSYWLLGIVALVVVVLFGWWR---------------GLYLT
MAV_4860|M.avium_104                -------SPRDYWLLGIAAAVLIVLFGWWG---------------GLYFT
MAB_2224c|M.abscessus_ATCC_199      -------DPADRWIAITAGVLALVLLVWWR---------------GTFLT
TH_4663|M.thermoresistible__bu      MAWTLPKAANQFWMLSESAEAIALLDRMRTRLHQPAAVTAFDALAATFAM
                                              .  :          *                    . :  

Mflv_0319|M.gilvum_PYR-GCK          TLVARRIRLLTRRGRSADDGDAGEF--------ATVALRVE---QGQADL
Mvan_0422|M.vanbaalenii_PYR-1       AIFGRRTAILLRRGRIRDAAPSGEY--------ATVALRLEP--REAAEL
MSMEG_0626|M.smegmatis_MC2_155      TRIG-RALAMVRRNRAEDTVETDAHR-------ATVVLRVDP--AAPAQL
MUL_1214|M.ulcerans_Agy99           TILHRRVAMMRRRPA-EPGAEADTS--------TTVTLRIGPPASDIDVL
MMAR_0551|M.marinum_M               TILHRRVAMMRRRPA-EPGAEADTS--------TTVTLRIGPPASDIDVL
Mb0300|M.bovis_AF2122/97            TIARRGLAILRRRRR-IAEPATCTR--------TTVLVWVGPPASDTNVL
Rv0292|M.tuberculosis_H37Rv         TIARRGLAILRRRRR-IAEPATCTR--------TTVLVWVGPPASDTNVL
MLBr_02527|M.leprae_Br4923          TILRRRLAMMWRRGRPVSASGSATR--------TTVLLRLGPPVGGSDVI
MAV_4860|M.avium_104                TLLRRRLAIIGRHNA-VRPQRPDPA--------TTVLIRVGAPADGSDAL
MAB_2224c|M.abscessus_ATCC_199      DILGRLTKMLARRVSGRAPADAAPVVAVGVDARSTVVLELTAS-PSGEDV
TH_4663|M.thermoresistible__bu      NAGQPRTALELAGRVLQTPESQDLAVAWAAATATLSSARMARFDEVETHA
                                                                     :     :          

Mflv_0319|M.gilvum_PYR-GCK          PLALAADHLDRYGIAFDKVRVTSREA-AG---------------------
Mvan_0422|M.vanbaalenii_PYR-1       PLSLVAGYLDRYGISFDKVRVTSRIAGPG---------------------
MSMEG_0626|M.smegmatis_MC2_155      P--VVVGYLDRYGITCDKVRITHRDA-GG---------------------
MUL_1214|M.ulcerans_Agy99           PLPVIARYLNCYGIRVDAIRITGRTTGSG---------------------
MMAR_0551|M.marinum_M               PLPVIARYLNCYGIRVDAIRITGRTTGSG---------------------
Mb0300|M.bovis_AF2122/97            PLTLIARYLDRYGIRADTIRITSRVTASG---------------------
Rv0292|M.tuberculosis_H37Rv         PLTLIARYLDRYGIRADTIRITSRVTASG---------------------
MLBr_02527|M.leprae_Br4923          PLPLITRYLNCYGIRADSIRITSRNNESDGA-------------------
MAV_4860|M.avium_104                PLPLIAGYLDRYGIRADKVRITSRDNASDES-------------------
MAB_2224c|M.abscessus_ATCC_199      PVGLLAGYLDRYGVRCSSIRITTTDVDGA---------------------
TH_4663|M.thermoresistible__bu      ARGLAAQHPGLLRFTIGLGQITRLILAGXLTRADFLAHHYLSFCEFQQPG
                                    .  : . : .   .  .  ::*                            

Mflv_0319|M.gilvum_PYR-GCK          ----------------HRTTWVSLTLGAASNIAALTARSPQIPLQDTVEV
Mvan_0422|M.vanbaalenii_PYR-1       ----------------AAATWVALTLGAADNIAALSARSPAIPLRDTAEL
MSMEG_0626|M.smegmatis_MC2_155      ----------------TRRSWISLTVDAVDNLAALQARSARIPLQDTTEV
MUL_1214|M.ulcerans_Agy99           ----------------ETQTWIGLTVSAATNLAALQARAARIPLHETARV
MMAR_0551|M.marinum_M               ----------------ETQTWIGLTVSAATNLAALQARAARIPLHETARV
Mb0300|M.bovis_AF2122/97            ----------------DCRTWVGLTVVADDNLAALQARSARIPLQETAQV
Rv0292|M.tuberculosis_H37Rv         ----------------DCRTWVGLTVVADDNLAALQARSARIPLQETAQV
MLBr_02527|M.leprae_Br4923          ----------------LCETWIGLTVSAAKNLAALQARSSRIPLQETAQV
MAV_4860|M.avium_104                ----------------RRQTWIGLTVSAPDNLAALQARSPRIPLAETAQV
MAB_2224c|M.abscessus_ATCC_199      ----------------ASRTWVSLTLSAADNLTALQARSARIPLRETADT
TH_4663|M.thermoresistible__bu      RAIGEVLLAHILIARGDLPTATTLLRQAAAALSSTGYSWGPLALMQLTQV
                                                       :   *   *   :::       :.* : .  

Mflv_0319|M.gilvum_PYR-GCK          AARR-----LADHLRERGWEVTIDD-APGPLPGDGGK-----ETWRGVVD
Mvan_0422|M.vanbaalenii_PYR-1       AGRR-----LADQLREAGWEVSVDDTAAGPLSG-EAK-----ERWRGVED
MSMEG_0626|M.smegmatis_MC2_155      VGRR-----LADHLREQGWTVTVVEGVDTPLPV-SGK-----ETWRGVAD
MUL_1214|M.ulcerans_Agy99           TARR-----LADHLREIGWEVSLVAAEDLPSLLDPDSDHALRETWRGVQH
MMAR_0551|M.marinum_M               TARR-----LADHLREIGWEVSLVAAEDLPSLLDPDSDHALRETWRGVQH
Mb0300|M.bovis_AF2122/97            AARR-----LADHLREIGWEAGTAAPDEIPALVAADS----RETWRGMRH
Rv0292|M.tuberculosis_H37Rv         AARR-----LADHLREIGWEAGTAAPDEIPALVAADS----RETWRGMRH
MLBr_02527|M.leprae_Br4923          AARR-----LADHLREIGWEVSLAVPDGIPRLITAAG----DETWRGMQQ
MAV_4860|M.avium_104                AARR-----LADHLRETGWEAGVVPPDDVPRLLTSNP----RERWRGVQR
MAB_2224c|M.abscessus_ATCC_199      VARR-----LADHLRELGWHVTATEAPEEPLSPEAKE------GSRGMSD
TH_4663|M.thermoresistible__bu      LGARGDADGASEALRRAEHSHGTRSELYAPELALXXX------XWRGLRD
                                     . *      :: **.             *               **:  

Mflv_0319|M.gilvum_PYR-GCK          -GHGHLAAYRVRVDERLTETLAAAGSAGT-EFWSAVEFTGSRTSP---EI
Mvan_0422|M.vanbaalenii_PYR-1       -GRGFLAAYRIAADEPLDGLFSAVRALDADEIWTAVEFTGDRTQP---EF
MSMEG_0626|M.smegmatis_MC2_155      -DAGVVAAYRVKVDDRLDEVLAEIGHLPAEETWTALEFTGSPAEP---LL
MUL_1214|M.ulcerans_Agy99           GDSEYLAAYRVIVDAALPDTLAEIWSHPALETWMAIEIAARGRAGADYSV
MMAR_0551|M.marinum_M               GDSEYLAAYRVIVDAALPDTLAEIWSHPALETWMAIEIAARGRSGADYSV
Mb0300|M.bovis_AF2122/97            TDSDYVAAYRVSADAELPDTLPAIRSRPAQETWIALEIAYAAGSSTRYTV
Rv0292|M.tuberculosis_H37Rv         TDSDYVAAYRVSANAELPDTLPAIRSRPAQETWIALEIAYAAGSSTRYTV
MLBr_02527|M.leprae_Br4923          -GSDYLTAYRVNVDDELPGTLDAVRLYPARETWTALEIACPDSSSNRNTI
MAV_4860|M.avium_104                GPSDYLAAYQIPVDESLPETLEAIRSYPARESCVALEIAGDKAAP---TI
MAB_2224c|M.abscessus_ATCC_199      -DHGYLAAYRVAVNNDLSETLDNVGDAGLPERWTALELTGTTDAP---RL
TH_4663|M.thermoresistible__bu      -ESGHLAAYRITVDDRLPETLADLWDGSAAEVWTAIEFSGTTAHP---MI
                                         ::**:: .:  *   :         *   *:*::          .

Mflv_0319|M.gilvum_PYR-GCK          AASCALRTTDRP---PAIAGLTAERGLHRSALDALGPTSHRRLLAPPVPA
Mvan_0422|M.vanbaalenii_PYR-1       AAACALRTAQRPGVRASLPGLTPQHGRHAAALAAMAPGSDQRLPGP----
MSMEG_0626|M.smegmatis_MC2_155      TVCAAVRTSDRPAAKAPLAGLTPARGRHRPALAALNPLSTERLDGTAVPL
MUL_1214|M.ulcerans_Agy99           AAACAFRTDEQPAVAAPLATLIPQRGNHGPTLAAMELSSTRALDGYADAP
MMAR_0551|M.marinum_M               AAACAFRTDEQPAVAAPLATLIPQRGNHGPTLAAMELSSTRALDGYADAP
Mb0300|M.bovis_AF2122/97            AAACALRTDWRPGGTAPVAGLLPQHGNHVPALTALDPRSTRRLDGHTDAP
Rv0292|M.tuberculosis_H37Rv         AAACALRTDWRPGGTAPVAGLLPQHGNHVPALTALDPRSTRRLDGHTDAP
MLBr_02527|M.leprae_Br4923          AAACAFLTDTAPQGAAPLAGLTPQHGNHRPALAVLDLFSAQRLDGHTDTD
MAV_4860|M.avium_104                AVACAFQTDTAPDRGAPLAGLIPQRGNHLPALTALDLLSTGRLDGHTAAP
MAB_2224c|M.abscessus_ATCC_199      TVVCALRTQDKPAAHAPLAGLTPCWGEHLLVLRSLNPLSSKTLAGAGAAV
TH_4663|M.thermoresistible__bu      TAGCALRSEKKPEAAGPLPALTPQRGLHRPALEALAPTSGRRLPGEPVPL
                                    :. .*. :   *    .:. * .  * *  .*  :   *   * .     

Mflv_0319|M.gilvum_PYR-GCK          TPELVAQLRLPVGAILSRT----------------------
Mvan_0422|M.vanbaalenii_PYR-1       -----TGLMPPV---LSRT----------------------
MSMEG_0626|M.smegmatis_MC2_155      PAVVRTSVKGSVEHEAAQEAGHPA-----------------
MUL_1214|M.ulcerans_Agy99           ENLLMRLVWFTPGAGLHRAAPTETASRT-------------
MMAR_0551|M.marinum_M               ENLLMRLVWSTPGAGLHRAAPTETASRT-------------
Mb0300|M.bovis_AF2122/97            ADLLTRLHWPTPTAGAHRAPLTNAVSRT-------------
Rv0292|M.tuberculosis_H37Rv         ADLLTRLHWPTPTAGAHRAPLTNAVSRT-------------
MLBr_02527|M.leprae_Br4923          ADLLTRLRWPAPAAGVSSCTATRSPAVSA------------
MAV_4860|M.avium_104                ADLLDRLHWPTQGAPAGDADTVAAART--------------
MAB_2224c|M.abscessus_ATCC_199      TAEFLDGLTQRDQEPALV-----------------------
TH_4663|M.thermoresistible__bu      PDGLLDSLFWPVRGVRSTARQRRTARQVETESVDTAPVSRT