For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
SAHRSRPAAMWPGSSRITLALLAVMPALMAYPWWFTRSYWLLGIVALVVVVLFGWWRGLYLTTILRRRLA MMWRRGRPVSASGSATRTTVLLRLGPPVGGSDVIPLPLITRYLNCYGIRADSIRITSRNNESDGALCETW IGLTVSAAKNLAALQARSSRIPLQETAQVAARRLADHLREIGWEVSLAVPDGIPRLITAAGDETWRGMQQ GSDYLTAYRVNVDDELPGTLDAVRLYPARETWTALEIACPDSSSNRNTIAAACAFLTDTAPQGAAPLAGL TPQHGNHRPALAVLDLFSAQRLDGHTDTDADLLTRLRWPAPAAGVSSCTATRSPAVSA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. leprae Br4923 | MLBr_02527 | - | - | 100% (339) | hypothetical protein MLBr_02527 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0300 | - | 1e-109 | 61.86% (333) | transmembrane protein |
| M. gilvum PYR-GCK | Mflv_0319 | - | 7e-59 | 45.13% (308) | putative transmembrane protein |
| M. tuberculosis H37Rv | Rv0292 | - | 1e-109 | 61.56% (333) | transmembrane protein |
| M. abscessus ATCC 19977 | MAB_2224c | - | 3e-51 | 42.52% (301) | hypothetical protein MAB_2224c |
| M. marinum M | MMAR_0551 | - | 1e-102 | 59.00% (339) | transmembrane protein |
| M. avium 104 | MAV_4860 | - | 1e-108 | 62.58% (326) | hypothetical protein MAV_4860 |
| M. smegmatis MC2 155 | MSMEG_0626 | - | 1e-63 | 45.70% (291) | hypothetical protein MSMEG_0626 |
| M. thermoresistible (build 8) | TH_4663 | - | 3e-18 | 41.67% (132) | PUTATIVE putative regulatory protein, LuxR |
| M. ulcerans Agy99 | MUL_1214 | - | 7e-96 | 58.10% (315) | transmembrane protein |
| M. vanbaalenii PYR-1 | Mvan_0422 | - | 4e-63 | 46.33% (300) | putative transmembrane protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0319|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0422|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0626|M.smegmatis_MC2_155 --------------------------------------------------
Mb0300|M.bovis_AF2122/97 --------------------------------------------------
Rv0292|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_02527|M.leprae_Br4923 --------------------------------------------------
MAV_4860|M.avium_104 --------------------------------------------------
MMAR_0551|M.marinum_M --------------------------------------------------
MUL_1214|M.ulcerans_Agy99 --------------------------------------------------
MAB_2224c|M.abscessus_ATCC_199 --------------------------------------------------
TH_4663|M.thermoresistible__bu VLVGPAGAGKTELARTVLQHRRREQPHTVLHWVAGTASASRIPFGAFSHL
Mflv_0319|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0422|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0626|M.smegmatis_MC2_155 --------------------------------------------------
Mb0300|M.bovis_AF2122/97 --------------------------------------------------
Rv0292|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_02527|M.leprae_Br4923 --------------------------------------------------
MAV_4860|M.avium_104 --------------------------------------------------
MMAR_0551|M.marinum_M --------------------------------------------------
MUL_1214|M.ulcerans_Agy99 --------------------------------------------------
MAB_2224c|M.abscessus_ATCC_199 --------------------------------------------------
TH_4663|M.thermoresistible__bu VETGGGGEPATVLRTARESLCGPVLRDRTRTGLLLIVDDAHHLDTLSATL
Mflv_0319|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0422|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0626|M.smegmatis_MC2_155 --------------------------------------------------
Mb0300|M.bovis_AF2122/97 --------------------------------------------------
Rv0292|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_02527|M.leprae_Br4923 --------------------------------------------------
MAV_4860|M.avium_104 --------------------------------------------------
MMAR_0551|M.marinum_M --------------------------------------------------
MUL_1214|M.ulcerans_Agy99 --------------------------------------------------
MAB_2224c|M.abscessus_ATCC_199 --------------------------------------------------
TH_4663|M.thermoresistible__bu VHQVAVSTPASLLLTVRDGEPVPDAITALWKDDLLARIDIEPFSQAECER
Mflv_0319|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0422|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0626|M.smegmatis_MC2_155 --------------------------------------------------
Mb0300|M.bovis_AF2122/97 --------------------------------------------------
Rv0292|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_02527|M.leprae_Br4923 --------------------------------------------------
MAV_4860|M.avium_104 --------------------------------------------------
MMAR_0551|M.marinum_M --------------------------------------------------
MUL_1214|M.ulcerans_Agy99 --------------------------------------------------
MAB_2224c|M.abscessus_ATCC_199 --------------------------------------------------
TH_4663|M.thermoresistible__bu LLADALGGRVESASAERLYAISEGNPLYLRHLVTGTVASGALREVEGIWQ
Mflv_0319|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0422|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0626|M.smegmatis_MC2_155 --------------------------------------------------
Mb0300|M.bovis_AF2122/97 --------------------------------------------------
Rv0292|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_02527|M.leprae_Br4923 --------------------------------------------------
MAV_4860|M.avium_104 --------------------------------------------------
MMAR_0551|M.marinum_M --------------------------------------------------
MUL_1214|M.ulcerans_Agy99 --------------------------------------------------
MAB_2224c|M.abscessus_ATCC_199 --------------------------------------------------
TH_4663|M.thermoresistible__bu LRGEVALTPQLSTLIDQHLSALPDQIRTVLAYLAIEEPLTVADLSDLVSP
Mflv_0319|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0422|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0626|M.smegmatis_MC2_155 --------------------------------------------------
Mb0300|M.bovis_AF2122/97 --------------------------------------------------
Rv0292|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_02527|M.leprae_Br4923 ------------------------------------------------MS
MAV_4860|M.avium_104 --------------------------------------------------
MMAR_0551|M.marinum_M --------------------------------------------------
MUL_1214|M.ulcerans_Agy99 --------------------------------------------------
MAB_2224c|M.abscessus_ATCC_199 --------------------------------------------------
TH_4663|M.thermoresistible__bu EAVEAAEAAGAVTVDERGADLIVHPAHPLYTETVRAGLGRLTRRSLRTAL
Mflv_0319|M.gilvum_PYR-GCK -----------MIVRLTLAALFV---------------------------
Mvan_0422|M.vanbaalenii_PYR-1 -----------MTVRLTLAALFV---------------------------
MSMEG_0626|M.smegmatis_MC2_155 -----------MTARIALASLFV---------------------------
Mb0300|M.bovis_AF2122/97 ---MNPIPSWPGRGRVTLVLLAV---------------------------
Rv0292|M.tuberculosis_H37Rv ---MNPIPSWPGRGRVTLVLLAV---------------------------
MLBr_02527|M.leprae_Br4923 AHRSRPAAMWPGSSRITLALLAV---------------------------
MAV_4860|M.avium_104 --MSKHRIPRPGSGRITLALLAV---------------------------
MMAR_0551|M.marinum_M -MSFDRSIPRPGSGRITLALLAV---------------------------
MUL_1214|M.ulcerans_Agy99 ----------------------M---------------------------
MAB_2224c|M.abscessus_ATCC_199 ---------MPGTLRLTLIATLV---------------------------
TH_4663|M.thermoresistible__bu VARWSRRPPDNVSDRLRLAALAVNSQTPPPATDLIATSWEAMQLGDLLLG
:
Mflv_0319|M.gilvum_PYR-GCK -----------------IPAAMAYPWQ-----------------------
Mvan_0422|M.vanbaalenii_PYR-1 -----------------IPAVMTYPWQ-----------------------
MSMEG_0626|M.smegmatis_MC2_155 -----------------VAAVLAQPWQ-----------------------
Mb0300|M.bovis_AF2122/97 -----------------VPVALAYPWQ-----------------------
Rv0292|M.tuberculosis_H37Rv -----------------VPVALAYPWQ-----------------------
MLBr_02527|M.leprae_Br4923 -----------------MPALMAYPWW-----------------------
MAV_4860|M.avium_104 -----------------VPAAMAYPWH-----------------------
MMAR_0551|M.marinum_M -----------------VPAVMAYPWH-----------------------
MUL_1214|M.ulcerans_Agy99 -----------------VPAVMAYPWH-----------------------
MAB_2224c|M.abscessus_ATCC_199 -----------------AAGAFALYRR-----------------------
TH_4663|M.thermoresistible__bu EQLARGALGQSDTLAARLPLAHALAWQGRGREADDVLAAVDPDRLTEFDI
. :
Mflv_0319|M.gilvum_PYR-GCK -------TTFDRWLLGVAVAVVVILFAWWR---------------GLFVT
Mvan_0422|M.vanbaalenii_PYR-1 -------TVAQRWLLGVAIAVVVVLFASWR---------------GRFVT
MSMEG_0626|M.smegmatis_MC2_155 -------TTTQRWVLGVSIAAVIVLLAWWK---------------GMFLT
Mb0300|M.bovis_AF2122/97 -------STRDYVLLGVAAAVVIGLFGFWR---------------GLYFT
Rv0292|M.tuberculosis_H37Rv -------STRDYVLLGVAAAVVIGLFGFWR---------------GLYFT
MLBr_02527|M.leprae_Br4923 -------FTRSYWLLGIVALVVVVLFGWWR---------------GLYLT
MAV_4860|M.avium_104 -------SPRDYWLLGIAAAVLIVLFGWWG---------------GLYFT
MMAR_0551|M.marinum_M -------SRRDYWLIGIAAFVVIVLFAWWR---------------GLYLT
MUL_1214|M.ulcerans_Agy99 -------SRRDYWLIGIAAFVVIVLFAWWR---------------GLYLT
MAB_2224c|M.abscessus_ATCC_199 -------DPADRWIAITAGVLALVLLVWWR---------------GTFLT
TH_4663|M.thermoresistible__bu MAWTLPKAANQFWMLSESAEAIALLDRMRTRLHQPAAVTAFDALAATFAM
. : * . :
Mflv_0319|M.gilvum_PYR-GCK TLVARRIRLLTRRGRSADDGDAGEF--------ATVALRVE---QGQADL
Mvan_0422|M.vanbaalenii_PYR-1 AIFGRRTAILLRRGRIRDAAPSGEY--------ATVALRLEP--REAAEL
MSMEG_0626|M.smegmatis_MC2_155 TRIG-RALAMVRRNRAEDTVETDAHR-------ATVVLRVDP--AAPAQL
Mb0300|M.bovis_AF2122/97 TIARRGLAILRRRRR-IAEPATCTR--------TTVLVWVGPPASDTNVL
Rv0292|M.tuberculosis_H37Rv TIARRGLAILRRRRR-IAEPATCTR--------TTVLVWVGPPASDTNVL
MLBr_02527|M.leprae_Br4923 TILRRRLAMMWRRGRPVSASGSATR--------TTVLLRLGPPVGGSDVI
MAV_4860|M.avium_104 TLLRRRLAIIGRHNA-VRPQRPDPA--------TTVLIRVGAPADGSDAL
MMAR_0551|M.marinum_M TILHRRVAMMRRRPA-EPGAEADTS--------TTVTLRIGPPASDIDVL
MUL_1214|M.ulcerans_Agy99 TILHRRVAMMRRRPA-EPGAEADTS--------TTVTLRIGPPASDIDVL
MAB_2224c|M.abscessus_ATCC_199 DILGRLTKMLARRVSGRAPADAAPVVAVGVDARSTVVLELTAS-PSGEDV
TH_4663|M.thermoresistible__bu NAGQPRTALELAGRVLQTPESQDLAVAWAAATATLSSARMARFDEVETHA
: :
Mflv_0319|M.gilvum_PYR-GCK PLALAADHLDRYGIAFDKVRVTSREA-AG---------------------
Mvan_0422|M.vanbaalenii_PYR-1 PLSLVAGYLDRYGISFDKVRVTSRIAGPG---------------------
MSMEG_0626|M.smegmatis_MC2_155 P--VVVGYLDRYGITCDKVRITHRDA-GG---------------------
Mb0300|M.bovis_AF2122/97 PLTLIARYLDRYGIRADTIRITSRVTASG---------------------
Rv0292|M.tuberculosis_H37Rv PLTLIARYLDRYGIRADTIRITSRVTASG---------------------
MLBr_02527|M.leprae_Br4923 PLPLITRYLNCYGIRADSIRITSRNNESDGA-------------------
MAV_4860|M.avium_104 PLPLIAGYLDRYGIRADKVRITSRDNASDES-------------------
MMAR_0551|M.marinum_M PLPVIARYLNCYGIRVDAIRITGRTTGSG---------------------
MUL_1214|M.ulcerans_Agy99 PLPVIARYLNCYGIRVDAIRITGRTTGSG---------------------
MAB_2224c|M.abscessus_ATCC_199 PVGLLAGYLDRYGVRCSSIRITTTDVDGA---------------------
TH_4663|M.thermoresistible__bu ARGLAAQHPGLLRFTIGLGQITRLILAGXLTRADFLAHHYLSFCEFQQPG
. : . : . . . ::*
Mflv_0319|M.gilvum_PYR-GCK ----------------HRTTWVSLTLGAASNIAALTARSPQIPLQDTVEV
Mvan_0422|M.vanbaalenii_PYR-1 ----------------AAATWVALTLGAADNIAALSARSPAIPLRDTAEL
MSMEG_0626|M.smegmatis_MC2_155 ----------------TRRSWISLTVDAVDNLAALQARSARIPLQDTTEV
Mb0300|M.bovis_AF2122/97 ----------------DCRTWVGLTVVADDNLAALQARSARIPLQETAQV
Rv0292|M.tuberculosis_H37Rv ----------------DCRTWVGLTVVADDNLAALQARSARIPLQETAQV
MLBr_02527|M.leprae_Br4923 ----------------LCETWIGLTVSAAKNLAALQARSSRIPLQETAQV
MAV_4860|M.avium_104 ----------------RRQTWIGLTVSAPDNLAALQARSPRIPLAETAQV
MMAR_0551|M.marinum_M ----------------ETQTWIGLTVSAATNLAALQARAARIPLHETARV
MUL_1214|M.ulcerans_Agy99 ----------------ETQTWIGLTVSAATNLAALQARAARIPLHETARV
MAB_2224c|M.abscessus_ATCC_199 ----------------ASRTWVSLTLSAADNLTALQARSARIPLRETADT
TH_4663|M.thermoresistible__bu RAIGEVLLAHILIARGDLPTATTLLRQAAAALSSTGYSWGPLALMQLTQV
: * * ::: :.* : .
Mflv_0319|M.gilvum_PYR-GCK AARR-----LADHLRERGWEVTIDD-APGPLPGDGGK-----ETWRGVVD
Mvan_0422|M.vanbaalenii_PYR-1 AGRR-----LADQLREAGWEVSVDDTAAGPLSG-EAK-----ERWRGVED
MSMEG_0626|M.smegmatis_MC2_155 VGRR-----LADHLREQGWTVTVVEGVDTPLPV-SGK-----ETWRGVAD
Mb0300|M.bovis_AF2122/97 AARR-----LADHLREIGWEAGTAAPDEIPALVAADS----RETWRGMRH
Rv0292|M.tuberculosis_H37Rv AARR-----LADHLREIGWEAGTAAPDEIPALVAADS----RETWRGMRH
MLBr_02527|M.leprae_Br4923 AARR-----LADHLREIGWEVSLAVPDGIPRLITAAG----DETWRGMQQ
MAV_4860|M.avium_104 AARR-----LADHLRETGWEAGVVPPDDVPRLLTSNP----RERWRGVQR
MMAR_0551|M.marinum_M TARR-----LADHLREIGWEVSLVAAEDLPSLLDPDSDHALRETWRGVQH
MUL_1214|M.ulcerans_Agy99 TARR-----LADHLREIGWEVSLVAAEDLPSLLDPDSDHALRETWRGVQH
MAB_2224c|M.abscessus_ATCC_199 VARR-----LADHLRELGWHVTATEAPEEPLSPEAKE------GSRGMSD
TH_4663|M.thermoresistible__bu LGARGDADGASEALRRAEHSHGTRSELYAPELALXXX------XWRGLRD
. * :: **. * **:
Mflv_0319|M.gilvum_PYR-GCK -GHGHLAAYRVRVDERLTETLAAAGSAGT-EFWSAVEFTGSRTSP---EI
Mvan_0422|M.vanbaalenii_PYR-1 -GRGFLAAYRIAADEPLDGLFSAVRALDADEIWTAVEFTGDRTQP---EF
MSMEG_0626|M.smegmatis_MC2_155 -DAGVVAAYRVKVDDRLDEVLAEIGHLPAEETWTALEFTGSPAEP---LL
Mb0300|M.bovis_AF2122/97 TDSDYVAAYRVSADAELPDTLPAIRSRPAQETWIALEIAYAAGSSTRYTV
Rv0292|M.tuberculosis_H37Rv TDSDYVAAYRVSANAELPDTLPAIRSRPAQETWIALEIAYAAGSSTRYTV
MLBr_02527|M.leprae_Br4923 -GSDYLTAYRVNVDDELPGTLDAVRLYPARETWTALEIACPDSSSNRNTI
MAV_4860|M.avium_104 GPSDYLAAYQIPVDESLPETLEAIRSYPARESCVALEIAGDKAAP---TI
MMAR_0551|M.marinum_M GDSEYLAAYRVIVDAALPDTLAEIWSHPALETWMAIEIAARGRSGADYSV
MUL_1214|M.ulcerans_Agy99 GDSEYLAAYRVIVDAALPDTLAEIWSHPALETWMAIEIAARGRAGADYSV
MAB_2224c|M.abscessus_ATCC_199 -DHGYLAAYRVAVNNDLSETLDNVGDAGLPERWTALELTGTTDAP---RL
TH_4663|M.thermoresistible__bu -ESGHLAAYRITVDDRLPETLADLWDGSAAEVWTAIEFSGTTAHP---MI
::**:: .: * : * *:*:: .
Mflv_0319|M.gilvum_PYR-GCK AASCALRTTDRP---PAIAGLTAERGLHRSALDALGPTSHRRLLAPPVPA
Mvan_0422|M.vanbaalenii_PYR-1 AAACALRTAQRPGVRASLPGLTPQHGRHAAALAAMAPGSDQRLPGP----
MSMEG_0626|M.smegmatis_MC2_155 TVCAAVRTSDRPAAKAPLAGLTPARGRHRPALAALNPLSTERLDGTAVPL
Mb0300|M.bovis_AF2122/97 AAACALRTDWRPGGTAPVAGLLPQHGNHVPALTALDPRSTRRLDGHTDAP
Rv0292|M.tuberculosis_H37Rv AAACALRTDWRPGGTAPVAGLLPQHGNHVPALTALDPRSTRRLDGHTDAP
MLBr_02527|M.leprae_Br4923 AAACAFLTDTAPQGAAPLAGLTPQHGNHRPALAVLDLFSAQRLDGHTDTD
MAV_4860|M.avium_104 AVACAFQTDTAPDRGAPLAGLIPQRGNHLPALTALDLLSTGRLDGHTAAP
MMAR_0551|M.marinum_M AAACAFRTDEQPAVAAPLATLIPQRGNHGPTLAAMELSSTRALDGYADAP
MUL_1214|M.ulcerans_Agy99 AAACAFRTDEQPAVAAPLATLIPQRGNHGPTLAAMELSSTRALDGYADAP
MAB_2224c|M.abscessus_ATCC_199 TVVCALRTQDKPAAHAPLAGLTPCWGEHLLVLRSLNPLSSKTLAGAGAAV
TH_4663|M.thermoresistible__bu TAGCALRSEKKPEAAGPLPALTPQRGLHRPALEALAPTSGRRLPGEPVPL
:. .*. : * .:. * . * * .* : * * .
Mflv_0319|M.gilvum_PYR-GCK TPELVAQLRLPVGAILSRT----------------------
Mvan_0422|M.vanbaalenii_PYR-1 -----TGLMPPV---LSRT----------------------
MSMEG_0626|M.smegmatis_MC2_155 PAVVRTSVKGSVEHEAAQEAGHPA-----------------
Mb0300|M.bovis_AF2122/97 ADLLTRLHWPTPTAGAHRAPLTNAVSRT-------------
Rv0292|M.tuberculosis_H37Rv ADLLTRLHWPTPTAGAHRAPLTNAVSRT-------------
MLBr_02527|M.leprae_Br4923 ADLLTRLRWPAPAAGVSSCTATRSPAVSA------------
MAV_4860|M.avium_104 ADLLDRLHWPTQGAPAGDADTVAAART--------------
MMAR_0551|M.marinum_M ENLLMRLVWSTPGAGLHRAAPTETASRT-------------
MUL_1214|M.ulcerans_Agy99 ENLLMRLVWFTPGAGLHRAAPTETASRT-------------
MAB_2224c|M.abscessus_ATCC_199 TAEFLDGLTQRDQEPALV-----------------------
TH_4663|M.thermoresistible__bu PDGLLDSLFWPVRGVRSTARQRRTARQVETESVDTAPVSRT