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VYPIRPPVDDGQTVMVTDGQQVGGTRSFLPPVEGMRACAAMGVVVTHVAFQTGHSSGVAGRLFGRFDLAV AVFFALSGFLLWRGHAAAARGGSPRPRTGHYLRSRAVRIMPAYVVAVVVILSLLPDSDHASLTVWLANLT LTQIYVPLTLTGGLTQMWSLSVEVGFYLALPLLAFLARRVPVGARVPVIAAAAALSLAWAWLPVAAGSGM NPLNWPPAFFSWFAAGMLLAEWVHSPIGLIHRLARHRVLIGVVAMLAYLVAASPLAGPAGLVQGSATQFA VKTAMGAVVAFALVAPLVLDGPGTPHRLLGSTTMVTLGRWSYGLFIWHLAALDMVFPVIGTFAFTGRMPT VLVLTLIFGFAIAAVSYALVESPCREALRRWEKRTEHSAGPDIDREADAIAP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_1127 | - | - | 100% (402) | integral membrane acyltransferase |
| M. ulcerans Agy99 | MUL_4492 | - | 3e-43 | 34.94% (352) | integral membrane acyltransferase |
| M. ulcerans Agy99 | MUL_4810 | - | 2e-16 | 27.00% (400) | transmembrane acyltransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0233 | - | 0.0 | 81.25% (400) | integral membrane acyltransferase |
| M. gilvum PYR-GCK | Mflv_0420 | - | 1e-151 | 73.50% (366) | acyltransferase 3 |
| M. tuberculosis H37Rv | Rv0228 | - | 0.0 | 81.25% (400) | integral membrane acyltransferase |
| M. leprae Br4923 | MLBr_02580 | - | 1e-167 | 77.23% (382) | putative acyltransferase |
| M. abscessus ATCC 19977 | MAB_4473c | - | 1e-139 | 67.59% (361) | acyltransferase |
| M. marinum M | MMAR_0477 | - | 0.0 | 99.23% (388) | integral membrane acyltransferase |
| M. avium 104 | MAV_4941 | - | 0.0 | 82.19% (393) | acyltransferase |
| M. smegmatis MC2 155 | MSMEG_0319 | - | 1e-159 | 75.47% (371) | acyltransferase |
| M. thermoresistible (build 8) | TH_4330 | - | 1e-149 | 69.19% (383) | PUTATIVE acyltransferase 3 |
| M. vanbaalenii PYR-1 | Mvan_0251 | - | 1e-152 | 73.12% (372) | acyltransferase 3 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0420|M.gilvum_PYR-GCK ---------MSATGTASSRGDVG-----ASGDGVGGTRSFLPAVEGLRAW
Mvan_0251|M.vanbaalenii_PYR-1 ---------MTVTAAP------------ADPSVVGGTRGFLPAVEGLRAC
MSMEG_0319|M.smegmatis_MC2_155 ---------MTTEQSA------------QAEHEVGGTRGFLPAVEGMRAC
TH_4330|M.thermoresistible__bu MPGTLVAMAVTAEQVAGNPGDSSGASPRDLSHEVSGTRSFLPAVEGLRAC
MUL_1127|M.ulcerans_Agy99 ------------MYPIRPPVDDGQTVMVTDGQQVGGTRSFLPPVEGMRAC
MMAR_0477|M.marinum_M --------------------------MVTDGQQVGGTRSFLPPVEGMRAC
MAV_4941|M.avium_104 -------------------------MVVSDDQRVGGVRSFLPAVEGMRAC
Mb0233|M.bovis_AF2122/97 -----MGPADESGAPIRPQTPHRHTVLVTNGQVVGGTRGFLPAVEGMRAC
Rv0228|M.tuberculosis_H37Rv -----MGPADESGAPIRPQTPHRHTVLVTNGQVVGGTRGFLPAVEGMRAC
MLBr_02580|M.leprae_Br4923 ---------------------------MTDVQQVGGIRSFLPAVEGMRAC
MAB_4473c|M.abscessus_ATCC_199 ------------------------MSAAPASAPAVHARGFVPALEGMRAC
. *.*:*.:**:**
Mflv_0420|M.gilvum_PYR-GCK AAIGVVITHVAFQTGQSGGAVGRILGRFDLAVAVFFALSGFLLWRGHAAA
Mvan_0251|M.vanbaalenii_PYR-1 AAIGVVVTHVAFQTGQSGGVVGRVLGRFDLAVAVFFALSGFLLWRGHAAA
MSMEG_0319|M.smegmatis_MC2_155 AAMGVVLTHVAFQTGHTGGISGRIFGRFDLAVAVFFALSGFLLWRGHAAA
TH_4330|M.thermoresistible__bu AALGVIVTHVAFQTGHTSGAVGRLLGRFDLAVAVFFALSGFLLWRGHAAA
MUL_1127|M.ulcerans_Agy99 AAMGVVVTHVAFQTGHSSGVAGRLFGRFDLAVAVFFALSGFLLWRGHAAA
MMAR_0477|M.marinum_M AAMGVVVTHVAFQTGHSSGVAGRLFGRFDLAVAVFFALSGFLLWRGHAAA
MAV_4941|M.avium_104 AAMGVVVTHVAFQTGHSSGVDGRLFGRFDLAVAVFFALSGFLLWRGHAAA
Mb0233|M.bovis_AF2122/97 AAVGVVVTHVAFQTGHSSGVGGRLFGRFDLAVAVFFAVSGFLLWRGHAAA
Rv0228|M.tuberculosis_H37Rv AAVGVVVTHVAFQTGHSSGVGGRLFGRFDLAVAVFFAVSGFLLWRGHAAA
MLBr_02580|M.leprae_Br4923 AAIGVVVTHVAFQTGHSSGIVGRLFGRFDLAVAVFFALSGFLLWRGHAAT
MAB_4473c|M.abscessus_ATCC_199 AAMGVVVTHTAFQTGHTGGVDGRILGRFDLAVAVFFALSGFLLWRPHALA
**:**::**.*****::.* **::************:******* ** :
Mflv_0420|M.gilvum_PYR-GCK ARGLRS---RPSTGHYLRSRIVRIMPGYLVAVVVILTLLPEAK-ADVTVW
Mvan_0251|M.vanbaalenii_PYR-1 ARGLRS---RPTTGHYLRSRVVRIMPGYLVAVVVIMTLLPDVN-ADFTVW
MSMEG_0319|M.smegmatis_MC2_155 ARGLRP---RPRTGHYLRSRIVRIMPGYVVAVIVILLLLPEAK-ADLTVW
TH_4330|M.thermoresistible__bu VRGLRP---TPATGRYLRSRVVRIMPGYLVAVVVILLLLPGAT-ADLTVW
MUL_1127|M.ulcerans_Agy99 ARGGSP---RPRTGHYLRSRAVRIMPAYVVAVVVILSLLPDSDHASLTVW
MMAR_0477|M.marinum_M ARGGSP---RPRTGHYLRSRAVRIMPAYVVAVVVILSLLPDSDHASLTVW
MAV_4941|M.avium_104 ARDLAP---RPRTGHYLRSRVVRIMPAYLVAVVVILTLLPDADHPSPTVW
Mb0233|M.bovis_AF2122/97 ARDLR---SHPRTGPYLRSRVARIMPAYVVAVVVILSLLPDADHASLTVW
Rv0228|M.tuberculosis_H37Rv ARDLR---SHPRTGPYLRSRVARIMPAYVVAVVVILSLLPDADHASLTVW
MLBr_02580|M.leprae_Br4923 ARQPVPKDEQPHTSHYLRSRVVRIMPAYLVAVVVILSLLPGANHASWIVW
MAB_4473c|M.abscessus_ATCC_199 AGGGAR---PAPTGRYFASRFVRIVPAYLAAVFIVLLLLPDAAGARGIVW
. . *. *: ** .**:*.*:.**.::: *** . **
Mflv_0420|M.gilvum_PYR-GCK LANLTLTQIYVPLTLTAGLTQMWSLSVEMSFYLALPLLALLARRVPVRAR
Mvan_0251|M.vanbaalenii_PYR-1 LANLTLTQIYVPLTLTSGLTQMWSLSVEMSFYLALPLLALLARRLPVRAR
MSMEG_0319|M.smegmatis_MC2_155 LANLTLTQIYVPLTLTAGLTQMWSLSVEVSFYLALPLLALLARRLPVRAR
TH_4330|M.thermoresistible__bu LANLTLTQIYVPLTLTSGLTQMWSLSVEMTFYLVLPLLALLARQVPVRAR
MUL_1127|M.ulcerans_Agy99 LANLTLTQIYVPLTLTGGLTQMWSLSVEVGFYLALPLLAFLARRVPVGAR
MMAR_0477|M.marinum_M LANLTLTQIYVPLTLTGGLTQMWSLSVEVGFYLALPLLAFLARRVPVGAR
MAV_4941|M.avium_104 LANLTLTQIYVPLTLTGGLTQMWSLSVEVGFYLALPVLALLARRLPVTAR
Mb0233|M.bovis_AF2122/97 LANLTLTQIYVPLTLTGGLTQMWSLSVEVAFYAALPVLALLGRRIPVGAR
Rv0228|M.tuberculosis_H37Rv LANLTLTQIYVPLTLTGGLTQMWSLSVEVAFYAALPVLALLGRRIPVGAR
MLBr_02580|M.leprae_Br4923 LANLTLTQIYVPLTLTSGLTQMWSLSVEASFYLALPILALLTRRISVRAR
MAB_4473c|M.abscessus_ATCC_199 LANLTLTQLYIPLTLTAGLTQMWSLAVEVAFYIALPAIALLMRRAPVGWR
********:*:*****.********:** ** .** :*:* *: .* *
Mflv_0420|M.gilvum_PYR-GCK IPVLIGAAAASLLWVHIPFDGASGHNLWNWPPAFFSWFAAGMVLAELTVS
Mvan_0251|M.vanbaalenii_PYR-1 IPAIVVVAAASLFWVRIPFDPDSGHNLWNWPPAFFSWFAAGMVLAELTVG
MSMEG_0319|M.smegmatis_MC2_155 IGVITAVAALSLLWVCIPFAGDTGHNPWNWPPAFFSWFAAGMVLAELTVS
TH_4330|M.thermoresistible__bu IPVLLATAVLSLFWVRIPFGPDSGLNPWNWPPAFFSWFAAGMILAELTVT
MUL_1127|M.ulcerans_Agy99 VPVIAAAAALSLAWAWLPVAAGSGMNPLNWPPAFFSWFAAGMLLAEWVHS
MMAR_0477|M.marinum_M VPVIAAAAALSLAWAWLPVAAGSGMNPLNWPPAFFSWFAAGMLLAEWVHS
MAV_4941|M.avium_104 VPAIAALGALSWAWGWVPVHPGSGLNPLNWPPAFFSWFAAGMLLAEWVHG
Mb0233|M.bovis_AF2122/97 VPAIAALAALSWAWGWLPLDAGSGINPLTWPPAFFSWFAAGMLLAEWAYS
Rv0228|M.tuberculosis_H37Rv VPAIAALAALSWAWGWLPLDAGSGINPLTWPPAFFSWFAAGMLLAEWAYS
MLBr_02580|M.leprae_Br4923 VPVIAAAVVISWAWGWVPVHTGSGVNPLTWPPAFFSWFAAGMLLAEWSYS
MAB_4473c|M.abscessus_ATCC_199 APLLTAAGAASLGWSFIPFHPPAGINPLTWPPAFFSWFVAGMLLAEWSAA
: . * * :*. :* * .*********.***:***
Mflv_0420|M.gilvum_PYR-GCK PVGWAHRLARRR---VLMALLALTAFLIAASPLAGREGLHPGSIAQVTLK
Mvan_0251|M.vanbaalenii_PYR-1 PVGWAHRLARRR---VLMAVLAVTAFLIAASPLAGREGLHPGSVGQVTLK
MSMEG_0319|M.smegmatis_MC2_155 PYGRVHRLARRR---VLMAAIAVVAFAIAASPLAGKEGLHPGSVGQVMLK
TH_4330|M.thermoresistible__bu RVGWFHRLARRR---VLMGMFALAAFLVAASPLVGLEGLAPGSIVQVTLK
MUL_1127|M.ulcerans_Agy99 PIGLIHRLARHR---VLIGVVAMLAYLVAASPLAGPAGLVQGSATQFAVK
MMAR_0477|M.marinum_M PIGLVHRLARHR---VLIGVVAMLAYLVAASPLAGPAGLVQGSATQFAVK
MAV_4941|M.avium_104 GIGRPVRLAQSRTGRVLLAVVAVAAYLVAASPLAGPEGLVPGTPAQFAVK
Mb0233|M.bovis_AF2122/97 PVGLPHRWARRR---VAMAVTALLGYLVAASPLAGPEGLVPGTAAQFAVK
Rv0228|M.tuberculosis_H37Rv PVGLPHRWARRR---VAMAVTALLGYLVAASPLAGPEGLVPGTAAQFAVK
MLBr_02580|M.leprae_Br4923 RISLPHRLARSR---LTMAVMTLLAYLVAVSPLAGPEGLVPGTATQFAVK
MAB_4473c|M.abscessus_ATCC_199 PPSWALRLARRR---VLLAGVALSAFGVAASPLAGPEGLIQAPPHQYAVK
. * *: * : :. :: .: :*.***.* ** .. * :*
Mflv_0420|M.gilvum_PYR-GCK TVMGAIVAGALLAPLVLDRVDTSHRMLGSPVMVTLGRWSYGLFVWHLAAL
Mvan_0251|M.vanbaalenii_PYR-1 TAMGAVVAGALLAPLVLDRIDTPHRILGSPVMVTLGRWSYGLFVWHLAAL
MSMEG_0319|M.smegmatis_MC2_155 TAMGAVVAGALLAPLVLDHPGTRHRILGSAVMVTLGRWSYGLFVWHLAAL
TH_4330|M.thermoresistible__bu TVMGALLAAALLAPLVLDRPDTPHRFLASAPMVTLGRWSYGIFVWHLAAL
MUL_1127|M.ulcerans_Agy99 TAMGAVVAFALVAPLVLDGPGTPHRLLGSTTMVTLGRWSYGLFIWHLAAL
MMAR_0477|M.marinum_M TAMGAVVAFALVAPLVLDRPGTPHRLLGSTTMVTLGRWSYGLFIWHLAAL
MAV_4941|M.avium_104 TAMGSLVAFALIAPLVLDRMDTPHRVLGTTVMVTLGRWSYGLFIWHLAAL
Mb0233|M.bovis_AF2122/97 TAMGSLVAFALVAPLVLDRPDTSHRLLGSPAMVTLGRWSYGLFIWHLAAL
Rv0228|M.tuberculosis_H37Rv TAMGSLVAFALVAPLVLDRPDTSHRLLGSPAMVTLGRWSYGLFIWHLAAL
MLBr_02580|M.leprae_Br4923 MAMGSLVAFALVAPLVLDRPETLHRVLGSTGMVTLGRWSYGMFVWHLAAL
MAB_4473c|M.abscessus_ATCC_199 IAMGATLAWALLMPLTLDASDTPHRILGSPLMVTLGRWSYGLFIWHLAAL
.**: :* **: **.** * **.*.:. **********:*:******
Mflv_0420|M.gilvum_PYR-GCK AMVFPVIGAFPFNGHFTVVLLLTLLFGFAIAAVSYALVESPCRNALRRWE
Mvan_0251|M.vanbaalenii_PYR-1 AMVFPIIGAFPFNGHFTVVLVLTVLFGFAIAAVSYALVESPCRNALRRWE
MSMEG_0319|M.smegmatis_MC2_155 AMVFPMLGEFLFNGRMLVVLILTLVFGFALAAVSYALVESPCREALRRWE
TH_4330|M.thermoresistible__bu AMVFPMIGEFPFNGNMPVVLVLTVLFTIAIAAVSYGLVEQPCRAAYRRWE
MUL_1127|M.ulcerans_Agy99 DMVFPVIGTFAFTGRMPTVLVLTLIFGFAIAAVSYALVESPCREALRRWE
MMAR_0477|M.marinum_M DMVFPVIGTFAFTGRMPTVLVLTLIFGFAIAAVSYALVESPCREALRRWE
MAV_4941|M.avium_104 AMVFPVLGTFPFTGRMPAVLVLTLIFGFAIAAVSYALVESPCREALRRWE
Mb0233|M.bovis_AF2122/97 AMVFPVIGAFPFTGRMPTVLVLTLIFGFAIAAVSYALVESPCREALRRWE
Rv0228|M.tuberculosis_H37Rv AMVFPVIGAFPFTGRMPTVLVLTLIFGFAIAAVSYALVESPCREALRRWE
MLBr_02580|M.leprae_Br4923 AMVFPVLGAFPFTGRMLMVLMLTLIFSFAIAAVSYALVESPCREALRRWE
MAB_4473c|M.abscessus_ATCC_199 NMVFTVIGRFPFSGHFPSVLILTLIFGFAMAAVSYALVESPSREALRRFQ
***.::* * *.*.: **:**::* :*:*****.***.*.* * **::
Mflv_0420|M.gilvum_PYR-GCK RRNAP-----TPLDSSITEEIEPEVAR-
Mvan_0251|M.vanbaalenii_PYR-1 RRNHP-----TPLDSSVSDEIEPARAR-
MSMEG_0319|M.smegmatis_MC2_155 YRHSRP---VPPLDSSITEQPEPAPAAR
TH_4330|M.thermoresistible__bu MRRARPDAPAPPLDSAVTSVATPISR--
MUL_1127|M.ulcerans_Agy99 KRTEH-----SAG-PDIDREADAIAP--
MMAR_0477|M.marinum_M KRTEH-----SAG-QDIDREADAIAP--
MAV_4941|M.avium_104 KRHQP-----AAPRQLIDAEADAIAP--
Mb0233|M.bovis_AF2122/97 RRNEP-----ISV---GELQADAIAP--
Rv0228|M.tuberculosis_H37Rv RRNEP-----ISV---GELQADAIAP--
MLBr_02580|M.leprae_Br4923 CRRKP-----AVV---PQLNTY------
MAB_4473c|M.abscessus_ATCC_199 QRRDG-----RRTAANATEATEISASS-
*