For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. abscessus ATCC 19977 MAB_4473c (-)

annotation: acyltransferase
coordinates: 4549549 - 4550727
length: 392

SAAPASAPAVHARGFVPALEGMRACAAMGVVVTHTAFQTGHTGGVDGRILGRFDLAVAVFFALSGFLLWR
PHALAAGGGARPAPTGRYFASRFVRIVPAYLAAVFIVLLLLPDAAGARGIVWLANLTLTQLYIPLTLTAG
LTQMWSLAVEVAFYIALPAIALLMRRAPVGWRAPLLTAAGAASLGWSFIPFHPPAGINPLTWPPAFFSWF
VAGMLLAEWSAAPPSWALRLARRRVLLAGVALSAFGVAASPLAGPEGLIQAPPHQYAVKIAMGATLAWAL
LMPLTLDASDTPHRILGSPLMVTLGRWSYGLFIWHLAALNMVFTVIGRFPFSGHFPSVLILTLIFGFAMA
AVSYALVESPSREALRRFQQRRDGRRTAANATEATEISASS*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. abscessus ATCC 19977MAB_4473c--100% (392)acyltransferase
M. abscessus ATCC 19977MAB_1404-2e-3533.07% (381) acyltransferase
M. abscessus ATCC 19977MAB_0401-5e-0824.74% (380) putative acyltransferase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0233-1e-13867.59% (361) integral membrane acyltransferase
M. gilvum PYR-GCKMflv_0420-1e-13265.24% (374) acyltransferase 3
M. tuberculosis H37RvRv0228-1e-13867.59% (361) integral membrane acyltransferase
M. leprae Br4923MLBr_02580-1e-13063.93% (366) putative acyltransferase
M. marinum MMMAR_0477-1e-13967.59% (361) integral membrane acyltransferase
M. avium 104MAV_4941-1e-14068.23% (362) acyltransferase
M. smegmatis MC2 155MSMEG_0319-1e-13266.58% (371) acyltransferase
M. thermoresistible (build 8)TH_4330-1e-12764.54% (361) PUTATIVE acyltransferase 3
M. ulcerans Agy99MUL_1127-1e-13967.59% (361) integral membrane acyltransferase
M. vanbaalenii PYR-1Mvan_0251-1e-13666.22% (373) acyltransferase 3

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_0477|M.marinum_M               --------------------------MVTDGQQVGGTRSFLPPVEGMRAC
MUL_1127|M.ulcerans_Agy99           ------------MYPIRPPVDDGQTVMVTDGQQVGGTRSFLPPVEGMRAC
MAV_4941|M.avium_104                -------------------------MVVSDDQRVGGVRSFLPAVEGMRAC
Mb0233|M.bovis_AF2122/97            -----MGPADESGAPIRPQTPHRHTVLVTNGQVVGGTRGFLPAVEGMRAC
Rv0228|M.tuberculosis_H37Rv         -----MGPADESGAPIRPQTPHRHTVLVTNGQVVGGTRGFLPAVEGMRAC
MLBr_02580|M.leprae_Br4923          ---------------------------MTDVQQVGGIRSFLPAVEGMRAC
Mflv_0420|M.gilvum_PYR-GCK          ---------MSATGTASSRGDVG-----ASGDGVGGTRSFLPAVEGLRAW
Mvan_0251|M.vanbaalenii_PYR-1       ---------MTVTAAP------------ADPSVVGGTRGFLPAVEGLRAC
MSMEG_0319|M.smegmatis_MC2_155      ---------MTTEQSA------------QAEHEVGGTRGFLPAVEGMRAC
TH_4330|M.thermoresistible__bu      MPGTLVAMAVTAEQVAGNPGDSSGASPRDLSHEVSGTRSFLPAVEGLRAC
MAB_4473c|M.abscessus_ATCC_199      ------------------------MSAAPASAPAVHARGFVPALEGMRAC
                                                                     .   *.*:*.:**:** 

MMAR_0477|M.marinum_M               AAMGVVVTHVAFQTGHSSGVAGRLFGRFDLAVAVFFALSGFLLWRGHAAA
MUL_1127|M.ulcerans_Agy99           AAMGVVVTHVAFQTGHSSGVAGRLFGRFDLAVAVFFALSGFLLWRGHAAA
MAV_4941|M.avium_104                AAMGVVVTHVAFQTGHSSGVDGRLFGRFDLAVAVFFALSGFLLWRGHAAA
Mb0233|M.bovis_AF2122/97            AAVGVVVTHVAFQTGHSSGVGGRLFGRFDLAVAVFFAVSGFLLWRGHAAA
Rv0228|M.tuberculosis_H37Rv         AAVGVVVTHVAFQTGHSSGVGGRLFGRFDLAVAVFFAVSGFLLWRGHAAA
MLBr_02580|M.leprae_Br4923          AAIGVVVTHVAFQTGHSSGIVGRLFGRFDLAVAVFFALSGFLLWRGHAAT
Mflv_0420|M.gilvum_PYR-GCK          AAIGVVITHVAFQTGQSGGAVGRILGRFDLAVAVFFALSGFLLWRGHAAA
Mvan_0251|M.vanbaalenii_PYR-1       AAIGVVVTHVAFQTGQSGGVVGRVLGRFDLAVAVFFALSGFLLWRGHAAA
MSMEG_0319|M.smegmatis_MC2_155      AAMGVVLTHVAFQTGHTGGISGRIFGRFDLAVAVFFALSGFLLWRGHAAA
TH_4330|M.thermoresistible__bu      AALGVIVTHVAFQTGHTSGAVGRLLGRFDLAVAVFFALSGFLLWRGHAAA
MAB_4473c|M.abscessus_ATCC_199      AAMGVVVTHTAFQTGHTGGVDGRILGRFDLAVAVFFALSGFLLWRPHALA
                                    **:**::**.*****::.*  **::************:******* ** :

MMAR_0477|M.marinum_M               ARGGSP---RPRTGHYLRSRAVRIMPAYVVAVVVILSLLPDSDHASLTVW
MUL_1127|M.ulcerans_Agy99           ARGGSP---RPRTGHYLRSRAVRIMPAYVVAVVVILSLLPDSDHASLTVW
MAV_4941|M.avium_104                ARDLAP---RPRTGHYLRSRVVRIMPAYLVAVVVILTLLPDADHPSPTVW
Mb0233|M.bovis_AF2122/97            ARDLR---SHPRTGPYLRSRVARIMPAYVVAVVVILSLLPDADHASLTVW
Rv0228|M.tuberculosis_H37Rv         ARDLR---SHPRTGPYLRSRVARIMPAYVVAVVVILSLLPDADHASLTVW
MLBr_02580|M.leprae_Br4923          ARQPVPKDEQPHTSHYLRSRVVRIMPAYLVAVVVILSLLPGANHASWIVW
Mflv_0420|M.gilvum_PYR-GCK          ARGLRS---RPSTGHYLRSRIVRIMPGYLVAVVVILTLLPEAK-ADVTVW
Mvan_0251|M.vanbaalenii_PYR-1       ARGLRS---RPTTGHYLRSRVVRIMPGYLVAVVVIMTLLPDVN-ADFTVW
MSMEG_0319|M.smegmatis_MC2_155      ARGLRP---RPRTGHYLRSRIVRIMPGYVVAVIVILLLLPEAK-ADLTVW
TH_4330|M.thermoresistible__bu      VRGLRP---TPATGRYLRSRVVRIMPGYLVAVVVILLLLPGAT-ADLTVW
MAB_4473c|M.abscessus_ATCC_199      AGGGAR---PAPTGRYFASRFVRIVPAYLAAVFIVLLLLPDAAGARGIVW
                                    .         . *. *: ** .**:*.*:.**.::: ***    .   **

MMAR_0477|M.marinum_M               LANLTLTQIYVPLTLTGGLTQMWSLSVEVGFYLALPLLAFLARRVPVGAR
MUL_1127|M.ulcerans_Agy99           LANLTLTQIYVPLTLTGGLTQMWSLSVEVGFYLALPLLAFLARRVPVGAR
MAV_4941|M.avium_104                LANLTLTQIYVPLTLTGGLTQMWSLSVEVGFYLALPVLALLARRLPVTAR
Mb0233|M.bovis_AF2122/97            LANLTLTQIYVPLTLTGGLTQMWSLSVEVAFYAALPVLALLGRRIPVGAR
Rv0228|M.tuberculosis_H37Rv         LANLTLTQIYVPLTLTGGLTQMWSLSVEVAFYAALPVLALLGRRIPVGAR
MLBr_02580|M.leprae_Br4923          LANLTLTQIYVPLTLTSGLTQMWSLSVEASFYLALPILALLTRRISVRAR
Mflv_0420|M.gilvum_PYR-GCK          LANLTLTQIYVPLTLTAGLTQMWSLSVEMSFYLALPLLALLARRVPVRAR
Mvan_0251|M.vanbaalenii_PYR-1       LANLTLTQIYVPLTLTSGLTQMWSLSVEMSFYLALPLLALLARRLPVRAR
MSMEG_0319|M.smegmatis_MC2_155      LANLTLTQIYVPLTLTAGLTQMWSLSVEVSFYLALPLLALLARRLPVRAR
TH_4330|M.thermoresistible__bu      LANLTLTQIYVPLTLTSGLTQMWSLSVEMTFYLVLPLLALLARQVPVRAR
MAB_4473c|M.abscessus_ATCC_199      LANLTLTQLYIPLTLTAGLTQMWSLAVEVAFYIALPAIALLMRRAPVGWR
                                    ********:*:*****.********:**  ** .** :*:* *: .*  *

MMAR_0477|M.marinum_M               VPVIAAAAALSLAWAWLPVAAGSGMNPLNWPPAFFSWFAAGMLLAEWVHS
MUL_1127|M.ulcerans_Agy99           VPVIAAAAALSLAWAWLPVAAGSGMNPLNWPPAFFSWFAAGMLLAEWVHS
MAV_4941|M.avium_104                VPAIAALGALSWAWGWVPVHPGSGLNPLNWPPAFFSWFAAGMLLAEWVHG
Mb0233|M.bovis_AF2122/97            VPAIAALAALSWAWGWLPLDAGSGINPLTWPPAFFSWFAAGMLLAEWAYS
Rv0228|M.tuberculosis_H37Rv         VPAIAALAALSWAWGWLPLDAGSGINPLTWPPAFFSWFAAGMLLAEWAYS
MLBr_02580|M.leprae_Br4923          VPVIAAAVVISWAWGWVPVHTGSGVNPLTWPPAFFSWFAAGMLLAEWSYS
Mflv_0420|M.gilvum_PYR-GCK          IPVLIGAAAASLLWVHIPFDGASGHNLWNWPPAFFSWFAAGMVLAELTVS
Mvan_0251|M.vanbaalenii_PYR-1       IPAIVVVAAASLFWVRIPFDPDSGHNLWNWPPAFFSWFAAGMVLAELTVG
MSMEG_0319|M.smegmatis_MC2_155      IGVITAVAALSLLWVCIPFAGDTGHNPWNWPPAFFSWFAAGMVLAELTVS
TH_4330|M.thermoresistible__bu      IPVLLATAVLSLFWVRIPFGPDSGLNPWNWPPAFFSWFAAGMILAELTVT
MAB_4473c|M.abscessus_ATCC_199      APLLTAAGAASLGWSFIPFHPPAGINPLTWPPAFFSWFVAGMLLAEWSAA
                                       :    . *  *  :*.   :* *  .*********.***:***    

MMAR_0477|M.marinum_M               PIGLVHRLARHR---VLIGVVAMLAYLVAASPLAGPAGLVQGSATQFAVK
MUL_1127|M.ulcerans_Agy99           PIGLIHRLARHR---VLIGVVAMLAYLVAASPLAGPAGLVQGSATQFAVK
MAV_4941|M.avium_104                GIGRPVRLAQSRTGRVLLAVVAVAAYLVAASPLAGPEGLVPGTPAQFAVK
Mb0233|M.bovis_AF2122/97            PVGLPHRWARRR---VAMAVTALLGYLVAASPLAGPEGLVPGTAAQFAVK
Rv0228|M.tuberculosis_H37Rv         PVGLPHRWARRR---VAMAVTALLGYLVAASPLAGPEGLVPGTAAQFAVK
MLBr_02580|M.leprae_Br4923          RISLPHRLARSR---LTMAVMTLLAYLVAVSPLAGPEGLVPGTATQFAVK
Mflv_0420|M.gilvum_PYR-GCK          PVGWAHRLARRR---VLMALLALTAFLIAASPLAGREGLHPGSIAQVTLK
Mvan_0251|M.vanbaalenii_PYR-1       PVGWAHRLARRR---VLMAVLAVTAFLIAASPLAGREGLHPGSVGQVTLK
MSMEG_0319|M.smegmatis_MC2_155      PYGRVHRLARRR---VLMAAIAVVAFAIAASPLAGKEGLHPGSVGQVMLK
TH_4330|M.thermoresistible__bu      RVGWFHRLARRR---VLMGMFALAAFLVAASPLVGLEGLAPGSIVQVTLK
MAB_4473c|M.abscessus_ATCC_199      PPSWALRLARRR---VLLAGVALSAFGVAASPLAGPEGLIQAPPHQYAVK
                                      .   * *: *   : :.  :: .: :*.***.*  **  ..  *  :*

MMAR_0477|M.marinum_M               TAMGAVVAFALVAPLVLDRPGTPHRLLGSTTMVTLGRWSYGLFIWHLAAL
MUL_1127|M.ulcerans_Agy99           TAMGAVVAFALVAPLVLDGPGTPHRLLGSTTMVTLGRWSYGLFIWHLAAL
MAV_4941|M.avium_104                TAMGSLVAFALIAPLVLDRMDTPHRVLGTTVMVTLGRWSYGLFIWHLAAL
Mb0233|M.bovis_AF2122/97            TAMGSLVAFALVAPLVLDRPDTSHRLLGSPAMVTLGRWSYGLFIWHLAAL
Rv0228|M.tuberculosis_H37Rv         TAMGSLVAFALVAPLVLDRPDTSHRLLGSPAMVTLGRWSYGLFIWHLAAL
MLBr_02580|M.leprae_Br4923          MAMGSLVAFALVAPLVLDRPETLHRVLGSTGMVTLGRWSYGMFVWHLAAL
Mflv_0420|M.gilvum_PYR-GCK          TVMGAIVAGALLAPLVLDRVDTSHRMLGSPVMVTLGRWSYGLFVWHLAAL
Mvan_0251|M.vanbaalenii_PYR-1       TAMGAVVAGALLAPLVLDRIDTPHRILGSPVMVTLGRWSYGLFVWHLAAL
MSMEG_0319|M.smegmatis_MC2_155      TAMGAVVAGALLAPLVLDHPGTRHRILGSAVMVTLGRWSYGLFVWHLAAL
TH_4330|M.thermoresistible__bu      TVMGALLAAALLAPLVLDRPDTPHRFLASAPMVTLGRWSYGIFVWHLAAL
MAB_4473c|M.abscessus_ATCC_199      IAMGATLAWALLMPLTLDASDTPHRILGSPLMVTLGRWSYGLFIWHLAAL
                                     .**: :* **: **.**   * **.*.:. **********:*:******

MMAR_0477|M.marinum_M               DMVFPVIGTFAFTGRMPTVLVLTLIFGFAIAAVSYALVESPCREALRRWE
MUL_1127|M.ulcerans_Agy99           DMVFPVIGTFAFTGRMPTVLVLTLIFGFAIAAVSYALVESPCREALRRWE
MAV_4941|M.avium_104                AMVFPVLGTFPFTGRMPAVLVLTLIFGFAIAAVSYALVESPCREALRRWE
Mb0233|M.bovis_AF2122/97            AMVFPVIGAFPFTGRMPTVLVLTLIFGFAIAAVSYALVESPCREALRRWE
Rv0228|M.tuberculosis_H37Rv         AMVFPVIGAFPFTGRMPTVLVLTLIFGFAIAAVSYALVESPCREALRRWE
MLBr_02580|M.leprae_Br4923          AMVFPVLGAFPFTGRMLMVLMLTLIFSFAIAAVSYALVESPCREALRRWE
Mflv_0420|M.gilvum_PYR-GCK          AMVFPVIGAFPFNGHFTVVLLLTLLFGFAIAAVSYALVESPCRNALRRWE
Mvan_0251|M.vanbaalenii_PYR-1       AMVFPIIGAFPFNGHFTVVLVLTVLFGFAIAAVSYALVESPCRNALRRWE
MSMEG_0319|M.smegmatis_MC2_155      AMVFPMLGEFLFNGRMLVVLILTLVFGFALAAVSYALVESPCREALRRWE
TH_4330|M.thermoresistible__bu      AMVFPMIGEFPFNGNMPVVLVLTVLFTIAIAAVSYGLVEQPCRAAYRRWE
MAB_4473c|M.abscessus_ATCC_199      NMVFTVIGRFPFSGHFPSVLILTLIFGFAMAAVSYALVESPSREALRRFQ
                                     ***.::* * *.*.:  **:**::* :*:*****.***.*.* * **::

MMAR_0477|M.marinum_M               KRTEH-----SAG-QDIDREADAIAP--
MUL_1127|M.ulcerans_Agy99           KRTEH-----SAG-PDIDREADAIAP--
MAV_4941|M.avium_104                KRHQP-----AAPRQLIDAEADAIAP--
Mb0233|M.bovis_AF2122/97            RRNEP-----ISV---GELQADAIAP--
Rv0228|M.tuberculosis_H37Rv         RRNEP-----ISV---GELQADAIAP--
MLBr_02580|M.leprae_Br4923          CRRKP-----AVV---PQLNTY------
Mflv_0420|M.gilvum_PYR-GCK          RRNAP-----TPLDSSITEEIEPEVAR-
Mvan_0251|M.vanbaalenii_PYR-1       RRNHP-----TPLDSSVSDEIEPARAR-
MSMEG_0319|M.smegmatis_MC2_155      YRHSRP---VPPLDSSITEQPEPAPAAR
TH_4330|M.thermoresistible__bu      MRRARPDAPAPPLDSAVTSVATPISR--
MAB_4473c|M.abscessus_ATCC_199      QRRDG-----RRTAANATEATEISASS-
                                     *