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LWVERRCNGSPVPRRYPPRSAESRTPSATEGINVSAFEPNIRPDCTDALTATLGQRIMVIDGAMGTAIQR DRPDEAGYRGERFKDWPSDLVGNNDLLSLTQPQIIEGIHREYLQAGADILETNTFNANAVSLSDYDMAEL AYELNYAGAALARAAADEFSTPEKPRYVAGALGPTTRTASISPDVNDPGARNVSYDQLVAAYLEAANGLV DGGADIIIIETIFDSLNAKAAVFAVETLFEDRGRRWPVIISGTITDASGRTLSGQVTEAFWNAIRHAKPI AVGLNCALGAPEMRPYIAEMARIADTFVSCYPNAGLPNAFGEYDETPEHQAGYIAEFADAGLVNLVGGCC GTAPPHIAEIAKVVEGKAPRELPEIPVATRLSGLEPLNITDDSLFENIGERTNITGSARFRNLIKAEDYD TALSVALQQVEVGAQVIDINMDEGMIDGVAAMDRFTKLIAAEPDISRVPVMIDSSKWEVIEAGLKNVQGK PIVNSISMKEGEEKFVREARLCRKYGAAVVVMAFDEKGQADNLERRKEICGRAYRILTEEVGFPAEDIIF DPNCFALATGIEEHATYGIDFIEACAWIKENLPGVHISGGISNVSFSFRGNNPVREAIHAVFLFHAIKAG LDMGIVNAGALVPYDSIDPELRERIEDVVLNRREDAAERLLEIAERFNTKGKPEDPAAAEWRSLPVRERI THALVKGIDAHVDADTEELRAEIAAAGGRLIEVIEGPLMDGMNVVGDLFGAGKMFLPQVVKSARVMKKAV AYLLPFIEAEKAQSGSTEQDKTNGIIIMATVKGDVHDIGKNIVGVVLQCNNYTVVDLGVMVPAEKILAAA REYDADIIGLSGLITPSLDEMVNFAAAMEREGMQIPLLIGGATTSRAHTAVKVAPRRSGPVVWVKDASRS VPVAAALLDDKQRPGLLEATAADYAALRERHSQKNERPMLTLEKARANRTPIDWDGYTPPLPAQGLGVRE FHDYDLAELREYIDWQPFFNAWEMKGRFPDILNNPATGEAARKLYNDAQEMLDTLIREKWLTANGVIGFF PANAVGDDIEVYTDETRAEVLTTLHNLRQQGEHRAGIPNRSLGDFIAPKDTGLADYVGAFAVTAGLGSQT KIVEFKEALDDYSAILLESIADRLAEAFAERMHQRVREEFWGYQPDEQLDNEALIGERYVGIRPAPGYPA CPEHTEKTTLFELMDVTKRTGIELTESMAMWPGAAVSGWYFSHPQSQYFVVGRMAQDQVADYAKRKGWTL PEAERWLGPNLGYNPED
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. ulcerans Agy99 | MUL_0395 | metH | - | 100% (1277) | B12-dependent methionine synthase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2148c | metH | 1e-158 | 33.74% (1239) | 5-methyltetrahydrofolate--homocystein methyltransferase |
M. gilvum PYR-GCK | Mflv_3053 | metH | 0.0 | 90.32% (1250) | B12-dependent methionine synthase |
M. tuberculosis H37Rv | Rv2124c | metH | 1e-158 | 33.66% (1239) | 5-methyltetrahydrofolate--homocystein methyltransferase |
M. leprae Br4923 | MLBr_01307 | metH | 1e-158 | 32.48% (1250) | 5-methyltetrahydrofolate-homocysteine methyltransferase |
M. abscessus ATCC 19977 | MAB_2129 | metH | 0.0 | 90.26% (1253) | B12-dependent methionine synthase |
M. marinum M | MMAR_4825 | metH | 0.0 | 99.60% (1244) | 5-methyltetrahydrofolate--homocysteine methyltransferase, MetH |
M. avium 104 | MAV_2379 | metH | 0.0 | 90.05% (1246) | B12-dependent methionine synthase |
M. smegmatis MC2 155 | MSMEG_4185 | metH | 0.0 | 90.31% (1239) | B12-dependent methionine synthase |
M. thermoresistible (build 8) | TH_0958 | metH | 1e-160 | 33.65% (1245) | Probable 5-methyltetrahydrofolate--homocystein |
M. vanbaalenii PYR-1 | Mvan_3474 | metH | 0.0 | 90.35% (1243) | B12-dependent methionine synthase |
CLUSTAL 2.0.9 multiple sequence alignment MUL_0395|M.ulcerans_Agy99 MWVERRCNGSPVPRRYPPRSAESRTPSATEGINVSAFEPNIRPDCTDALT MMAR_4825|M.marinum_M ---------------------------------MSAFEPNIRPDCTDALT MAV_2379|M.avium_104 ------------------------MTAPVTTPASDSFAPNIRPDCTDELT Mvan_3474|M.vanbaalenii_PYR-1 ----------------------------MNSADPNIWEPNIRPDCTDELK MAB_2129|M.abscessus_ATCC_1997 ---------------------------------MTNLQPNVRPDCTEALT Mflv_3053|M.gilvum_PYR-GCK --------------------------MEGAHVNAVEFEPNIRPDCTEELT MSMEG_4185|M.smegmatis_MC2_155 ----------------------------MNAVRSETLAPNIRPDCTDALT Mb2148c|M.bovis_AF2122/97 ------------------------------------MTAADKHLYDTDLL Rv2124c|M.tuberculosis_H37Rv ------------------------------------MTAADKHLYDTDLL MLBr_01307|M.leprae_Br4923 ----------------------------------MRVTAANQHQYDTDLL TH_0958|M.thermoresistible__bu ------------------------MKQVAHDDYAVGVTPVDTAVYDTDLL . * MUL_0395|M.ulcerans_Agy99 ATLGQRIMVIDGAMGTAIQRDRPDEAGYRGERFKDWPSDLVGNNDLLSLT MMAR_4825|M.marinum_M AALGQRIMVIDGAMGTAIQRDRPDEAGYRGERFKDWPSDLVGNNDLLSLT MAV_2379|M.avium_104 AALRQRIMVIDGAMGTAIQRDRPDEAGYRGERFKDWPSDLVGNNDLLNLT Mvan_3474|M.vanbaalenii_PYR-1 VALGRRIVVIDGAMGTAIQRDRPDEAGYRGERFKDWPSDLVGNNDLLTLT MAB_2129|M.abscessus_ATCC_1997 AALEQRILVIDGAMGTAIQRDRPDEAGYRGERFADWPSDLVGNNDLLTLT Mflv_3053|M.gilvum_PYR-GCK AALRERIMVIDGAMGTAIQRDRPDEAGYRGDRFTEWPTALQGNNDLLNLT MSMEG_4185|M.smegmatis_MC2_155 AALRQRILVIDGAMGTAIQRDRPDEAGYRGERFKDWPSDLVGNNDLLNLT Mb2148c|M.bovis_AF2122/97 DVLSQRVMVGDGAMGTQLQAADLTLDDFRG---------LEGCNEILNET Rv2124c|M.tuberculosis_H37Rv DVLSQRVMVGDGAMGTQLQAADLTLDDFRG---------LEGCNEILNET MLBr_01307|M.leprae_Br4923 ETLAQRVMVGDGAMGTQLQDAELTLDDFRG---------LEGCNEILNET TH_0958|M.thermoresistible__bu ETLSRRVMVGDGAMGTQLQAADLTLDDFNG---------LEGCNEILNET .* .*::* ****** :* .:.* * * *::*. * MUL_0395|M.ulcerans_Agy99 QPQIIEGIHREYLQAGADILETNTFNANAVSLSDYDMAELAYELNYAGAA MMAR_4825|M.marinum_M QPQIIEGIHREYLQAGADILETNTFNANAVSLSDYDMAELAYELNYAGAA MAV_2379|M.avium_104 QPQIIEGIHREYLEAGADILETNTFNANAISLSDYGMEELSYELNYAGAA Mvan_3474|M.vanbaalenii_PYR-1 QPQIIEGIHREYLEAGADILETNTFNANAVSLSDYGMEKLSYELNYAGAA MAB_2129|M.abscessus_ATCC_1997 QPHIIEGIHREYLEAGADILETNTFNANAVSLSDYGMEELSYELNYAGAA Mflv_3053|M.gilvum_PYR-GCK QPQIIEAIHREYLDAGADILETNTFNANAISLSDYDMTDLAYELNYAGAA MSMEG_4185|M.smegmatis_MC2_155 QPHIIEAIHREYLDAGADLLETNTFNANAVSLSDYGMQELAYELNYAGAA Mb2148c|M.bovis_AF2122/97 RPDVLETIHRNYFEAGADAVETNTFGCNLSNLGDYDIADRIRDLSQKGTA Rv2124c|M.tuberculosis_H37Rv RPDVLETIHRNYFEAGADAVETNTFGCNLSNLGDYDIADRIRDLSQKGTA MLBr_01307|M.leprae_Br4923 RPDVLETIHRRYFEAGADLVETNTFGCNLSNLGDYDIADKIRDLSQRGTV TH_0958|M.thermoresistible__bu RPDVIAEIHRNYLAAGADAVETNTFGCNLSNLGDYDIADKIRSLSEQGTA :*.:: ***.*: **** :*****..* .*.**.: . .*. *:. MUL_0395|M.ulcerans_Agy99 LARAAADEFSTPEKPRYVAGALGPTTRTASISPDVNDPGARNVSYDQLVA MMAR_4825|M.marinum_M LARAAADEFSTPEKPRYVAGALGPTTRTASISPDVNDPGARNVSYDQLVA MAV_2379|M.avium_104 LARKAADEFSTPDKPRYVAGALGPTSRTASISPDVNDPGARNVTYDELVA Mvan_3474|M.vanbaalenii_PYR-1 LARKACDEFSTPDKPRYVAGALGPTTRTASISPDVNDPGARNVSYDQLVA MAB_2129|M.abscessus_ATCC_1997 LARVAADEYSTPAKPRYVAGALGPTTRTASISPDVNDPGARNVSYDQLVA Mflv_3053|M.gilvum_PYR-GCK LARKAADEYSTADKPRYVAGAIGPTTRTASISPDVNDPGARNVSYDQLVA MSMEG_4185|M.smegmatis_MC2_155 LARAACDEYSTPDKPRYVAGALGPTTRTASISPDVNDPGARNVSYDQLAE Mb2148c|M.bovis_AF2122/97 IARRVADELGSPDRKRYVLGSMGPGTKLPTLG---------HTEYAVIRD Rv2124c|M.tuberculosis_H37Rv IARRVADELGSPDRKRYVLGSMGPGTKLPTLG---------HTEYAVIRD MLBr_01307|M.leprae_Br4923 IARRVADELTTPDHKRYVLGSMGPGTKLPTLG---------HTEYRVVRD TH_0958|M.thermoresistible__bu IARRVADEMSTPDHRRYVLAAMGPGTKLPTLG---------HTEFGVIRD :** ..** :. : *** .::** :: .::. :. : : MUL_0395|M.ulcerans_Agy99 AYLEAANGLVDGGADIIIIETIFDSLNAKAAVFAVETLFEDRGRRWPVII MMAR_4825|M.marinum_M AYLEAANGLVDGGADIIIIETIFDSLNAKAAVFAVETLFEDRGRRWPVII MAV_2379|M.avium_104 AYLEAANGLVDGGVDLLIVETIFDTLNAKAAVFALETLFEQRGRRWPVII Mvan_3474|M.vanbaalenii_PYR-1 AYLDAASGLVDGGADLLIVETIFDTLNAKAAVFAIETLFEDRGRRWPVII MAB_2129|M.abscessus_ATCC_1997 AYLEAANGLVDGGADIILVETIFDSLNAKAAVFAIETLFEQRGRRWPIII Mflv_3053|M.gilvum_PYR-GCK AYLEAANGLVDGGSDLIMIETIFDSLNAKAAVFAVETLFEERGRRWPVII MSMEG_4185|M.smegmatis_MC2_155 AYLEAARGLVDGGADLIIVETIFDTLNAKAAIFAIETLFEERGRRWPVII Mb2148c|M.bovis_AF2122/97 AYTEAALGMLDGGADAILVETCQDLLQLKAAVLGSRRAMTRAGRHIPVFA Rv2124c|M.tuberculosis_H37Rv AYTEAALGMLDGGADAILVETCQDLLQLKAAVLGSRRAMTRAGRHIPVFA MLBr_01307|M.leprae_Br4923 AYTESALGMLDGGADAVLVETCQDLLQLKAAVLGSRRAMTQAGRHIPVFV TH_0958|M.thermoresistible__bu AYIEAALGMLDGGADAILIETCQDLLQLKAAVLGARRAMARAGRHIPIIT ** ::* *::*** * :::** * *: ***::. . : **: *:: MUL_0395|M.ulcerans_Agy99 SGTITDASGRTLSGQVTEAFWNAIRHAKPIAVGLNCALGAPEMRPYIAEM MMAR_4825|M.marinum_M SGTITDASGRTLSGQVTEAFWNAIRHAKPIAVGLNCALGAPEMRPYIAEM MAV_2379|M.avium_104 SGTITDASGRTLSGQVTEAFWNSIRHAKPIAVGLNCALGAPEMRPYIAEV Mvan_3474|M.vanbaalenii_PYR-1 SGTITDASGRTLSGQVTEAFWNSVRHARPLAVGLNCALGAPEMRPYLAEM MAB_2129|M.abscessus_ATCC_1997 SGTITDASGRTLSGQVTEAFWNAIRHARPIAVGLNCALGAPEMRPYIAEM Mflv_3053|M.gilvum_PYR-GCK SGTITDASGRTLSGQVTEAFWNAIRHAKPLAVGLNCALGAPEMRPYIAEV MSMEG_4185|M.smegmatis_MC2_155 SGTITDASGRTLSGQVTEAFWNSIRHAQPLAVGLNCALGAPEMRPYIAEM Mb2148c|M.bovis_AF2122/97 H-VTVETTGTMLLGSEIGAALTAVEPLGVDMIGLNCATGPAEMSEHLRHL Rv2124c|M.tuberculosis_H37Rv H-VTVETTGTMLLGSEIGAALTAVEPLGVDMIGLNCATGPAEMSEHLRHL MLBr_01307|M.leprae_Br4923 H-VTVETTGTMLLGSEIGAALAAVEPLGVDMIGLNCATGPAEMSEHLRHL TH_0958|M.thermoresistible__bu H-VTVETTGTMLLGSEIGAALTAIEPLGVDVIGLNCATGPAEMSEHLRYL . .:::* * *. * ::. :***** *..** :: : MUL_0395|M.ulcerans_Agy99 ARIADTFVSCYPNAGLPNAFG---EYDETPEHQAGYIAEFADAGLVNLVG MMAR_4825|M.marinum_M ARIADTFVSCYPNAGLPNAFG---EYDETPEHQAGYIAEFADAGLVNLVG MAV_2379|M.avium_104 SRIADTFVSCYPNAGLPNAFG---EYDESPERQASYIADFAEAGLVNIVG Mvan_3474|M.vanbaalenii_PYR-1 SRIADTFVSCYPNAGLPNAFG---EYDESPTRQAGYVAEFAEAGLVNLVG MAB_2129|M.abscessus_ATCC_1997 SRIADTFVSCYPNAGLPNAFG---EYDESPEHQAGYLAEFAEAGLVNLVG Mflv_3053|M.gilvum_PYR-GCK ARIADTFVSCYPNAGLPNAFG---EYDESPERQASYIAEFAEAGLVNLVG MSMEG_4185|M.smegmatis_MC2_155 SRIADTFVSCYPNAGLPNAFG---EYDESPKRQASYVEEFAEAGFVNLVG Mb2148c|M.bovis_AF2122/97 SRHARIPVSVMPNAGLPVLGAKGAEYPLLPDELAEALAGFIAEFGLSLVG Rv2124c|M.tuberculosis_H37Rv SRHARIPVSVMPNAGLPVLGAKGAEYPLLPDELAEALAGFIAEFGLSLVG MLBr_01307|M.leprae_Br4923 SKHARIPVSVMPNAGLPVLGAKGAEYPLQPDELAEALAGFIAEFGLSLVG TH_0958|M.thermoresistible__bu SRHSRLPVSVMPNAGLPVLGPDGAVYPLRPDELAEALAGFVSEFGLSLVG :: : ** ****** * * . * : * :.:** MUL_0395|M.ulcerans_Agy99 GCCGTAPPHIAEIAKVVEG----KAPRELPEIPVATRLSGLEPLN-ITDD MMAR_4825|M.marinum_M GCCGTAPPHIAEIAKVVEG----KAPRELPEIPVATRLSGLEPLN-ISDD MAV_2379|M.avium_104 GCCGTAPPHIAEIAKVVEG----KPPREVPQIPVATRLSGLEPLN-ITDD Mvan_3474|M.vanbaalenii_PYR-1 GCCGTTPAHIAEIARVVDG----KPPRKVPEIPVATRLAGLEPLN-ITDD MAB_2129|M.abscessus_ATCC_1997 GCCGTAPAHIAEIAKVVEG----VKPRDVPSIDVATRLSGLEPLN-ITDD Mflv_3053|M.gilvum_PYR-GCK GCCGTAPPHIAEIAKVVDG----KTPRELPQIPVATRLSGLEPLN-INDE MSMEG_4185|M.smegmatis_MC2_155 GCCGTTPAHIAEIAKVVEG----KPPRQVPEIPVATRLSGLEPLN-IDED Mb2148c|M.bovis_AF2122/97 GCCGTTPAHIREVAAAVAN-----IKRPERQVSYEPSVSSLYTAIPFAQD Rv2124c|M.tuberculosis_H37Rv GCCGTTPAHIREVAAAVAN-----IKRPERQVSYEPSVSSLYTAIPFAQD MLBr_01307|M.leprae_Br4923 GCCGTTPDHIREVAAAVARCNDGTVPRGERHVTYEPSVSSLYTAIPFAQK TH_0958|M.thermoresistible__bu GCCGTTPEHIRQVVDAVSG-----VQRAGRQISYEPGLSSLYTSTPFAQD *****:* ** ::. .* * : . ::.* . : :. MUL_0395|M.ulcerans_Agy99 SLFENIGERTNITGSARFRNLIKAEDYDTALSVALQQVEVGAQVIDINMD MMAR_4825|M.marinum_M SLFVNIGERTNITGSARFRNLIKAEDYDTALSVALQQVEVGAQVIDINMD MAV_2379|M.avium_104 SLFVNIGERTNITGSARFRNLIKAEDYDTALSVALQQVEVGAQVIDINMD Mvan_3474|M.vanbaalenii_PYR-1 SLFVNIGERTNITGSARFRNLIKAEDYDTALSVALQQVEVGAQVIDINMD MAB_2129|M.abscessus_ATCC_1997 SLFVNIGERTNITGSARFRNLIKAEDYDTALSVALQQVEVGAQVIDINMD Mflv_3053|M.gilvum_PYR-GCK SLFVNIGERTNITGSARFRNLIKAEDYDTALSVALQQVEVGAQVIDINMD MSMEG_4185|M.smegmatis_MC2_155 SLFVNIGERTNITGSARFRNLIKAEDYDTALSVALQQVEVGAQVIDINMD Mb2148c|M.bovis_AF2122/97 ASVLVIGERTNANGSKGFREAMIAEDYQKCLDIAKDQTRDGAHLLDLCVD Rv2124c|M.tuberculosis_H37Rv ASVLVIGERTNANGSKGFREAMIAEDYQKCLDIAKDQTRDGAHLLDLCVD MLBr_01307|M.leprae_Br4923 PSVLMIGERTNANGSKVFREAMIAEDYQKCLDIAKDQTRGGAHLLDLCVD TH_0958|M.thermoresistible__bu ASVLMIGERTNANGSKAFREAMIAEDYQRCLDIAKEQTRDGAHLLDLCVD . . ****** .** **: : ****: .*.:* :*.. **:::*: :* MUL_0395|M.ulcerans_Agy99 EGMIDGVAAMDRFTKLIAAEPDISRVPVMIDSSKWEVIEAGLKNVQGKPI MMAR_4825|M.marinum_M EGMIDGVAAMDRFTKLIAAEPDISRVPVMIDSSKWEVIEAGLKNVQGKPI MAV_2379|M.avium_104 EGMIDGVAAMDRFTRLIAAEPDISRVPVMIDSSKWEVIEAGLKNVQGKPI Mvan_3474|M.vanbaalenii_PYR-1 EGMIDGVAAMDRFTKLIAAEPDISRVPVMIDSSKWEVIEAGLKNVQGKPI MAB_2129|M.abscessus_ATCC_1997 EGMIDGVAAMDRFTKLIAAEPDISRVPVMIDSSKWEVIEAGLKNVQGKPI Mflv_3053|M.gilvum_PYR-GCK EGMIDGVAAMDRFTKLIASEPDISRVPVMIDSSKWEVIEAGLKNVQGKPI MSMEG_4185|M.smegmatis_MC2_155 EGMIDGVAAMDRFTKLIASEPDISRVPVMIDSSKWEVIEAGLKNVQGKPI Mb2148c|M.bovis_AF2122/97 YVGRDGVADMKALASRLAT---SSTLPIMLDSTETAVLQAGLEHLGGRCA Rv2124c|M.tuberculosis_H37Rv YVGRDGVADMKALASRLAT---SSTLPIMLDSTETAVLQAGLEHLGGRCA MLBr_01307|M.leprae_Br4923 YVGRNGVADMKALAGRLAT---VSTLPIMLDSTEIPVLQAGLEHLGGRCV TH_0958|M.thermoresistible__bu YVGRDGVADMKALASRLAT---ASTLPIMLDSTETDVLRAGLEHLGGRCA :*** *. :: :*: * :*:*:**:: *:.***::: *: MUL_0395|M.ulcerans_Agy99 VNSISMKEG---EEKFVREARLCRKYGAAVVVMAFDEKGQADNLERRKEI MMAR_4825|M.marinum_M VNSISMKEG---EEKFVREARLCRKYGAAVVVMAFDEKGQADNLERRKEI MAV_2379|M.avium_104 VNSISLKEG---EEKFVREARLCRKYGAAVVVMAFDEQGQADNLERRKQI Mvan_3474|M.vanbaalenii_PYR-1 VNSISMKEG---EEKFIREARLCRKYGAAVVVMAFDEQGQADNLERRKQI MAB_2129|M.abscessus_ATCC_1997 VNSISMKEG---EEKFIREARLCRKYGAAVVVMAFDEKGQADNLERRKEI Mflv_3053|M.gilvum_PYR-GCK VNSISMKEG---EEKFIREAQLCRKYGAAVVVMAFDEQGQADNLERRKEI MSMEG_4185|M.smegmatis_MC2_155 VNSISLKEG---EEKFVREARLCRKYGAAVVVMAFDEQGQADNLERRKQI Mb2148c|M.bovis_AF2122/97 INSVNYEDGDGPESRFAKTMALVAEHGAAVVALTIDEEGQARTAQKKVEI Rv2124c|M.tuberculosis_H37Rv INSVNYEDGDGPESRFAKTMALVAEHGAAVVALTIDEEGQARTAQKKVEI MLBr_01307|M.leprae_Br4923 INSVNYEDGDGPESRFVKTMELVAEHGAAVVALTIDEQGQARTVEKKVEV TH_0958|M.thermoresistible__bu VNSVNYEDGAGPESRFHKTMELVAEHGAAVVALTIDEEGQARTAEHKVAI :**:. ::* *.:* : * ::*****.:::**:*** . ::: : MUL_0395|M.ulcerans_Agy99 CGRAYRILTEEVGFPAEDIIFDPNCFALATGIEEHATYGIDFIEACAWIK MMAR_4825|M.marinum_M CGRAYRILTEEVGFPAEDIIFDPNCFALATGIEEHATYGIDFIEACAWIK MAV_2379|M.avium_104 CARAYRVLTEEVGFPPEDIIFDPNCFALATGIEEHATYGIDFIEACAWIK Mvan_3474|M.vanbaalenii_PYR-1 CGRAYRILTEEVGFPAEDIIFDPNCFALATGIEEHASYGIDFIEACAWIK MAB_2129|M.abscessus_ATCC_1997 CGRAYRILTEEVGFPAEDIIFDPNCFALATGIEEHATYGIDFIEACAWIK Mflv_3053|M.gilvum_PYR-GCK CGRAYRILTEKVGFPAEDIIFDPNCFALATGIEEHATYGIDFIEACAWIK MSMEG_4185|M.smegmatis_MC2_155 CGRAYKTLTEEVGFPAEDIIFDPNCFALATGIEEHATYGIDFIEACRWIK Mb2148c|M.bovis_AF2122/97 AERLINDITGNWGVDESSILIDTLTFTIATGQEESRRDGIETIEAIRELK Rv2124c|M.tuberculosis_H37Rv AERLINDITGNWGVDESSILIDTLTFTIATGQEESRRDGIETIEAIRELK MLBr_01307|M.leprae_Br4923 AERLINDITSNWGVDKSAILIDCLTFTIATGQEESRKDGIETIDAIRELK TH_0958|M.thermoresistible__bu AERLIEDITTNWGVEKSSILVDCLTFTICTGQEESRRDGIETIEAIRELK . * . :* : *. . *:.* *::.** ** **: *:* :* MUL_0395|M.ulcerans_Agy99 ENLPGVHISGGISNVSFSFRGNNPVREAIHAVFLFHAIKAGLDMGIVNAG MMAR_4825|M.marinum_M ENLPGVHISGGISNVSFSFRGNNPVREAIHAVFLFHAIKAGLDMGIVNAG MAV_2379|M.avium_104 ENLPGVHLSGGISNVSFSFRGNNPVREAIHSVFLFHAIKAGLDMGIVNAG Mvan_3474|M.vanbaalenii_PYR-1 ENLPGVHISGGISNVSFSFRGNNPVREAIHAVFLFHAIKAGLDMGIVNAG MAB_2129|M.abscessus_ATCC_1997 ENLPGVHISGGISNVSFSFRGNNPVREAIHAVFLFHAIKAGLDMGIVNAG Mflv_3053|M.gilvum_PYR-GCK ENLPGVHISGGISNVSFSFRGNNPVREAIHAVFLFHAIKAGLDMGIVNAG MSMEG_4185|M.smegmatis_MC2_155 ENLPGVHISGGISNVSFSFRGNNPVREAIHAVFLFHAIKAGLDMGIVNAG Mb2148c|M.bovis_AF2122/97 KRHPDVQTTLGLSNISFGLN--PAARQVLNSVFLHECQEAGLDSAIVHAS Rv2124c|M.tuberculosis_H37Rv KRHPDVQTTLGLSNISFGLN--PAARQVLNSVFLHECQEAGLDSAIVHAS MLBr_01307|M.leprae_Br4923 KRHPAVQTTLGLSNISFGLN--PSARQVLNSVFLHECQEAGLDSAIVHAS TH_0958|M.thermoresistible__bu KRHPDVQTTLGLSNISFGLN--PAARQVLNSVFLHECREAGLDSAIVHAS :. * *: : *:**:**.:. ..*:.:::***... :**** .**:*. MUL_0395|M.ulcerans_Agy99 ALVPYDSIDPELRERIEDVVLNRREDAAERLLEIAERFN-TKGKP--EDP MMAR_4825|M.marinum_M ALVPYDSIDPELRERIEDVVLNRREDAAERLLEIAERFN-TKGKS--EDP MAV_2379|M.avium_104 ALVPYDSIDPELRDRIEDVVLNRREDAAERLLEIAERFNKSADAS--EDS Mvan_3474|M.vanbaalenii_PYR-1 ALVPYDSIDPELRDRIEDVVLNRREDAAERLLEIAERFN-SKGET--EDA MAB_2129|M.abscessus_ATCC_1997 ALVPYDSIDSELRDRIEDVVLNRRADAAERLLEIAERFNSTENSGGGDDR Mflv_3053|M.gilvum_PYR-GCK ALVPYDSIDPELRDRIEDVVLNRRADAAERLLEIAERFN-KADKG--EDP MSMEG_4185|M.smegmatis_MC2_155 ALVPYDSIDPELRERIEDVVLNRREDAAERLLEIAERFN-SKDKG--EDP Mb2148c|M.bovis_AF2122/97 KILPMNRIPEEQRNVALDLVYDRRREDYDPLQELMRLFEGVSAASS-KED Rv2124c|M.tuberculosis_H37Rv KILPMNRIPEEQRNVALDLVYDRRREDYDPLQELMRLFEGVSAASS-KED MLBr_01307|M.leprae_Br4923 KILPINRIPEEQRQAALDLVYDRRREGYDPLQKLMWLFKGVSSPSS-KET TH_0958|M.thermoresistible__bu KILPMNRIDEKQREVALDLIYDRRREGYDPLQELMTMFEGVSTADS-KES ::* : * : *: *:: :** : : * :: *: .: MUL_0395|M.ulcerans_Agy99 AAAEWRSLPVRERITHALVKGIDAHVDADTEELRAEIAAAGGRLIEVIEG MMAR_4825|M.marinum_M AAAEWRSLPVRERITHALVKGIDAHVDADTEELRAEIAAAGGRPIEVIEG MAV_2379|M.avium_104 AAAEWRGLPVRERITHALVKGIDAHVDEDTEELRAEIAAAGGRPIEVIEG Mvan_3474|M.vanbaalenii_PYR-1 GVAEWRSLPVRERITHALVKGIDAHVDDDTEELRAEIADAGGRPIEVIEG MAB_2129|M.abscessus_ATCC_1997 AAQEWRSLPVRERITHALVKGIDAHVDDDTEELRAEIAAAGGRPIEVIEG Mflv_3053|M.gilvum_PYR-GCK QAAEWRSLPVRERITHALVKGIDAHVDDDTEELRAEIEAAGGRPIEVIEG MSMEG_4185|M.smegmatis_MC2_155 AAAEWRSLPVRERITHALVKGIDAHVDDDTEELRAEIAAAGGRPIEVIEG Mb2148c|M.bovis_AF2122/97 RLAELAGLPLFERLAQRIVDGERNGLDADLDEAMTQKP-----PLQIINE Rv2124c|M.tuberculosis_H37Rv RLAELAGLPLFERLAQRIVDGERNGLDADLDEAMTQKP-----PLQIINE MLBr_01307|M.leprae_Br4923 REAELAKLPLFDRLAQRIVDGERNGLDVDLDEAMTQKP-----PLAIINE TH_0958|M.thermoresistible__bu RAAELAKLPVLERLAQRIVDGERNGLEADLDEAMTIKP-----PLEIINE * **: :*::: :*.* :: * :* : : :*: MUL_0395|M.ulcerans_Agy99 PLMDGMNVVGDLFGAGKMFLPQVVKSARVMKKAVAYLLPFIEAEKAQSGS MMAR_4825|M.marinum_M PLMDGMNVVGDLFGAGKMFLPQVVKSARVMKKAVAYLLPFIEAEKAQSGS MAV_2379|M.avium_104 PLMDGMNVVGDLFGSGKMFLPQVVKSARVMKKAVAYLLPFIEAEKEESGV Mvan_3474|M.vanbaalenii_PYR-1 PLMDGMNVVGDLFGAGKMFLPQVVKSARVMKKAVAYLLPFIEAEKAENGT MAB_2129|M.abscessus_ATCC_1997 PLMDGMNVVGDLFGSGKMFLPQVVKSARVMKKAVAYLLPFIEAEKEDNGT Mflv_3053|M.gilvum_PYR-GCK PLMDGMNVVGDLFGSGKMFLPQVVKSARVMKKAVAYLLPYIEAEKADAGT MSMEG_4185|M.smegmatis_MC2_155 PLMDGMNVVGDLFGSGKMFLPQVVKSARVMKKAVAYLLPYIEAEKKPGDA Mb2148c|M.bovis_AF2122/97 HLLAGMKTVGELFGSGQMQLPFVLQSAEVMKAAVAYLEPHMERSDDDSGK Rv2124c|M.tuberculosis_H37Rv HLLAGMKTVGELFGSGQMQLPFVLQSAEVMKAAVAYLEPHMERSDDDSGK MLBr_01307|M.leprae_Br4923 NLLDGMKTVGELFGSGQMQLPFVLQSAEVMKAAVAYLEPHMEKSDCDFGK TH_0958|M.thermoresistible__bu HLLAGMKVVGELFGAGQMQLPFVLQSAEVMKAAVAHLEPHMEKSEDDSGK *: **:.**:***:*:* ** *::**.*** ***:* *.:* .. . MUL_0395|M.ulcerans_Agy99 TE---QDKTNGIIIMATVKGDVHDIGKNIVGVVLQCNNYTVVDLGVMVPA MMAR_4825|M.marinum_M TE---QDKTNGIIIMATVKGDVHDIGKNIVGVVLQCNNYTVVDLGVMVPA MAV_2379|M.avium_104 SG---SKDTNGTIVMATVKGDVHDIGKNIVGVVLQCNNFEVIDLGVMVPA Mvan_3474|M.vanbaalenii_PYR-1 SD---SKDTNGTIVMATVKGDVHDIGKNIVGVVLQCNNFEVIDLGVMVPA MAB_2129|M.abscessus_ATCC_1997 AGDSKSKDTNGTIVMATVKGDVHDIGKNIVGVVLQCNNFEVIDLGVMVPA Mflv_3053|M.gilvum_PYR-GCK TG---SKDTNGTIVMATVKGDVHDIGKNIVGVVLQCNNFEVIDLGVMVPA MSMEG_4185|M.smegmatis_MC2_155 ER------SNGTIIMATVKGDVHDIGKNIVGVVLQCNNYTVIDLGVMVPA Mb2148c|M.bovis_AF2122/97 ----------GRIVLATVKGDVHDIGKNLVDIVLSNNGYEVVNIGIKQPI Rv2124c|M.tuberculosis_H37Rv ----------GRIVLATVKGDVHDIGKNLVDIILSNNGYEVVNIGIKQPI MLBr_01307|M.leprae_Br4923 GL------AKGRIVLATVKGDVHDIGKNLVDIILSNNGYEVVNLGIKQPI TH_0958|M.thermoresistible__bu ----------GRIVLATVKGDVHDIGKNLVDIILTNNGYEVVNLGIKQPI * *::*************:*.::* *.: *:::*: * MUL_0395|M.ulcerans_Agy99 EKILAAAREYDADIIGLSGLITPSLDEMVNFAAAMERE--GMQIPLLIGG MMAR_4825|M.marinum_M EKILAAAREYDADIIGLSGLITPSLDEMVNFAAAMERE--GMQIPLLIGG MAV_2379|M.avium_104 QKILDAAKEHDADIIGLSGLITPSLDEMSNFAAEMERE--GLQIPLLIGG Mvan_3474|M.vanbaalenii_PYR-1 QKILDAAKEHNADIIGLSGLITPSLDEMANFAVEMERE--GLEIPLLIGG MAB_2129|M.abscessus_ATCC_1997 QKILDAAKEHDADIIGLSGLITPSLDEMANFAVEMERE--GLEIPLLIGG Mflv_3053|M.gilvum_PYR-GCK QKILDAAREHDADIIGLSGLITPSLDEMSNFAVEMERA--GLEIPLLIGG MSMEG_4185|M.smegmatis_MC2_155 QKILDAAKEHNADIIGLSGLITPSLDEMVNFAAEMERE--GMDIPLLIGG Mb2148c|M.bovis_AF2122/97 ATILEVAEDKSADVVGMSGLLVKSTVVMKENLEEMNTRGVAEKFPVLLGG Rv2124c|M.tuberculosis_H37Rv ATILEVAEDKSADVVGMSGLLVKSTVVMKENLEEMNTRGVAEKFPVLLGG MLBr_01307|M.leprae_Br4923 TNILEVAEDKSADVVGMSGLLVKSTVIMKENLEEMNTRGVAEKFPVLLGG TH_0958|M.thermoresistible__bu STILEVAEDKNADVVGMSGLLVKSTVVMKENLEEMNARGVAERFPVLLGG .** .*.: .**::*:***:. * * : *: . :*:*:** MUL_0395|M.ulcerans_Agy99 ATTSRAHTAVKVAPRRSGPVVWVKDASRSVPVAAALLDDKQRPGLLEATA MMAR_4825|M.marinum_M ATTSRAHTAVKVAPRRSGPVVWVKDASRSVPVAAALLDDKQRPGLLEATA MAV_2379|M.avium_104 ATTSRAHTAVKISPRRSGPVVWVKDASRSVPVAAALLDDKQRPALLEATE Mvan_3474|M.vanbaalenii_PYR-1 ATTSRAHTAVKIAPRRGGPVVWVKDASRSVPVAAALLDDRQRPALLEATE MAB_2129|M.abscessus_ATCC_1997 ATTSRAHTAVKISPRRKGPVVWVKDASRSVPVAAALLDDKQRPGLLEATE Mflv_3053|M.gilvum_PYR-GCK ATTSRAHTAVKISPRRSGPVVWVKDASRSVPVAAALLDDKQRPALLEATE MSMEG_4185|M.smegmatis_MC2_155 ATTSRAHTAVKVAPRRSGPVVWVKDASRSVPVAAALLDDKQRPALLEATE Mb2148c|M.bovis_AF2122/97 AALTRSYVENDLAEIYQGEVHYARDAFEGLKLMDTIMSAKRGEAPDENSP Rv2124c|M.tuberculosis_H37Rv AALTRSYVENDLAEIYQGEVHYARDAFEGLKLMDTIMSAKRGEAPDENSP MLBr_01307|M.leprae_Br4923 AALTRSYVENDLAEVYEGEVHYARDAFEGLKLMDTIMSAKRGEALAPGSP TH_0958|M.thermoresistible__bu AALTRGYVEDDLSEIYEGEVYYARDAFEGLRLMDRIMSEKRGGGPDPDSP *: :*.:. .:: * * :.:** ..: : ::. :: . : MUL_0395|M.ulcerans_Agy99 ADYAALR-----ERHSQKNERPMLTLEKARANRTPIDWDGYTPPLPAQGL MMAR_4825|M.marinum_M ADYAALR-----ERHSQKNERPMLTLEKARANRTPIDWDGYTPPLPAQGL MAV_2379|M.avium_104 KDYASLR-----ERHAQKNERPMVTLEKARANRTPIDWDGYTPPVPAIGA Mvan_3474|M.vanbaalenii_PYR-1 ADYASLR-----ERHAQKNERPMLTLEKARANRTPVEWDGYTPPVPAQGL MAB_2129|M.abscessus_ATCC_1997 KDYASLR-----ERHAQKNERPTLTLEKARANRTPVEWDGYTPPVPAQGL Mflv_3053|M.gilvum_PYR-GCK KDYASLR-----ERHAQKNDRPMLTLEKARANRTPIEWDGYTPPVPAQGV MSMEG_4185|M.smegmatis_MC2_155 KDYASLR-----ERHAQKNERPMVTLEKARANRTPIDWDGYTPPVPAQGL Mb2148c|M.bovis_AF2122/97 EAIKARE---KEAERKARHQRSKRIAAQRKAAEEPVEVPERSDVAADIEV Rv2124c|M.tuberculosis_H37Rv EAIKARE---KEAERKARHQRSKRIAAQRKAAEEPVEVPERSDVAADIEV MLBr_01307|M.leprae_Br4923 ESLAAEADRNKETERKARHERSKRIAVQRKAAEEPVEVPERSDVPSDVEV TH_0958|M.thermoresistible__bu EAIAARE---KEAERKARRARSKRIAAERKAKEEPVEVPARSDVAADVEV : .: :. *. : :* . *:: : . MUL_0395|M.ulcerans_Agy99 GVREFHDYDLAELREYIDWQPFFNAWEMKGRFPDILNNPATGEAARKLYN MMAR_4825|M.marinum_M GVREFHDYDLAELREYIDWQPFFNAWEMKGRFPDILNNPATGEAARKLYN MAV_2379|M.avium_104 GIREFQDYDLAELREYIDWQPFFNAWEMKGRFPDILNNPATGEAARKLYD Mvan_3474|M.vanbaalenii_PYR-1 GVREFKDYDLAELREYIDWQPFFNAWEMKGRFPDILNNPATGEAARKLYD MAB_2129|M.abscessus_ATCC_1997 GVREFLDYDLAEVREYIDWQPFFNAWEMKGRFPDILNNPATGEAARKLHD Mflv_3053|M.gilvum_PYR-GCK GVREFIDYDLAELREYIDWQPFFNAWEMKGRFPDILNNPATGEAARKLYN MSMEG_4185|M.smegmatis_MC2_155 GIREFENYDLSELRQYIDWQPFFNAWEMKGKFPDILNNPASGEAARKLYE Mb2148c|M.bovis_AF2122/97 PAPPFWGSRIVKGLAVADYTGLLDERALFLGQWGLRGQRGGEGPSYEDLV Rv2124c|M.tuberculosis_H37Rv PAPPFWGSRIVKGLAVADYTGLLDERALFLGQWGLRGQRGGEGPSYEDLV MLBr_01307|M.leprae_Br4923 PAPPFWGSRIIKGLAVADYTGFLDERALFLGQWGLRGVRGGAGPSYEDLV TH_0958|M.thermoresistible__bu PVPPFWGTRIVKGVAVADYAGTLDERALFLGQWGLRGARGGDGPSYEELV * . : : *: :: : .: . . .: : MUL_0395|M.ulcerans_Agy99 DAQEMLDTLIREKWLTAN-------GVIGFFPANAVG---DDIEVYTDET MMAR_4825|M.marinum_M DAQEMLDTLIREKWLTAN-------GVIGFFPANAVG---DDIEVYTDET MAV_2379|M.avium_104 DAQEMLDTLIKEKWLTAN-------AVIGFFPANAIGPGFEDIELYTDDT Mvan_3474|M.vanbaalenii_PYR-1 DAQEMLDTLIKEKWLTAN-------GVIGFFPANAS-PGGDDIVVYTDDT MAB_2129|M.abscessus_ATCC_1997 DAQQILDTLIKEKWLTAN-------GVIGFFPANAVGPGFEDIEVYTDDT Mflv_3053|M.gilvum_PYR-GCK DAQEMLDTLIKEKWLTAN-------GVIGFFCANAV---GDDIEVYTDDT MSMEG_4185|M.smegmatis_MC2_155 EAQEMLDTLIKEKWLTAN-------GVIGFFPANAVG---DDIEVYTDDT Mb2148c|M.bovis_AF2122/97 ETEGRPRLRYWLDRLSTDGILAHAAVVYGYFPAVSEG---NDIVVLTEPK Rv2124c|M.tuberculosis_H37Rv ETEGRPRLRYWLDRLSTDGILAHAAVVYGYFPAVSEG---NDIVVLTEPK MLBr_01307|M.leprae_Br4923 QTEGRPRLRYWLDRLSTYGVLAYAAVVYGYFPAVSED---NDIVVLAEPR TH_0958|M.thermoresistible__bu ETEGRPRLRYWLDRLATEGILAHAAVVYGYFPAVSQG---DDVIVLTEPE ::: . *:: * *:* * : :*: : :: MUL_0395|M.ulcerans_Agy99 RAEVLTTLHNLRQQGEHRAGIPNRSLGDFIAPKDTGLADYVGAFAVTAGL MMAR_4825|M.marinum_M RAEVLTTLHNLRQQGEHRAGIPNRSLGDFIAPKDTGLADYVGAFAVTAGL MAV_2379|M.avium_104 RTEVLTTLHNLRQQGEHRDGIPNRSLGDYVAPKETGHRDYIGAFAVTAGL Mvan_3474|M.vanbaalenii_PYR-1 RTEVLTTLHNLRQQGEHRSGIPNRSLGDFIAPKESGLRDYIGAFAVTAGL MAB_2129|M.abscessus_ATCC_1997 RTEVLTTLHNLRQQGEHRDGIPNRSLGDYIAPKETGLRDYIGAFAVTAGL Mflv_3053|M.gilvum_PYR-GCK RTEVLTTLYNLRQQGEHRDGIPNRSQGDFIAPKETGLRDYIGAFAVTAGL MSMEG_4185|M.smegmatis_MC2_155 RTEVLTTLRNLRQQGEHRDGIPNRSLGDFIAPKETGLADYIGAFAVTAGL Mb2148c|M.bovis_AF2122/97 PDAPVRYRFHFPRQQRGRFLCIADFIRSRELAAERGEVDVLPFQLVTMGQ Rv2124c|M.tuberculosis_H37Rv PDAPVRYRFHFPRQQRGRFLCIADFIRSRELAAERGEVDVLPFQLVTMGQ MLBr_01307|M.leprae_Br4923 PDAEQRYRFTFPRQQRGRFLCIADFIRSRDLATERSEVDVLPFQLVTMGQ TH_0958|M.thermoresistible__bu PDADERFRFTFPRQQRGRFLCIADFIRSRELAAKTGQVDVLPFQLVTMGQ : :* . * . . . . * : ** * MUL_0395|M.ulcerans_Agy99 GSQTKIVEFKEALDDYSAILLESIADRLAEAFAERMHQRVREEFWGYQPD MMAR_4825|M.marinum_M GSQTKIVEFKEALDDYSAILLESIADRLAEAFAERMHQRVREEFWGYQPD MAV_2379|M.avium_104 GSQEKIAEFKAALDDYSAILLESIADRLAEAFAERMHQRVRKEFWGYQPD Mvan_3474|M.vanbaalenii_PYR-1 GSQDKIMEFKAALDDYSAILLESLADRLAEAFAERMHERVRKEFWGYQPD MAB_2129|M.abscessus_ATCC_1997 GSQDKIMEFKADLDDYSAILLESIADRLAEAFAERMHQRVRTEFWGFQPD Mflv_3053|M.gilvum_PYR-GCK GSQAKIMEFKAALDDYSAILLESLADRLAEAFAERMHERVRTEFWGYQPD MSMEG_4185|M.smegmatis_MC2_155 GSAEKIAEFKADHDDYSAILLESLADRLAEAFAERMHQRVRTELWAYQPD Mb2148c|M.bovis_AF2122/97 PIADFANELFASNAYRDYLEVHGIGVQLTEALAEYWHRRIREELKFSGDR Rv2124c|M.tuberculosis_H37Rv PIADFANELFASNAYRDYLEVHGIGVQLTEALAEYWHRRIREELKFSGDR MLBr_01307|M.leprae_Br4923 PIADFVGELFVSNSYRDYLEVHGIGVQLTEALAEYWHRRIREELKFSGNR TH_0958|M.thermoresistible__bu PIADFANELFASNAYRDYLEVHGIGVQLTEAFAEYWHRRIREELRFG-DR *: . : :..:. :*:**:** *.*:* *: MUL_0395|M.ulcerans_Agy99 EQLDN-----EALIGERYVGIRPAPGYPACPEHTEKTTLFELMDVTKRTG MMAR_4825|M.marinum_M EQLDN-----EALIGERYVGIRPAPGYPACPEHTEKTTLFELMDVTKRTG MAV_2379|M.avium_104 EQLDN-----DALIDEKYRGIRPAPGYPACPEHTEKVTLWKLMDVKERTG Mvan_3474|M.vanbaalenii_PYR-1 EQLDN-----DALIGEKYVGIRPAPGYPACPEHTEKATLWKLMDVKERTG MAB_2129|M.abscessus_ATCC_1997 EQLDN-----EALIGEKYRGIRPAPGYPACPEHTEKVTLFDLLDVTKRTG Mflv_3053|M.gilvum_PYR-GCK EQLDN-----NALIAERYVGIRPAPGYPSCPEHTEKATLFGLLDATERTG MSMEG_4185|M.smegmatis_MC2_155 EELDN-----EALIAERYRGIRPAPGYPACPEHTEKATLFKLLDVTERTG Mb2148c|M.bovis_AF2122/97 AMAAEDPEAKEDYFKLGYRGARFAFGYGACPDLEDRAKMMALLEP-ERIG Rv2124c|M.tuberculosis_H37Rv AMAAEDPEAKEDYFKLGYRGARFAFGYGACPDLEDRAKMMALLEP-ERIG MLBr_01307|M.leprae_Br4923 TMSADDPEAVEDYFKLGYRGARFAFGYGACPDLEDRIKMMELLQP-ERIG TH_0958|M.thermoresistible__bu AMAAEDPESVEEYFKLGYRGARFSFGYGACPDLEDRKKMMELLEP-ERIG : : : * * * : ** :**: :: .: *:: :* * MUL_0395|M.ulcerans_Agy99 IELTESMAMWPGAAVSGWYFSHPQSQYFVVGRMAQDQVADYAKRKGWTLP MMAR_4825|M.marinum_M IELTESMAMWPGAAVSGWYFSHPQSQYFVVGRMAQDQVADYAKRKGWTLP MAV_2379|M.avium_104 IELTESMAMWPGAAVSGWYFSHPQSQYFVVGRLAQDQVADYAKRKGWTLA Mvan_3474|M.vanbaalenii_PYR-1 IELTESMAMWPGAAVSGWYFSHPQSQYFVVGRLAQDQVADYAKRKGWTLA MAB_2129|M.abscessus_ATCC_1997 IELTESMAMWPGAAVSGWYFAHPQSQYFVVGRLAQDQVADYAKRKGWTLQ Mflv_3053|M.gilvum_PYR-GCK IELTESMAMWPGAAVSGWYFSHPQSQYFVVGRLAQDQVADYARRKGWTLQ MSMEG_4185|M.smegmatis_MC2_155 IELTESMAMWPGAAVSGWYFSHPQSQYFVVGRLAQDQVADYARRKGWTLQ Mb2148c|M.bovis_AF2122/97 VTLSEELQLHPEQSTDAFVLHHPEAKYFNV-------------------- Rv2124c|M.tuberculosis_H37Rv VTLSEELQLHPEQSTDAFVLHHPEAKYFNV-------------------- MLBr_01307|M.leprae_Br4923 VTISEELQLHPEQSTDAFVLHHPAAKYFNV-------------------- TH_0958|M.thermoresistible__bu VVLSEELQLHPEQSTDAFVLHHPEAKYFNV-------------------- : ::*.: : * :...: : ** ::** * MUL_0395|M.ulcerans_Agy99 EAERWLGPNLGYNPED MMAR_4825|M.marinum_M EAERWLGPNLGYNPED MAV_2379|M.avium_104 EAERWLAPNLGYNPED Mvan_3474|M.vanbaalenii_PYR-1 EAERWLAPNLGYNPED MAB_2129|M.abscessus_ATCC_1997 EAERWLGPNLGYNPED Mflv_3053|M.gilvum_PYR-GCK EAERWLAPNLGYNPED MSMEG_4185|M.smegmatis_MC2_155 EAERWLAPNLGYNPED Mb2148c|M.bovis_AF2122/97 ---------------- Rv2124c|M.tuberculosis_H37Rv ---------------- MLBr_01307|M.leprae_Br4923 ---------------- TH_0958|M.thermoresistible__bu ----------------