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M. avium 104 MAV_2379 (metH)

annotation: B12-dependent methionine synthase
coordinates: 2398182 - 2401955
length: 1257

VTAPVTTPASDSFAPNIRPDCTDELTAALRQRIMVIDGAMGTAIQRDRPDEAGYRGERFKDWPSDLVGNN
DLLNLTQPQIIEGIHREYLEAGADILETNTFNANAISLSDYGMEELSYELNYAGAALARKAADEFSTPDK
PRYVAGALGPTSRTASISPDVNDPGARNVTYDELVAAYLEAANGLVDGGVDLLIVETIFDTLNAKAAVFA
LETLFEQRGRRWPVIISGTITDASGRTLSGQVTEAFWNSIRHAKPIAVGLNCALGAPEMRPYIAEVSRIA
DTFVSCYPNAGLPNAFGEYDESPERQASYIADFAEAGLVNIVGGCCGTAPPHIAEIAKVVEGKPPREVPQ
IPVATRLSGLEPLNITDDSLFVNIGERTNITGSARFRNLIKAEDYDTALSVALQQVEVGAQVIDINMDEG
MIDGVAAMDRFTRLIAAEPDISRVPVMIDSSKWEVIEAGLKNVQGKPIVNSISLKEGEEKFVREARLCRK
YGAAVVVMAFDEQGQADNLERRKQICARAYRVLTEEVGFPPEDIIFDPNCFALATGIEEHATYGIDFIEA
CAWIKENLPGVHLSGGISNVSFSFRGNNPVREAIHSVFLFHAIKAGLDMGIVNAGALVPYDSIDPELRDR
IEDVVLNRREDAAERLLEIAERFNKSADASEDSAAAEWRGLPVRERITHALVKGIDAHVDEDTEELRAEI
AAAGGRPIEVIEGPLMDGMNVVGDLFGSGKMFLPQVVKSARVMKKAVAYLLPFIEAEKEESGVSGSKDTN
GTIVMATVKGDVHDIGKNIVGVVLQCNNFEVIDLGVMVPAQKILDAAKEHDADIIGLSGLITPSLDEMSN
FAAEMEREGLQIPLLIGGATTSRAHTAVKISPRRSGPVVWVKDASRSVPVAAALLDDKQRPALLEATEKD
YASLRERHAQKNERPMVTLEKARANRTPIDWDGYTPPVPAIGAGIREFQDYDLAELREYIDWQPFFNAWE
MKGRFPDILNNPATGEAARKLYDDAQEMLDTLIKEKWLTANAVIGFFPANAIGPGFEDIELYTDDTRTEV
LTTLHNLRQQGEHRDGIPNRSLGDYVAPKETGHRDYIGAFAVTAGLGSQEKIAEFKAALDDYSAILLESI
ADRLAEAFAERMHQRVRKEFWGYQPDEQLDNDALIDEKYRGIRPAPGYPACPEHTEKVTLWKLMDVKERT
GIELTESMAMWPGAAVSGWYFSHPQSQYFVVGRLAQDQVADYAKRKGWTLAEAERWLAPNLGYNPED
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. avium 104MAV_2379metH-100% (1257)B12-dependent methionine synthase
M. avium 104MAV_1715mmuM4e-1025.89% (309) homocysteine methyltransferase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2148cmetH1e-16634.57% (1241) 5-methyltetrahydrofolate--homocystein methyltransferase
M. gilvum PYR-GCKMflv_3053metH0.091.33% (1245) B12-dependent methionine synthase
M. tuberculosis H37RvRv2124cmetH1e-16634.49% (1241) 5-methyltetrahydrofolate--homocystein methyltransferase
M. leprae Br4923MLBr_01307metH1e-16232.77% (1242) 5-methyltetrahydrofolate-homocysteine methyltransferase
M. abscessus ATCC 19977MAB_2129metH0.091.59% (1248) B12-dependent methionine synthase
M. marinum MMMAR_4825metH0.090.29% (1246) 5-methyltetrahydrofolate--homocysteine methyltransferase, MetH
M. smegmatis MC2 155MSMEG_4185metH0.090.62% (1248) B12-dependent methionine synthase
M. thermoresistible (build 8)TH_0958metH1e-16232.96% (1262) Probable 5-methyltetrahydrofolate--homocystein
M. ulcerans Agy99MUL_0395metH0.090.05% (1246) B12-dependent methionine synthase
M. vanbaalenii PYR-1Mvan_3474metH0.092.44% (1243) B12-dependent methionine synthase

CLUSTAL 2.0.9 multiple sequence alignment


MAV_2379|M.avium_104                ------------------------MTAPVTTPASDSFAPNIRPDCTDELT
Mvan_3474|M.vanbaalenii_PYR-1       ----------------------------MNSADPNIWEPNIRPDCTDELK
MAB_2129|M.abscessus_ATCC_1997      ---------------------------------MTNLQPNVRPDCTEALT
Mflv_3053|M.gilvum_PYR-GCK          --------------------------MEGAHVNAVEFEPNIRPDCTEELT
MMAR_4825|M.marinum_M               ---------------------------------MSAFEPNIRPDCTDALT
MUL_0395|M.ulcerans_Agy99           MWVERRCNGSPVPRRYPPRSAESRTPSATEGINVSAFEPNIRPDCTDALT
MSMEG_4185|M.smegmatis_MC2_155      ----------------------------MNAVRSETLAPNIRPDCTDALT
Mb2148c|M.bovis_AF2122/97           ------------------------------------MTAADKHLYDTDLL
Rv2124c|M.tuberculosis_H37Rv        ------------------------------------MTAADKHLYDTDLL
MLBr_01307|M.leprae_Br4923          ----------------------------------MRVTAANQHQYDTDLL
TH_0958|M.thermoresistible__bu      ------------------------MKQVAHDDYAVGVTPVDTAVYDTDLL
                                                                          .         * 

MAV_2379|M.avium_104                AALRQRIMVIDGAMGTAIQRDRPDEAGYRGERFKDWPSDLVGNNDLLNLT
Mvan_3474|M.vanbaalenii_PYR-1       VALGRRIVVIDGAMGTAIQRDRPDEAGYRGERFKDWPSDLVGNNDLLTLT
MAB_2129|M.abscessus_ATCC_1997      AALEQRILVIDGAMGTAIQRDRPDEAGYRGERFADWPSDLVGNNDLLTLT
Mflv_3053|M.gilvum_PYR-GCK          AALRERIMVIDGAMGTAIQRDRPDEAGYRGDRFTEWPTALQGNNDLLNLT
MMAR_4825|M.marinum_M               AALGQRIMVIDGAMGTAIQRDRPDEAGYRGERFKDWPSDLVGNNDLLSLT
MUL_0395|M.ulcerans_Agy99           ATLGQRIMVIDGAMGTAIQRDRPDEAGYRGERFKDWPSDLVGNNDLLSLT
MSMEG_4185|M.smegmatis_MC2_155      AALRQRILVIDGAMGTAIQRDRPDEAGYRGERFKDWPSDLVGNNDLLNLT
Mb2148c|M.bovis_AF2122/97           DVLSQRVMVGDGAMGTQLQAADLTLDDFRG---------LEGCNEILNET
Rv2124c|M.tuberculosis_H37Rv        DVLSQRVMVGDGAMGTQLQAADLTLDDFRG---------LEGCNEILNET
MLBr_01307|M.leprae_Br4923          ETLAQRVMVGDGAMGTQLQDAELTLDDFRG---------LEGCNEILNET
TH_0958|M.thermoresistible__bu      ETLSRRVMVGDGAMGTQLQAADLTLDDFNG---------LEGCNEILNET
                                     .* .*::* ****** :*       .:.*         * * *::*. *

MAV_2379|M.avium_104                QPQIIEGIHREYLEAGADILETNTFNANAISLSDYGMEELSYELNYAGAA
Mvan_3474|M.vanbaalenii_PYR-1       QPQIIEGIHREYLEAGADILETNTFNANAVSLSDYGMEKLSYELNYAGAA
MAB_2129|M.abscessus_ATCC_1997      QPHIIEGIHREYLEAGADILETNTFNANAVSLSDYGMEELSYELNYAGAA
Mflv_3053|M.gilvum_PYR-GCK          QPQIIEAIHREYLDAGADILETNTFNANAISLSDYDMTDLAYELNYAGAA
MMAR_4825|M.marinum_M               QPQIIEGIHREYLQAGADILETNTFNANAVSLSDYDMAELAYELNYAGAA
MUL_0395|M.ulcerans_Agy99           QPQIIEGIHREYLQAGADILETNTFNANAVSLSDYDMAELAYELNYAGAA
MSMEG_4185|M.smegmatis_MC2_155      QPHIIEAIHREYLDAGADLLETNTFNANAVSLSDYGMQELAYELNYAGAA
Mb2148c|M.bovis_AF2122/97           RPDVLETIHRNYFEAGADAVETNTFGCNLSNLGDYDIADRIRDLSQKGTA
Rv2124c|M.tuberculosis_H37Rv        RPDVLETIHRNYFEAGADAVETNTFGCNLSNLGDYDIADRIRDLSQKGTA
MLBr_01307|M.leprae_Br4923          RPDVLETIHRRYFEAGADLVETNTFGCNLSNLGDYDIADKIRDLSQRGTV
TH_0958|M.thermoresistible__bu      RPDVIAEIHRNYLAAGADAVETNTFGCNLSNLGDYDIADKIRSLSEQGTA
                                    :*.::  ***.*: **** :*****..*  .*.**.: .   .*.  *:.

MAV_2379|M.avium_104                LARKAADEFSTPDKPRYVAGALGPTSRTASISPDVNDPGARNVTYDELVA
Mvan_3474|M.vanbaalenii_PYR-1       LARKACDEFSTPDKPRYVAGALGPTTRTASISPDVNDPGARNVSYDQLVA
MAB_2129|M.abscessus_ATCC_1997      LARVAADEYSTPAKPRYVAGALGPTTRTASISPDVNDPGARNVSYDQLVA
Mflv_3053|M.gilvum_PYR-GCK          LARKAADEYSTADKPRYVAGAIGPTTRTASISPDVNDPGARNVSYDQLVA
MMAR_4825|M.marinum_M               LARAAADEFSTPEKPRYVAGALGPTTRTASISPDVNDPGARNVSYDQLVA
MUL_0395|M.ulcerans_Agy99           LARAAADEFSTPEKPRYVAGALGPTTRTASISPDVNDPGARNVSYDQLVA
MSMEG_4185|M.smegmatis_MC2_155      LARAACDEYSTPDKPRYVAGALGPTTRTASISPDVNDPGARNVSYDQLAE
Mb2148c|M.bovis_AF2122/97           IARRVADELGSPDRKRYVLGSMGPGTKLPTLG---------HTEYAVIRD
Rv2124c|M.tuberculosis_H37Rv        IARRVADELGSPDRKRYVLGSMGPGTKLPTLG---------HTEYAVIRD
MLBr_01307|M.leprae_Br4923          IARRVADELTTPDHKRYVLGSMGPGTKLPTLG---------HTEYRVVRD
TH_0958|M.thermoresistible__bu      IARRVADEMSTPDHRRYVLAAMGPGTKLPTLG---------HTEFGVIRD
                                    :** ..**  :. : *** .::** :: .::.         :. :  :  

MAV_2379|M.avium_104                AYLEAANGLVDGGVDLLIVETIFDTLNAKAAVFALETLFEQRGRRWPVII
Mvan_3474|M.vanbaalenii_PYR-1       AYLDAASGLVDGGADLLIVETIFDTLNAKAAVFAIETLFEDRGRRWPVII
MAB_2129|M.abscessus_ATCC_1997      AYLEAANGLVDGGADIILVETIFDSLNAKAAVFAIETLFEQRGRRWPIII
Mflv_3053|M.gilvum_PYR-GCK          AYLEAANGLVDGGSDLIMIETIFDSLNAKAAVFAVETLFEERGRRWPVII
MMAR_4825|M.marinum_M               AYLEAANGLVDGGADIIIIETIFDSLNAKAAVFAVETLFEDRGRRWPVII
MUL_0395|M.ulcerans_Agy99           AYLEAANGLVDGGADIIIIETIFDSLNAKAAVFAVETLFEDRGRRWPVII
MSMEG_4185|M.smegmatis_MC2_155      AYLEAARGLVDGGADLIIVETIFDTLNAKAAIFAIETLFEERGRRWPVII
Mb2148c|M.bovis_AF2122/97           AYTEAALGMLDGGADAILVETCQDLLQLKAAVLGSRRAMTRAGRHIPVFA
Rv2124c|M.tuberculosis_H37Rv        AYTEAALGMLDGGADAILVETCQDLLQLKAAVLGSRRAMTRAGRHIPVFA
MLBr_01307|M.leprae_Br4923          AYTESALGMLDGGADAVLVETCQDLLQLKAAVLGSRRAMTQAGRHIPVFV
TH_0958|M.thermoresistible__bu      AYIEAALGMLDGGADAILIETCQDLLQLKAAVLGARRAMARAGRHIPIIT
                                    ** ::* *::*** * :::**  * *: ***::. .  :   **: *:: 

MAV_2379|M.avium_104                SGTITDASGRTLSGQVTEAFWNSIRHAKPIAVGLNCALGAPEMRPYIAEV
Mvan_3474|M.vanbaalenii_PYR-1       SGTITDASGRTLSGQVTEAFWNSVRHARPLAVGLNCALGAPEMRPYLAEM
MAB_2129|M.abscessus_ATCC_1997      SGTITDASGRTLSGQVTEAFWNAIRHARPIAVGLNCALGAPEMRPYIAEM
Mflv_3053|M.gilvum_PYR-GCK          SGTITDASGRTLSGQVTEAFWNAIRHAKPLAVGLNCALGAPEMRPYIAEV
MMAR_4825|M.marinum_M               SGTITDASGRTLSGQVTEAFWNAIRHAKPIAVGLNCALGAPEMRPYIAEM
MUL_0395|M.ulcerans_Agy99           SGTITDASGRTLSGQVTEAFWNAIRHAKPIAVGLNCALGAPEMRPYIAEM
MSMEG_4185|M.smegmatis_MC2_155      SGTITDASGRTLSGQVTEAFWNSIRHAQPLAVGLNCALGAPEMRPYIAEM
Mb2148c|M.bovis_AF2122/97           H-VTVETTGTMLLGSEIGAALTAVEPLGVDMIGLNCATGPAEMSEHLRHL
Rv2124c|M.tuberculosis_H37Rv        H-VTVETTGTMLLGSEIGAALTAVEPLGVDMIGLNCATGPAEMSEHLRHL
MLBr_01307|M.leprae_Br4923          H-VTVETTGTMLLGSEIGAALAAVEPLGVDMIGLNCATGPAEMSEHLRHL
TH_0958|M.thermoresistible__bu      H-VTVETTGTMLLGSEIGAALTAIEPLGVDVIGLNCATGPAEMSEHLRYL
                                      . .:::*  * *.   *   ::.      :***** *..**  ::  :

MAV_2379|M.avium_104                SRIADTFVSCYPNAGLPNAFG---EYDESPERQASYIADFAEAGLVNIVG
Mvan_3474|M.vanbaalenii_PYR-1       SRIADTFVSCYPNAGLPNAFG---EYDESPTRQAGYVAEFAEAGLVNLVG
MAB_2129|M.abscessus_ATCC_1997      SRIADTFVSCYPNAGLPNAFG---EYDESPEHQAGYLAEFAEAGLVNLVG
Mflv_3053|M.gilvum_PYR-GCK          ARIADTFVSCYPNAGLPNAFG---EYDESPERQASYIAEFAEAGLVNLVG
MMAR_4825|M.marinum_M               ARIADTFVSCYPNAGLPNAFG---EYDETPEHQAGYIAEFADAGLVNLVG
MUL_0395|M.ulcerans_Agy99           ARIADTFVSCYPNAGLPNAFG---EYDETPEHQAGYIAEFADAGLVNLVG
MSMEG_4185|M.smegmatis_MC2_155      SRIADTFVSCYPNAGLPNAFG---EYDESPKRQASYVEEFAEAGFVNLVG
Mb2148c|M.bovis_AF2122/97           SRHARIPVSVMPNAGLPVLGAKGAEYPLLPDELAEALAGFIAEFGLSLVG
Rv2124c|M.tuberculosis_H37Rv        SRHARIPVSVMPNAGLPVLGAKGAEYPLLPDELAEALAGFIAEFGLSLVG
MLBr_01307|M.leprae_Br4923          SKHARIPVSVMPNAGLPVLGAKGAEYPLQPDELAEALAGFIAEFGLSLVG
TH_0958|M.thermoresistible__bu      SRHSRLPVSVMPNAGLPVLGPDGAVYPLRPDELAEALAGFVSEFGLSLVG
                                    :: :   **  ******        *   * . *  :  *     :.:**

MAV_2379|M.avium_104                GCCGTAPPHIAEIAKVVEG----KPPREVPQIPVATRLSGLEPLN-ITDD
Mvan_3474|M.vanbaalenii_PYR-1       GCCGTTPAHIAEIARVVDG----KPPRKVPEIPVATRLAGLEPLN-ITDD
MAB_2129|M.abscessus_ATCC_1997      GCCGTAPAHIAEIAKVVEG----VKPRDVPSIDVATRLSGLEPLN-ITDD
Mflv_3053|M.gilvum_PYR-GCK          GCCGTAPPHIAEIAKVVDG----KTPRELPQIPVATRLSGLEPLN-INDE
MMAR_4825|M.marinum_M               GCCGTAPPHIAEIAKVVEG----KAPRELPEIPVATRLSGLEPLN-ISDD
MUL_0395|M.ulcerans_Agy99           GCCGTAPPHIAEIAKVVEG----KAPRELPEIPVATRLSGLEPLN-ITDD
MSMEG_4185|M.smegmatis_MC2_155      GCCGTTPAHIAEIAKVVEG----KPPRQVPEIPVATRLSGLEPLN-IDED
Mb2148c|M.bovis_AF2122/97           GCCGTTPAHIREVAAAVAN-----IKRPERQVSYEPSVSSLYTAIPFAQD
Rv2124c|M.tuberculosis_H37Rv        GCCGTTPAHIREVAAAVAN-----IKRPERQVSYEPSVSSLYTAIPFAQD
MLBr_01307|M.leprae_Br4923          GCCGTTPDHIREVAAAVARCNDGTVPRGERHVTYEPSVSSLYTAIPFAQK
TH_0958|M.thermoresistible__bu      GCCGTTPEHIRQVVDAVSG-----VQRAGRQISYEPGLSSLYTSTPFAQD
                                    *****:* ** ::. .*         *    :   . ::.* .   : :.

MAV_2379|M.avium_104                SLFVNIGERTNITGSARFRNLIKAEDYDTALSVALQQVEVGAQVIDINMD
Mvan_3474|M.vanbaalenii_PYR-1       SLFVNIGERTNITGSARFRNLIKAEDYDTALSVALQQVEVGAQVIDINMD
MAB_2129|M.abscessus_ATCC_1997      SLFVNIGERTNITGSARFRNLIKAEDYDTALSVALQQVEVGAQVIDINMD
Mflv_3053|M.gilvum_PYR-GCK          SLFVNIGERTNITGSARFRNLIKAEDYDTALSVALQQVEVGAQVIDINMD
MMAR_4825|M.marinum_M               SLFVNIGERTNITGSARFRNLIKAEDYDTALSVALQQVEVGAQVIDINMD
MUL_0395|M.ulcerans_Agy99           SLFENIGERTNITGSARFRNLIKAEDYDTALSVALQQVEVGAQVIDINMD
MSMEG_4185|M.smegmatis_MC2_155      SLFVNIGERTNITGSARFRNLIKAEDYDTALSVALQQVEVGAQVIDINMD
Mb2148c|M.bovis_AF2122/97           ASVLVIGERTNANGSKGFREAMIAEDYQKCLDIAKDQTRDGAHLLDLCVD
Rv2124c|M.tuberculosis_H37Rv        ASVLVIGERTNANGSKGFREAMIAEDYQKCLDIAKDQTRDGAHLLDLCVD
MLBr_01307|M.leprae_Br4923          PSVLMIGERTNANGSKVFREAMIAEDYQKCLDIAKDQTRGGAHLLDLCVD
TH_0958|M.thermoresistible__bu      ASVLMIGERTNANGSKAFREAMIAEDYQRCLDIAKEQTRDGAHLLDLCVD
                                    . .  ****** .**  **: : ****: .*.:* :*.. **:::*: :*

MAV_2379|M.avium_104                EGMIDGVAAMDRFTRLIAAEPDISRVPVMIDSSKWEVIEAGLKNVQGKPI
Mvan_3474|M.vanbaalenii_PYR-1       EGMIDGVAAMDRFTKLIAAEPDISRVPVMIDSSKWEVIEAGLKNVQGKPI
MAB_2129|M.abscessus_ATCC_1997      EGMIDGVAAMDRFTKLIAAEPDISRVPVMIDSSKWEVIEAGLKNVQGKPI
Mflv_3053|M.gilvum_PYR-GCK          EGMIDGVAAMDRFTKLIASEPDISRVPVMIDSSKWEVIEAGLKNVQGKPI
MMAR_4825|M.marinum_M               EGMIDGVAAMDRFTKLIAAEPDISRVPVMIDSSKWEVIEAGLKNVQGKPI
MUL_0395|M.ulcerans_Agy99           EGMIDGVAAMDRFTKLIAAEPDISRVPVMIDSSKWEVIEAGLKNVQGKPI
MSMEG_4185|M.smegmatis_MC2_155      EGMIDGVAAMDRFTKLIASEPDISRVPVMIDSSKWEVIEAGLKNVQGKPI
Mb2148c|M.bovis_AF2122/97           YVGRDGVADMKALASRLAT---SSTLPIMLDSTETAVLQAGLEHLGGRCA
Rv2124c|M.tuberculosis_H37Rv        YVGRDGVADMKALASRLAT---SSTLPIMLDSTETAVLQAGLEHLGGRCA
MLBr_01307|M.leprae_Br4923          YVGRNGVADMKALAGRLAT---VSTLPIMLDSTEIPVLQAGLEHLGGRCV
TH_0958|M.thermoresistible__bu      YVGRDGVADMKALASRLAT---ASTLPIMLDSTETDVLRAGLEHLGGRCA
                                        :*** *. ::  :*:    * :*:*:**::  *:.***::: *:  

MAV_2379|M.avium_104                VNSISLKEG---EEKFVREARLCRKYGAAVVVMAFDEQGQADNLERRKQI
Mvan_3474|M.vanbaalenii_PYR-1       VNSISMKEG---EEKFIREARLCRKYGAAVVVMAFDEQGQADNLERRKQI
MAB_2129|M.abscessus_ATCC_1997      VNSISMKEG---EEKFIREARLCRKYGAAVVVMAFDEKGQADNLERRKEI
Mflv_3053|M.gilvum_PYR-GCK          VNSISMKEG---EEKFIREAQLCRKYGAAVVVMAFDEQGQADNLERRKEI
MMAR_4825|M.marinum_M               VNSISMKEG---EEKFVREARLCRKYGAAVVVMAFDEKGQADNLERRKEI
MUL_0395|M.ulcerans_Agy99           VNSISMKEG---EEKFVREARLCRKYGAAVVVMAFDEKGQADNLERRKEI
MSMEG_4185|M.smegmatis_MC2_155      VNSISLKEG---EEKFVREARLCRKYGAAVVVMAFDEQGQADNLERRKQI
Mb2148c|M.bovis_AF2122/97           INSVNYEDGDGPESRFAKTMALVAEHGAAVVALTIDEEGQARTAQKKVEI
Rv2124c|M.tuberculosis_H37Rv        INSVNYEDGDGPESRFAKTMALVAEHGAAVVALTIDEEGQARTAQKKVEI
MLBr_01307|M.leprae_Br4923          INSVNYEDGDGPESRFVKTMELVAEHGAAVVALTIDEQGQARTVEKKVEV
TH_0958|M.thermoresistible__bu      VNSVNYEDGAGPESRFHKTMELVAEHGAAVVALTIDEEGQARTAEHKVAI
                                    :**:. ::*   *.:* :   *  ::*****.:::**:*** . :::  :

MAV_2379|M.avium_104                CARAYRVLTEEVGFPPEDIIFDPNCFALATGIEEHATYGIDFIEACAWIK
Mvan_3474|M.vanbaalenii_PYR-1       CGRAYRILTEEVGFPAEDIIFDPNCFALATGIEEHASYGIDFIEACAWIK
MAB_2129|M.abscessus_ATCC_1997      CGRAYRILTEEVGFPAEDIIFDPNCFALATGIEEHATYGIDFIEACAWIK
Mflv_3053|M.gilvum_PYR-GCK          CGRAYRILTEKVGFPAEDIIFDPNCFALATGIEEHATYGIDFIEACAWIK
MMAR_4825|M.marinum_M               CGRAYRILTEEVGFPAEDIIFDPNCFALATGIEEHATYGIDFIEACAWIK
MUL_0395|M.ulcerans_Agy99           CGRAYRILTEEVGFPAEDIIFDPNCFALATGIEEHATYGIDFIEACAWIK
MSMEG_4185|M.smegmatis_MC2_155      CGRAYKTLTEEVGFPAEDIIFDPNCFALATGIEEHATYGIDFIEACRWIK
Mb2148c|M.bovis_AF2122/97           AERLINDITGNWGVDESSILIDTLTFTIATGQEESRRDGIETIEAIRELK
Rv2124c|M.tuberculosis_H37Rv        AERLINDITGNWGVDESSILIDTLTFTIATGQEESRRDGIETIEAIRELK
MLBr_01307|M.leprae_Br4923          AERLINDITSNWGVDKSAILIDCLTFTIATGQEESRKDGIETIDAIRELK
TH_0958|M.thermoresistible__bu      AERLIEDITTNWGVEKSSILVDCLTFTICTGQEESRRDGIETIEAIRELK
                                    . *  . :* : *.  . *:.*   *::.** **    **: *:*   :*

MAV_2379|M.avium_104                ENLPGVHLSGGISNVSFSFRGNNPVREAIHSVFLFHAIKAGLDMGIVNAG
Mvan_3474|M.vanbaalenii_PYR-1       ENLPGVHISGGISNVSFSFRGNNPVREAIHAVFLFHAIKAGLDMGIVNAG
MAB_2129|M.abscessus_ATCC_1997      ENLPGVHISGGISNVSFSFRGNNPVREAIHAVFLFHAIKAGLDMGIVNAG
Mflv_3053|M.gilvum_PYR-GCK          ENLPGVHISGGISNVSFSFRGNNPVREAIHAVFLFHAIKAGLDMGIVNAG
MMAR_4825|M.marinum_M               ENLPGVHISGGISNVSFSFRGNNPVREAIHAVFLFHAIKAGLDMGIVNAG
MUL_0395|M.ulcerans_Agy99           ENLPGVHISGGISNVSFSFRGNNPVREAIHAVFLFHAIKAGLDMGIVNAG
MSMEG_4185|M.smegmatis_MC2_155      ENLPGVHISGGISNVSFSFRGNNPVREAIHAVFLFHAIKAGLDMGIVNAG
Mb2148c|M.bovis_AF2122/97           KRHPDVQTTLGLSNISFGLN--PAARQVLNSVFLHECQEAGLDSAIVHAS
Rv2124c|M.tuberculosis_H37Rv        KRHPDVQTTLGLSNISFGLN--PAARQVLNSVFLHECQEAGLDSAIVHAS
MLBr_01307|M.leprae_Br4923          KRHPAVQTTLGLSNISFGLN--PSARQVLNSVFLHECQEAGLDSAIVHAS
TH_0958|M.thermoresistible__bu      KRHPDVQTTLGLSNISFGLN--PAARQVLNSVFLHECREAGLDSAIVHAS
                                    :. * *: : *:**:**.:.   ..*:.:::***... :**** .**:*.

MAV_2379|M.avium_104                ALVPYDSIDPELRDRIEDVVLNRREDAAERLLEIAERFNKSADAS--EDS
Mvan_3474|M.vanbaalenii_PYR-1       ALVPYDSIDPELRDRIEDVVLNRREDAAERLLEIAERFN-SKGET--EDA
MAB_2129|M.abscessus_ATCC_1997      ALVPYDSIDSELRDRIEDVVLNRRADAAERLLEIAERFNSTENSGGGDDR
Mflv_3053|M.gilvum_PYR-GCK          ALVPYDSIDPELRDRIEDVVLNRRADAAERLLEIAERFN-KADKG--EDP
MMAR_4825|M.marinum_M               ALVPYDSIDPELRERIEDVVLNRREDAAERLLEIAERFN-TKGKS--EDP
MUL_0395|M.ulcerans_Agy99           ALVPYDSIDPELRERIEDVVLNRREDAAERLLEIAERFN-TKGKP--EDP
MSMEG_4185|M.smegmatis_MC2_155      ALVPYDSIDPELRERIEDVVLNRREDAAERLLEIAERFN-SKDKG--EDP
Mb2148c|M.bovis_AF2122/97           KILPMNRIPEEQRNVALDLVYDRRREDYDPLQELMRLFEGVSAASS-KED
Rv2124c|M.tuberculosis_H37Rv        KILPMNRIPEEQRNVALDLVYDRRREDYDPLQELMRLFEGVSAASS-KED
MLBr_01307|M.leprae_Br4923          KILPINRIPEEQRQAALDLVYDRRREGYDPLQKLMWLFKGVSSPSS-KET
TH_0958|M.thermoresistible__bu      KILPMNRIDEKQREVALDLIYDRRREGYDPLQELMTMFEGVSTADS-KES
                                     ::* : *  : *:   *:: :** :  : * ::   *:        .: 

MAV_2379|M.avium_104                AAAEWRGLPVRERITHALVKGIDAHVDEDTEELRAEIAAAGGRPIEVIEG
Mvan_3474|M.vanbaalenii_PYR-1       GVAEWRSLPVRERITHALVKGIDAHVDDDTEELRAEIADAGGRPIEVIEG
MAB_2129|M.abscessus_ATCC_1997      AAQEWRSLPVRERITHALVKGIDAHVDDDTEELRAEIAAAGGRPIEVIEG
Mflv_3053|M.gilvum_PYR-GCK          QAAEWRSLPVRERITHALVKGIDAHVDDDTEELRAEIEAAGGRPIEVIEG
MMAR_4825|M.marinum_M               AAAEWRSLPVRERITHALVKGIDAHVDADTEELRAEIAAAGGRPIEVIEG
MUL_0395|M.ulcerans_Agy99           AAAEWRSLPVRERITHALVKGIDAHVDADTEELRAEIAAAGGRLIEVIEG
MSMEG_4185|M.smegmatis_MC2_155      AAAEWRSLPVRERITHALVKGIDAHVDDDTEELRAEIAAAGGRPIEVIEG
Mb2148c|M.bovis_AF2122/97           RLAELAGLPLFERLAQRIVDGERNGLDADLDEAMTQKP-----PLQIINE
Rv2124c|M.tuberculosis_H37Rv        RLAELAGLPLFERLAQRIVDGERNGLDADLDEAMTQKP-----PLQIINE
MLBr_01307|M.leprae_Br4923          REAELAKLPLFDRLAQRIVDGERNGLDVDLDEAMTQKP-----PLAIINE
TH_0958|M.thermoresistible__bu      RAAELAKLPVLERLAQRIVDGERNGLEADLDEAMTIKP-----PLEIINE
                                       *   **: :*::: :*.*    :: * :*  :         : :*: 

MAV_2379|M.avium_104                PLMDGMNVVGDLFGSGKMFLPQVVKSARVMKKAVAYLLPFIEAEKEESGV
Mvan_3474|M.vanbaalenii_PYR-1       PLMDGMNVVGDLFGAGKMFLPQVVKSARVMKKAVAYLLPFIEAEKAENGT
MAB_2129|M.abscessus_ATCC_1997      PLMDGMNVVGDLFGSGKMFLPQVVKSARVMKKAVAYLLPFIEAEKEDNGT
Mflv_3053|M.gilvum_PYR-GCK          PLMDGMNVVGDLFGSGKMFLPQVVKSARVMKKAVAYLLPYIEAEKADAGT
MMAR_4825|M.marinum_M               PLMDGMNVVGDLFGAGKMFLPQVVKSARVMKKAVAYLLPFIEAEKAQSGS
MUL_0395|M.ulcerans_Agy99           PLMDGMNVVGDLFGAGKMFLPQVVKSARVMKKAVAYLLPFIEAEKAQSGS
MSMEG_4185|M.smegmatis_MC2_155      PLMDGMNVVGDLFGSGKMFLPQVVKSARVMKKAVAYLLPYIEAEKKPGDA
Mb2148c|M.bovis_AF2122/97           HLLAGMKTVGELFGSGQMQLPFVLQSAEVMKAAVAYLEPHMERSDDDSGK
Rv2124c|M.tuberculosis_H37Rv        HLLAGMKTVGELFGSGQMQLPFVLQSAEVMKAAVAYLEPHMERSDDDSGK
MLBr_01307|M.leprae_Br4923          NLLDGMKTVGELFGSGQMQLPFVLQSAEVMKAAVAYLEPHMEKSDCDFGK
TH_0958|M.thermoresistible__bu      HLLAGMKVVGELFGAGQMQLPFVLQSAEVMKAAVAHLEPHMEKSEDDSGK
                                     *: **:.**:***:*:* ** *::**.*** ***:* *.:* ..   . 

MAV_2379|M.avium_104                SG---SKDTNGTIVMATVKGDVHDIGKNIVGVVLQCNNFEVIDLGVMVPA
Mvan_3474|M.vanbaalenii_PYR-1       SD---SKDTNGTIVMATVKGDVHDIGKNIVGVVLQCNNFEVIDLGVMVPA
MAB_2129|M.abscessus_ATCC_1997      AGDSKSKDTNGTIVMATVKGDVHDIGKNIVGVVLQCNNFEVIDLGVMVPA
Mflv_3053|M.gilvum_PYR-GCK          TG---SKDTNGTIVMATVKGDVHDIGKNIVGVVLQCNNFEVIDLGVMVPA
MMAR_4825|M.marinum_M               TE---QDKTNGIIIMATVKGDVHDIGKNIVGVVLQCNNYTVVDLGVMVPA
MUL_0395|M.ulcerans_Agy99           TE---QDKTNGIIIMATVKGDVHDIGKNIVGVVLQCNNYTVVDLGVMVPA
MSMEG_4185|M.smegmatis_MC2_155      ER------SNGTIIMATVKGDVHDIGKNIVGVVLQCNNYTVIDLGVMVPA
Mb2148c|M.bovis_AF2122/97           ----------GRIVLATVKGDVHDIGKNLVDIVLSNNGYEVVNIGIKQPI
Rv2124c|M.tuberculosis_H37Rv        ----------GRIVLATVKGDVHDIGKNLVDIILSNNGYEVVNIGIKQPI
MLBr_01307|M.leprae_Br4923          GL------AKGRIVLATVKGDVHDIGKNLVDIILSNNGYEVVNLGIKQPI
TH_0958|M.thermoresistible__bu      ----------GRIVLATVKGDVHDIGKNLVDIILTNNGYEVVNLGIKQPI
                                              * *::*************:*.::*  *.: *:::*:  * 

MAV_2379|M.avium_104                QKILDAAKEHDADIIGLSGLITPSLDEMSNFAAEMERE--GLQIPLLIGG
Mvan_3474|M.vanbaalenii_PYR-1       QKILDAAKEHNADIIGLSGLITPSLDEMANFAVEMERE--GLEIPLLIGG
MAB_2129|M.abscessus_ATCC_1997      QKILDAAKEHDADIIGLSGLITPSLDEMANFAVEMERE--GLEIPLLIGG
Mflv_3053|M.gilvum_PYR-GCK          QKILDAAREHDADIIGLSGLITPSLDEMSNFAVEMERA--GLEIPLLIGG
MMAR_4825|M.marinum_M               EKILAAAREYDADIIGLSGLITPSLDEMVNFAAAMERE--GMQIPLLIGG
MUL_0395|M.ulcerans_Agy99           EKILAAAREYDADIIGLSGLITPSLDEMVNFAAAMERE--GMQIPLLIGG
MSMEG_4185|M.smegmatis_MC2_155      QKILDAAKEHNADIIGLSGLITPSLDEMVNFAAEMERE--GMDIPLLIGG
Mb2148c|M.bovis_AF2122/97           ATILEVAEDKSADVVGMSGLLVKSTVVMKENLEEMNTRGVAEKFPVLLGG
Rv2124c|M.tuberculosis_H37Rv        ATILEVAEDKSADVVGMSGLLVKSTVVMKENLEEMNTRGVAEKFPVLLGG
MLBr_01307|M.leprae_Br4923          TNILEVAEDKSADVVGMSGLLVKSTVIMKENLEEMNTRGVAEKFPVLLGG
TH_0958|M.thermoresistible__bu      STILEVAEDKNADVVGMSGLLVKSTVVMKENLEEMNARGVAERFPVLLGG
                                     .** .*.: .**::*:***:. *   * :    *:    .  :*:*:**

MAV_2379|M.avium_104                ATTSRAHTAVKISPRRSGPVVWVKDASRSVPVAAALLDDKQRPALLEATE
Mvan_3474|M.vanbaalenii_PYR-1       ATTSRAHTAVKIAPRRGGPVVWVKDASRSVPVAAALLDDRQRPALLEATE
MAB_2129|M.abscessus_ATCC_1997      ATTSRAHTAVKISPRRKGPVVWVKDASRSVPVAAALLDDKQRPGLLEATE
Mflv_3053|M.gilvum_PYR-GCK          ATTSRAHTAVKISPRRSGPVVWVKDASRSVPVAAALLDDKQRPALLEATE
MMAR_4825|M.marinum_M               ATTSRAHTAVKVAPRRSGPVVWVKDASRSVPVAAALLDDKQRPGLLEATA
MUL_0395|M.ulcerans_Agy99           ATTSRAHTAVKVAPRRSGPVVWVKDASRSVPVAAALLDDKQRPGLLEATA
MSMEG_4185|M.smegmatis_MC2_155      ATTSRAHTAVKVAPRRSGPVVWVKDASRSVPVAAALLDDKQRPALLEATE
Mb2148c|M.bovis_AF2122/97           AALTRSYVENDLAEIYQGEVHYARDAFEGLKLMDTIMSAKRGEAPDENSP
Rv2124c|M.tuberculosis_H37Rv        AALTRSYVENDLAEIYQGEVHYARDAFEGLKLMDTIMSAKRGEAPDENSP
MLBr_01307|M.leprae_Br4923          AALTRSYVENDLAEVYEGEVHYARDAFEGLKLMDTIMSAKRGEALAPGSP
TH_0958|M.thermoresistible__bu      AALTRGYVEDDLSEIYEGEVYYARDAFEGLRLMDRIMSEKRGGGPDPDSP
                                    *: :*.:.  .::    * * :.:** ..: :   ::. ::  .    : 

MAV_2379|M.avium_104                KDYASLR-----ERHAQKNERPMVTLEKARANRTPIDWDGYTPPVPAIGA
Mvan_3474|M.vanbaalenii_PYR-1       ADYASLR-----ERHAQKNERPMLTLEKARANRTPVEWDGYTPPVPAQGL
MAB_2129|M.abscessus_ATCC_1997      KDYASLR-----ERHAQKNERPTLTLEKARANRTPVEWDGYTPPVPAQGL
Mflv_3053|M.gilvum_PYR-GCK          KDYASLR-----ERHAQKNDRPMLTLEKARANRTPIEWDGYTPPVPAQGV
MMAR_4825|M.marinum_M               ADYAALR-----ERHSQKNERPMLTLEKARANRTPIDWDGYTPPLPAQGL
MUL_0395|M.ulcerans_Agy99           ADYAALR-----ERHSQKNERPMLTLEKARANRTPIDWDGYTPPLPAQGL
MSMEG_4185|M.smegmatis_MC2_155      KDYASLR-----ERHAQKNERPMVTLEKARANRTPIDWDGYTPPVPAQGL
Mb2148c|M.bovis_AF2122/97           EAIKARE---KEAERKARHQRSKRIAAQRKAAEEPVEVPERSDVAADIEV
Rv2124c|M.tuberculosis_H37Rv        EAIKARE---KEAERKARHQRSKRIAAQRKAAEEPVEVPERSDVAADIEV
MLBr_01307|M.leprae_Br4923          ESLAAEADRNKETERKARHERSKRIAVQRKAAEEPVEVPERSDVPSDVEV
TH_0958|M.thermoresistible__bu      EAIAARE---KEAERKARRARSKRIAAERKAKEEPVEVPARSDVAADVEV
                                        :        .:  :. *.     : :* . *::    :   .    

MAV_2379|M.avium_104                GIREFQDYDLAELREYIDWQPFFNAWEMKGRFPDILNNPATGEAARKLYD
Mvan_3474|M.vanbaalenii_PYR-1       GVREFKDYDLAELREYIDWQPFFNAWEMKGRFPDILNNPATGEAARKLYD
MAB_2129|M.abscessus_ATCC_1997      GVREFLDYDLAEVREYIDWQPFFNAWEMKGRFPDILNNPATGEAARKLHD
Mflv_3053|M.gilvum_PYR-GCK          GVREFIDYDLAELREYIDWQPFFNAWEMKGRFPDILNNPATGEAARKLYN
MMAR_4825|M.marinum_M               GVREFHDYDLAELREYIDWQPFFNAWEMKGRFPDILNNPATGEAARKLYN
MUL_0395|M.ulcerans_Agy99           GVREFHDYDLAELREYIDWQPFFNAWEMKGRFPDILNNPATGEAARKLYN
MSMEG_4185|M.smegmatis_MC2_155      GIREFENYDLSELRQYIDWQPFFNAWEMKGKFPDILNNPASGEAARKLYE
Mb2148c|M.bovis_AF2122/97           PAPPFWGSRIVKGLAVADYTGLLDERALFLGQWGLRGQRGGEGPSYEDLV
Rv2124c|M.tuberculosis_H37Rv        PAPPFWGSRIVKGLAVADYTGLLDERALFLGQWGLRGQRGGEGPSYEDLV
MLBr_01307|M.leprae_Br4923          PAPPFWGSRIIKGLAVADYTGFLDERALFLGQWGLRGVRGGAGPSYEDLV
TH_0958|M.thermoresistible__bu      PVPPFWGTRIVKGVAVADYAGTLDERALFLGQWGLRGARGGDGPSYEELV
                                        * .  : :     *:   ::   :     .: .  .   .: :   

MAV_2379|M.avium_104                DAQEMLDTLIKEKWLTAN-------AVIGFFPANAIGPGFEDIELYTDDT
Mvan_3474|M.vanbaalenii_PYR-1       DAQEMLDTLIKEKWLTAN-------GVIGFFPANAS-PGGDDIVVYTDDT
MAB_2129|M.abscessus_ATCC_1997      DAQQILDTLIKEKWLTAN-------GVIGFFPANAVGPGFEDIEVYTDDT
Mflv_3053|M.gilvum_PYR-GCK          DAQEMLDTLIKEKWLTAN-------GVIGFFCANAV---GDDIEVYTDDT
MMAR_4825|M.marinum_M               DAQEMLDTLIREKWLTAN-------GVIGFFPANAVG---DDIEVYTDET
MUL_0395|M.ulcerans_Agy99           DAQEMLDTLIREKWLTAN-------GVIGFFPANAVG---DDIEVYTDET
MSMEG_4185|M.smegmatis_MC2_155      EAQEMLDTLIKEKWLTAN-------GVIGFFPANAVG---DDIEVYTDDT
Mb2148c|M.bovis_AF2122/97           ETEGRPRLRYWLDRLSTDGILAHAAVVYGYFPAVSEG---NDIVVLTEPK
Rv2124c|M.tuberculosis_H37Rv        ETEGRPRLRYWLDRLSTDGILAHAAVVYGYFPAVSEG---NDIVVLTEPK
MLBr_01307|M.leprae_Br4923          QTEGRPRLRYWLDRLSTYGVLAYAAVVYGYFPAVSED---NDIVVLAEPR
TH_0958|M.thermoresistible__bu      ETEGRPRLRYWLDRLATEGILAHAAVVYGYFPAVSQG---DDVIVLTEPE
                                    :::         . *::         * *:* * :     :*: : ::  

MAV_2379|M.avium_104                RTEVLTTLHNLRQQGEHRDGIPNRSLGDYVAPKETGHRDYIGAFAVTAGL
Mvan_3474|M.vanbaalenii_PYR-1       RTEVLTTLHNLRQQGEHRSGIPNRSLGDFIAPKESGLRDYIGAFAVTAGL
MAB_2129|M.abscessus_ATCC_1997      RTEVLTTLHNLRQQGEHRDGIPNRSLGDYIAPKETGLRDYIGAFAVTAGL
Mflv_3053|M.gilvum_PYR-GCK          RTEVLTTLYNLRQQGEHRDGIPNRSQGDFIAPKETGLRDYIGAFAVTAGL
MMAR_4825|M.marinum_M               RAEVLTTLHNLRQQGEHRAGIPNRSLGDFIAPKDTGLADYVGAFAVTAGL
MUL_0395|M.ulcerans_Agy99           RAEVLTTLHNLRQQGEHRAGIPNRSLGDFIAPKDTGLADYVGAFAVTAGL
MSMEG_4185|M.smegmatis_MC2_155      RTEVLTTLRNLRQQGEHRDGIPNRSLGDFIAPKETGLADYIGAFAVTAGL
Mb2148c|M.bovis_AF2122/97           PDAPVRYRFHFPRQQRGRFLCIADFIRSRELAAERGEVDVLPFQLVTMGQ
Rv2124c|M.tuberculosis_H37Rv        PDAPVRYRFHFPRQQRGRFLCIADFIRSRELAAERGEVDVLPFQLVTMGQ
MLBr_01307|M.leprae_Br4923          PDAEQRYRFTFPRQQRGRFLCIADFIRSRDLATERSEVDVLPFQLVTMGQ
TH_0958|M.thermoresistible__bu      PDADERFRFTFPRQQRGRFLCIADFIRSRELAAKTGQVDVLPFQLVTMGQ
                                              : :* . *         .   . . .  * :    ** * 

MAV_2379|M.avium_104                GSQEKIAEFKAALDDYSAILLESIADRLAEAFAERMHQRVRKEFWGYQPD
Mvan_3474|M.vanbaalenii_PYR-1       GSQDKIMEFKAALDDYSAILLESLADRLAEAFAERMHERVRKEFWGYQPD
MAB_2129|M.abscessus_ATCC_1997      GSQDKIMEFKADLDDYSAILLESIADRLAEAFAERMHQRVRTEFWGFQPD
Mflv_3053|M.gilvum_PYR-GCK          GSQAKIMEFKAALDDYSAILLESLADRLAEAFAERMHERVRTEFWGYQPD
MMAR_4825|M.marinum_M               GSQTKIVEFKEALDDYSAILLESIADRLAEAFAERMHQRVREEFWGYQPD
MUL_0395|M.ulcerans_Agy99           GSQTKIVEFKEALDDYSAILLESIADRLAEAFAERMHQRVREEFWGYQPD
MSMEG_4185|M.smegmatis_MC2_155      GSAEKIAEFKADHDDYSAILLESLADRLAEAFAERMHQRVRTELWAYQPD
Mb2148c|M.bovis_AF2122/97           PIADFANELFASNAYRDYLEVHGIGVQLTEALAEYWHRRIREELKFSGDR
Rv2124c|M.tuberculosis_H37Rv        PIADFANELFASNAYRDYLEVHGIGVQLTEALAEYWHRRIREELKFSGDR
MLBr_01307|M.leprae_Br4923          PIADFVGELFVSNSYRDYLEVHGIGVQLTEALAEYWHRRIREELKFSGNR
TH_0958|M.thermoresistible__bu      PIADFANELFASNAYRDYLEVHGIGVQLTEAFAEYWHRRIREELRFG-DR
                                           *:       . : :..:. :*:**:**  *.*:* *:      

MAV_2379|M.avium_104                EQLDN-----DALIDEKYRGIRPAPGYPACPEHTEKVTLWKLMDVKERTG
Mvan_3474|M.vanbaalenii_PYR-1       EQLDN-----DALIGEKYVGIRPAPGYPACPEHTEKATLWKLMDVKERTG
MAB_2129|M.abscessus_ATCC_1997      EQLDN-----EALIGEKYRGIRPAPGYPACPEHTEKVTLFDLLDVTKRTG
Mflv_3053|M.gilvum_PYR-GCK          EQLDN-----NALIAERYVGIRPAPGYPSCPEHTEKATLFGLLDATERTG
MMAR_4825|M.marinum_M               EQLDN-----EALIGERYVGIRPAPGYPACPEHTEKTTLFELMDVTKRTG
MUL_0395|M.ulcerans_Agy99           EQLDN-----EALIGERYVGIRPAPGYPACPEHTEKTTLFELMDVTKRTG
MSMEG_4185|M.smegmatis_MC2_155      EELDN-----EALIAERYRGIRPAPGYPACPEHTEKATLFKLLDVTERTG
Mb2148c|M.bovis_AF2122/97           AMAAEDPEAKEDYFKLGYRGARFAFGYGACPDLEDRAKMMALLEP-ERIG
Rv2124c|M.tuberculosis_H37Rv        AMAAEDPEAKEDYFKLGYRGARFAFGYGACPDLEDRAKMMALLEP-ERIG
MLBr_01307|M.leprae_Br4923          TMSADDPEAVEDYFKLGYRGARFAFGYGACPDLEDRIKMMELLQP-ERIG
TH_0958|M.thermoresistible__bu      AMAAEDPESVEEYFKLGYRGARFSFGYGACPDLEDRKKMMELLEP-ERIG
                                        :     :  :   * * * : ** :**:  :: .:  *::  :* *

MAV_2379|M.avium_104                IELTESMAMWPGAAVSGWYFSHPQSQYFVVGRLAQDQVADYAKRKGWTLA
Mvan_3474|M.vanbaalenii_PYR-1       IELTESMAMWPGAAVSGWYFSHPQSQYFVVGRLAQDQVADYAKRKGWTLA
MAB_2129|M.abscessus_ATCC_1997      IELTESMAMWPGAAVSGWYFAHPQSQYFVVGRLAQDQVADYAKRKGWTLQ
Mflv_3053|M.gilvum_PYR-GCK          IELTESMAMWPGAAVSGWYFSHPQSQYFVVGRLAQDQVADYARRKGWTLQ
MMAR_4825|M.marinum_M               IELTESMAMWPGAAVSGWYFSHPQSQYFVVGRMAQDQVADYAKRKGWTLP
MUL_0395|M.ulcerans_Agy99           IELTESMAMWPGAAVSGWYFSHPQSQYFVVGRMAQDQVADYAKRKGWTLP
MSMEG_4185|M.smegmatis_MC2_155      IELTESMAMWPGAAVSGWYFSHPQSQYFVVGRLAQDQVADYARRKGWTLQ
Mb2148c|M.bovis_AF2122/97           VTLSEELQLHPEQSTDAFVLHHPEAKYFNV--------------------
Rv2124c|M.tuberculosis_H37Rv        VTLSEELQLHPEQSTDAFVLHHPEAKYFNV--------------------
MLBr_01307|M.leprae_Br4923          VTISEELQLHPEQSTDAFVLHHPAAKYFNV--------------------
TH_0958|M.thermoresistible__bu      VVLSEELQLHPEQSTDAFVLHHPEAKYFNV--------------------
                                    : ::*.: : *  :...: : ** ::** *                    

MAV_2379|M.avium_104                EAERWLAPNLGYNPED
Mvan_3474|M.vanbaalenii_PYR-1       EAERWLAPNLGYNPED
MAB_2129|M.abscessus_ATCC_1997      EAERWLGPNLGYNPED
Mflv_3053|M.gilvum_PYR-GCK          EAERWLAPNLGYNPED
MMAR_4825|M.marinum_M               EAERWLGPNLGYNPED
MUL_0395|M.ulcerans_Agy99           EAERWLGPNLGYNPED
MSMEG_4185|M.smegmatis_MC2_155      EAERWLAPNLGYNPED
Mb2148c|M.bovis_AF2122/97           ----------------
Rv2124c|M.tuberculosis_H37Rv        ----------------
MLBr_01307|M.leprae_Br4923          ----------------
TH_0958|M.thermoresistible__bu      ----------------