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RAYDPDLVVIFSPDHYNGFFYRAMHPFCIGMYASAVGDYGTHIGALDVPTDLAADCAKAVLGADVDVAVS ASMDVDHGTVQPLEKLFGTATARPVIPIFINAIAAPLGPLRRCRALGTAVGTFLSTLDLRVLVIGSGGLS HSPPVPTLHSADPQVRERIVHGQPLTPAQRQARQTVVMEAAKSFAAGNSDLQPLNPAWDQRFLEIIDNGH LSDLDRWSNSFVTHEGGSLAHEIRTWISAFAAMAVAGPYQTKVRYYKQAADLIAGFAIRTAVPIP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_0347 | mhpB | - | 100% (276) | 3-(2,3-dihydroxyphenyl)propionate dioxygenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_2402 | mhpB | 1e-107 | 66.67% (273) | 3-(2,3-dihydroxyphenyl)propionate dioxygenase |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4372 | mhpB | 2e-76 | 47.99% (273) | 3-(2,3-dihydroxyphenyl)propionate dioxygenase |
| M. marinum M | MMAR_4776 | mhpB | 1e-158 | 98.91% (276) | extradiol dioxygenase, MhpB |
| M. avium 104 | MAV_1947 | mhpB | 2e-32 | 33.33% (273) | 3-(2,3-dihydroxyphenyl)propionate dioxygenase |
| M. smegmatis MC2 155 | MSMEG_4865 | mhpB | 1e-104 | 64.96% (274) | 3-(2,3-dihydroxyphenyl)propionate dioxygenase |
| M. thermoresistible (build 8) | TH_0969 | - | 1e-105 | 66.06% (274) | metapyrocatechase 1 |
| M. vanbaalenii PYR-1 | Mvan_4244 | mhpB | 1e-108 | 66.30% (273) | 3-(2,3-dihydroxyphenyl)propionate dioxygenase |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_0347|M.ulcerans_Agy99 ----------------------------------------MRAYDPDLVV
MMAR_4776|M.marinum_M ----------MSHSPLLNLPGPRLDLLDEVHAAIAEAAEFVRAYDPDLVV
MSMEG_4865|M.smegmatis_MC2_155 ----------MSHSPLLNLPGPSAELLDQITDAIADARKFVEQFDPELVV
TH_0969|M.thermoresistible__bu ----------MSHSPLLNLPGPPPEVLDDIAAALGRARDFVTAYDPELVV
Mflv_2402|M.gilvum_PYR-GCK MAKSQIALCCMSHSPLLNLPGPAQELLDEIDKAIAAARDFVAEFDPELVV
Mvan_4244|M.vanbaalenii_PYR-1 ----------MSHSPLLNLPGPAQELLDDIEGAIAAAREFVAAFDPDLVV
MAB_4372|M.abscessus_ATCC_1997 -MLMTCALVGLSHSPLVGKNDPASDTLARINSAIEHARSFVHEFRPELVV
MAV_1947|M.avium_104 -MTTHRLVVCASHSPGKER-DVAQAFGLEFRSALAQAADQVRAFDPELVI
: : *:**:
MUL_0347|M.ulcerans_Agy99 IFSPDHYNGFFYRAMHPFCIGMYASAVGDYGTHIGALDVPTDLAADCAKA
MMAR_4776|M.marinum_M IFSPDHYNGFFYRAMPPFCIGMYASAVGDYGTHIGALDVPTDLAADCAKA
MSMEG_4865|M.smegmatis_MC2_155 TFSPDHYNGFFYRLMPPFCIGTAAAGVGDYGTYQGPLPVDADIANACAES
TH_0969|M.thermoresistible__bu IFAPDHYNGFFYRLMPPFCISTAASGVGDYGSHAGPLDVPADLASRCAEA
Mflv_2402|M.gilvum_PYR-GCK TFSPDHYNGFFYRAMPPFCIGTAAEGVGDYGTHEGPLDVPSDLATDCARA
Mvan_4244|M.vanbaalenii_PYR-1 TFSPDHYNGFFYRAMPPFCVGTAAAGVGDYGTYQGPLDVPADLAIDCARA
MAB_4372|M.abscessus_ATCC_1997 LYAPDHYNGFFYKEMPPFCLATEAHAVGDFGSPAGQLSVDSDAAQLLARG
MAV_1947|M.avium_104 VFGGDHRR-AFTTVVPTFGVALSASIIAEGAHPAGAMSVPSAWARALCEH
:. ** . * : .* :. * :.: . * : * : * ..
MUL_0347|M.ulcerans_Agy99 VLGADVDVAVSASMDVDHGTVQPLEKLFGTATARPVIPIFINAIAAPLGP
MMAR_4776|M.marinum_M VLGADVDVAVSASMDVDHGTVQPLEKLFGTATARPVIPIFINAIAAPLGP
MSMEG_4865|M.smegmatis_MC2_155 LWESGVDIAISTAMDVDHGTVQPLQELFGDATARPVVPIFINSVATPLGP
TH_0969|M.thermoresistible__bu VLDAGVDVAISAGIEVDHGTVQPLQILFGDAAARPVIPIFINSVATPLGP
Mflv_2402|M.gilvum_PYR-GCK VLDHDVDVALSAAMDVDHGTVQPLQKLFGDATAKPVIPVFINSVATPLGP
Mvan_4244|M.vanbaalenii_PYR-1 VLDSDVDVAVSAAMDVDHGTVQPLQKLFGDATAKPVIPVFVNSVATPLGP
MAB_4372|M.abscessus_ATCC_1997 VLSRNVDLTVSARMTVDHGFTQPLEMLFGGIDRVPMVPIFINGVAGPFGP
MAV_1947|M.avium_104 LLAEEFDLAVCRDVALDHAFAQPIRDLVGELDAKPVIPVAVNCATAPLPT
: .*:::. : :**. .**:. *.* *::*: :* : *: .
MUL_0347|M.ulcerans_Agy99 LRRCRALGTAVGTFLSTLDLRVLVIGSGGLSHSPPVPTLHSADPQVRERI
MMAR_4776|M.marinum_M LRRCRALGTAVGTFLSTLDMRVLVIGSGGLSHSPPVPTLHSADPQVRERI
MSMEG_4865|M.smegmatis_MC2_155 LSRSRALGAAVGTFLATLDKRVLIVGSGGLSHDPPVPTLATAPPAALDRI
TH_0969|M.thermoresistible__bu LHRSRALGRAVGEFLAGLDERVLVIGSGGLSHDPPVPTLATAPPAALERI
Mflv_2402|M.gilvum_PYR-GCK IRRVRALGAAVGAHLATLGKRVLVIGSGGLSHDPPVPTLATAPPAALDRI
Mvan_4244|M.vanbaalenii_PYR-1 MRRVRALGAAVGTHLAGLGKRVLVIGSGGLSHDPPVPTLATAPPAALDRI
MAB_4372|M.abscessus_ATCC_1997 LNRIRALGTALGHEAAALGRRVLFLASGGLSHDPPVPVLQGAPPRVADAL
MAV_1947|M.avium_104 GRRVAGFGAAVGRFLDSVDQRVLLIGTGGLSHSPPS------------LE
* .:* *:* :. ***.:.:*****.**
MUL_0347|M.ulcerans_Agy99 VHGQPLTPAQRQARQTVVMEAAKSFAAGNSDLQPLNPAWDQRFLEIIDNG
MMAR_4776|M.marinum_M VHGQPLTPAQRQARQTVVMEAAKSFAAGNSDLQPLNPAWDQRFLEIIDNG
MSMEG_4865|M.smegmatis_MC2_155 VHGAPMTPEQRMARQEAVIKAAHDFAHGQSPLRSLNPDWDRSLLEIFDEG
TH_0969|M.thermoresistible__bu VEGRPMTPEQRMARQSAVIAAAESFARGEGGLQPLNPDWDRRLLDIFDQN
Mflv_2402|M.gilvum_PYR-GCK VRGVPMTTDQRQARQTAVIEAAREFASGRGTLAPLNPDWDRAFLDIVDSG
Mvan_4244|M.vanbaalenii_PYR-1 VRGVPMTTEQRQARQAAVIEAAREFASGQGALAPLNPDWDRAFLDLLDNG
MAB_4372|M.abscessus_ATCC_1997 IEGHPPSPEQRARGEERVLAAGREYAAGSSSRIPINPIWDNEVLDTFESG
MAV_1947|M.avium_104 VDAYKLSDDERARIIADGMADARN---------KIRPDWDAEVLEAMSIW
: . : :* : ... :.* ** .*: ..
MUL_0347|M.ulcerans_Agy99 HLSDLDRWSNSFVTHEGGSLAHEIRTWISAFAAMAVAGPYQTKVRYYKQA
MMAR_4776|M.marinum_M HLSDLDRWSNSFVTHEGGSSAHEIRTWISAFAAMAVAGPYQTKVRYYKQA
MSMEG_4865|M.smegmatis_MC2_155 RLSDLDGWTNTFITGEGGNSAHEIRTWVAAFAALAAHGEYQTGNHFYRAA
TH_0969|M.thermoresistible__bu RLAELDGWTNESITAEAGNSAHEIRTWVAAFSALATQGDYRTGHHFYRAA
Mflv_2402|M.gilvum_PYR-GCK RLAEVDGWDNGWIAEQAGNSAHEVRTWIAAFAALAAQGEYVTENRFYRAA
Mvan_4244|M.vanbaalenii_PYR-1 RLAEVDSWDNRWIAEQAGNSAHEVRTWVAAFAALAAQGKYETGNRYYRAA
MAB_4372|M.abscessus_ATCC_1997 DLEAIDSWTPEWMGSEGGGSAHEVRTWVAAYSSLAASGPYQMLTRFYAAV
MAV_1947|M.avium_104 DAEALIRLVDSAHTR-AGAGANEIRTWVAAG---AAGGGRPVAALAYEPV
: .* *:*:***::* *. * * .
MUL_0347|M.ulcerans_Agy99 ADLIAGFAIRTAVPIP---------
MMAR_4776|M.marinum_M ADLIAGFAIRTAVPIP---------
MSMEG_4865|M.smegmatis_MC2_155 PELIAGFAIRTAVPST---------
TH_0969|M.thermoresistible__bu PELIAGFAVRTAVPDDTRERTGVPS
Mflv_2402|M.gilvum_PYR-GCK PELIAGFAIRTAVTT----------
Mvan_4244|M.vanbaalenii_PYR-1 PELIAGFAIRTAVCTS---------
MAB_4372|M.abscessus_ATCC_1997 PEWIAGFAVSTAMRQVGP-------
MAV_1947|M.avium_104 PEWITGMAVATSAAGASWQDRRTRV
.: *:*:*: *: