For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
SHSPLLNLPGPSAELLDQITDAIADARKFVEQFDPELVVTFSPDHYNGFFYRLMPPFCIGTAAAGVGDYG TYQGPLPVDADIANACAESLWESGVDIAISTAMDVDHGTVQPLQELFGDATARPVVPIFINSVATPLGPL SRSRALGAAVGTFLATLDKRVLIVGSGGLSHDPPVPTLATAPPAALDRIVHGAPMTPEQRMARQEAVIKA AHDFAHGQSPLRSLNPDWDRSLLEIFDEGRLSDLDGWTNTFITGEGGNSAHEIRTWVAAFAALAAHGEYQ TGNHFYRAAPELIAGFAIRTAVPST*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4865 | mhpB | - | 100% (306) | 3-(2,3-dihydroxyphenyl)propionate dioxygenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_2402 | mhpB | 1e-133 | 74.59% (303) | 3-(2,3-dihydroxyphenyl)propionate dioxygenase |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4372 | mhpB | 3e-88 | 51.49% (303) | 3-(2,3-dihydroxyphenyl)propionate dioxygenase |
| M. marinum M | MMAR_4776 | mhpB | 1e-118 | 65.79% (304) | extradiol dioxygenase, MhpB |
| M. avium 104 | MAV_1947 | mhpB | 9e-33 | 33.33% (288) | 3-(2,3-dihydroxyphenyl)propionate dioxygenase |
| M. thermoresistible (build 8) | TH_0969 | - | 1e-136 | 75.33% (304) | metapyrocatechase 1 |
| M. ulcerans Agy99 | MUL_0347 | mhpB | 1e-104 | 64.96% (274) | 3-(2,3-dihydroxyphenyl)propionate dioxygenase |
| M. vanbaalenii PYR-1 | Mvan_4244 | mhpB | 1e-135 | 75.25% (303) | 3-(2,3-dihydroxyphenyl)propionate dioxygenase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2402|M.gilvum_PYR-GCK MAKSQIALCCMSHSPLLNLPGPAQELLDEIDKAIAAARDFVAEFDPELVV
Mvan_4244|M.vanbaalenii_PYR-1 ----------MSHSPLLNLPGPAQELLDDIEGAIAAAREFVAAFDPDLVV
MSMEG_4865|M.smegmatis_MC2_155 ----------MSHSPLLNLPGPSAELLDQITDAIADARKFVEQFDPELVV
TH_0969|M.thermoresistible__bu ----------MSHSPLLNLPGPPPEVLDDIAAALGRARDFVTAYDPELVV
MMAR_4776|M.marinum_M ----------MSHSPLLNLPGPRLDLLDEVHAAIAEAAEFVRAYDPDLVV
MUL_0347|M.ulcerans_Agy99 ----------------------------------------MRAYDPDLVV
MAB_4372|M.abscessus_ATCC_1997 -MLMTCALVGLSHSPLVGKNDPASDTLARINSAIEHARSFVHEFRPELVV
MAV_1947|M.avium_104 -MTTHRLVVCASHSPGKER-DVAQAFGLEFRSALAQAADQVRAFDPELVI
: : *:**:
Mflv_2402|M.gilvum_PYR-GCK TFSPDHYNGFFYRAMPPFCIGTAAEGVGDYGTHEGPLDVPSDLATDCARA
Mvan_4244|M.vanbaalenii_PYR-1 TFSPDHYNGFFYRAMPPFCVGTAAAGVGDYGTYQGPLDVPADLAIDCARA
MSMEG_4865|M.smegmatis_MC2_155 TFSPDHYNGFFYRLMPPFCIGTAAAGVGDYGTYQGPLPVDADIANACAES
TH_0969|M.thermoresistible__bu IFAPDHYNGFFYRLMPPFCISTAASGVGDYGSHAGPLDVPADLASRCAEA
MMAR_4776|M.marinum_M IFSPDHYNGFFYRAMPPFCIGMYASAVGDYGTHIGALDVPTDLAADCAKA
MUL_0347|M.ulcerans_Agy99 IFSPDHYNGFFYRAMHPFCIGMYASAVGDYGTHIGALDVPTDLAADCAKA
MAB_4372|M.abscessus_ATCC_1997 LYAPDHYNGFFYKEMPPFCLATEAHAVGDFGSPAGQLSVDSDAAQLLARG
MAV_1947|M.avium_104 VFGGDHRR-AFTTVVPTFGVALSASIIAEGAHPAGAMSVPSAWARALCEH
:. ** . * : .* :. * :.: . * : * : * ..
Mflv_2402|M.gilvum_PYR-GCK VLDHDVDVALSAAMDVDHGTVQPLQKLFGDATAKPVIPVFINSVATPLGP
Mvan_4244|M.vanbaalenii_PYR-1 VLDSDVDVAVSAAMDVDHGTVQPLQKLFGDATAKPVIPVFVNSVATPLGP
MSMEG_4865|M.smegmatis_MC2_155 LWESGVDIAISTAMDVDHGTVQPLQELFGDATARPVVPIFINSVATPLGP
TH_0969|M.thermoresistible__bu VLDAGVDVAISAGIEVDHGTVQPLQILFGDAAARPVIPIFINSVATPLGP
MMAR_4776|M.marinum_M VLGADVDVAVSASMDVDHGTVQPLEKLFGTATARPVIPIFINAIAAPLGP
MUL_0347|M.ulcerans_Agy99 VLGADVDVAVSASMDVDHGTVQPLEKLFGTATARPVIPIFINAIAAPLGP
MAB_4372|M.abscessus_ATCC_1997 VLSRNVDLTVSARMTVDHGFTQPLEMLFGGIDRVPMVPIFINGVAGPFGP
MAV_1947|M.avium_104 LLAEEFDLAVCRDVALDHAFAQPIRDLVGELDAKPVIPVAVNCATAPLPT
: .*:::. : :**. .**:. *.* *::*: :* : *: .
Mflv_2402|M.gilvum_PYR-GCK IRRVRALGAAVGAHLATLGKRVLVIGSGGLSHDPPVPTLATAPPAALDRI
Mvan_4244|M.vanbaalenii_PYR-1 MRRVRALGAAVGTHLAGLGKRVLVIGSGGLSHDPPVPTLATAPPAALDRI
MSMEG_4865|M.smegmatis_MC2_155 LSRSRALGAAVGTFLATLDKRVLIVGSGGLSHDPPVPTLATAPPAALDRI
TH_0969|M.thermoresistible__bu LHRSRALGRAVGEFLAGLDERVLVIGSGGLSHDPPVPTLATAPPAALERI
MMAR_4776|M.marinum_M LRRCRALGTAVGTFLSTLDMRVLVIGSGGLSHSPPVPTLHSADPQVRERI
MUL_0347|M.ulcerans_Agy99 LRRCRALGTAVGTFLSTLDLRVLVIGSGGLSHSPPVPTLHSADPQVRERI
MAB_4372|M.abscessus_ATCC_1997 LNRIRALGTALGHEAAALGRRVLFLASGGLSHDPPVPVLQGAPPRVADAL
MAV_1947|M.avium_104 GRRVAGFGAAVGRFLDSVDQRVLLIGTGGLSHSPPS------------LE
* .:* *:* :. ***.:.:*****.**
Mflv_2402|M.gilvum_PYR-GCK VRGVPMTTDQRQARQTAVIEAAREFASGRGTLAPLNPDWDRAFLDIVDSG
Mvan_4244|M.vanbaalenii_PYR-1 VRGVPMTTEQRQARQAAVIEAAREFASGQGALAPLNPDWDRAFLDLLDNG
MSMEG_4865|M.smegmatis_MC2_155 VHGAPMTPEQRMARQEAVIKAAHDFAHGQSPLRSLNPDWDRSLLEIFDEG
TH_0969|M.thermoresistible__bu VEGRPMTPEQRMARQSAVIAAAESFARGEGGLQPLNPDWDRRLLDIFDQN
MMAR_4776|M.marinum_M VHGQPLTPAQRQARQTVVMEAAKSFAAGNSDLQPLNPAWDQRFLEIIDNG
MUL_0347|M.ulcerans_Agy99 VHGQPLTPAQRQARQTVVMEAAKSFAAGNSDLQPLNPAWDQRFLEIIDNG
MAB_4372|M.abscessus_ATCC_1997 IEGHPPSPEQRARGEERVLAAGREYAAGSSSRIPINPIWDNEVLDTFESG
MAV_1947|M.avium_104 VDAYKLSDDERARIIADGMADARN---------KIRPDWDAEVLEAMSIW
: . : :* : ... :.* ** .*: ..
Mflv_2402|M.gilvum_PYR-GCK RLAEVDGWDNGWIAEQAGNSAHEVRTWIAAFAALAAQGEYVTENRFYRAA
Mvan_4244|M.vanbaalenii_PYR-1 RLAEVDSWDNRWIAEQAGNSAHEVRTWVAAFAALAAQGKYETGNRYYRAA
MSMEG_4865|M.smegmatis_MC2_155 RLSDLDGWTNTFITGEGGNSAHEIRTWVAAFAALAAHGEYQTGNHFYRAA
TH_0969|M.thermoresistible__bu RLAELDGWTNESITAEAGNSAHEIRTWVAAFSALATQGDYRTGHHFYRAA
MMAR_4776|M.marinum_M HLSDLDRWSNSFVTHEGGSSAHEIRTWISAFAAMAVAGPYQTKVRYYKQA
MUL_0347|M.ulcerans_Agy99 HLSDLDRWSNSFVTHEGGSLAHEIRTWISAFAAMAVAGPYQTKVRYYKQA
MAB_4372|M.abscessus_ATCC_1997 DLEAIDSWTPEWMGSEGGGSAHEVRTWVAAYSSLAASGPYQMLTRFYAAV
MAV_1947|M.avium_104 DAEALIRLVDSAHTR-AGAGANEIRTWVAAG---AAGGGRPVAALAYEPV
: .* *:*:***::* *. * * .
Mflv_2402|M.gilvum_PYR-GCK PELIAGFAIRTAVTT----------
Mvan_4244|M.vanbaalenii_PYR-1 PELIAGFAIRTAVCTS---------
MSMEG_4865|M.smegmatis_MC2_155 PELIAGFAIRTAVPST---------
TH_0969|M.thermoresistible__bu PELIAGFAVRTAVPDDTRERTGVPS
MMAR_4776|M.marinum_M ADLIAGFAIRTAVPIP---------
MUL_0347|M.ulcerans_Agy99 ADLIAGFAIRTAVPIP---------
MAB_4372|M.abscessus_ATCC_1997 PEWIAGFAVSTAMRQVGP-------
MAV_1947|M.avium_104 PEWITGMAVATSAAGASWQDRRTRV
.: *:*:*: *: