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TPADSSAGFSGTNTLAQATSPYLRQHADNPVHWQQWTPQALADAAARDVPILLSIGYAACHWCHVMAHES FEDDEVAAVMNAGFVNIKVDREERPDIDAVYMNATVALTGQGGWPMTCFLTPDGRPFYCGTYYPKAGFLQ LLSAVSETWRERRGEVEEASDHIAGELRSMASGPPGGGPDVAPELCDHAVAVVLGEQDTVHGGWGTAPKF PPSALLEALLRHYERTGSLAALAAVSRTGAAMARGGIYDQLAGGFARYSVDKAWVVPHFEKMLYDNALLL RAYAHWARRTGDELACRVAAQTAGFLLDGLAAGGMFTSSLDADTDGREGSTYVWTPEQLIELLGEDDGRW AAEVYAVTAAGTFEHGSSVLQLPSDPHDAERLQRVSGALSAARRGRAQPGRDDKVVTSWNGLAITALVEA SIALQQPELAQAARRCASVLLDLHVVDGRLRRASLGGVVGDSAAILEDHAMLATGLLALYQLTSEPGWLT SACDLLDTALAHFGDPQRPGRWFDTADDAERLMLRPGDPLDGATASGASSIAEALLTAAHLVADDRAPRY LQAATDTLREHSVLLAHAPRSAGHWLSVAEAAVRGPLQIAVACDDPQSELLAAARRLAPGGAIVVGGRLD SAPLLIGRDRVAGADAAYVCRGRVCDLPVTGTDELAVALPVPG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_0196 | - | - | 100% (674) | transmembrane protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1113 | - | 0.0 | 83.93% (672) | hypothetical protein Mb1113 |
| M. gilvum PYR-GCK | Mflv_2052 | - | 0.0 | 71.86% (661) | hypothetical protein Mflv_2052 |
| M. tuberculosis H37Rv | Rv1084 | - | 0.0 | 83.93% (672) | hypothetical protein Rv1084 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1205 | - | 0.0 | 70.93% (657) | hypothetical protein MAB_1205 |
| M. marinum M | MMAR_4383 | - | 0.0 | 98.52% (674) | transmembrane protein |
| M. avium 104 | MAV_1208 | - | 0.0 | 80.98% (673) | hypothetical protein MAV_1208 |
| M. smegmatis MC2 155 | MSMEG_5259 | - | 0.0 | 71.62% (659) | hypothetical protein MSMEG_5259 |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_4665 | - | 0.0 | 74.62% (658) | Fis family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2052|M.gilvum_PYR-GCK ----MSPPADGPGNLLADATSPYLRQHADNPVHWRQWGADALAEAAARDV
Mvan_4665|M.vanbaalenii_PYR-1 ----MSR-ADGSTNSLARATSPYLRQHADNPVHWQQWAPDALALAAERDV
MSMEG_5259|M.smegmatis_MC2_155 -----------MANLLNRSTSPYLRQHADNPVHWREWTPEALAEAAERDV
MUL_0196|M.ulcerans_Agy99 MTPADSSAGFSGTNTLAQATSPYLRQHADNPVHWQQWTPQALADAAARDV
MMAR_4383|M.marinum_M MTPADSSAGFSGTNTLAQATSPYLRQHADNPVHWQQWTPQALADASARDV
Mb1113|M.bovis_AF2122/97 MSPANP----SGTNTLALATSPYLRQHADNPVHWQQWTPQALAEAAARAV
Rv1084|M.tuberculosis_H37Rv MSPANP----SGTNTLALATSPYLRQHADNPVHWQQWTPQALAEAAARAV
MAV_1208|M.avium_104 MSPADP----SATNTLGRATSPYLRQHADNPVHWQQWTPQALADAAARDV
MAB_1205|M.abscessus_ATCC_1997 ----------MTVNRLGEATSPYLRQHVDNPVHWQQWTPEALAEAQSRDV
* * :********.******::* .:*** * * *
Mflv_2052|M.gilvum_PYR-GCK PILLSIGYAACHWCHVMAHESFSDDEVAAAANRDFVCIKVDREERPDLDA
Mvan_4665|M.vanbaalenii_PYR-1 PILLSIGYAACHWCHVMAHECFEDDEVAAAMNAGFVCIKVDREERPDLDA
MSMEG_5259|M.smegmatis_MC2_155 PILLSIGYAACHWCHVMAHESFEDAEVAALANANYVCIKVDREERPDLDA
MUL_0196|M.ulcerans_Agy99 PILLSIGYAACHWCHVMAHESFEDDEVAAVMNAGFVNIKVDREERPDIDA
MMAR_4383|M.marinum_M PILLSIGYAACHWCHVMAHESFEDDEVAAVMNAGFVNIKVDREERPDIDA
Mb1113|M.bovis_AF2122/97 PILLSVGYAACHWCHVMAHESFDDDEVAAAMNAGFVCIKVDREERPDIDA
Rv1084|M.tuberculosis_H37Rv PILLSVGYAACHWCHVMAHESFDDDEVAAAMNAGFVCIKVDREERPDIDA
MAV_1208|M.avium_104 PILLSVGYAACHWCHVMAHESFEDPDVAAAMNSGFVCVKVDREERPDIDA
MAB_1205|M.abscessus_ATCC_1997 PILLSIGYAACHWCHVMAHESFEDDEVAAVMNAGFVNIKVDREERPDLDA
*****:**************.*.* :*** * .:* :*********:**
Mflv_2052|M.gilvum_PYR-GCK VYMSVTVALTGQGGWPMTCFLTPDGRPFFCGTYYPKVSFLQLLAAVSETW
Mvan_4665|M.vanbaalenii_PYR-1 VYMNATVALTGQGGWPMTCFLTPDGRPFFCGTYYPKASFLQLLAAVVDTW
MSMEG_5259|M.smegmatis_MC2_155 VYMNATVALTGQGGWPMTCFLTPDGRPFFCGTYYPKANFLQLLTAVAETW
MUL_0196|M.ulcerans_Agy99 VYMNATVALTGQGGWPMTCFLTPDGRPFYCGTYYPKAGFLQLLSAVSETW
MMAR_4383|M.marinum_M VYMNATVALTGQGGWPMTCFLTPDGRPFYCGTYYPKAGFLQLLSAVSETW
Mb1113|M.bovis_AF2122/97 VYMNATVALTGQGGWPMTCFLTPNGRPFFCGTYYPKAAFLQLLSAISETW
Rv1084|M.tuberculosis_H37Rv VYMNATVALTGQGGWPMTCFLTPNGRPFFCGTYYPKAAFLQLLSAISETW
MAV_1208|M.avium_104 VYMNATVALTGHGGWPMTCFLTPDGRPFFCGTYYPKDAFLQLLSAVSATW
MAB_1205|M.abscessus_ATCC_1997 VYMNATVAMNGQGGWPMTCFLTPDGRPFYTGTYYPKQGFLQLLSAVREAW
***..***:.*:***********:****: ****** *****:*: :*
Mflv_2052|M.gilvum_PYR-GCK RTRRDEVEQTSDHIAAELRSMATGLPRGSRTVDSAGCDDAVAAVLRDEDV
Mvan_4665|M.vanbaalenii_PYR-1 RTRRADVEETSDKIAAELRSMASGLPRGGPPVAAEVCDDASAAVLRDEDT
MSMEG_5259|M.smegmatis_MC2_155 RDRRGEVERASDQITTELRKMAGGLPAGGPPVSAEMCDHAVASVLGDEDK
MUL_0196|M.ulcerans_Agy99 RERRGEVEEASDHIAGELRSMASGPPGGGPDVAPELCDHAVAVVLGEQDT
MMAR_4383|M.marinum_M RERRGEVEEASDHIAGELRSMASGPPGGGPDVAPELCDHAVAVVLGEQDT
Mb1113|M.bovis_AF2122/97 RERRAEVEQASDHIAAELRSMASGLPGGGPEVAPELCDDAVAGVLREQDT
Rv1084|M.tuberculosis_H37Rv RERRAEVEQASDHIAAELRSMASGLPGGGPEVAPELCDDAVAGVLREQDT
MAV_1208|M.avium_104 RERRGEVEEASDRIAGELRKMTSGLPAGGADLAAALCDEAVAAIIADRDT
MAB_1205|M.abscessus_ATCC_1997 ERRRDEVEEAASSITGQLQAMSGRLPAG-PGVDIALCDTAIAAILPAEDV
. ** :**.::. *: :*: *: * * : ** * * :: .*
Mflv_2052|M.gilvum_PYR-GCK ARGGFSNSPSGAPKFPPSALLEALLRHHERTASPEALATVERTCTAMARG
Mvan_4665|M.vanbaalenii_PYR-1 VDGGFG----AAPKFPPSALLEALLRNHERTGSPAPLAAVSRACEAMARG
MSMEG_5259|M.smegmatis_MC2_155 RHGGFG----GAPKFPPSALLEGLLRHYERTGSAAAVSAVQRTCKAMARG
MUL_0196|M.ulcerans_Agy99 VHGGWG----TAPKFPPSALLEALLRHYERTGSLAALAAVSRTGAAMARG
MMAR_4383|M.marinum_M VHGGWG----TAPKFPPSALLEALLRHYERTGSPAALAAVSRTGAAMARG
Mb1113|M.bovis_AF2122/97 AHGGFG----GAPKFPPSALLEALMRHYERTRSPAALEAVARTGNAMARG
Rv1084|M.tuberculosis_H37Rv AHGGFG----GAPKFPPSALLEALMRHYERTRSPAALEAVARTGNAMARG
MAV_1208|M.avium_104 VHGGFG----GAPKFPPSALLEALLRSYERTGSAAVLQAVAHTGAAMARG
MAB_1205|M.abscessus_ATCC_1997 RFGGFG----GAPKFPPSALLEALLRGYERTGDAPVLAVVARTAAAMARG
**:. ***********.*:* :*** . : .* :: *****
Mflv_2052|M.gilvum_PYR-GCK GIYDQLAGGFARYSVDSSWVVPHFEKMLYDNAQLLRVYAHWARRTADPSA
Mvan_4665|M.vanbaalenii_PYR-1 GIYDQLGGGFARYSVDAAWVVPHFEKMLYDNAQLLRVYAHWARRTGNPLA
MSMEG_5259|M.smegmatis_MC2_155 GIYDQLSGGFARYSVDPYWVVPHFEKMLYDNALLLRVYAHLARRTGSVLA
MUL_0196|M.ulcerans_Agy99 GIYDQLAGGFARYSVDKAWVVPHFEKMLYDNALLLRAYAHWARRTGDELA
MMAR_4383|M.marinum_M GIYDQLAGGFARYSVDKAWVVPHFEKMLYDNALLLRAYAHWARRTGDELA
Mb1113|M.bovis_AF2122/97 GIYDQLGGGFARYSVDGAWVVPHFEKMLYDNALLLRAYAHWARRTGDPLA
Rv1084|M.tuberculosis_H37Rv GIYDQLGGGFARYSVDGAWVVPHFEKMLYDNALLLRAYAHWARRTGDPLA
MAV_1208|M.avium_104 GIYDQLGGGFARYSVDNAWVVPHFEKMLYDNALLLRVYAHWARRTGDPLA
MAB_1205|M.abscessus_ATCC_1997 GIYDQLAGGFARYSVDAAWVVPHFEKMLYDNALLLRFYGHLARRTGDALA
******.********* ************** *** *.* ****.. *
Mflv_2052|M.gilvum_PYR-GCK RRIADETARFLLDDLRRDA---LFVSSLDADTEGVEGLTYVWTPDQLRRV
Mvan_4665|M.vanbaalenii_PYR-1 HRVVDETVRFLIEDLRVGG---MFVSSLDADTAGVEGLTYVWTPGQLCEV
MSMEG_5259|M.smegmatis_MC2_155 RRIASETADFMIAELGDRD---MFTSSLDADAAGSEGSTYVWTPAELRSV
MUL_0196|M.ulcerans_Agy99 CRVAAQTAGFLLDGLAAGG---MFTSSLDADTDGREGSTYVWTPEQLIEL
MMAR_4383|M.marinum_M RRVAAQTAGFLLDGLAAGG---MFTSSLDADTDGREGSTYVWTPEQLIEL
Mb1113|M.bovis_AF2122/97 RRVAAQTARFLLDELGSKAPADMFTSSLDADADGREGSTYVWTPVQLTEV
Rv1084|M.tuberculosis_H37Rv RRVAAQTARFLLDELGSKAPADMFTSSLDADADGREGSTYVWTPVQLTEV
MAV_1208|M.avium_104 ARVTAETARFLLDDLADGD---MFTSSLDADADGREGSTYVWTPAQLTEV
MAB_1205|M.abscessus_ATCC_1997 RRIASETADFLLNELRVGE---LFVSSLDADADGSEGSTYVWTPEQLAEV
*:. :*. *:: * :*.******: * ** ****** :* :
Mflv_2052|M.gilvum_PYR-GCK LGEDDGRWAAEVFEVTSDGTFEDGQSVLQLLRDPDDPERFERVRIALRAE
Mvan_4665|M.vanbaalenii_PYR-1 LGEGDGRWAAELFGVTAAGTFEGGASVLQMRADPDDADRFVRVRDALRAA
MSMEG_5259|M.smegmatis_MC2_155 LGDDDGIWAAAVFGVTDEGTFEHGASVLQLPATPDDPARFETIRTTLLAA
MUL_0196|M.ulcerans_Agy99 LGEDDGRWAAEVYAVTAAGTFEHGSSVLQLPSDPHDAERLQRVSGALSAA
MMAR_4383|M.marinum_M LGEDDGRWAAEVYAVTAAGTFEHGASVLQLPSDPHDAERLQRVSGALSAA
Mb1113|M.bovis_AF2122/97 LGGDDGRWAAEVFGVTEAGTFEHGTSVLQLPADPDDAARLDRVRAALLVA
Rv1084|M.tuberculosis_H37Rv LGGDDGRWAAEVFGVTEAGTFEHGTSVLQLPADPDDAARLDRVRAALLVA
MAV_1208|M.avium_104 LGPDDGRWAAAVFGVTETGTFEHGSSVLRLPADPPDTPRFDRVRAALLAA
MAB_1205|M.abscessus_ATCC_1997 LGPEDGAWAATLFEVTPTGTFERGSSVLQLLRDPEDAARWQRVRQALLAA
** ** *** :: ** **** * ***:: * *. * : :* .
Mflv_2052|M.gilvum_PYR-GCK RRARPQPARDDKVIAAWNGLAITALAEAAFALGRPEYFSAAVDCAQALLD
Mvan_4665|M.vanbaalenii_PYR-1 RLTRPQPTRDDKVVTAWNGLAITALVEAS-VLDRPEYLSAAIQCARTLLD
MSMEG_5259|M.smegmatis_MC2_155 RAARPQPARDDKVVTAWNGFAVTALAEASVALQRPELLDAASRCARRLID
MUL_0196|M.ulcerans_Agy99 RRGRAQPGRDDKVVTSWNGLAITALVEASIALQQPELAQAARRCASVLLD
MMAR_4383|M.marinum_M RRGRAQPGRDDKVVTSWNGLAITALVEASIALQQPELAQAARRCARVLLD
Mb1113|M.bovis_AF2122/97 RLARAQPARDDKVVTSWNGLAITALAEASVALDDPALAHAARRCATRLLD
Rv1084|M.tuberculosis_H37Rv RLARAQPARDDKVVTSWNGLAITALAEASVALDDPALAHAARRCATRLLD
MAV_1208|M.avium_104 RRSRIQPGRDDKVVTSWNGLAITAFTEASVALDDLGLADAARRCARSVLD
MAB_1205|M.abscessus_ATCC_1997 RLVRVQPGRDDKAVTAWNGLAITALVEASVALDRDDLLEAAGGCAAALLE
* * ** ****.:::***:*:**:.**: .* ** ** :::
Mflv_2052|M.gilvum_PYR-GCK LHIVDGRLRRSSLGGVVGDGAAILEDHAALATALLTLHQGTGERRWLDAA
Mvan_4665|M.vanbaalenii_PYR-1 AHLVDGRLRRSSLGGVVGDSMAVLEDHAALATGLLALHQATGERVWLQEA
MSMEG_5259|M.smegmatis_MC2_155 LHMVDGRLRRASLGGAVGASAGILEDHAALATALLTLYQQTG--QWLPEA
MUL_0196|M.ulcerans_Agy99 LHVVDGRLRRASLGGVVGDSAAILEDHAMLATGLLALYQLTSEPGWLTSA
MMAR_4383|M.marinum_M LHVVDGRLRRACLGGVVGDSAAILEDHAMLATGLLALYQLTSEPGWLTSA
Mb1113|M.bovis_AF2122/97 LHVVDGRLRRASLGGVVGDSAAILEDHAMLATGLLALYQLTSEGAWLTAA
Rv1084|M.tuberculosis_H37Rv LHVVDGRLRRASLGGVVGDSAAILEDHAMLATGLLALYQLTSEGAWLTAA
MAV_1208|M.avium_104 LHVVDGRLRRASLGGVVGDSAAILEDYAMLATGLLALYQLSAEDSWLTAA
MAB_1205|M.abscessus_ATCC_1997 LHLRDGRLRRASLGGQVSEGDGVLEDYGTLATGLLSLYQVTGQWRWREAA
*: ******:.*** *. . .:***:. ***.**:*:* :. * *
Mflv_2052|M.gilvum_PYR-GCK TRLLNLALDHFADPDEPGRWYDVADDAERLVVRPSDPMDGATPSGASLVA
Mvan_4665|M.vanbaalenii_PYR-1 TGLLDLALDHFSDSAEVGRWFDVADDAEQLMLRPSDPLDGATPSGASLIA
MSMEG_5259|M.smegmatis_MC2_155 RHLLDLALEHFADPEQPGRWYDTADDAETLMVRPADPIDGATPAGASLIA
MUL_0196|M.ulcerans_Agy99 CDLLDTALAHFGDPQRPGRWFDTADDAERLMLRPGDPLDGATASGASSIA
MMAR_4383|M.marinum_M CDLLDTALAHFGDPQRPGRWFDTADDAERLMLRPGDPLDGATPSGASSIA
Mb1113|M.bovis_AF2122/97 TGLLDTAVAHFGDPQRPGRWFDTADDAERLMLRPSDPLDGATPSGASSIA
Rv1084|M.tuberculosis_H37Rv TGLLDTAVAHFGDPQRPGRWFDTADDAERLMLRPSDPLDGATPSGASSIA
MAV_1208|M.avium_104 TDLLDTALAHFADPQRPGRWFDTADDAERLMLRPADPLDGATPSGASSVT
MAB_1205|M.abscessus_ATCC_1997 AQLLDAALDHFADPESPGAWFDVADDAEQLVLRPSDPLDGATPSGASSVT
**: *: **.*. * *:*.***** *::**.**:****.:*** ::
Mflv_2052|M.gilvum_PYR-GCK EALQVAAHLADDG-ADRYAAAADAALSSAAVLLERAPRSAGHWLAVAEAA
Mvan_4665|M.vanbaalenii_PYR-1 EALQLAAHLAPEAAAQRYAAAAEATMAGATVLLARVPRSAGHWLAVAEAA
MSMEG_5259|M.smegmatis_MC2_155 EALQLAAYLTGSS---RYAEAAQATLATAVPILTRAARSGGHWLAVAEAQ
MUL_0196|M.ulcerans_Agy99 EALLTAAHLVADDRAPRYLQAATDTLREHSVLLAHAPRSAGHWLSVAEAA
MMAR_4383|M.marinum_M EALLTAAHLVADDRAPRYLQAATETLREHSVLLARAPRSAGHWLSVAEAA
Mb1113|M.bovis_AF2122/97 EALLTAGHVVDGARAERYWQLAADTLRAHAVLLARAPRSAGHWLAVAEAV
Rv1084|M.tuberculosis_H37Rv EALLTAGHVVDGARAERYWQLAADTLRAHAVLLARAPRSAGHWLAVAEAV
MAV_1208|M.avium_104 EALLTAAHLVGGERAERYLRAATDALRAQAVLLERAPRTAGHWLAVAEAA
MAB_1205|M.abscessus_ATCC_1997 EALLTAGYLLEDP---RYREAAYASLAAASMALARAPRSAGHWLAVAEAA
*** *.:: ** * :: * :..*:.****:****
Mflv_2052|M.gilvum_PYR-GCK VRGPIQIAVACEGPDSALLAAARALAPGGAVVIGGVTDSSALLRDRPRVR
Mvan_4665|M.vanbaalenii_PYR-1 VRGPIQIAVAG-GADSALLAAARRLAPGGAVVVGGEVNSSELLRDRPRVD
MSMEG_5259|M.smegmatis_MC2_155 LRGPIQIAVAC-EPSSELLAAARTLAPGGAVVVGGAVDSSELLRGRDRVD
MUL_0196|M.ulcerans_Agy99 VRGPLQIAVACDDPQSELLAAARRLAPGGAIVVGGRLDSAPLLIGRDRVA
MMAR_4383|M.marinum_M VRGPLQIAVACDDPQSELLAAARRLAPGGAIVVGGRLDSAPLLIGRDRVA
Mb1113|M.bovis_AF2122/97 VRGPLQIAVACDLPRSSLLADARRLAPGGAIVVGGAAGSSALLVGRDRVA
Rv1084|M.tuberculosis_H37Rv VRGPLQIAVACDLPRSSLLADARRLAPGGAIVVGGAAGSSALLVGRDRVA
MAV_1208|M.avium_104 VRGPLQIAVACDPARSALLADARRLAPGGAIVVGGPRDSSELLSGRDRVA
MAB_1205|M.abscessus_ATCC_1997 VRGPIQVAVACDAETSALLRSARLLAPGGAIVVGGVKDSSELLRDRGQIG
:***:*:*** * ** ** ******:*:** .*: ** .* ::
Mflv_2052|M.gilvum_PYR-GCK GADAAYVCRGRACDLPVTTAGELAAALGCSV-
Mvan_4665|M.vanbaalenii_PYR-1 GADAAYVCRGRVCDLPVTTVEDLATALGASV-
MSMEG_5259|M.smegmatis_MC2_155 GADAAYVCRGTVCDLPVTTVGDLADALGVAV-
MUL_0196|M.ulcerans_Agy99 GADAAYVCRGRVCDLPVTGTDELAVALPVPG-
MMAR_4383|M.marinum_M GADAAYVCRGRVCDLPVTGTDELAAALPVPG-
Mb1113|M.bovis_AF2122/97 GADAAYVCRGRVCDLPVTSAAELATALGVPG-
Rv1084|M.tuberculosis_H37Rv GADAAYVCRGRVCDLPVTSAAELATALGVPG-
MAV_1208|M.avium_104 GADAAYVCRGRVCDLPVTRTPELAAALGAPAP
MAB_1205|M.abscessus_ATCC_1997 DADAAYVCRGTVCDLPVTGTQQLDAALGR---
.********* .****** . :* **