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RAPSITGVVLAAGGSRRLGTPKQLLSYRDTTLLGATLRVARGAGFDQLIVTLGGAAQRVRALVPLDEAEV VTVEDFGAGCSASLRVALGRVDPQSAGIVLMLGDQPGVDPATVARLVGQGPGCDLMVCRYNDGIGHPFWF SRRLFGELTQLHGDKGVWKLIQSGRHPVRELVVDDSVPLDVDTRDDYRRLVESVP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_0113 | - | - | 100% (196) | hypothetical protein MUL_0113 |
| M. ulcerans Agy99 | MUL_0589 | - | 1e-13 | 36.54% (156) | hypothetical protein MUL_0589 |
| M. ulcerans Agy99 | MUL_4637 | glmU | 3e-06 | 33.90% (118) | UDP-N-acetylglucosamine pyrophosphorylase GlmU |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0378c | - | 8e-79 | 73.20% (194) | hypothetical protein Mb0378c |
| M. gilvum PYR-GCK | Mflv_4787 | - | 9e-12 | 32.24% (183) | hypothetical protein Mflv_4787 |
| M. tuberculosis H37Rv | Rv0371c | - | 8e-79 | 73.20% (194) | hypothetical protein Rv0371c |
| M. leprae Br4923 | MLBr_00249 | glmU | 2e-05 | 28.97% (145) | bifunctional N-acetylglucosamine-1-phosphate |
| M. abscessus ATCC 19977 | MAB_2937c | - | 2e-05 | 30.57% (157) | hypothetical protein MAB_2937c |
| M. marinum M | MMAR_0659 | - | 1e-109 | 98.47% (196) | hypothetical protein MMAR_0659 |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_1806 | - | 1e-12 | 31.32% (182) | hypothetical protein MSMEG_1806 |
| M. thermoresistible (build 8) | TH_0242 | - | 1e-10 | 29.44% (180) | CONSERVED HYPOTHETICAL PROTEIN |
| M. vanbaalenii PYR-1 | Mvan_1662 | - | 1e-09 | 31.32% (182) | hypothetical protein Mvan_1662 |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_0113|M.ulcerans_Agy99 ----MRAPSITGVVLAAGGSRRLG--TPKQLLSYRDTTLLGATLRVARGA
MMAR_0659|M.marinum_M ----MRAPSITGVVLAAGGSRRLG--TPKQLLAYRDTTLLGATLRVARGA
Mb0378c|M.bovis_AF2122/97 ----MTATQITGVVLAAGRSNRLG--TPKQLLPYRDTTVLGATLDVARQA
Rv0371c|M.tuberculosis_H37Rv ----MTATQITGVVLAAGRSNRLG--TPKQLLPYRDTTVLGATLDVARQA
MSMEG_1806|M.smegmatis_MC2_155 ---MSEPPVVAGVVLAAGAGTRFG--MPKVLA--AEGDWLKTAVRSLVEG
TH_0242|M.thermoresistible__bu -MGVTTTSTAAGVVLAAGAGTRFG--MPKILA--AEGLWLKIAVSALSGG
Mflv_4787|M.gilvum_PYR-GCK ---------MTGVVLAAGAGTRFG--MPKVLA--DGGEWLRRSVAAVSDG
Mvan_1662|M.vanbaalenii_PYR-1 ----MTQELSTGVVLAAGAGTRFG--MPKVLG--GDGDWLRRSVAALHDG
MAB_2937c|M.abscessus_ATCC_199 MEPDPTAGVVVGAVLAAGAGNRYG--MPKILA--ANGRWLELAVTALDRG
MLBr_00249|M.leprae_Br4923 ---MTFRGDTAVLVLAAGPGSRMRSDTPKVLHTIAGRSMLSHSLHAITKL
. ***** . * ** * * ::
MUL_0113|M.ulcerans_Agy99 GFDQLIVTLGGAAQRVRALVPLDE-----AEVVTVEDFGAGCSASLRVAL
MMAR_0659|M.marinum_M GFDQLIVTLGGAAQRVRALVPLDE-----AEVVTVEDFGTGCSASLRVAL
Mb0378c|M.bovis_AF2122/97 GFDQLILTLGGAASAVRAAMALDG-----TDVVVVEDVERGCAASLRVAL
Rv0371c|M.tuberculosis_H37Rv GFDQLILTLGGAASAVRAAMALDG-----TDVVVVEDVERGCAASLRVAL
MSMEG_1806|M.smegmatis_MC2_155 GCAHVVVVLGAAVVDVPQP----------AQAVVATDWSDGLSASLRAGV
TH_0242|M.thermoresistible__bu GCGDVVVVLGAAIVDVPAP----------ARAVVAQDWSRGLSASLRAGI
Mflv_4787|M.gilvum_PYR-GCK GCDDVVVVLGAAVVDVPAP----------ARAVVADDWRDGLSASVRAGV
Mvan_1662|M.vanbaalenii_PYR-1 GCGDVVVVLGAAIVDVPAP----------ARAVVTADWADGLSASVRAGV
MAB_2937c|M.abscessus_ATCC_199 GCEEVYVTQGAVSVEMPSP----------AHGIEVARWRDGVSESVRAVL
MLBr_00249|M.leprae_Br4923 APQHLVVVLGHEHQRIAPLVAELADTLERTIDVALQDRPRGTGHAVFCGL
. .: :. * : : : * . :: :
MUL_0113|M.ulcerans_Agy99 GRVDP--QSAGIVLMLGDQPGVDPATVARLVGQGP----GCDLMVCRYND
MMAR_0659|M.marinum_M GRVDP--QSAGIVLMLGDQPGVDPATVARLVGQGP----GCDLMVCRYND
Mb0378c|M.bovis_AF2122/97 ARVHP--RATGIVLMLGDQPQVAPATLRRIIDVGP----ATEIMVCRYAD
Rv0371c|M.tuberculosis_H37Rv ARVHP--RATGIVLMLGDQPQVAPATLRRIIDVGP----ATEIMVCRYAD
MSMEG_1806|M.smegmatis_MC2_155 GAAAR-TGADLIVFRLVDTPDIGGDVIARVAAAAG----ESGLARATYDG
TH_0242|M.thermoresistible__bu TALG--DDADLAVIHTVDTPDIGADVVRRVLTAARST--PSGLARAWFGD
Mflv_4787|M.gilvum_PYR-GCK RAAS---GADFVVLTTVDTPDVGAAAVRRVLTAARES--ASGLVRARYGG
Mvan_1662|M.vanbaalenii_PYR-1 RAAG--DAADFVVLTTVDTPDVGAAAVRRVLAAARAS--TSGLARAYYDG
MAB_2937c|M.abscessus_ATCC_199 ELVHARTDVVGVLIHLVDLPSVGPEVVRMVLRASGGR--RSALVRATFAG
MLBr_00249|M.leprae_Br4923 SALPD-DYGGIVVVTSGDTPLLDANTLAELIATHNATSAAVTVLTTTFSD
:. * * : .: : : : .
MUL_0113|M.ulcerans_Agy99 GIGHPFWFSRRLFGELTQ-LHGDKGVWK----------------------
MMAR_0659|M.marinum_M GIGHPFWFSRRLFGELTQ-LHGDKGVWK----------------------
Mb0378c|M.bovis_AF2122/97 GVGHPFWFSRTVFGELAR-LHGDKGVWK----------------------
Rv0371c|M.tuberculosis_H37Rv GVGHPFWFSRTVFGELAR-LHGDKGVWK----------------------
MSMEG_1806|M.smegmatis_MC2_155 RPGHPVVIARRHWPELLRVVHGDEGAKP----------------------
TH_0242|M.thermoresistible__bu RPGHPVVVGRQHWPALLRSLHGDEGAKR----------------------
Mflv_4787|M.gilvum_PYR-GCK RPGHPVVIARRHLPQLLDSLSGDDGAGP----------------------
Mvan_1662|M.vanbaalenii_PYR-1 RPGHPVVIARRHWPALLDALAGDVGAGP----------------------
MAB_2937c|M.abscessus_ATCC_199 RPGHPVYLGSEHVGPVLSALAADRGAGP----------------------
MLBr_00249|M.leprae_Br4923 PLGYGRILRTQDNEVMAIIEHADASPSQREIREVNAGVYAFDITALRSAL
*: . : .* .
MUL_0113|M.ulcerans_Agy99 --------------------LIQSGRHPVRELVVDDSVPLDVDTRDDYRR
MMAR_0659|M.marinum_M --------------------LIQSGRHPVRELVVDDSVPLDVDTWDDYRR
Mb0378c|M.bovis_AF2122/97 --------------------LVHSGRHPVRELAVDGCVPLDVDTWDDYRR
Rv0371c|M.tuberculosis_H37Rv --------------------LVHSGRHPVRELAVDGCVPLDVDTWDDYRR
MSMEG_1806|M.smegmatis_MC2_155 --------------------FLRGRTDVVAVECGDLATGADIDVSP----
TH_0242|M.thermoresistible__bu --------------------FLRGRSDVVRVDCSDLAGGRDIDTPNSGAD
Mflv_4787|M.gilvum_PYR-GCK --------------------FLKARADVVAVECGDLSSGRDIDTR-----
Mvan_1662|M.vanbaalenii_PYR-1 --------------------FLAGRDDVVAVECADLGTGRDIDAR-----
MAB_2937c|M.abscessus_ATCC_199 --------------------YLAARTDVIEVPCEHLADGADHDYRP----
MLBr_00249|M.leprae_Br4923 IRLNSNNTQQELYLTDVISILRREGQKVNAQHIDDNALVAGVNNRVQLAE
. . . :
MUL_0113|M.ulcerans_Agy99 LVESVP--------------------------------------------
MMAR_0659|M.marinum_M LVESVP--------------------------------------------
Mb0378c|M.bovis_AF2122/97 LLESVPS-------------------------------------------
Rv0371c|M.tuberculosis_H37Rv LLESVPS-------------------------------------------
MSMEG_1806|M.smegmatis_MC2_155 --------------------------------------------------
TH_0242|M.thermoresistible__bu AR------------------------------------------------
Mflv_4787|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1662|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_2937c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_00249|M.leprae_Br4923 LSAELNRRIVATHQVAGVTIIDPATTWIDIDVTIGNDTVIHPGTQLLGRT
MUL_0113|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0659|M.marinum_M --------------------------------------------------
Mb0378c|M.bovis_AF2122/97 --------------------------------------------------
Rv0371c|M.tuberculosis_H37Rv --------------------------------------------------
MSMEG_1806|M.smegmatis_MC2_155 --------------------------------------------------
TH_0242|M.thermoresistible__bu --------------------------------------------------
Mflv_4787|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1662|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_2937c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_00249|M.leprae_Br4923 QIGECCVIGPDTTLTDVLVSQRATVVRTHGTSSTIGAGAMVGPFTYLRPG
MUL_0113|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0659|M.marinum_M --------------------------------------------------
Mb0378c|M.bovis_AF2122/97 --------------------------------------------------
Rv0371c|M.tuberculosis_H37Rv --------------------------------------------------
MSMEG_1806|M.smegmatis_MC2_155 --------------------------------------------------
TH_0242|M.thermoresistible__bu --------------------------------------------------
Mflv_4787|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1662|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_2937c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_00249|M.leprae_Br4923 TVLGTKGKLGAFVETKNSTIGTGAKVPHLTYVGDADIGEHSNIGASSVFV
MUL_0113|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0659|M.marinum_M --------------------------------------------------
Mb0378c|M.bovis_AF2122/97 --------------------------------------------------
Rv0371c|M.tuberculosis_H37Rv --------------------------------------------------
MSMEG_1806|M.smegmatis_MC2_155 --------------------------------------------------
TH_0242|M.thermoresistible__bu --------------------------------------------------
Mflv_4787|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1662|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_2937c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_00249|M.leprae_Br4923 NYDGTAKQRTTIGSHVRTGSDTKFVAPVTVGDGAYTGAGTVVRNDVPPGA
MUL_0113|M.ulcerans_Agy99 ----------------------------------------------
MMAR_0659|M.marinum_M ----------------------------------------------
Mb0378c|M.bovis_AF2122/97 ----------------------------------------------
Rv0371c|M.tuberculosis_H37Rv ----------------------------------------------
MSMEG_1806|M.smegmatis_MC2_155 ----------------------------------------------
TH_0242|M.thermoresistible__bu ----------------------------------------------
Mflv_4787|M.gilvum_PYR-GCK ----------------------------------------------
Mvan_1662|M.vanbaalenii_PYR-1 ----------------------------------------------
MAB_2937c|M.abscessus_ATCC_199 ----------------------------------------------
MLBr_00249|M.leprae_Br4923 LAVSVSPQRNIENWVQRKRPGSAAAQAAEKASTRTGKQSQQKSEPD