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SVTTFADPQDVVRRFDAQNYLLDTGTASAIYLAVTLGRPLLLEGEPGVGKTTAAKALAAVLDTSLIRLQC YEGLTANEALYDWNYQHQLLSIRLAEARGADISEADLYSEAYLVDRPILQCVRHRGSTPPVLLIDEIDRA DDEFEALLLEFLGEAAVTVPELGTFVAPLPPIAVLTSNRSRDLYDALRRRCLYHWIDYPEPARAAAIVRR TVPGASAALIEHATQFVGSARDLDLDKPPGVAETIGWVAALVSLGVADLVDASALASLGALAKTPDARTL IRDALTEYSRT*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_0112 | - | - | 100% (292) | membrane oxidoreductase |
| M. ulcerans Agy99 | MUL_3695 | - | 2e-60 | 45.05% (273) | hypothetical protein MUL_3695 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0377c | - | 1e-138 | 85.96% (292) | oxidoreductase |
| M. gilvum PYR-GCK | Mflv_2645 | - | 6e-61 | 46.10% (269) | ATPase |
| M. tuberculosis H37Rv | Rv0370c | - | 1e-137 | 85.62% (292) | oxidoreductase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1619 | - | 1e-59 | 44.61% (269) | hypothetical protein MAB_1619 |
| M. marinum M | MMAR_0660 | - | 1e-162 | 98.97% (292) | membrane oxidoreductase |
| M. avium 104 | MAV_1748 | - | 1e-62 | 47.21% (269) | ATPase associated with various cellular activities |
| M. smegmatis MC2 155 | MSMEG_0748 | - | 1e-126 | 79.17% (288) | ATPase |
| M. thermoresistible (build 8) | TH_3691 | - | 1e-126 | 79.31% (290) | PUTATIVE succinate dehydrogenase subunit A |
| M. vanbaalenii PYR-1 | Mvan_3933 | - | 1e-62 | 46.55% (275) | ATPase |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_0112|M.ulcerans_Agy99 --------MS----------VTTFADPQDVVRRFDAQNYLLDTGTASAIY
MMAR_0660|M.marinum_M --------MS----------VTTFADPQDVVRRFDAQNYLLDTGTASAIY
Mb0377c|M.bovis_AF2122/97 ---------------------MTFASPDDVIRRFDEQNYLLDTGTASAIY
Rv0370c|M.tuberculosis_H37Rv ---------------------MTFASPDDVIRRFDEQNYLLDTGTASAIY
TH_3691|M.thermoresistible__bu ---MPTDVAR----------GAEFADVDDVIRRFDTADYLLDTGTAAAIY
MSMEG_0748|M.smegmatis_MC2_155 MRMAAEPGAA----------VTGFGGVDDVVRRFDAHDYLLDEGTATAIY
Mflv_2645|M.gilvum_PYR-GCK ---MSVPASI----------QPLFADIDDVARRLAETGYLPDTATATAVF
Mvan_3933|M.vanbaalenii_PYR-1 ---MSVPAQT----------VPLFADIDDVARRLAETGYLPDTATATAVF
MAV_1748|M.avium_104 ---MSVPARP----------RPLFADIDDVSRRLAETGYLPDTATATAVF
MAB_1619|M.abscessus_ATCC_1997 ---MSDPLRPSGSSQSRTQTAPLFTSIDDVTTRLAETGYLADTATATAVF
* . :** *: .** * .**:*::
MUL_0112|M.ulcerans_Agy99 LAVTLGRPLLLEGEPGVGKTTAAKALAAVLDTSLIRLQCYEGLTANEALY
MMAR_0660|M.marinum_M LAVTLGRPLLLEGEPGVGKTTAAKALAAVLDTSLIRLQCYEGLTANEALY
Mb0377c|M.bovis_AF2122/97 LAVTLGRPLLLEGEPGVGKTTAAKTLAVVLDTTLIRLQCYEGLTANEALY
Rv0370c|M.tuberculosis_H37Rv LAVTLGRPLLLEGEPGVGKTTAAKTLAVVLDTTLIRLQCYEGLTANEALY
TH_3691|M.thermoresistible__bu LSTTLGRPLLLEGEPGVGKTTAAKTLAVVCDTPLIRLQCYEGLTAAEALY
MSMEG_0748|M.smegmatis_MC2_155 LAVSLGRPLLLEGEPGVGKTTAAKTLAAVLGTPLIRLQCYEGLTASEALY
Mflv_2645|M.gilvum_PYR-GCK LADRLGKPLLVEGPAGVGKTELARAIAQSTGSGLVRLQCYEGVDESRALY
Mvan_3933|M.vanbaalenii_PYR-1 LADRLGKPLLVEGPAGVGKTELARAIAQSTGSELVRLQCYEGVDESRALY
MAV_1748|M.avium_104 LADRLGKPLLVEGPAGVGKTELARAVAQATGSGLVRLQCYEGVDEARALY
MAB_1619|M.abscessus_ATCC_1997 LADRLGKPLLVEGPAGVGKTELARAVAHTTGSGLVRLQCYEGVDEARALY
*: **:***:** .***** *:::* .: *:*******: .***
MUL_0112|M.ulcerans_Agy99 DWNYQHQLLSIRLAEARG---ADISEADLYSEAYLVDRPILQCVRHRGST
MMAR_0660|M.marinum_M DWNYQHQLLSIRLAEARG---ADISEADLYSEAYLVDRPILQCVRHRGST
Mb0377c|M.bovis_AF2122/97 DWNYQRQLLSIRLAEARGKGISDISEADLYTEAYLVDRPILRCVRHRGPT
Rv0370c|M.tuberculosis_H37Rv DWNYQRQLLSIRLAEARGKGISDISEADLYTEAYLVDRPILRCVRHRGPT
TH_3691|M.thermoresistible__bu DWNHQRQLLSIRLAEARH---TGIDEAELYTETYLVNRPILAAVRHTGPR
MSMEG_0748|M.smegmatis_MC2_155 DWNYQRQLLSIRLAEARGG--EHLDEAALYTESYLVDRPILQCVRHRGPS
Mflv_2645|M.gilvum_PYR-GCK EWNHAKQILRIQAGHG----DWDQTRDDVFSEEFLLTRPLLTAIRRTEPT
Mvan_3933|M.vanbaalenii_PYR-1 EWNHAKQILRIQAGQGEGA-DWDRTKDDVFSEEFLLTRPLLTAIRRTEPT
MAV_1748|M.avium_104 EWNHAKQILRIQAGSG----DWDQTKTDVFSEEFLLQRPLLTAIRRTEPT
MAB_1619|M.abscessus_ATCC_1997 EWNHAKQILRIQAGSG----DWDETKTDVFAEEFLLSRPLLTAIRREDPT
:**: :*:* *: . . . :::* :*: **:* .:*: .
MUL_0112|M.ulcerans_Agy99 PPVLLIDEIDRADDEFEALLLEFLGEAAVTVPELGTFVAPLPPIAVLTSN
MMAR_0660|M.marinum_M PPVLLIDEIDRADDEFEALLLEFLGEAAVTVPELGTFVAPLPPIAVLTSN
Mb0377c|M.bovis_AF2122/97 PPVLLIDEIDRADDEFEALLLEFLGESAVTVPELGTFLAECPPIAVLTSN
Rv0370c|M.tuberculosis_H37Rv PPVLLIDEIDRADDEFEALLLEFLGESAVTVPELGTFLAECPPIAVLTSN
TH_3691|M.thermoresistible__bu PPVLLIDEIDRADDEFEALLLEFLGESAVTVPELGTFTAERPPVVVLTSN
MSMEG_0748|M.smegmatis_MC2_155 SPVLLVDEIDRADDEFEALLLEFLGEAAVTVPELGTFVAERPPVVVLTSN
Mflv_2645|M.gilvum_PYR-GCK --VLLIDETDKADIEIEGLLLEVLSDFAVTVPELGTITAERRPLVVLTSN
Mvan_3933|M.vanbaalenii_PYR-1 --VLLIDETDKADIEIEGLLLEVLSDFAVTVPELGTITAERRPLVVLTSN
MAV_1748|M.avium_104 --VLLIDETDKADIEIEGLLLEVLSDFAVTVPELGTLTAERPPFVVLTSN
MAB_1619|M.abscessus_ATCC_1997 --VLLIDETDKADIEIEGLLLEVLSDFAVTIPELGTIAASRKPFVLLTSN
***:** *:** *:*.****.*.: ***:*****: * *..:****
MUL_0112|M.ulcerans_Agy99 RSRDLYDALRRRCLYHWIDYPEPARAAAIVRRTVPGASAALIEHATQFVG
MMAR_0660|M.marinum_M RSRDLHDALRRRCLYHWIDYPEPARAAAIVRRTVPGASAALIEHATQFVG
Mb0377c|M.bovis_AF2122/97 RSRDLHDALRRRCLYHWIDYPEPDRAAAIVRRTVPGATAPLIENATQFVC
Rv0370c|M.tuberculosis_H37Rv RSRDLHDALRRRCLYHWIDYPGPDRAAAIVRRTVPGATAPLIENATQFVC
TH_3691|M.thermoresistible__bu RSRDLHDALRRRCVYHWIDYPEPARAVAIVRRTVPGASSALIEQAAGFVG
MSMEG_0748|M.smegmatis_MC2_155 RSRDLHDALRRRCLYHWIEYPQRAQAVAIVRRTVPGATDALIDSAVQFVS
Mflv_2645|M.gilvum_PYR-GCK ATRELSEALKRRCLFLHIDFPDPDLERRILLSRVPELPERLAEELVRIIG
Mvan_3933|M.vanbaalenii_PYR-1 ATRELSEALKRRCLFLHIDFPDPDLERRILLSRVPELPERLAEELVRIIG
MAV_1748|M.avium_104 ATRELSEALKRRCLFLHIDFPSPDLERRILLSRVPELPAHLADELVRIIG
MAB_1619|M.abscessus_ATCC_1997 ATRELSEALKRRCLFLHIDFPDAELERRILLKRVPELPASLAEELVRIIG
:*:* :**:***:: *::* *: ** . * : . ::
MUL_0112|M.ulcerans_Agy99 SARDLDLDKPPGVAETIGWVAALVSLGVADLVDAS---ALASLGALAKTP
MMAR_0660|M.marinum_M SARDLDLDKPPGVAETIDWVAALVSLGVADLVDAS---ALASLGALAKTP
Mb0377c|M.bovis_AF2122/97 TARDLDLDKPPGVAETIDWVAALVALGVADLTAADSSPALASLGALAKTP
Rv0370c|M.tuberculosis_H37Rv TARDLDLDKPPGVAETIDWVAALVALGVADLTAADSSPALASLGALAKTP
TH_3691|M.thermoresistible__bu VARTLDLDKPPGVAETIDWVAALAALGVADLVDTDTERALQSIGALAKTP
MSMEG_0748|M.smegmatis_MC2_155 AARELDLDKPPGVAETIDWVAALVALRVGDLVDPA---ALGTLGALAKTP
Mflv_2645|M.gilvum_PYR-GCK VLRGMQLKKLPSVAETIDWARTVLALGMDTIDDEV---IAATLGVVLKHQ
Mvan_3933|M.vanbaalenii_PYR-1 VLRGMALKKLPSVAETIDWGRTLLALGMDTVDDEV---IAATLGVVLKHQ
MAV_1748|M.avium_104 VLRGMQLKKVPSIAETIDWGRTLLALGLDTIDDAV---VAATLGVVLKHQ
MAB_1619|M.abscessus_ATCC_1997 VLRNMQLKKVPSVAETIDWGRTILALGLDTLDDAV---IASTLGVVLKHH
* : *.* *.:****.* :: :* : : ::*.: *
MUL_0112|M.ulcerans_Agy99 DARTLIRDALTEYSRT---
MMAR_0660|M.marinum_M DDRTLIRDALTEYSRT---
Mb0377c|M.bovis_AF2122/97 DDRTQIRDAYQAFTECSHA
Rv0370c|M.tuberculosis_H37Rv DDRTQIRDAYQAFTECSHA
TH_3691|M.thermoresistible__bu DDRDLIGTALTGYSPT---
MSMEG_0748|M.smegmatis_MC2_155 DDSGLMRDALLDLTN----
Mflv_2645|M.gilvum_PYR-GCK SDQIKAAGELRLN------
Mvan_3933|M.vanbaalenii_PYR-1 SDQIKASGELRLN------
MAV_1748|M.avium_104 SDQQRATGELRLN------
MAB_1619|M.abscessus_ATCC_1997 SDQQRAAGELRLN------
.