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VYQQVLDPVVNSLAWSAAVAAIPLLLLFVLLGVFKMTAWKASLISLAVSIAVAVLVYGMPIGQSLLAASE GAAFGFFPILWIVINAIWVYQMTVETGHFDVLRRSFSSISDDQRIQAIIITFSFGALLEALAGFGTPVAV TSVMLMALGFRPLKAAVLALVANTAPVAFGAMATPIITLGKVTELDFDTLGAMVGRQTPILAVFVPLALV AIVDGRRGMRAVWPAAVVCGVVFAVAQYATSNFLSVPLADVVASLASAAAVVALVRVWQPANTYTEVAEP AAVTTHTGPPPHGRSGGTGGSADLPEPDQNVEDARADVVKAYAPYGIIIGVFVICQIPAVKSLLDSATFA GNWPGLNVVDVNGDPSSMTKFTLNLLTTPGTQMLFAGVLTMVALKLSVSRAARAYWTTLHQLRWAILTVM AVLALAFVMNLSGQTITLGTFMAAAGGAFALLSPILGWLGVAVTGSDTSANSLFGALQVTAAYQAGLSDV LMAASNSSGGVLGKMVSPQNLAIAAAAVGLNGREGDIFRRVVLWSLGFLVLLCALTALQSSPVLSWMVPS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_6826 | - | - | 100% (560) | L-lactate permease |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | - | - | - | - | - |
| M. thermoresistible (build 8) | TH_4429 | - | 2e-05 | 27.14% (409) | PUTATIVE - |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_1934 | - | 5e-05 | 25.28% (269) | TRAP transporter, 4TM/12TM fusion protein |
CLUSTAL 2.0.9 multiple sequence alignment
TH_4429|M.thermoresistible__bu VTTPVGSIRIDLSIDGSNLGDEITAAVQKHVKAALGELNEVLAEVQAQME
MSMEG_6826|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_1934|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4429|M.thermoresistible__bu STSRASASAATGVGQAGKAAREATGGMSDMQQASQAAAQATKTAGDAARA
MSMEG_6826|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_1934|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4429|M.thermoresistible__bu AGSGMDDMGRASDGAADRTSKAGRAASQASGEFGRFSRAAERASAVSKQL
MSMEG_6826|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_1934|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4429|M.thermoresistible__bu GSGVGQAASGFVRAGDAVLGAVGKFAKWTGIGAAVSGAIGGVAGSFSVLQ
MSMEG_6826|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_1934|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4429|M.thermoresistible__bu LGMNRLTSIENARSTLQGLGHDARSVEGIMDSALTAVKGTAFGLGEAATV
MSMEG_6826|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_1934|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4429|M.thermoresistible__bu AASAVAAGVQPGEDLTRTLKLVGDAAAIAKTDMQSMGAIFNKVATSNKVQ
MSMEG_6826|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_1934|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4429|M.thermoresistible__bu GEVMAQLHDRGIPILQLLSEEIGKTAEETAKMASDGKIDFETFRNAIERG
MSMEG_6826|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_1934|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4429|M.thermoresistible__bu MGGAALKAGETFEGAMANMRAALGRLGAEILKGPFESAPAVIGRVTEGID
MSMEG_6826|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_1934|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4429|M.thermoresistible__bu VATDAVKGMVTYLRTGEVTDTFRDVFGRGDMSRRVLAGLERVRTVARQVR
MSMEG_6826|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_1934|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4429|M.thermoresistible__bu DGFEELQAAWRGDDGAADWATKAVDFVRDSLARVWDIAKQLGPALAGIAA
MSMEG_6826|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_1934|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4429|M.thermoresistible__bu SFAKASAAVGVSAWTIFLRTAEALVPILTTIADLITSHQGVVTALVAAYA
MSMEG_6826|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_1934|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4429|M.thermoresistible__bu LLKTGFIGAAVAAKGLAVIKTVTGWMTGLIGVTTAAGTVMSTTLTTVATD
MSMEG_6826|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_1934|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4429|M.thermoresistible__bu ADGLGSSMGGLGERTKKGMRETLRSLKALRGEIGTTMLMAGTAATATSSG
MSMEG_6826|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_1934|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4429|M.thermoresistible__bu IAQTIGALSSVAGGALAGSIFGPAGAAIGAGIGGGIALASYLLGENARAA
MSMEG_6826|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_1934|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4429|M.thermoresistible__bu RAAAAAQAELAQQVQRAKEAQLASLGAQKELNAALLESAGVVDEAAVAAV
MSMEG_6826|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_1934|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4429|M.thermoresistible__bu ARTIDNLPEMLRGRLSDEQVQGVVESIQKLGVSSESLASQLTRGGPALDA
MSMEG_6826|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_1934|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4429|M.thermoresistible__bu TLAALRAMGGPDGERAADALLGVAARFDHARTRAEAAAPALSEMAQKMGV
MSMEG_6826|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_1934|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4429|M.thermoresistible__bu DVLQAADDLSVALKAVPQNIPLNMDMPGAEALVGLLREAGAAVEVLGDGT
MSMEG_6826|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_1934|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4429|M.thermoresistible__bu VHLDVNDERVRDAITVVDSLGWAIKQVPDTKQIEITVKTDEAALQRFISQ
MSMEG_6826|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_1934|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4429|M.thermoresistible__bu MTTEMQKFTTLWITPQLTGEIPAGQPRPNPTAGGNALDPGFFIPGGRADG
MSMEG_6826|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_1934|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4429|M.thermoresistible__bu GVLPGYSPGRDNMLVPLSGGEGIIIPEAMRALGGSWLYQLNSRFRPGISR
MSMEG_6826|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_1934|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4429|M.thermoresistible__bu RGYADGGVHRGSGALPGPVFDTRDDDEPLKLLEDIRDLLAGAGPTTAPLN
MSMEG_6826|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_1934|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4429|M.thermoresistible__bu VTAREVSTLADRAVGRMAGMTPGGTGPFGTPIAPRHRGYEMAAAAISALG
MSMEG_6826|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_1934|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4429|M.thermoresistible__bu GDPEKWLGAEPVSYWRERINESVQAVQQATSAMGPVVSDMGRYVEALQEF
MSMEG_6826|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_1934|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4429|M.thermoresistible__bu ARTGDLSAVQGVGLSATDSVITAITSARNKKTGRLSDTEIGALIEQTLGP
MSMEG_6826|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_1934|M.vanbaalenii_PYR-1 ---MDRSSAEEPGGPPTVVATAEPPAVPQVDDQEKPARELRGWTQRFVAG
TH_4429|M.thermoresistible__bu SGYVGVLDERNASLVKSLQSFRDKVAKGSGTMTGGALVAGLPAHTGAATF
MSMEG_6826|M.smegmatis_MC2_155 -------------------MYQQVLDPVVNSLAWSAAVAAIPLLLLFVLL
Mvan_1934|M.vanbaalenii_PYR-1 VAFG--------VAILTIWQVFRPLSQGSQYYLIVFLAGSLPLVFLAYRS
: ...:*
TH_4429|M.thermoresistible__bu STSGLMPATAALGQAVLQMFPQIREIGGYRQDPHPDHPSGRAIDIMIPGG
MSMEG_6826|M.smegmatis_MC2_155 GVFKMTAWKASLISLAVSIAVAVLVYG---------MPIGQSLLAASEG-
Mvan_1934|M.vanbaalenii_PYR-1 GIRSSRSSQQEPGALDWSLALVTLLVCLYPILPVRIGAGGGGYNAFLDRQ
. . .: . * .
TH_4429|M.thermoresistible__bu TTRGGRNPAGEALGDQIWNWLMSTGIVDPKGSLWKTDVGGDHFDHIHARI
MSMEG_6826|M.smegmatis_MC2_155 ----------AAFGFFPILWIVINAIW-----VYQMTVETGHFDVLRRSF
Mvan_1934|M.vanbaalenii_PYR-1 GMLEPIDVAMGALLLVLILEACRRTTGWALPVVCAMFLAYGYYGGLMPQG
*: : : .::. :
TH_4429|M.thermoresistible__bu AEGMENAAIQAGLIPAAAGTPAASLGGLSATGGATPVFVTNWPGTGGMGM
MSMEG_6826|M.smegmatis_MC2_155 SSISDDQRIQAIIITFSFGALLEALAGFGTPVAVTSVML----------M
Mvan_1934|M.vanbaalenii_PYR-1 WAIAHAGLDFDQIIDALYNSGSGFFGTPLDVAATYIVLFTIYG--AVLEL
. :* .: :. .. *:. :
TH_4429|M.thermoresistible__bu PPGLQPILDAAAQGSGEAASNVLGDVMSAVASLGQEDWAKRDASYATLNK
MSMEG_6826|M.smegmatis_MC2_155 ALGFRPLKAAVLALVANTAPVAFGAMATPIITLG----KVTELDFDTLGA
Mvan_1934|M.vanbaalenii_PYR-1 SGGARFFVDLSVAAFRRSRSAAGRTTVASGFLLG----TVSGSGTATAVS
. * : : .: . . :. ** . *
TH_4429|M.thermoresistible__bu LVRDRNPMALAAALGLDVEDFTRQGGGHGDITANDGPGYDSSGRLYSDTA
MSMEG_6826|M.smegmatis_MC2_155 MVG-RQTPILAVFVPLALVAIVDGRRGMRAVWP-----------------
Mvan_1934|M.vanbaalenii_PYR-1 VGAITWPIMRRAGYTPERAGGVLAAAGVGALLS-----------------
: . . . * : .
TH_4429|M.thermoresistible__bu ALLDRTFTSLNAQLAAMRDQMVSVIEQVSHKLNDAALEPIVKAGVQSALE
MSMEG_6826|M.smegmatis_MC2_155 -------------AAVVCGVVFAVAQYATSNFLSVPLADVVAS-------
Mvan_1934|M.vanbaalenii_PYR-1 -------------PPTLGAAAFIVAEYLEVSYLTVLGWAMIPT-------
..: . * : . . :: :
TH_4429|M.thermoresistible__bu GLKDSVSHAIGTAMGQAAAPPIADAVRQGMASLPIATSGGDSGGNAFSGL
MSMEG_6826|M.smegmatis_MC2_155 ---------------LASAAAVVALVRVWQPANTYTEVAEPAAVTTHTGP
Mvan_1934|M.vanbaalenii_PYR-1 -----------------VLYYLGILLAVEIDARRFGMKPAHQQSESPWKL
: : : :
TH_4429|M.thermoresistible__bu IPGMASGGPVYGGVAGRDSVPALLMPGEHVLTT-DDVARLGGQSGVYAFR
MSMEG_6826|M.smegmatis_MC2_155 PP--------HGRSGGTGGSADLPEPDQNVEDARADVVKAYAPYGIIIGV
Mvan_1934|M.vanbaalenii_PYR-1 LAR-------FGYHFSSLVAIVVLLAAG--MSATRAVVYATALAFVLSFL
. .* . : . : *. . :
TH_4429|M.thermoresistible__bu AALARTGGVRGFATGGAVVNDVVGAEFFGVSQIPIIGLVVNILIRVLLSV
MSMEG_6826|M.smegmatis_MC2_155 FVICQIPAVKSLLDSATFAGNWPGLNVVDVNGDPSS---MTKFTLNLLTT
Mvan_1934|M.vanbaalenii_PYR-1 DRWGRLTPRRLFDALSVGVRGVLPVVAVCAAAGVIT---------AMTTK
: : : .. . . . . : :
TH_4429|M.thermoresistible__bu LGVQIQARDTLLQMTDEFRQFRGDFQAFDASGRLLNDTSALVDRAQSSEE
MSMEG_6826|M.smegmatis_MC2_155 PGTQMLFAGVLTMVALKLSVSR---------------------AARAYWT
Mvan_1934|M.vanbaalenii_PYR-1 TGLGAQFSSVLVGGVDALTDNR--------------------TLMLALTA
* ..* . : * :
TH_4429|M.thermoresistible__bu MAAQERIRILKIVIEALIRYIIEKVIVPIGKAVANAAISAGASAAGAAIN
MSMEG_6826|M.smegmatis_MC2_155 TLHQLRWAILTVMAVLALAFVMN------------------LSGQTITLG
Mvan_1934|M.vanbaalenii_PYR-1 VFAAVALALLGLAIPVTASFVIG----------------WVIIGPALLAL
:* : ::: .
TH_4429|M.thermoresistible__bu TQAPGVGGIVSSLITAAGQAGVDIIADVGTDLALAISETVIAVVAEGLQS
MSMEG_6826|M.smegmatis_MC2_155 TFMAAAGGAFALLSPILGWLGVAVTGSDTSANSLFGALQVTAAYQAGLS-
Mvan_1934|M.vanbaalenii_PYR-1 DVPAPAAAMFVFYYSVLSEVTPPTALAAVGASAVTGGRAIPTMWQALRYA
. ... . . . :: . : :
TH_4429|M.thermoresistible__bu LFPDLMTTIFGGGLLSVLLDPIGNILGNTFGGLLGGITSLLAGLFGGAAT
MSMEG_6826|M.smegmatis_MC2_155 ------------DVLMAASNSSGGVLGKMVSPQNLAIAAAAVGLNGREGD
Mvan_1934|M.vanbaalenii_PYR-1 APAFLVPIAFVLTAPGEYLLGRGPVLGVIWASVAACAGIVALSFAAGGWV
* :** . .: .
TH_4429|M.thermoresistible__bu LIPGLPFDRGGIAYGTGLMPKATIAPERVLSPRQTELFERMVAALERNPR
MSMEG_6826|M.smegmatis_MC2_155 IFR------RVVLWSLGFLVLLCALTALQSSP----VLSWMVPS------
Mvan_1934|M.vanbaalenii_PYR-1 LGVGALAPVPRAFTAIAALLLLFLQPATIAAGSACLLGAVAFTFITDKRR
: . . : . : : ..
TH_4429|M.thermoresistible__bu AATGSTTIVDVGGITVAGGPEAGERVRAGLMELMH
MSMEG_6826|M.smegmatis_MC2_155 -----------------------------------
Mvan_1934|M.vanbaalenii_PYR-1 RT---------------------------------