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KSTLDKTKSRWTRPERRPKGTTTPDAPARPVVTRADPVAAAPEPTPPTTRDGHRQSLTAIVREAHRPERR LTLAPRTAHAVAATPAAPPSDEAPLAPVASTAAVQTTPTPPQPLSPAAQLRALPGRVVNAVLDVLDFTSS ANSPTLPVSLAPVNDLIFGTFREIERLMGLHDTPPEQPVVPAMVYDGPTDRPTPTVAQFLNASTAAYVLG ATPGGLKPFVVDGEQMQSTDIVSGMVGKAWVTPEGQIIIAYQGTTGGSHLLFNPIIVIPQVIADLQVVFT GTTPLAFHDALDFAQQVRAEAARQGYSDDDIFVTGHSLGGWEAQYVAQQTGLAGIGFEAPGINTTVPGNG ADSMFVNIGTYGSSAPYMATDLPGLQPFMPPYVPGGGSKPHYGPIVMIGDPAAMTPLYNASTLWGTSVTG SVIFLVDYLMNFFQYHLPGVQAYHLDVTPDPGVVPFLGTARGPVHEGYGELTIPELLARASDDGILFQP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_6781 | - | - | 100% (490) | hypothetical protein MSMEG_6781 |
| M. smegmatis MC2 155 | MSMEG_6285 | - | 3e-05 | 33.03% (109) | DNA polymerase III subunits gamma and tau |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_3843 | - | 2e-06 | 28.91% (211) | hypothetical protein Mflv_3843 |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_3358 | - | 5e-07 | 35.00% (120) | hypothetical protein MMAR_3358 |
| M. avium 104 | - | - | - | - | - |
| M. thermoresistible (build 8) | TH_2337 | - | 0.0 | 70.24% (494) | hypothetical protein MSMEG_6781 |
| M. ulcerans Agy99 | MUL_1237 | - | 4e-05 | 35.25% (122) | transmembrane ATP-binding protein ABC transporter |
| M. vanbaalenii PYR-1 | Mvan_0447 | - | 1e-171 | 69.25% (426) | hypothetical protein Mvan_0447 |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_6781|M.smegmatis_MC2_155 --------------------------------------------------
TH_2337|M.thermoresistible__bu --------------------------------------------------
Mvan_0447|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3843|M.gilvum_PYR-GCK MSRTKKSIVVVMMGSAGLFLSAPLLGPAANATPTRGGVPCVGILQQIVTR
MMAR_3358|M.marinum_M --------------------------------------------------
MUL_1237|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_6781|M.smegmatis_MC2_155 --------------------------------------------------
TH_2337|M.thermoresistible__bu --------------------------------------------------
Mvan_0447|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3843|M.gilvum_PYR-GCK PGEIPQALTDTARSFTEPPKPAPPVVRPPASSSSSAGTPPVPGRPPASVV
MMAR_3358|M.marinum_M --------------------------------------------------
MUL_1237|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_6781|M.smegmatis_MC2_155 --------------------------------------------------
TH_2337|M.thermoresistible__bu --------------------------------------------------
Mvan_0447|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3843|M.gilvum_PYR-GCK TPSSGATPPVPPSPGTPASTSTRGGTPPVPPAPPAPAGTPASGATPPAPP
MMAR_3358|M.marinum_M --------------------------------------------------
MUL_1237|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_6781|M.smegmatis_MC2_155 --------------------------------------------------
TH_2337|M.thermoresistible__bu --------------------------------------------------
Mvan_0447|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3843|M.gilvum_PYR-GCK VPGVPAVTSTGGGTPPVPPVPGAPVGAPVANPGLPTPPVPGAPVFGDGGA
MMAR_3358|M.marinum_M --------------------------------------------------
MUL_1237|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_6781|M.smegmatis_MC2_155 --------------------------------------------------
TH_2337|M.thermoresistible__bu --------------------------------------------------
Mvan_0447|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3843|M.gilvum_PYR-GCK VLPPLPPAPAGPAGGPAGLVAPPAPPVPGGPAAVPAGVALPPAPPGAPGA
MMAR_3358|M.marinum_M --------------------------------------------------
MUL_1237|M.ulcerans_Agy99 ----------MWLGSMRYVFAPGRDALVGYGNKFDIRLDGPAPFDTFDRP
MSMEG_6781|M.smegmatis_MC2_155 --------------------------------------------------
TH_2337|M.thermoresistible__bu --------------------------------------------------
Mvan_0447|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3843|M.gilvum_PYR-GCK PVFGEAGAAPSGAAAPVAPAAGSGGAGGAGGGSGIGGPGGGGAPVEGTGG
MMAR_3358|M.marinum_M ---------------------------------------------MAEGA
MUL_1237|M.ulcerans_Agy99 TPELALRFAGNRWVAIDQSRNGMFVDGARLATVDIRDGLTITVGDPHHGT
MSMEG_6781|M.smegmatis_MC2_155 --------------------------MKSTLDKTKSRWTRPERRP-----
TH_2337|M.thermoresistible__bu -VTEEPGLAGSSR--RAVSGFAPGPVVGRWSERADTPLTRLRDRD-----
Mvan_0447|M.vanbaalenii_PYR-1 --MEEVDLRESRRRIRSLTYGVAAATIAAVVAAVPVQGTAWADSPT----
Mflv_3843|M.gilvum_PYR-GCK AVPAGAPLAAAGGEVPPPAPPIPGAPVIGEAGVVPPPAPPAPAPPAGGLG
MMAR_3358|M.marinum_M RPALGLSIGATNLAAVTADSAILRKPVLTLYRQRPPEIGLPSENPR----
MUL_1237|M.ulcerans_Agy99 PLRFQVTAAAGARSLPADPPRGPGHPAPRPARAEPAPPQPVPPSKP----
MSMEG_6781|M.smegmatis_MC2_155 ------------------KGTTTPDAPARPVVTR-ADPVAAAP-------
TH_2337|M.thermoresistible__bu ------------------RLRTVATKPAEPVDNTGPEPGAAET-------
Mvan_0447|M.vanbaalenii_PYR-1 --------------VESTSSTTVDAAPAAPDTATEADTGEQAQPDVGAEE
Mflv_3843|M.gilvum_PYR-GCK GAVPPPVPGAPGVPVVDEAGVVTPPAPGGPGVPTGGEGGVVTPPAPG--A
MMAR_3358|M.marinum_M ---------------LDQSGLVISDFVDRVGDQIGIVAADGSVHR-----
MUL_1237|M.ulcerans_Agy99 ------------------TESVTQQLPTASATQRIATPPPAPSTFER---
.
MSMEG_6781|M.smegmatis_MC2_155 ------------------EPTPPTTR-------DGHRQ------------
TH_2337|M.thermoresistible__bu ------------------DPHRSPTRSAAAAPQPSSRP------------
Mvan_0447|M.vanbaalenii_PYR-1 PAESEVDTEGPADPDDPEEPAAPEPEDTEDVEEPGAVPG------EAEGG
Mflv_3843|M.gilvum_PYR-GCK PGVPVVDEAGVVTPPAPGGPGVPTGGEGGVVTPPAPGAPGAPVVDEAGVV
MMAR_3358|M.marinum_M -------------------SEALVADALRALAYTATGG------------
MUL_1237|M.ulcerans_Agy99 ----------ATRPIRLAPLGAPAAPPPMPPHPPAPPSP-----------
.
MSMEG_6781|M.smegmatis_MC2_155 ----------SLTAIVR-------------------EAHRPERRLTLAPR
TH_2337|M.thermoresistible__bu ----------VVVTLVEPID-----------LPDVTTPAPPVRKRALAPG
Mvan_0447|M.vanbaalenii_PYR-1 GDPRPVQPDETEVVAVEPFSDDSDAEPDAEFSRDVVTTGPAERTGAAVAT
Mflv_3843|M.gilvum_PYR-GCK TPPAPGGPGVPAVGDTAVVTPPAPGAPGTPAVNSVETFSPPAPPAATPPS
MMAR_3358|M.marinum_M ---------HTLPASTAVAYP---------------AHWTTSAVDALGAA
MUL_1237|M.ulcerans_Agy99 ----------PRPPSQSSPTPPTPELPAASAPAASEGEEQPKSRGLVERM
.
MSMEG_6781|M.smegmatis_MC2_155 TAHAVAATPAAPPSD-------------EAP---LAPVASTAAVQTTPTP
TH_2337|M.thermoresistible__bu -AHPDALVPRAVLGS-------------DTS---DEPEVSEPSEAPGPTA
Mvan_0447|M.vanbaalenii_PYR-1 LTPAAQLLTIEVPDT-------------EAPALVPAPVITTTTIEAPPSA
Mflv_3843|M.gilvum_PYR-GCK SGSVETFSPPAPPAPGTGTNSTVEISTPPPPGTPGLPSEGSTTYTTPPTP
MMAR_3358|M.marinum_M LGRVPEWSPAGQPLL-------------------LIPDAAAALFAARANP
MUL_1237|M.ulcerans_Agy99 IDATRKLLPDRAETDS-----------ASASDSDSDSGSSTGTGELPSTN
. . ..
MSMEG_6781|M.smegmatis_MC2_155 PQPLSPAAQLRALPGR-----VVNAVLDVLDFTSSANSPTLP--------
TH_2337|M.thermoresistible__bu PQPLSPVAELLELPAR-----IVNTVLEALDLTSSADTPTLP--------
Mvan_0447|M.vanbaalenii_PYR-1 PKPLSPLAKLLQLPGR-----LINAFLQVFDLTSSASTPRSP--------
Mflv_3843|M.gilvum_PYR-GCK EITLNPANSGIDIATPPA-PGLPGAPLEATANITTPGTPGVPGAPVNSSI
MMAR_3358|M.marinum_M GIPARGVVAVCDFGGSGTSITLADASGEYQPLGATVRHPDFS--------
MUL_1237|M.ulcerans_Agy99 RLPLKPGARTIGVAAY-----QLGLTVDGHELISDVSFTTRP--------
. . . : : . .
MSMEG_6781|M.smegmatis_MC2_155 ---------VSLAPVNDLIFGTFREIERLMGLHD-------TPPEQ----
TH_2337|M.thermoresistible__bu ---------VSLAPVNDLIFGTYREIERLLGLWE-------TPPPQ----
Mvan_0447|M.vanbaalenii_PYR-1 ---------LSLGPINDLLFAAFREFERLLGLDQ-------PPAVQ----
Mflv_3843|M.gilvum_PYR-GCK DVATPGEVGVPAAPIERSMTVTTPDTPGAPGAPANAAVDVATPPAPGVPG
MMAR_3358|M.marinum_M -----------GDLIDQSLLTYVMSEMPATGSFD--------P-------
MUL_1237|M.ulcerans_Agy99 ------------GSLIAVVGPSRARNSSLAGLLAR------TRPLS----
: : *
MSMEG_6781|M.smegmatis_MC2_155 --------------------------------------------------
TH_2337|M.thermoresistible__bu --------------------------------------------------
Mvan_0447|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3843|M.gilvum_PYR-GCK APVVGEAGVTTPGAPGAPGAPANAAVDVATPPAPGVPGAPVVGEAAVTTP
MMAR_3358|M.marinum_M --------------------------------------------------
MUL_1237|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_6781|M.smegmatis_MC2_155 -----PVVPAMVYDGPTDRPTPTVAQFLNASTAAYVLGATP---------
TH_2337|M.thermoresistible__bu -----PAVPTMTYTGPIDQPTPTVAQFLNASTAAYVLGSTP---------
Mvan_0447|M.vanbaalenii_PYR-1 -----PEVPALTYDGPTTATTPTVAQFLNASAAGYVLGGAP---------
Mflv_3843|M.gilvum_PYR-GCK GAPGVPGVPAGGDAGVVTPPAPGVPGAPVVGEAGVTTPGAPGVPGVPAGG
MMAR_3358|M.marinum_M -----SGTSAIGSLNRLRAECRQAKEQLSLSTVATLSDALPG--------
MUL_1237|M.ulcerans_Agy99 -----DGVLTVDGHDVAAEPESMRSRIGVVTRDNRVHPRLTVEQALS---
. : . .
MSMEG_6781|M.smegmatis_MC2_155 -GGLKPFVVDGEQMQSTDIVSGMVGKAWVTPEGQIIIAYQGTTG------
TH_2337|M.thermoresistible__bu -GDLVPFTVNGFQMSRTNLMTGTVAKTWVTPEGQIIIAYQGTTG------
Mvan_0447|M.vanbaalenii_PYR-1 -ADLVPFTVNGFQMSSTNIFSGMVAKTWVTPQGQIIIAYQGTTG------
Mflv_3843|M.gilvum_PYR-GCK DAGVVTPPAPGVPGAPAATEAGLATPPGPGAPGAPVVGDAGVATPPGPGV
MMAR_3358|M.marinum_M VSGEVRLTRNELDETIRDSLDGFARVVEHTLQRAGVPAAD----------
MUL_1237|M.ulcerans_Agy99 YAARMRLPPDTSADNRRRVVNQVLDEVELTAQRATRVAKLTPDERR-CAA
. .
MSMEG_6781|M.smegmatis_MC2_155 -GSHLLFNP-IIVIPQVIADLQVVFTGTTPLAFHDALDFAQQVRAEAARQ
TH_2337|M.thermoresistible__bu -GSHLLFNP-LIVIPQVIADLQVVFTGTTPAAFHDALDFAEQVRAEAVRQ
Mvan_0447|M.vanbaalenii_PYR-1 -GSNLLFNP-LITVSQVLADLQVIFTRTTPWAFHDALYFAKRVQIRAAEQ
Mflv_3843|M.gilvum_PYR-GCK PGAPIVDEAGLATPPAPVAPVEGAGGAVPPAGPPPAPVFGDAGAPVEAAA
MMAR_3358|M.marinum_M -LVAIVTVGGGANIPSVTTTLSGRFGVPVITAPRPQLTAATGGALRAARG
MUL_1237|M.ulcerans_Agy99 MAIELITRPSLLVVDEPSAGLNPAQEMHVLAMLRRQADLGCVVVVASMPL
:: : :. .
MSMEG_6781|M.smegmatis_MC2_155 G--YSDDDIFVTG--------------HSLGGWEAQYVAQQTGLAG---I
TH_2337|M.thermoresistible__bu G--YSEDDIFVTG--------------HSLGGWQAQFVAQQTGMAG---V
Mvan_0447|M.vanbaalenii_PYR-1 G--YSSENIFVTG--------------HSLGGWEAQYVAQQIGLAG---I
Mflv_3843|M.gilvum_PYR-GCK GGAPVEAAAGVTGGGSVAGAGAGGGAGGAAGGAGVEGASGAVGAAGGPGA
MMAR_3358|M.marinum_M PGDSSATVLTSAAP------------MTQTAMAPLDPDVGAVAAADAPVS
MUL_1237|M.ulcerans_Agy99 AHLNMCDQVLLLTP------------AGTLAFAGPPVQIESTMGTASWPD
. :
MSMEG_6781|M.smegmatis_MC2_155 GFEAPGINTTVPGNGADSMFVNIGTYGSSAPYMATDLP-----GLQPFMP
TH_2337|M.thermoresistible__bu GFEAPGINTTVPGNGADSMFVNIGTYGSSAPYLATDLP-----GLQPFMP
Mvan_0447|M.vanbaalenii_PYR-1 GFEAPGINTRVPGNGADAMFVNVGTYGSAAPYMSTDLP-----GLQPFMP
Mflv_3843|M.gilvum_PYR-GCK GAAPAAAGGAAPGGAPGGPVAGGGPVGGPGALPAPGAPIVGEAGVVSPPA
MMAR_3358|M.marinum_M ALQPALAWSEADDQSRAMPVVGDDYSGASGYTSARPQLTFEENARAEPAP
MUL_1237|M.ulcerans_Agy99 IFARVSADPQAAHQSFQNRLRASVSPTPPSVLEPERRPAELTFGAQVRLI
. . . .. . .
MSMEG_6781|M.smegmatis_MC2_155 P-----YVPGGGSKPHYGPIVMIGDPAAMTPLYNASTLWGTSVTGS-VIF
TH_2337|M.thermoresistible__bu P-----FVPGGGAKPHYGPIVMVGDPAAMTPLYNASALWGRSITGS-AVF
Mvan_0447|M.vanbaalenii_PYR-1 P-----YVPGGGSKPHYGPIVMIGDPAAITPLRNASALWGKSLIGS-VIF
Mflv_3843|M.gilvum_PYR-GCK P-----GVPGGAAAVPAGAVTPPAPGVPGAPVFGEAGVVTPPAPGV-PGG
MMAR_3358|M.marinum_M K-----SVVIPWYRLPGVIIVATVVAVLLVGAAVAIALSSGEQPATRSPE
MUL_1237|M.ulcerans_Agy99 LRRQVRVFLASRLYFVFLTLLPFALDALTLLIPGDAGLDRPPPGSGNPHE
. : . : .
MSMEG_6781|M.smegmatis_MC2_155 LVDYLMNFFQYHLPGVQAYHLDVTPDPGVVPFLGTARGPVHEGYGELT--
TH_2337|M.thermoresistible__bu LAAFLMNFFQYHLPGVQAYHLDVTPDPGVVPFLGTARGPVHAGYGELT--
Mvan_0447|M.vanbaalenii_PYR-1 LVDFLGNFFQYHLPGVQAHHLDVVPDPGMVPWMGRPSGPVHTGWGALS--
Mflv_3843|M.gilvum_PYR-GCK AAAVPAGVVTPPAPGVPGGAAAVPAGAVTPPAPGVPGAPVFGDAGVATPP
MMAR_3358|M.marinum_M ATTSPPTSAPAAVPPVTDAGTSAPAPSTQPPASQEPAPPPTQQAPPPP--
MUL_1237|M.ulcerans_Agy99 AVEILAALNFAAVLMGTALTVRDLVSERQIFRREQAVGLSASTYLIGKII
. .
MSMEG_6781|M.smegmatis_MC2_155 --------------------------------------IPELLARASDDG
TH_2337|M.thermoresistible__bu --------------------------------------IPQLLAAASEDG
Mvan_0447|M.vanbaalenii_PYR-1 --------------------------------------IQGLMKAASDAG
Mflv_3843|M.gilvum_PYR-GCK VPGVPGGGTTVPAASVTPPAPGVPGGASTVPGNAGTPSTPGLPPGSTDTY
MMAR_3358|M.marinum_M -------------------------------------STEAPPPSTTQAP
MUL_1237|M.ulcerans_Agy99 MFG----------------------------------LVAAVQAAILTAI
MSMEG_6781|M.smegmatis_MC2_155 ILFQP---------------------------------------------
TH_2337|M.thermoresistible__bu ILFQP---------------------------------------------
Mvan_0447|M.vanbaalenii_PYR-1 QLFRP---------------------------------------------
Mflv_3843|M.gilvum_PYR-GCK INYPAPPVPPTPPNSTGVSAGTPGSPAPGTPGSTLTLTDLLTPPGIARTL
MMAR_3358|M.marinum_M VTTQPPATTEAPPATTQPPVTTEAPPTTQAPATQQLPTPPPIPP------
MUL_1237|M.ulcerans_Agy99 VLLIKGQPVHGTALLPNPGVEIYASVAATTIVSAIIGLTLSTLGSSLREV
MSMEG_6781|M.smegmatis_MC2_155 --------------------------------------------------
TH_2337|M.thermoresistible__bu --------------------------------------------------
Mvan_0447|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3843|M.gilvum_PYR-GCK QNTASSVMGATPPGTPPVPGGSGSVSLAVPGTPSPIAPLAATGLSNLVSP
MMAR_3358|M.marinum_M -----------IPQIPPIPQIPGIGFPQVPQVP-----------------
MUL_1237|M.ulcerans_Agy99 LPLVVPVILASLLFAGGLVPLVGTWGFDQIAWFVPAHWGFAATASTVNLH
MSMEG_6781|M.smegmatis_MC2_155 --------------------------------------------------
TH_2337|M.thermoresistible__bu --------------------------------------------------
Mvan_0447|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3843|M.gilvum_PYR-GCK PSLTIPSIPGLPVPLPNTVPVPSDLLCVGTDWSASQGDSAATPPAAEVPR
MMAR_3358|M.marinum_M QIPQVPQVPGVP------------------------GFGQVIAPQVIAPQ
MUL_1237|M.ulcerans_Agy99 RVDVLATHNEVWAHYAGWWAFDIGMLVTFGVVAAGLARYRLRPPGVPADH
MSMEG_6781|M.smegmatis_MC2_155 ------------------
TH_2337|M.thermoresistible__bu ------------------
Mvan_0447|M.vanbaalenii_PYR-1 ------------------
Mflv_3843|M.gilvum_PYR-GCK VVTGAAPTGDRRDRWGNR
MMAR_3358|M.marinum_M VIAPQAANGQ--------
MUL_1237|M.ulcerans_Agy99 GIAHSRS-----------