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TIAYDDALRERIRTHLAGHDRRVTTDPTKRHAAVAVVLVDSELGEDRVDPAPVEDWIGGRPVLEAGLDGR MVDVSGGAAFLMCRRATRLTSHSAQWALPGGRVDPGETVEEAALRELDEELGVRLPESTVLGLLDDYPTR SGYVITPVVIWGGGRLELSPSPDEVVAAYRVGLHQLQREDSPRFVAIPESPRPVVQIPLGNDLIHAPTGA VLLQVRRLCLEGRPDPVYDLEQPVFAWK*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_6617 | - | - | 100% (239) | nudix hydrolase |
| M. smegmatis MC2 155 | MSMEG_6185 | - | 7e-06 | 38.89% (90) | NTP pyrophosphohydrolase |
| M. smegmatis MC2 155 | MSMEG_0790 | - | 7e-06 | 41.82% (55) | hydrolase, NUDIX family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3938 | - | 4e-05 | 45.00% (40) | hypothetical protein Mb3938 |
| M. gilvum PYR-GCK | Mflv_1043 | - | 1e-111 | 80.33% (239) | NUDIX hydrolase |
| M. tuberculosis H37Rv | Rv3908 | - | 4e-05 | 45.00% (40) | hypothetical protein Rv3908 |
| M. leprae Br4923 | MLBr_02698 | - | 9e-06 | 45.00% (40) | hypothetical protein MLBr_02698 |
| M. abscessus ATCC 19977 | MAB_4210 | - | 1e-113 | 82.28% (237) | putative MutT/NUDIX family protein |
| M. marinum M | MMAR_0135 | - | 1e-117 | 83.68% (239) | hypothetical protein MMAR_0135 |
| M. avium 104 | MAV_1301 | - | 8e-07 | 46.30% (54) | hydrolase, NUDIX family protein |
| M. thermoresistible (build 8) | TH_1236 | - | 1e-113 | 82.85% (239) | nudix hydrolase |
| M. ulcerans Agy99 | MUL_4962 | - | 1e-114 | 82.43% (239) | hypothetical protein MUL_4962 |
| M. vanbaalenii PYR-1 | Mvan_5787 | - | 1e-110 | 80.33% (239) | NUDIX hydrolase |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_6617|M.smegmatis_MC2_155 -------MTIAYDDALRERIRTHLAGHDRRVTTDPTKRHAAVAVVLVDSE
MAB_4210|M.abscessus_ATCC_1997 --------MIAYDEELRNRIRAHLARHERRTVDDPAKRRAAVAVVLVDSD
MMAR_0135|M.marinum_M -------MTITYDEALRLRIRARLTSHERRAVTDPTKRHAAVAVVLVDSE
MUL_4962|M.ulcerans_Agy99 -------MTITYDEALRLRIRARLTSHERRAVTDPTKRHAAVAVVLVDSE
Mflv_1043|M.gilvum_PYR-GCK -------MTLGYDDVLRDRIAQRLGQHTRRTVTDPSKRHAAVAVVLVDSV
Mvan_5787|M.vanbaalenii_PYR-1 -------MTITYDDRLRDQLQQRLAGHARRTVSDPSKRHAAVAVVLVDSL
TH_1236|M.thermoresistible__bu ---MVEQVTIPYDAELRESIRRNLAGHDRRVVTDPTKRHAAVAIVLVDSE
Mb3938|M.bovis_AF2122/97 -------MSDGEQAKSRRRRGRRRGRRAAATAENHMDAQPAGDATPTPAT
Rv3908|M.tuberculosis_H37Rv -------MSDGEQAKSRRRRGRRRGRRAAATAENHMDAQPAGDATPTPAT
MLBr_02698|M.leprae_Br4923 MPAIIAWVSDGEQAKPRRRRKRRRGRDATRSAENHTDRQVANDATAT---
MAV_1301|M.avium_104 --------------------------------------------------
MSMEG_6617|M.smegmatis_MC2_155 LGEDRVDPAPVEDWIGGRPVLEAGLDGRMVD-VSGGAAFLMCRRATRLTS
MAB_4210|M.abscessus_ATCC_1997 LGEDRIDPAPLEEWIGGREIPGHGLDGRMVD-VSGGAAFLLCRRASRLNS
MMAR_0135|M.marinum_M VGEDRVDPAPVDEWIGGRPMPEPGLDGRMVD-VSGGAAFFLCRRASRLRA
MUL_4962|M.ulcerans_Agy99 VGEDRVDPAPVDEWIGGRLMPEPGLDGRMVD-VSGGAAFFLCRRASRLRA
Mflv_1043|M.gilvum_PYR-GCK VGEDRVDPAPVDDWIAGRPMPD-DLDGRMVD-VSGGAAFLLCRRASRLSS
Mvan_5787|M.vanbaalenii_PYR-1 AGEDRVDPAPVDDWIAGRPMPE-DLDGRMVD-VSGGAAFFLCRRASRLSS
TH_1236|M.thermoresistible__bu VGEDRVDPAPVDDWNAGRGLSAPDLDGRMVD-VSGGAAFVLCRRAFRLSS
Mb3938|M.bovis_AF2122/97 AKRSRSR-SPRRGSTRMRTVHETSAGGLVIDGIDGPRDAQVAALIGRVDR
Rv3908|M.tuberculosis_H37Rv AKRSRSR-SPRRGSTRMRTVHETSAGGLVIDGIDGPRDAQVAALIGRVDR
MLBr_02698|M.leprae_Br4923 -KPRRSH-SPHRAPEQLRTVHETSAGGLVIYGIDGPRDAQVAALIGRIDR
MAV_1301|M.avium_104 --------MRADGIPSLAMPTQIVVAGALIR----GSRLLVAQRARPPEL
* :: :.
MSMEG_6617|M.smegmatis_MC2_155 HS-AQWALPGGRVDPGETVEEAALRELDEELGVRLPESTVLGLLDDYPTR
MAB_4210|M.abscessus_ATCC_1997 HA-AQWALPGGRLDPGEDAIQAALRELDEELGVSLPDSTVLGLLDDYPTR
MMAR_0135|M.marinum_M HA-AQWALPGGRVDPGETAIEAALRELDEEIGIRLPDSAVLGLLDDYPTR
MUL_4962|M.ulcerans_Agy99 HA-AQWALPGGRVDPGENAIEAALRELDEEIGIRLPDSAVLGLLDDYPTR
Mflv_1043|M.gilvum_PYR-GCK HS-AQWALPGGRLDPGETVVEAALRELDEEVGVRLPESALLGLLDDYSTR
Mvan_5787|M.vanbaalenii_PYR-1 HS-AQWALPGGRLDPGETVVDAALRELDEEVGVRLTETSVLGLLDDYPTR
TH_1236|M.thermoresistible__bu HS-AQWALPGGRVDPGETIVEAALRETHEEVGVTLPESSVLGLLDDYPTR
Mb3938|M.bovis_AF2122/97 RGRLLWSLPKGHIELGETAEQTAIREVAEETGIRGSVLAALGRIDYWFVT
Rv3908|M.tuberculosis_H37Rv RGRLLWSLPKGHIELGETAEQTAIREVAEETGIRGSVLAALGRIDYWFVT
MLBr_02698|M.leprae_Br4923 RGRMLWSLPKGHIEQGETAEQTAIREVAEETGIRGSVLAALGQIDYWFVT
MAV_1301|M.avium_104 AG--RWELPGGKVAPGETERDALARELAEELGLRVGDIAVGDRLGGDIAV
. * ** *:: ** :: ** ** *: : . :. .
MSMEG_6617|M.smegmatis_MC2_155 SGYVITPVVIWGGGRLELSPSPD---EVVAAYRVGLHQLQR----EDSPR
MAB_4210|M.abscessus_ATCC_1997 SGYVITPVVVWGGGRLELSPSPD---EVVAAYRVGLHQLQR----EDSPR
MMAR_0135|M.marinum_M SGYVITPVVIWGGGRLDPHPVPD---EVVAVYRVGLHQLQR----QDSPR
MUL_4962|M.ulcerans_Agy99 SGYVITPVVIWGGGRLDPHLVPD---EVVAVYRVGLHQLQR----QDSPR
Mflv_1043|M.gilvum_PYR-GCK SGYVITPVVLWGGGRLDPRPAPD---EVVAVYRVGLHQLLR----EDSPR
Mvan_5787|M.vanbaalenii_PYR-1 SGYVITPVVIWGGGRLDPRPAPD---EVVAVYRVGLHQLLR----EDSPR
TH_1236|M.thermoresistible__bu SGYVITPVVIWGGGRLDLRPAPD---EVVAAYRVGLHQLQR----PDSPR
Mb3938|M.bovis_AF2122/97 DGRRVHKTVHHYLMRFLGGELSDEDLEVAEVAWVPIRELPSRLAYADERR
Rv3908|M.tuberculosis_H37Rv DGRRVHKTVHHYLMRFLGGELSDEDLEVAEVAWVPIRELPSRLAYADERR
MLBr_02698|M.leprae_Br4923 DDCRVHKTVHHYLMRFSGGELSDDDLEVTEVAWVPIRELPSRLAYADERR
MAV_1301|M.avium_104 DGG--MTLRAYRVRLLRGRPDAR---DHRALRWITAAQLHD---------
.. : . : : :*
MSMEG_6617|M.smegmatis_MC2_155 FVAIPESPRPVVQIPLGNDLIHAPTGAVLLQVRRLCLEGRPDPVYDLEQP
MAB_4210|M.abscessus_ATCC_1997 YITIPESARPVVQIPLGNDLIHAPTGAVLLQVRWLCLEGSGDRVDDLEQP
MMAR_0135|M.marinum_M FVAIPESPRPVVQVPLGNDLIHAPTGAVLLQVRWLCLEGRDDPVDELEQP
MUL_4962|M.ulcerans_Agy99 FVAIPESPRPVVQVPLGNDLIHAPTGAVLLQVRWLCLEGRDDPVDELEQP
Mflv_1043|M.gilvum_PYR-GCK FITIPESPRPVVQVPLGNDLIHAPTGAVLLQLRWLCLEGRDDPVNELEQP
Mvan_5787|M.vanbaalenii_PYR-1 FITIPESPRPVVQMPLGNDLIHAPTGAVLLQLRWLGLEGRSDPVDELEQP
TH_1236|M.thermoresistible__bu FVSIPESDRPVVQIPLGGDLIHAPTGAVLLQLRLLGLEGRPDPVHDLEQP
Mb3938|M.bovis_AF2122/97 LAEVADELIDKLQSDGPAALPPLPPSSPRRRPQTHSRARHADDSAPGQHN
Rv3908|M.tuberculosis_H37Rv LAEVADELIDKLQSDGPAALPPLPPSSPRRRPQTHSRARHADDSAPGQHN
MLBr_02698|M.leprae_Br4923 LAEVAYELINKLQTGGPAALPPLPPSLPRRQSQTHFRTRHSNNSANSRKN
MAV_1301|M.avium_104 -----------------LDWVPADRGWLGDLARVL---------------
. :
MSMEG_6617|M.smegmatis_MC2_155 VFAWK-
MAB_4210|M.abscessus_ATCC_1997 VFAWR-
MMAR_0135|M.marinum_M VFAWK-
MUL_4962|M.ulcerans_Agy99 VFAWK-
Mflv_1043|M.gilvum_PYR-GCK VFAWR-
Mvan_5787|M.vanbaalenii_PYR-1 VFAWK-
TH_1236|M.thermoresistible__bu VFAWR-
Mb3938|M.bovis_AF2122/97 GPGPGP
Rv3908|M.tuberculosis_H37Rv GPGPGP
MLBr_02698|M.leprae_Br4923 GHGQGP
MAV_1301|M.avium_104 ------