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PRIAYLGPEGTFTEAALLQMVAKGMVPGPAEDAGGFTPVRTDSTPGALSAVREGRADYACVPIENSIDGT VLPTLDSLAAGSPLQIYAELTLDVAFTIVVRPGHDGPVRTVAAFPVAAAQVRHWLAANLRDAEVVPAHSN AAAAHDVAEGRADAGVSTRLAAERCGLDIMAADVVDEPNARTRFVLVGLPGTPPPATGADRTAVVLRLVN EPGALVSAMTEFSIRDIDLTRIESRPTRTELGTYMFFLDCAGHIDDDPVAEALKALHRRCVDVRYLGSWP TESAAGAPPPRLDEATTWLEGLRAGSGGA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_6418 | - | - | 100% (310) | prephenate dehydratase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3868c | pheA | 1e-115 | 69.71% (307) | prephenate dehydratase |
| M. gilvum PYR-GCK | Mflv_1145 | - | 1e-122 | 71.99% (307) | prephenate dehydratase |
| M. tuberculosis H37Rv | Rv3838c | pheA | 1e-115 | 69.71% (307) | prephenate dehydratase |
| M. leprae Br4923 | MLBr_00078 | pheA | 1e-112 | 67.96% (309) | prephenate dehydratase |
| M. abscessus ATCC 19977 | MAB_0132 | - | 1e-105 | 65.05% (309) | prephenate dehydratase |
| M. marinum M | MMAR_5390 | pheA | 1e-113 | 67.10% (307) | prephenate dehydratase PheA |
| M. avium 104 | MAV_0188 | - | 1e-116 | 69.71% (307) | prephenate dehydratase |
| M. thermoresistible (build 8) | TH_1472 | pheA | 1e-123 | 72.44% (312) | POSSIBLE PREPHENATE DEHYDRATASE PHEA |
| M. ulcerans Agy99 | MUL_5011 | pheA | 1e-113 | 66.78% (307) | prephenate dehydratase |
| M. vanbaalenii PYR-1 | Mvan_5662 | - | 1e-125 | 73.55% (310) | prephenate dehydratase |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_6418|M.smegmatis_MC2_155 --MPRIAYLGPEGTFTEAALLQMVAKGMVP-----GPAEDAGGFTPVRTD
TH_1472|M.thermoresistible__bu --MPRIAYLGPEGTFSESALLQMSARGMVPRAVPKDASGDPNGMTAVSVE
Mflv_1145|M.gilvum_PYR-GCK --MPGIAYLGPEGTFTEAALRALDAQGLIPATQ-----SGAGSVTPLATD
Mvan_5662|M.vanbaalenii_PYR-1 --MPGIAYLGPEGTFTEAALRALQAHGLIPSTAP--DAAGADEVTPIAAD
MAB_0132|M.abscessus_ATCC_1997 --MQRITYLGPEGTFSEAAMITLRTTGRIPGSS---------EVEPVSVA
Mb3868c|M.bovis_AF2122/97 --MVRIAYLGPEGTFTEAALVRMVAAGLVPETG-------PDALQRMPVE
Rv3838c|M.tuberculosis_H37Rv --MVRIAYLGPEGTFTEAALVRMVAAGLVPETG-------PDALQRMPVE
MLBr_00078|M.leprae_Br4923 MSVARIAYLGPEGTFTEAALLRMTAAGLVPDTG-------PDGLRRWPTE
MAV_0188|M.avium_104 --MARIAYLGPEGTFTEAALRQITAAGLVPGQG-------ADGVRPTPVD
MMAR_5390|M.marinum_M --MARIAYLGPEGTFTQAALLEIAAAGLVPGHD-------DGGAQPLPVE
MUL_5011|M.ulcerans_Agy99 --MARIAYLGPEGTFTQAALLEIAAAGLVPGHD-------DGGAQPLPVD
: *:********:::*: : : * :* .
MSMEG_6418|M.smegmatis_MC2_155 STPGALSAVREGRADYACVPIENSIDGTVLPTLDSLAAGSPLQIYAELTL
TH_1472|M.thermoresistible__bu STPAALAAVRSHDADYACVPIENSIEGSVLPTLDNLAVGNPLQIFAELTL
Mflv_1145|M.gilvum_PYR-GCK STPAALAAVRAGDADFACVPIENSIDGPVIPTLDSLADGVPLQIYAELTL
Mvan_5662|M.vanbaalenii_PYR-1 STSAALAAVRSGDADFACVPIENSIDGSVIPTLDSLADGAALQIYAELTL
MAB_0132|M.abscessus_ATCC_1997 SAREALVQVQAGDADYACVPIESSLEGPVVPTLDTLAVGAPLQIFAETVL
Mb3868c|M.bovis_AF2122/97 SAPAALAAVRDGGADYACVPIENSIDGSVLPTLDSLAIGVRLQVFAETTL
Rv3838c|M.tuberculosis_H37Rv SAPAALAAVRDGGADYACVPIENSIDGSVLPTLDSLAIGVRLQVFAETTL
MLBr_00078|M.leprae_Br4923 STPAALDAVRGGAADYACVPIENSIDGSVAPTLDNLAIGSPLQVFAETTL
MAV_0188|M.avium_104 GTPAALDAVRDGAADYACVPIENSIDGSVTPTLDSLAIGSPLQVFAETTL
MMAR_5390|M.marinum_M STPAALDAVRTGAAEFACVPIENSIDGSLAPTLDSLAIGSPLQVFAETTL
MUL_5011|M.ulcerans_Agy99 STPAALDAVRTGAAEFACVPIENSIDGSLAPTLDSLAIGSPLQVFAETTL
.: ** *: *::******.*::*.: ****.** * **::** .*
MSMEG_6418|M.smegmatis_MC2_155 DVAFTIVVRPGHDGP-VRTVAAFPVAAAQVRHWLAANLRDAEVVPAHSNA
TH_1472|M.thermoresistible__bu DVAFTIVTRPGTEPPDIATVAAFPVAAAQVRHWLADHLPHAQLVPATSNA
Mflv_1145|M.gilvum_PYR-GCK DVSFTIAVRPGVTAADVRTVAAFPVAAAQVKRWLSENLPNVELVPSNSNA
Mvan_5662|M.vanbaalenii_PYR-1 DVSFTIAVRPGTAAADVRTVAAYPVAAAQVRRWLAAHLPEAEVVPANSNA
MAB_0132|M.abscessus_ATCC_1997 PVSFTIAVRPGTAAGDVKTVAGFPIAAAQVREWLATNLPDAELVAANSNA
Mb3868c|M.bovis_AF2122/97 DVTFSIVVKPGRNAADVRTLAAFPVAAAQVRQWLAAHLPAADLRPAYSNA
Rv3838c|M.tuberculosis_H37Rv DVTFSIVVKPGRNAADVRTLAAFPVAAAQVRQWLAAHLPAADLRPAYSNA
MLBr_00078|M.leprae_Br4923 DVEFNIVVKPGITAADIRTLAAFPVAAAQVRQWLAAHLAGAELRPAYSNA
MAV_0188|M.avium_104 DVAFSIVVKPGLSAADVRTLAAIGVAAAQVRQWVAANLAGAQLRPAYSNA
MMAR_5390|M.marinum_M DVAFSIVVRPGVGAADVRTLAAFPVAAAQVRQWLTAHLPSVELHPAYSNA
MUL_5011|M.ulcerans_Agy99 DVAFSIVVKPGVGAADVRTLAAFPVAAAQVRQWLTAHLPNVELHPAYSNA
* *.*..:** : *:*. :*****:.*:: :* .:: .: ***
MSMEG_6418|M.smegmatis_MC2_155 AAAHDVAEGRADAGVSTRLAAERCGLDIMAADVVDEPNARTRFVLVGLPG
TH_1472|M.thermoresistible__bu AAAQDVAAGAADAGVSTALAAERYGLAVLATDVVDEPNARTRFVLVGQPA
Mflv_1145|M.gilvum_PYR-GCK AAARDVADGRAEAAVSTALATERYGLDTLAAGIVDEPNARTRFVLVGCPG
Mvan_5662|M.vanbaalenii_PYR-1 AAAQDVAAGRADAGVSTALATQRYGLEALAADVVDEPNARTRFVLVGRPG
MAB_0132|M.abscessus_ATCC_1997 AAAEDVKAERADAGVCTEWAAQRLGLHALASGVVDEAHAHTRFVLVGRPG
Mb3868c|M.bovis_AF2122/97 DAARQVADGLVDAAVTSPLAAARWGLAALADGVVDESNARTRFVLVGRPG
Rv3838c|M.tuberculosis_H37Rv DAARQVADGLVDAAVTSPLAAARWGLAALADGVVDESNARTRFVLVGRPG
MLBr_00078|M.leprae_Br4923 DAARQVAYGQVDAAVTSPLAATRWGLIALAAGIVDEPNARTRFVLVGMPG
MAV_0188|M.avium_104 DAAQQVAEGRADAAVTSPLAAARWGLDTLADGVVDEPNARTRFVLVGPPA
MMAR_5390|M.marinum_M DAARQVAEGQVDAAVTSPLAAAHWALQSLADGVVDESNARTRFLLIGVPG
MUL_5011|M.ulcerans_Agy99 DGARQVAEGQVDAAVTSPLAAAHWALQSLADGVVDESNARTRFLLIGVPG
.*.:* .:*.* : *: : .* :* .:***.:*:***:*:* *.
MSMEG_6418|M.smegmatis_MC2_155 TPPPATGADRTAVVLRLVNEPGALVSAMTEFSIRDIDLTRIESRPTRTEL
TH_1472|M.thermoresistible__bu RPPRRTGADRTSVVLRLANVPGALVTALTELAVRDIDLTRIESRPTRTGL
Mflv_1145|M.gilvum_PYR-GCK PPPKRTGSDRTSVVLRLDNVPGALVTAMNELAIRGIDLTGIESRPTRTEL
Mvan_5662|M.vanbaalenii_PYR-1 PPPKCTGADRTSVVLQLDNVPGALVSAMTELAVRDIDLTRIESRPTRTGL
MAB_0132|M.abscessus_ATCC_1997 PPPAATGADRTSVVLGLGNVPGALAAAMNEFAIRDIDLTRIESRPTRTGL
Mb3868c|M.bovis_AF2122/97 PPPARTGADRTSAVLRIDNQPGALVAALAEFGIRGIDLTRIESRPTRTEL
Rv3838c|M.tuberculosis_H37Rv PPPARTGADRTSAVLRIDNQPGALVAALAEFGIRGIDLTRIESRPTRTEL
MLBr_00078|M.leprae_Br4923 PPPARTGTDRTSAVLRIDNAPGMLVAALAEFGIRGIDLTRIESRPTRTEL
MAV_0188|M.avium_104 PPPARTGADRTSVVLRIDNAPGALLAALAEFGIRGIDLTRIESRPTRTGL
MMAR_5390|M.marinum_M PPPPRTGTDRTSVVLRIANVPGALLDALTEFGMRGIDLTRIESRPTRTGL
MUL_5011|M.ulcerans_Agy99 PPPPRTGTDRTSAVLRIANVPGALLDALTEFGMRGIDLTRIESRPTRTGL
** **:***:.** : * ** * *: *:.:*.**** ******** *
MSMEG_6418|M.smegmatis_MC2_155 GTYMFFLDCAGHIDDDPVAEALKALHRRCVDVRYLGSWPTESAA--GAPP
TH_1472|M.thermoresistible__bu GSYMFFLDMVGHIDDDAVAGALMALHRRCADVRYLGSWPTGSVV--GAPP
Mflv_1145|M.gilvum_PYR-GCK GTYRFYLDFVGHIDDDAVAGALRALHRRCADVRYLGSWPTGETG--GAAP
Mvan_5662|M.vanbaalenii_PYR-1 GTYKFFLDFVGHIEDPPVAEALRALHRRCADVRYLGSWPTGDVV--GAAP
MAB_0132|M.abscessus_ATCC_1997 GTYRFFLDCVGHIDDIAVGEALKGLHRRCEDVRYLGSWPRGTTAPTGANP
Mb3868c|M.bovis_AF2122/97 GTYLFFVDCVGHIDDEAVAEALKAVHRRCADVRYLGSWPTGPAAG--AQP
Rv3838c|M.tuberculosis_H37Rv GTYLFFVDCVGHIDDEAVAEALKAVHRRCADVRYLGSWPTGPAAG--AQP
MLBr_00078|M.leprae_Br4923 GTYLFFVDCVGHIDDGVVAEALKALHRRCADVCYLGSWPAGLATGPTVSP
MAV_0188|M.avium_104 GIYRFFADCVGHIDDEPVAEALKALHRRCADVRYLGSWPTGTPAG--ALP
MMAR_5390|M.marinum_M GTYMFFVDCVGHIADDAVAEALKALHRRCADVRYLGSWPTGQTYA--GQP
MUL_5011|M.ulcerans_Agy99 GTYMFFIDCVGHIADDAVAEALKALHRRCADVRYLGSWPTGQTYA--AQP
* * *: * .*** * *. ** .:**** ** ****** *
MSMEG_6418|M.smegmatis_MC2_155 PRLDEATTWLEGLRAG-----SGGA-------
TH_1472|M.thermoresistible__bu PPLDEQARWLARLREGKPVSETGGGP------
Mflv_1145|M.gilvum_PYR-GCK PPLDEATAWLQRLREGRP--------------
Mvan_5662|M.vanbaalenii_PYR-1 PPMDESASWLEGLREGRP--------------
MAB_0132|M.abscessus_ATCC_1997 PVLDEASGWLAETREGRLR-------------
Mb3868c|M.bovis_AF2122/97 PLVDEASRWLARLRAGKPEQTLVRPDDQGAQA
Rv3838c|M.tuberculosis_H37Rv PLVDEASRWLARLRAGKPEQTLVRPDDQGAQA
MLBr_00078|M.leprae_Br4923 PPPDEASRWLARLRAGKPDQ---ASEPGGGKL
MAV_0188|M.avium_104 PSTEEAVRWLAAVRDGKPEP------PGESRR
MMAR_5390|M.marinum_M PPADEAAIWLQQLREGKPEAS-----PGPPL-
MUL_5011|M.ulcerans_Agy99 PPADEAAIWLQQLREGKPEAS-----PEPPL-
* :* ** * *