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VSIRLRAEMADLPAYAPGKTVPGAIKIASNETVHGPLPSVREAILKATDLINRYPDNGYLDLRERLAKHV NFAPENISVGCGSVSLCQQLIQITSSVGDEVLFAWRSFEIYPLQVRTAGATPVAVALRDHTHDLDAMLAA ITDRTRLIFVCNPNNPTSTVVDPGELARFVAAVPPHILVVLDEAYVEYIRDGLLPDSLGLVREHRNVVVL RTFSKAYGLAGLRVGYAVADPEIVTALGKVYVPFSATSVSQAAAIACLDAADELLARTDAVVAERTRVSD ALRAAGYTLPPSQANFVWLPLAERTLDFVARAADNRIIVRPYGEDGVRVTIGAPHENDAFLDFAQRWIAP GGAGPRTGDSA
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. smegmatis MC2 155 | MSMEG_6351 | hisC | - | 100% (361) | putative aminotransferase |
M. smegmatis MC2 155 | MSMEG_1491 | - | 8e-44 | 35.81% (310) | histidinol-phosphate aminotransferase 2 |
M. smegmatis MC2 155 | MSMEG_3206 | hisC | 1e-37 | 34.59% (344) | histidinol-phosphate aminotransferase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3800 | hisC2 | 1e-151 | 74.79% (349) | putative aminotransferase |
M. gilvum PYR-GCK | Mflv_1195 | - | 1e-166 | 83.95% (349) | putative aminotransferase |
M. tuberculosis H37Rv | Rv3772 | hisC2 | 1e-151 | 74.50% (349) | putative aminotransferase |
M. leprae Br4923 | MLBr_01258 | hisC | 7e-38 | 31.98% (344) | histidinol-phosphate aminotransferase |
M. abscessus ATCC 19977 | MAB_0220c | - | 1e-144 | 72.05% (347) | putative aminotransferase |
M. marinum M | MMAR_5326 | hisC2 | 1e-142 | 71.19% (354) | histidinol-phosphate aminotransferase HisC2 |
M. avium 104 | MAV_0250 | hisC | 1e-134 | 68.38% (351) | putative aminotransferase |
M. thermoresistible (build 8) | TH_1662 | hisC2 | 1e-161 | 79.66% (349) | PROBABLE HISTIDINOL-PHOSPHATE AMINOTRANSFERASE HISC2 |
M. ulcerans Agy99 | MUL_4407 | hisC2 | 1e-140 | 70.34% (354) | putative aminotransferase |
M. vanbaalenii PYR-1 | Mvan_5611 | - | 1e-169 | 85.88% (347) | putative aminotransferase |
CLUSTAL 2.0.9 multiple sequence alignment Mb3800|M.bovis_AF2122/97 ---------MTARLRPELAGLPVYVPGKTVPGAIKLASNETVFGP----L Rv3772|M.tuberculosis_H37Rv ---------MTARLRPELAGLPVYVPGKTVPGAIKLASNETVFGP----L MMAR_5326|M.marinum_M ---------MTARLRPVLAGLPVYVPGKTVPGAIKLASNETVFGP----L MUL_4407|M.ulcerans_Agy99 ---------MTAHLRPVLAGLPVYVPGKTVPGAIKLASNETVFGP----L MAV_0250|M.avium_104 ---------MTARLRPELAGLPVYVPGKNVPGSIKLASNETVYGP----L Mflv_1195|M.gilvum_PYR-GCK MRAGHKLSQVSARLRPELADLPAYTPGRTVPGAIKIASNETVHGP----L Mvan_5611|M.vanbaalenii_PYR-1 ---------MSARLRPELADLPAYAPGKTVPGAIKIASNETVHGP----L MSMEG_6351|M.smegmatis_MC2_155 ---------MSIRLRAEMADLPAYAPGKTVPGAIKIASNETVHGP----L TH_1662|M.thermoresistible__bu ---------VTARLRPELADIPAYVPGKMVPGAIKIASNETVHPP----L MAB_0220c|M.abscessus_ATCC_199 ---------MPARLRPELTELPAYTPGRNVPGAIKLASNETVQEP----L MLBr_01258|M.leprae_Br4923 -MNVPEPTLDDLPLRDNLRGKSPYG-AMQLLVPVLLNTNENPHPPTKALV ** : . * . : .: : :**. * : Mb3800|M.bovis_AF2122/97 PSVRAAIDRATDTVNRYPDNGCVQLKAALARHLG----PDFAPEHVAVGC Rv3772|M.tuberculosis_H37Rv PSVRAAIDRATDTVNRYPDNGCVQLKAALARHLG----PDFAPEHVAVGC MMAR_5326|M.marinum_M PSVRAAIEHATQSINRYPDNGCLAVKAALARHVSSLSAADFGPEHIAVGC MUL_4407|M.ulcerans_Agy99 PSVRAAIEHATQSINRYPDNGCLAVKAALARHVSSLSAADFGPEHIAVGC MAV_0250|M.avium_104 PSVHAAIERAVAIVNRYPDNACVDLKAALAMHLG----SDVAPEQIAVGS Mflv_1195|M.gilvum_PYR-GCK PSVRAAIADAVGGINRYPDNGYVDLNERLAKYVG------FAPENISVGC Mvan_5611|M.vanbaalenii_PYR-1 PSVRAAIEKAIDGINRYPDNGYVELRERLAKHVN------FAPEYISVGC MSMEG_6351|M.smegmatis_MC2_155 PSVREAILKATDLINRYPDNGYLDLRERLAKHVN------FAPENISVGC TH_1662|M.thermoresistible__bu PSVREAIARAGETLNRYPDNGYLDLRDRLARHVG------FAPEHISVGC MAB_0220c|M.abscessus_ATCC_199 PSVRAALAEAGSLINRYPDNGYAELRSHLAKHVD------MPPEHIAVGC MLBr_01258|M.leprae_Br4923 DDVVRSVQKVAVDLHRYPDRDAVALRQDLASYLTAQTGIRLGVENIWAAN .* :: . ::****. :. ** :: . * : .. Mb3800|M.bovis_AF2122/97 GSVSLCQQLVQVTASVGDEVVFGWRSFELYPPQVR-VAGAIPIQVPLTDH Rv3772|M.tuberculosis_H37Rv GSVSLCQQLVQVTASVGDEVVFGWRSFELYPPQVR-VAGAIPIQVPLTDH MMAR_5326|M.marinum_M GSVSLCQQLVQITASVGDEVIFGWRSFELYPPQVQ-VAGATAIQVPLTNH MUL_4407|M.ulcerans_Agy99 GSVSLCQQLVQITASVGDEVIFGWRSFELYPPQVQ-VAGATAIQVPLTNH MAV_0250|M.avium_104 GSVTLCQQLVQITSAAGDEVMMGWRSFECYLPIVQ-VAGAIAVKVPLREH Mflv_1195|M.gilvum_PYR-GCK GSVSLCQQLIQITATVGDEVLFGWRSFEIYPLQVR-TAGATPVQVPLTDH Mvan_5611|M.vanbaalenii_PYR-1 GSVSLCQQLIQITSTVGDEVLFGWRSFEIYPLQVR-TAGATPVQVPLTDH MSMEG_6351|M.smegmatis_MC2_155 GSVSLCQQLIQITSSVGDEVLFAWRSFEIYPLQVR-TAGATPVAVALRDH TH_1662|M.thermoresistible__bu GSVSLCQQLVQITAGAGDEVLFGWRSFEIYPLQVR-TAGAVPVQVPLTDH MAB_0220c|M.abscessus_ATCC_199 GSVSLCQQLVQITATVGDEVLFGWRSFETYPLVVR-VAGATPVQVPLVDH MLBr_01258|M.leprae_Br4923 GSNEILQQLLQAFGGPGRSAIGFVPSYSMHPIIADGTHTEWLETVRADDF ** : ***:* . * ..: *:. : . . * :. Mb3800|M.bovis_AF2122/97 TFDLYAMLAAVTDRTR-LIFVCNPNNPTSTVVGPDALARFVEAVPAHILI Rv3772|M.tuberculosis_H37Rv TFDLYAMLATVTDRTR-LIFVCNPNNPTSTVVGPDALARFVEAVPAHILI MMAR_5326|M.marinum_M TFDLEAMLAAVTERTR-LIIVCNPNNPTSTVVQPEALAEFVRSVPPHILV MUL_4407|M.ulcerans_Agy99 TFDLEAMLAAVTERTR-LIIVCDPNNPTSTVVQPEALAEFVRSVPPHILV MAV_0250|M.avium_104 TYDLDAMLAAITDRTR-LIFVCNPNNPTSTVVDPDALVRFVDAVPADILI Mflv_1195|M.gilvum_PYR-GCK TFDLDAMLAAITDRTR-LIFVCNPNNPSSTVVDPGALARFVAAVPPHILV Mvan_5611|M.vanbaalenii_PYR-1 TFDLDAMLAAITDRTR-LIFVCNPNNPTSTVVDPDALARFVEAVPPHIMV MSMEG_6351|M.smegmatis_MC2_155 THDLDAMLAAITDRTR-LIFVCNPNNPTSTVVDPGELARFVAAVPPHILV TH_1662|M.thermoresistible__bu TFDLDAILAAITDRTR-LIFICNPNNPTSTVVDPDALARFVAAVPEHILI MAB_0220c|M.abscessus_ATCC_199 TYDLAAMAAAVTDVTR-LIFVCNPNNPTGTVVRPAELRRFVESVPPHILI MLBr_01258|M.leprae_Br4923 SLDVEAAVTAVADRKPDVVFIASPNNPSGQSISLADLRRLLDVVPG--IL : *: * ::::: . ::::..****:. : * .:: ** :: Mb3800|M.bovis_AF2122/97 AIDEAYVEYIRDGMRPDSLGLVRAH-NNVVVLRTFSKAYGLAGLRIGYAI Rv3772|M.tuberculosis_H37Rv AIDEAYVEYIRDGMRPDSLGLVRAH-NNVVVLRTFSKAYGLAGLRIGYAI MMAR_5326|M.marinum_M AIDEAYVEYLRDGTVPDSPHLVRTH-SNVVVLRTFSKAYGLAGLRVGYAV MUL_4407|M.ulcerans_Agy99 AIDEAYVEYLRDGTVPDSPHLVRTH-SNVVVLRTFSKAYGLAGLRVGYAV MAV_0250|M.avium_104 AIDEAYVEYIRDGLLPNSLELALSR-SNVVVLRTFSKAYGLAGLRVGYAI Mflv_1195|M.gilvum_PYR-GCK VLDEAYIEYVRGDLVPDSFGLVRAH-SNVVVLRTFSKAYGLAGLRIGYAV Mvan_5611|M.vanbaalenii_PYR-1 VVDEAYVEYIRDGLAPDSFGLVRAH-SNVVVLRTFSKAYGLAGLRIGYAV MSMEG_6351|M.smegmatis_MC2_155 VLDEAYVEYIRDGLLPDSLGLVREH-RNVVVLRTFSKAYGLAGLRVGYAV TH_1662|M.thermoresistible__bu ALDEAYIEYVRPPFVPDSLGLVRAH-DNVVVLRTFSKAYGLAGLRVGYAV MAB_0220c|M.abscessus_ATCC_199 AIDEAYVEYVREDFT-DSLALVREH-PNVVVLRTFSKAYGLAGLRVGYAV MLBr_01258|M.leprae_Br4923 IVDEAYGEFS---SRPSAVALVGEYPTKIVVTRTTSKAFAFAGGRLGYLI :**** *: .: *. ::** ** ***:.:** *:** : Mb3800|M.bovis_AF2122/97 GHPDVITALDKVYVPFTVSSIGQAAAIASLDAADELLARTDTVVAERARV Rv3772|M.tuberculosis_H37Rv GHPDVITALDKVYVPFTVSSIGQAAAIASLDAADELLARTDTVVAERARV MMAR_5326|M.marinum_M GQPDVIAALDKVYVPFTVSSLAQAAAIASVQAADELLARTDAVVAERGRV MUL_4407|M.ulcerans_Agy99 GQPDVIAPLDKVYVPFTVSSLAQAAAIASVQAADELLARTDAVVAERGRV MAV_0250|M.avium_104 GHPELITALDKVVMPFAVTNVAQAAAIASLEASGELMARTDALVAERTRV Mflv_1195|M.gilvum_PYR-GCK ADPDIVTALSKVYVPFTATTVSQAAAIACLDAADELLERTDAVVAERTRV Mvan_5611|M.vanbaalenii_PYR-1 ADPDIIAALSKVYVPFTATSVSQAAAIACLDAADELLERTDAVVAERTRV MSMEG_6351|M.smegmatis_MC2_155 ADPEIVTALGKVYVPFSATSVSQAAAIACLDAADELLARTDAVVAERTRV TH_1662|M.thermoresistible__bu AAPEIVTALGKVYVPFSVSTLAQAAAIASLDAADELLARTDEVVAERARV MAB_0220c|M.abscessus_ATCC_199 GDPDVITTLGKVYVPFSASSLAQAAAVASLGAAEELLARTNDVVTERARV MLBr_01258|M.leprae_Br4923 ATPALVEAMLLVRLPYHLSSVTQAAARAALRHADDTLGSVAALIAERERV . * :: .: * :*: :.: **** *.: : : : . :::** ** Mb3800|M.bovis_AF2122/97 SAELRAAGFTLPPSQANFVWLPLGSRTQDFVEQAADARIVVRPYGTDG-V Rv3772|M.tuberculosis_H37Rv SAELRAAGFTLPPSQANFVWLPLGSRTQDFVEQAADARIVVRPYGTDG-V MMAR_5326|M.marinum_M SAELRAAGFTVPPSQANFVWLPLEDRTTDFVTQAAKAHIVVRPYGADG-V MUL_4407|M.ulcerans_Agy99 SAELRAAGFTVPPSQANFVWLPLEDRTTDFVTQAAKAHIVVRPYGADG-V MAV_0250|M.avium_104 STTLRDAGFELPPSQANFLWLPLGSRTEDFVQEAANARLVVRPFASEG-V Mflv_1195|M.gilvum_PYR-GCK SAALREAGYDLPPSQANFVWLPLVGRAQQFAADAADARIIVRPYGEDG-V Mvan_5611|M.vanbaalenii_PYR-1 SAALREAGYDLPPSQANFVWLPLVGRAQQFAADAANSRVIVRPYGEDG-V MSMEG_6351|M.smegmatis_MC2_155 SDALRAAGYTLPPSQANFVWLPLAERTLDFVARAADNRIIVRPYGEDG-V TH_1662|M.thermoresistible__bu TAALRDAGYTVPESGANFVWLPLAERTVDFVNSAAEDRLLVRPYGTDG-V MAB_0220c|M.abscessus_ATCC_199 TSALREAGYQVPPSQANFVWLPLGERSTEFAQASAEARIIVRPFGTDG-V MLBr_01258|M.leprae_Br4923 TKSLVHMGFRVIPSDANFVLFGHFSDAAGAWQHYLDTGVLIRDVGIPGYL : * *: : * ***: : : . :::* . * : Mb3800|M.bovis_AF2122/97 RVTVAAPEENDAFLRFARRWRSDQ---------- Rv3772|M.tuberculosis_H37Rv RVTVAAPEENDAFLRFARRWRSDQ---------- MMAR_5326|M.marinum_M RVTIAAPEENDALLRFARCWITHRDGAR------ MUL_4407|M.ulcerans_Agy99 RVTIAAPEENDALLRFARCWITHRDGAR------ MAV_0250|M.avium_104 RVTIGAPAENDALLQFACDWIARTER-------- Mflv_1195|M.gilvum_PYR-GCK RVTVASPDENDMFLDFARDWIARP---------- Mvan_5611|M.vanbaalenii_PYR-1 RVTIAAPHENDAFLGFARGWDGLR---------- MSMEG_6351|M.smegmatis_MC2_155 RVTIGAPHENDAFLDFAQRWIAPGGAGPRTGDSA TH_1662|M.thermoresistible__bu RVTVAAPHENDAFLSFATRWISER---------- MAB_0220c|M.abscessus_ATCC_199 RVTIGAPMENDAFLKFSRAWR------------- MLBr_01258|M.leprae_Br4923 RATTGLAEENDAFLKASSEIAATELAPATTLGAS *.* . . *** :* :