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SDFFTRASSMLTDMAAWSVRITDLNTGEILWEHDPERVLKTASVGKIFLLAEVARRFENRTLDPAEIVTA APEDVVADSGILYLLQGQDLRIDDLCLLIGAVSDNMATNILLRRLGLDEVQRATKDLGFTASGLRDRVRL NRSQDDPLTLSTGNAAELCEFVARLHSGDIHGAEVSRQVRTWLGVNTDLSMVARAFGLDPLAHTEPDRFA LWNKTGTISDARIDIGCATHGDRSVGYAVLANWAWGQDHRDPVLGTMGWLGCEIRRYLQNR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_6194 | - | - | 100% (272) | beta-lactamase related protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3624 | lpqF | 0.0001 | 27.78% (90) | lipoprotein LpqF |
| M. gilvum PYR-GCK | Mflv_1434 | - | 3e-05 | 31.87% (91) | beta-lactamase |
| M. tuberculosis H37Rv | Rv3593 | lpqF | 8e-05 | 26.85% (108) | lipoprotein LpqF |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | - | - | - | - | - |
| M. thermoresistible (build 8) | TH_1285 | - | 4e-06 | 29.07% (172) | beta-lactamase |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_2352 | - | 3e-05 | 28.57% (189) | Beta-lactamase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3624|M.bovis_AF2122/97 -MGPARLHNRRAGRRMLALSAAAALIVALASGCSSAPTPSANAANHGHRI
Rv3593|M.tuberculosis_H37Rv -MGPARLHNRRAGRRMLALSAAAALIVALASGCSSAPTPSANAANHGHRI
Mflv_1434|M.gilvum_PYR-GCK MRGLTPTPEAARARRGATVVVALLSVVALACGCAATRPAPADAA-YGAPI
TH_1285|M.thermoresistible__bu --------------------------------------------------
Mvan_2352|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6194|M.smegmatis_MC2_155 --------------------------------------------------
Mb3624|M.bovis_AF2122/97 DTRTPPGLRAQQTMDMLNSDWPIGEIGVGTLAAPGQVDTVKTTMEALWWD
Rv3593|M.tuberculosis_H37Rv DTRTPPGLRAQQTMDMLNSDWPIGEIGVGTLAAPGQVDTVKTTMEALWWD
Mflv_1434|M.gilvum_PYR-GCK QINTPQGLRAKQTMDMLNSDWPIGEVGVRTLAAPDLVEHVGVTLDRIWWD
TH_1285|M.thermoresistible__bu ------------VTGLSRRTLLIGGLAVAGAGLCG---------------
Mvan_2352|M.vanbaalenii_PYR-1 ------------MTEFSRRHVLFGGVSLAALAACSPQT------------
MSMEG_6194|M.smegmatis_MC2_155 ------------MSDFFTR-------------------------------
:
Mb3624|M.bovis_AF2122/97 RPFALAGVDIGASVAALHLISSYGAQQDIRIHTDDDGWVDRFDVETQAPS
Rv3593|M.tuberculosis_H37Rv RPFALAGVDIGASVAALHLISSYGAQQDIRIHTDDDGWVDRFDVETQAPS
Mflv_1434|M.gilvum_PYR-GCK RPFTLTDVDVGAGWATLDVQTSYGVAQTIRLRTDEQGLVDRFSVDLVPPE
TH_1285|M.thermoresistible__bu ----LAAPRIAHAAPAIHQR------------------------------
Mvan_2352|M.vanbaalenii_PYR-1 ---VLADP--VEPLPPLDQR------------------------------
MSMEG_6194|M.smegmatis_MC2_155 --------------------------------------------------
Mb3624|M.bovis_AF2122/97 IASWRDVDAVLSKTGARYSFQVAKVDNGRCDPVAGTSTGESLPLASIFKL
Rv3593|M.tuberculosis_H37Rv IASWRDVDAALSKTGARYSFQVAKVDNGRCDPVAGTNTGESLPLASIFKL
Mflv_1434|M.gilvum_PYR-GCK IDEWSDIDEQLTASGARYSYQVAKVDDGRCVKVAGSNTDLSLPLASIFKL
TH_1285|M.thermoresistible__bu ------LTGLENDHDQLIGLYAVDLGSGRTIAHR---EHESFAMCSTFKT
Mvan_2352|M.vanbaalenii_PYR-1 ------IEALGQRHNAQIGLYALDLDTQRGIEFG---ADEPFAMCSTFKA
MSMEG_6194|M.smegmatis_MC2_155 -------ASSMLTDMAAWSVRITDLNTGEILWEHD--PERVLKTASVGKI
. .:. . : .* *
Mb3624|M.bovis_AF2122/97 YVLHALAGAVQHNTVSWDDLLTVTAKSKAVGSSGL-ELPVGARVSVRTAA
Rv3593|M.tuberculosis_H37Rv YVLHALAGAVQHNTVSWDDLLTVTAKSKAVGSSGL-ELPVGARVSVRTAA
Mflv_1434|M.gilvum_PYR-GCK YVLLAVADAVKAGTLQWSDPLTITEEAKAVGSSGFDELEPGATVTVREAS
TH_1285|M.thermoresistible__bu YLAAATLQRVQQGELQLDQRIFVPPAAIVTHSPRS-EAAAGGHLTVAELC
Mvan_2352|M.vanbaalenii_PYR-1 YAAAAVLQRTQTGELTLNDAIPIEPGDIRPHSPVT-EPRVGTSMSLAELC
MSMEG_6194|M.smegmatis_MC2_155 FLLAEVARRFENRTLDPAEIVTAAPEDVVADSGIL-YLLQGQDLRIDDLC
: : : : : * * : : .
Mb3624|M.bovis_AF2122/97 EKMIATSDNMATDLLIERLGTRAIEEALASAGHHDPASMTPFPTMYELFS
Rv3593|M.tuberculosis_H37Rv EKMIATSDNMATDLLIERLGTRAIEEALASAGHHDPASMTPFPTMYELFS
Mflv_1434|M.gilvum_PYR-GCK QQMISASDNMATDLLIERLGPGAIERALAEAGHHDPASMTPFPTMHELFS
TH_1285|M.thermoresistible__bu AAILQVSDNGAANTLLQTLGGPPAVTEFARS-------IGDERSRLDRWE
Mvan_2352|M.vanbaalenii_PYR-1 QAALQQSDNAAANGLLRVLGGPQAITAFARS-------IGDHRTRLDRWE
MSMEG_6194|M.smegmatis_MC2_155 LLIGAVSDNMATNILLRRLGLDEVQRATKDLG-------FTASGLRDRVR
*** *:: *:. ** :
Mb3624|M.bovis_AF2122/97 VGWGKPDLRDQWKHATQQVRAQILRQTNSTPYQPDPTRAHTPASNYGAEW
Rv3593|M.tuberculosis_H37Rv VGWGKPDLRDQWKHATQQVRAQILRQTNSTPYQPDPTRAHTPASNYGAEW
Mflv_1434|M.gilvum_PYR-GCK VGWGTPDLREQWKKASPEGRAQLLQQTNSRPYEPDPKRTHMPASEYGAEW
TH_1285|M.thermoresistible__bu VALNSAVPGDPRDTSTPRALGEGYRTLLEGDVLAPPYREQLVEWMRTNET
Mvan_2352|M.vanbaalenii_PYR-1 VELNSALPGDPRDTSTPRALGDGYRNILTGDVLNPPTRRQLLDWMLANQT
MSMEG_6194|M.smegmatis_MC2_155 LNRSQDDP-LTLSTGNAAELCEFVARLHSGDIHGAEVSRQVRTWLGVNTD
: . . .. : :
Mb3624|M.bovis_AF2122/97 YGSAEDICRVHAALRADAV-----GPASPVRQIMSAVPGIQLDRSVWPYI
Rv3593|M.tuberculosis_H37Rv YGSAEDICRVHAALRADAV-----GPASPVRQIMSAVPGIQLDRSVWPYI
Mflv_1434|M.gilvum_PYR-GCK YGSAADICRLHAALQRSAV-----GEAAPVKDILSFLPGIDLDRAEWPYI
TH_1285|M.thermoresistible__bu SAMRPGLPPGWVSADKTGS-----GDYGTTNDVGLLYG------------
Mvan_2352|M.vanbaalenii_PYR-1 SSMRAGLPAGYTSADKTGS-----GDYGTTNDVGVAYG------------
MSMEG_6194|M.smegmatis_MC2_155 LSMVARAFGLDPLAHTEPDRFALWNKTGTISDARIDIG-----------C
. . .. :
Mb3624|M.bovis_AF2122/97 GAKAGGLPGDLTFSWYAVDKTGQPWVVSFQLNWPRDHGPTVTGWMLQVAR
Rv3593|M.tuberculosis_H37Rv GAKAGGLPGDLTFSWYAVDKTGQPWVVSFQLNWPRDHGPTVTGWMLQVAR
Mflv_1434|M.gilvum_PYR-GCK GAKAGNLPGDMTFSWYAVDRSGQPWVVSLQSNWPEFRSQTAAAWLMSIAR
TH_1285|M.thermoresistible__bu --PQGQRVVLAILTRSASDDPDAQNPRPLIGEITAAVLPELLGWPSAQ--
Mvan_2352|M.vanbaalenii_PYR-1 --PAGQQVLLSLMTRSAIDDPDAPSLRPLIGELAALALSELG--------
MSMEG_6194|M.smegmatis_MC2_155 ATHGDRSVGYAVLANWAWGQDHRDPVLGTMGWLGCEIRRYLQNR------
. :: * .
Mb3624|M.bovis_AF2122/97 QVFALIAPQ
Rv3593|M.tuberculosis_H37Rv QVFALIAPQ
Mflv_1434|M.gilvum_PYR-GCK QTFDLIPN-
TH_1285|M.thermoresistible__bu ---------
Mvan_2352|M.vanbaalenii_PYR-1 ---------
MSMEG_6194|M.smegmatis_MC2_155 ---------