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DRSRAVATLRRTVADFAAQVDGERWCVALSGGPDSLALTAVAAAERPTTALIVDHGLQTGSRAVAETARA QALSVGCVGAEIIPVVVGRSGGPEAAARKARYTALQAARDGAPVLLGHTLDDQAETVLLGLARGSGPRSI AGMRPHDPPWHRPLLGIRRTVTHAACEELGLKPWHDPHNFEPRFTRTRLRLDVMPLLEEVLGGGVAEALA RTATALREDTETLDEIARQALETSQTSARTPPGLDTEVLAGLPGAVRRRVIRAWLLTNGGTDLTDVQIRG VDRLVTDWRGQGGVAVGSNLSRQRLFVGRRHGELVLYTEPV*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_6111 | tilS | - | 100% (322) | tRNA(Ile)-lysidine synthetase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3649c | mesJ | 1e-118 | 69.75% (324) | cell cycle protein MESJ |
| M. gilvum PYR-GCK | Mflv_1411 | - | 1e-115 | 65.33% (323) | tRNA(Ile)-lysidine synthetase |
| M. tuberculosis H37Rv | Rv3625c | mesJ | 1e-118 | 69.75% (324) | cell cycle protein MESJ |
| M. leprae Br4923 | MLBr_00213 | mesJ | 1e-112 | 66.57% (329) | hypothetical protein MLBr_00213 |
| M. abscessus ATCC 19977 | MAB_0521 | - | 5e-90 | 61.49% (296) | putative tRNA(Ile)-lysidine synthase |
| M. marinum M | MMAR_5125 | mesJ | 1e-116 | 69.51% (328) | cell cycle protein MesJ |
| M. avium 104 | MAV_0531 | tilS | 1e-120 | 70.37% (324) | tRNA(Ile)-lysidine synthetase |
| M. thermoresistible (build 8) | TH_1410 | mesJ | 1e-114 | 69.77% (311) | POSSIBLE CELL CYCLE PROTEIN MESJ |
| M. ulcerans Agy99 | MUL_4201 | mesJ | 1e-115 | 69.21% (328) | cell cycle protein MesJ |
| M. vanbaalenii PYR-1 | Mvan_5378 | - | 1e-116 | 69.11% (327) | tRNA(Ile)-lysidine synthetase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3649c|M.bovis_AF2122/97 MDRQSAVAQLRAAAEQFARVHLDACDRWSVGLSGGPDSLALTAVAAR-LW
Rv3625c|M.tuberculosis_H37Rv MDRQSAVAQLRAAAEQFARVHLDACDRWSVGLSGGPDSLALTAVAAR-LW
MMAR_5125|M.marinum_M MDRQGAVAQLRRAVEKFASTHLDATDRWSIGLSGGPDSLALTAVAAR-LR
MUL_4201|M.ulcerans_Agy99 MDRQGAVAQLRRAVENFASTHLDATDRWSIGLSGGPDSLALTAVAAR-LR
MLBr_00213|M.leprae_Br4923 MDRQGAVGQLRRTVEEFAGTYCDIDDQWCVALSGGSDSLALTAVAAQ-LR
MAV_0531|M.avium_104 MDRPGALDRLRTAVEAFSTAHLGAVERWCVALSGGPDSLALTAVAAR-LR
MSMEG_6111|M.smegmatis_MC2_155 MDRSRAVATLRRTVADFA-AQVDG-ERWCVALSGGPDSLALTAVAAA-ER
Mflv_1411|M.gilvum_PYR-GCK MDRSGPVVELRTALVDFARTHRFPP-PWCVALSGGPDSLALTAVAAT-LH
Mvan_5378|M.vanbaalenii_PYR-1 MDRPGAVAELRTAVAGFVRDHAAASGPWCVALSGGADSLALTAVAAA-LR
TH_1410|M.thermoresistible__bu MDRPGAVAALRSALAAFERAWAGADDRWCVALSGGADSLALTAVAAE-LK
MAB_0521|M.abscessus_ATCC_1997 ------------------------MTEVAVALSGGADSLALAAAAVARAW
.:.****.*****:*.*.
Mb3649c|M.bovis_AF2122/97 PTTALIVDHGLQPGSATVAETARIQAISLGCVDARVLCVQVG----AAGG
Rv3625c|M.tuberculosis_H37Rv PTTALIVDHGLQPGSATVAETARIQAISLGCVDARVLCVQVG----AAGG
MMAR_5125|M.marinum_M PTTALIVDHGLQPDSAAVSETARAQAVSLGCVAARVLRVQVGNPAGAGGG
MUL_4201|M.ulcerans_Agy99 PTTALIVDHGLQPDSAAVSETARAQAVSLGCVTARVLRVQVGNPAGAGGG
MLBr_00213|M.leprae_Br4923 STTAFIVDHGLQSDSAAVAETARKQAISLGCVDAQVLCVQIDPPFGPKGG
MAV_0531|M.avium_104 PTTAVIVDHGLQPDSAAVAQTARAQAIALGCVAAQVISVHVD----GEGG
MSMEG_6111|M.smegmatis_MC2_155 PTTALIVDHGLQTGSRAVAETARAQALSVGCVGAEIIPVVVG----RSGG
Mflv_1411|M.gilvum_PYR-GCK PTTALIVDHRLQPGSADVAAAAREQALALGCVAAQVLPVDVG----SPGG
Mvan_5378|M.vanbaalenii_PYR-1 PTTALIVDHGLQPGSARVAATARDQAMALGCVGAQVLCVEVG----VGGG
TH_1410|M.thermoresistible__bu PTTALIVDHQLQPGSAEVAQTARRQALQLGCVAARILRVQVG----TAGG
MAB_0521|M.abscessus_ATCC_1997 SVTALIVDHGLQQDSAQVAARARSQALALGCSDAVVLSVTVD----GVGG
..**.**** ** .* *: ** **: :** * :: * :. **
Mb3649c|M.bovis_AF2122/97 REAAARSARYSALEEHRDG-PVLLAHTLDDQAETVLLGLGRGSGARSIAG
Rv3625c|M.tuberculosis_H37Rv REAAARSARYSALEEHRDG-PVLLAHTLDDQAETVLLGLGRGSGARSIAG
MMAR_5125|M.marinum_M LEAAARTARYGALDAHRDG-PVLLAHTLDDQAETVLLGLGRGSGARSIAG
MUL_4201|M.ulcerans_Agy99 LEAAARTARYGALDAHRDG-PVLLAHTLDDQAETVLLGLGRGSGARSIAG
MLBr_00213|M.leprae_Br4923 LEAAARAARYAVLGANRNG-PVLLAHTLDDQAETVLLGLGRGSGARSIAG
MAV_0531|M.avium_104 PEAAARRARYAALAAHRDG-PVLLGHTLDDQAETVLLGLGRGSGVRSIAG
MSMEG_6111|M.smegmatis_MC2_155 PEAAARKARYTALQAARDGAPVLLGHTLDDQAETVLLGLARGSGPRSIAG
Mflv_1411|M.gilvum_PYR-GCK PEAAARTARYRALDDARDGKPVLLGHTLDDQAETVLLGLGRGSGPRSIAG
Mvan_5378|M.vanbaalenii_PYR-1 PEAAARAARYRALEEARRGAPVLLAHTLDDQAETVLLGLGRGSGARSIAG
TH_1410|M.thermoresistible__bu PEAAARTARYEALSTARGEAPVLLGHTLDDQAETVLLGLGRGSGPRSIAG
MAB_0521|M.abscessus_ATCC_1997 LEAAARSARYAALEQARDGRPVLLAHTLDDQAETVLLGLGRGSGARSIAG
***** *** .* * ****.**************.**** *****
Mb3649c|M.bovis_AF2122/97 MRPYDPPWCRPLLGVRRSVTHAACRELGLTAWQDPHNTDRRFTRTRLRTE
Rv3625c|M.tuberculosis_H37Rv MRPYDPPWCRPLLGVRRSVTHAACRELGLTAWQDPHNTDRRFTRTRLRTE
MMAR_5125|M.marinum_M MRPHDPPWCRPLLGVRRGVTHDACRELGLTAWQDPHNSDRRFTRTRLRAE
MUL_4201|M.ulcerans_Agy99 MRPHDPPWCRPLLGVRRGVTHDACRELGLTAWQDPHNSDRRFTRTRLRAE
MLBr_00213|M.leprae_Br4923 MRPHDPPWCRPLLGVRRSVPRAACHELGLNAWQDPHNTDCRYTRTRLRLE
MAV_0531|M.avium_104 MRPHDPPWCRPLLGQRRAVTHAACAELGLTAWQDPHNSDRRFTRARLRAE
MSMEG_6111|M.smegmatis_MC2_155 MRPHDPPWHRPLLGIRRTVTHAACEELGLKPWHDPHNFEPRFTRTRLRLD
Mflv_1411|M.gilvum_PYR-GCK MRPYDLPWGRPLLGVRRDTTHRACAELGLNPWQDPHNLDPRYTRVRLRTE
Mvan_5378|M.vanbaalenii_PYR-1 MRPSDPPWCRPLLGVRRAVTRLACAELGLTPWQDPHNTDRRFTRVRLRTE
TH_1410|M.thermoresistible__bu MRPHDPPWYRPLLGVRRSVTVAACAELGLTPWQDPHNADPRFTRSRLRTE
MAB_0521|M.abscessus_ATCC_1997 MRPWDDPWGRPFLDRRRTETRSYCDELAITAWEDPHNVDSRFVRVRLRHE
*** * ** **:*. ** . * **.:..*.**** : *:.* *** :
Mb3649c|M.bovis_AF2122/97 VLPLLEDVLGGGVAEALARTATALREDTDLIDTIAAQALPGAAVAGSRG-
Rv3625c|M.tuberculosis_H37Rv VLPLLEDVLGGGVAEALARTATALREDTDLIDTIAAQALPGAAVAGSRG-
MMAR_5125|M.marinum_M VLPLLEEVLGGGVAAALARTATALRADTELLDAIAAEALPTAVVDSG---
MUL_4201|M.ulcerans_Agy99 VLPLLEEVLGGGVAAALARTATALRADTELLDAIAAEALPTAVVDFG---
MLBr_00213|M.leprae_Br4923 VLPLLEDVLGGGVVEALARTATALREDTELIDTFAAQALPNICAGSG---
MAV_0531|M.avium_104 VLPLLEEVLGGGVAEALARTATALREDNEVLDALAERALPAAQAGAG---
MSMEG_6111|M.smegmatis_MC2_155 VMPLLEEVLGGGVAEALARTATALREDTETLDEIARQALETSQTSARTP-
Mflv_1411|M.gilvum_PYR-GCK VLPLLEDVLGGGVAEALARTAAALREDTDVLDALAA---EAVAPGDAD--
Mvan_5378|M.vanbaalenii_PYR-1 VLPLLEDVLGGGVAEALARTATALREDTDALDGIAA---RIVTVPGAD--
TH_1410|M.thermoresistible__bu VMPLLEEVLGGGVAEALARTAAALREDTDALDELAARELRRVVVGGEEGG
MAB_0521|M.abscessus_ATCC_1997 VLPLLEEVLGGGVAEALARTALSLQDDGDALDAQARAAFPGAQG------
*:****:******. ****** :*: * : :* *
Mb3649c|M.bovis_AF2122/97 -----QELSTSALTALPDAVRRRVIRGWLLAGGATGLTDRQIRGVDRLVT
Rv3625c|M.tuberculosis_H37Rv -----QELSTSALTALPDAVRRRVIRGWLLAGGATGLTDRQIRGVDRLVT
MMAR_5125|M.marinum_M -------LDTSVLATLPDPVRRRVIRSWLLAGGAIGLTDKQIRGVDALVT
MUL_4201|M.ulcerans_Agy99 -------LDTSVLATLPDPVRRRVIRSWLLAGGAIGLTDKQIRGVDALVT
MLBr_00213|M.leprae_Br4923 -------LHARALAALPDAVRRRVIRGWLLNGGATGLTDKQIRGVDTLVT
MAV_0531|M.avium_104 -------LQVAALAGLDAPVRRRVIRAWLLAGGATGLTDKQIRGVDNLIT
MSMEG_6111|M.smegmatis_MC2_155 -----PGLDTEVLAGLPGAVRRRVIRAWLLTNGGTDLTDVQIRGVDRLVT
Mflv_1411|M.gilvum_PYR-GCK -------LDVTALADLPTALRRRAVRGWLLAAGARDLTDKHLRAVDALIT
Mvan_5378|M.vanbaalenii_PYR-1 -------LDTAVLTPLPAAVRRRVIRGWLLGGGANGLTDKQIRAVDDLVV
TH_1410|M.thermoresistible__bu ETGAATGLDARALERLPTAIRRRVIRVWLLDGGAANLSDHQIRAVDTLVT
MAB_0521|M.abscessus_ATCC_1997 -------LAISDLRGLTPAVRRRVIRLWLLAGGAQDLNDNQIRAVDALVT
* * * .:***.:* *** *. .*.* ::*.** *:.
Mb3649c|M.bovis_AF2122/97 AWRGQGGVAVGSTLRGQRLVAGRRDGVLVLRREPV---------------
Rv3625c|M.tuberculosis_H37Rv AWRGQGGVAVGSTLRGQRLVAGRRDGVLVLRREPV---------------
MMAR_5125|M.marinum_M AWRGQGGVAVGSNLKARRLVAGRGGGLLTLRSEPI---------------
MUL_4201|M.ulcerans_Agy99 AWRGQGGVAFGSNLKARRLVAGRGGGLLTLRSEPI---------------
MLBr_00213|M.leprae_Br4923 AWRGQGGVAVGSTLRGQRLIASRYDGVLTLHCAPV---------------
MAV_0531|M.avium_104 AWRGQGGVAVGSSQPGERLFAGRRDGVLTLWREPVR--------------
MSMEG_6111|M.smegmatis_MC2_155 DWRGQGGVAVGSNLSRQRLFVGRRHGELVLYTEPV---------------
Mflv_1411|M.gilvum_PYR-GCK DWHGQGGVAVPGGLTRERLFVARNRNRLGMYREPVAQ--------RQG--
Mvan_5378|M.vanbaalenii_PYR-1 DWHGQGGVAVPGGLARERLFAGRRKDVLTLYREPVAE--------RQR--
TH_1410|M.thermoresistible__bu GWRGQGGVAVGSPLRGXXXATARACGVSRSGTPALTSGTCRRCRLRRGVS
MAB_0521|M.abscessus_ATCC_1997 QWRGQGGVAVGADLRYQRLVASRSGEQLVLSVHDVAR-------------
*:******. . ..* :
Mb3649c|M.bovis_AF2122/97 -
Rv3625c|M.tuberculosis_H37Rv -
MMAR_5125|M.marinum_M -
MUL_4201|M.ulcerans_Agy99 -
MLBr_00213|M.leprae_Br4923 -
MAV_0531|M.avium_104 -
MSMEG_6111|M.smegmatis_MC2_155 -
Mflv_1411|M.gilvum_PYR-GCK -
Mvan_5378|M.vanbaalenii_PYR-1 -
TH_1410|M.thermoresistible__bu G
MAB_0521|M.abscessus_ATCC_1997 -