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M. abscessus ATCC 19977 MAB_0521 (-)

annotation: putative tRNA(Ile)-lysidine synthase
coordinates: 522247 - 523137
length: 296

VTEVAVALSGGADSLALAAAAVARAWSVTALIVDHGLQQDSAQVAARARSQALALGCSDAVVLSVTVDGV
GGLEAAARSARYAALEQARDGRPVLLAHTLDDQAETVLLGLGRGSGARSIAGMRPWDDPWGRPFLDRRRT
ETRSYCDELAITAWEDPHNVDSRFVRVRLRHEVLPLLEEVLGGGVAEALARTALSLQDDGDALDAQARAA
FPGAQGLAISDLRGLTPAVRRRVIRLWLLAGGAQDLNDNQIRAVDALVTQWRGQGGVAVGADLRYQRLVA
SRSGEQLVLSVHDVAR
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. abscessus ATCC 19977MAB_0521--100% (296)putative tRNA(Ile)-lysidine synthase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3649cmesJ3e-9968.15% (292) cell cycle protein MESJ
M. gilvum PYR-GCKMflv_1411-2e-9263.01% (292) tRNA(Ile)-lysidine synthetase
M. tuberculosis H37RvRv3625cmesJ3e-9968.15% (292) cell cycle protein MESJ
M. leprae Br4923MLBr_00213mesJ7e-9264.60% (291) hypothetical protein MLBr_00213
M. marinum MMMAR_5125mesJ5e-9266.10% (292) cell cycle protein MesJ
M. avium 104MAV_0531tilS3e-9667.25% (287) tRNA(Ile)-lysidine synthetase
M. smegmatis MC2 155MSMEG_6111tilS6e-9061.49% (296) tRNA(Ile)-lysidine synthetase
M. thermoresistible (build 8)TH_1410mesJ9e-8762.54% (291) POSSIBLE CELL CYCLE PROTEIN MESJ
M. ulcerans Agy99MUL_4201mesJ2e-9165.75% (292) cell cycle protein MesJ
M. vanbaalenii PYR-1Mvan_5378-3e-9266.44% (292) tRNA(Ile)-lysidine synthetase

CLUSTAL 2.0.9 multiple sequence alignment


Mb3649c|M.bovis_AF2122/97           MDRQSAVAQLRAAAEQFARVHLDACDRWSVGLSGGPDSLALTAVAAR-LW
Rv3625c|M.tuberculosis_H37Rv        MDRQSAVAQLRAAAEQFARVHLDACDRWSVGLSGGPDSLALTAVAAR-LW
MMAR_5125|M.marinum_M               MDRQGAVAQLRRAVEKFASTHLDATDRWSIGLSGGPDSLALTAVAAR-LR
MUL_4201|M.ulcerans_Agy99           MDRQGAVAQLRRAVENFASTHLDATDRWSIGLSGGPDSLALTAVAAR-LR
MLBr_00213|M.leprae_Br4923          MDRQGAVGQLRRTVEEFAGTYCDIDDQWCVALSGGSDSLALTAVAAQ-LR
MAV_0531|M.avium_104                MDRPGALDRLRTAVEAFSTAHLGAVERWCVALSGGPDSLALTAVAAR-LR
MSMEG_6111|M.smegmatis_MC2_155      MDRSRAVATLRRTVADFA-AQVDG-ERWCVALSGGPDSLALTAVAAA-ER
Mflv_1411|M.gilvum_PYR-GCK          MDRSGPVVELRTALVDFARTHRFPP-PWCVALSGGPDSLALTAVAAT-LH
Mvan_5378|M.vanbaalenii_PYR-1       MDRPGAVAELRTAVAGFVRDHAAASGPWCVALSGGADSLALTAVAAA-LR
TH_1410|M.thermoresistible__bu      MDRPGAVAALRSALAAFERAWAGADDRWCVALSGGADSLALTAVAAE-LK
MAB_0521|M.abscessus_ATCC_1997      ------------------------MTEVAVALSGGADSLALAAAAVARAW
                                                                .:.****.*****:*.*.    

Mb3649c|M.bovis_AF2122/97           PTTALIVDHGLQPGSATVAETARIQAISLGCVDARVLCVQVG----AAGG
Rv3625c|M.tuberculosis_H37Rv        PTTALIVDHGLQPGSATVAETARIQAISLGCVDARVLCVQVG----AAGG
MMAR_5125|M.marinum_M               PTTALIVDHGLQPDSAAVSETARAQAVSLGCVAARVLRVQVGNPAGAGGG
MUL_4201|M.ulcerans_Agy99           PTTALIVDHGLQPDSAAVSETARAQAVSLGCVTARVLRVQVGNPAGAGGG
MLBr_00213|M.leprae_Br4923          STTAFIVDHGLQSDSAAVAETARKQAISLGCVDAQVLCVQIDPPFGPKGG
MAV_0531|M.avium_104                PTTAVIVDHGLQPDSAAVAQTARAQAIALGCVAAQVISVHVD----GEGG
MSMEG_6111|M.smegmatis_MC2_155      PTTALIVDHGLQTGSRAVAETARAQALSVGCVGAEIIPVVVG----RSGG
Mflv_1411|M.gilvum_PYR-GCK          PTTALIVDHRLQPGSADVAAAAREQALALGCVAAQVLPVDVG----SPGG
Mvan_5378|M.vanbaalenii_PYR-1       PTTALIVDHGLQPGSARVAATARDQAMALGCVGAQVLCVEVG----VGGG
TH_1410|M.thermoresistible__bu      PTTALIVDHQLQPGSAEVAQTARRQALQLGCVAARILRVQVG----TAGG
MAB_0521|M.abscessus_ATCC_1997      SVTALIVDHGLQQDSAQVAARARSQALALGCSDAVVLSVTVD----GVGG
                                    ..**.**** ** .*  *:  ** **: :**  * :: * :.      **

Mb3649c|M.bovis_AF2122/97           REAAARSARYSALEEHRDG-PVLLAHTLDDQAETVLLGLGRGSGARSIAG
Rv3625c|M.tuberculosis_H37Rv        REAAARSARYSALEEHRDG-PVLLAHTLDDQAETVLLGLGRGSGARSIAG
MMAR_5125|M.marinum_M               LEAAARTARYGALDAHRDG-PVLLAHTLDDQAETVLLGLGRGSGARSIAG
MUL_4201|M.ulcerans_Agy99           LEAAARTARYGALDAHRDG-PVLLAHTLDDQAETVLLGLGRGSGARSIAG
MLBr_00213|M.leprae_Br4923          LEAAARAARYAVLGANRNG-PVLLAHTLDDQAETVLLGLGRGSGARSIAG
MAV_0531|M.avium_104                PEAAARRARYAALAAHRDG-PVLLGHTLDDQAETVLLGLGRGSGVRSIAG
MSMEG_6111|M.smegmatis_MC2_155      PEAAARKARYTALQAARDGAPVLLGHTLDDQAETVLLGLARGSGPRSIAG
Mflv_1411|M.gilvum_PYR-GCK          PEAAARTARYRALDDARDGKPVLLGHTLDDQAETVLLGLGRGSGPRSIAG
Mvan_5378|M.vanbaalenii_PYR-1       PEAAARAARYRALEEARRGAPVLLAHTLDDQAETVLLGLGRGSGARSIAG
TH_1410|M.thermoresistible__bu      PEAAARTARYEALSTARGEAPVLLGHTLDDQAETVLLGLGRGSGPRSIAG
MAB_0521|M.abscessus_ATCC_1997      LEAAARSARYAALEQARDGRPVLLAHTLDDQAETVLLGLGRGSGARSIAG
                                     ***** *** .*   *   ****.**************.**** *****

Mb3649c|M.bovis_AF2122/97           MRPYDPPWCRPLLGVRRSVTHAACRELGLTAWQDPHNTDRRFTRTRLRTE
Rv3625c|M.tuberculosis_H37Rv        MRPYDPPWCRPLLGVRRSVTHAACRELGLTAWQDPHNTDRRFTRTRLRTE
MMAR_5125|M.marinum_M               MRPHDPPWCRPLLGVRRGVTHDACRELGLTAWQDPHNSDRRFTRTRLRAE
MUL_4201|M.ulcerans_Agy99           MRPHDPPWCRPLLGVRRGVTHDACRELGLTAWQDPHNSDRRFTRTRLRAE
MLBr_00213|M.leprae_Br4923          MRPHDPPWCRPLLGVRRSVPRAACHELGLNAWQDPHNTDCRYTRTRLRLE
MAV_0531|M.avium_104                MRPHDPPWCRPLLGQRRAVTHAACAELGLTAWQDPHNSDRRFTRARLRAE
MSMEG_6111|M.smegmatis_MC2_155      MRPHDPPWHRPLLGIRRTVTHAACEELGLKPWHDPHNFEPRFTRTRLRLD
Mflv_1411|M.gilvum_PYR-GCK          MRPYDLPWGRPLLGVRRDTTHRACAELGLNPWQDPHNLDPRYTRVRLRTE
Mvan_5378|M.vanbaalenii_PYR-1       MRPSDPPWCRPLLGVRRAVTRLACAELGLTPWQDPHNTDRRFTRVRLRTE
TH_1410|M.thermoresistible__bu      MRPHDPPWYRPLLGVRRSVTVAACAELGLTPWQDPHNADPRFTRSRLRTE
MAB_0521|M.abscessus_ATCC_1997      MRPWDDPWGRPFLDRRRTETRSYCDELAITAWEDPHNVDSRFVRVRLRHE
                                    *** * ** **:*. **  .   * **.:..*.**** : *:.* *** :

Mb3649c|M.bovis_AF2122/97           VLPLLEDVLGGGVAEALARTATALREDTDLIDTIAAQALPGAAVAGSRG-
Rv3625c|M.tuberculosis_H37Rv        VLPLLEDVLGGGVAEALARTATALREDTDLIDTIAAQALPGAAVAGSRG-
MMAR_5125|M.marinum_M               VLPLLEEVLGGGVAAALARTATALRADTELLDAIAAEALPTAVVDSG---
MUL_4201|M.ulcerans_Agy99           VLPLLEEVLGGGVAAALARTATALRADTELLDAIAAEALPTAVVDFG---
MLBr_00213|M.leprae_Br4923          VLPLLEDVLGGGVVEALARTATALREDTELIDTFAAQALPNICAGSG---
MAV_0531|M.avium_104                VLPLLEEVLGGGVAEALARTATALREDNEVLDALAERALPAAQAGAG---
MSMEG_6111|M.smegmatis_MC2_155      VMPLLEEVLGGGVAEALARTATALREDTETLDEIARQALETSQTSARTP-
Mflv_1411|M.gilvum_PYR-GCK          VLPLLEDVLGGGVAEALARTAAALREDTDVLDALAA---EAVAPGDAD--
Mvan_5378|M.vanbaalenii_PYR-1       VLPLLEDVLGGGVAEALARTATALREDTDALDGIAA---RIVTVPGAD--
TH_1410|M.thermoresistible__bu      VMPLLEEVLGGGVAEALARTAAALREDTDALDELAARELRRVVVGGEEGG
MAB_0521|M.abscessus_ATCC_1997      VLPLLEEVLGGGVAEALARTALSLQDDGDALDAQARAAFPGAQG------
                                    *:****:******. ****** :*: * : :*  *               

Mb3649c|M.bovis_AF2122/97           -----QELSTSALTALPDAVRRRVIRGWLLAGGATGLTDRQIRGVDRLVT
Rv3625c|M.tuberculosis_H37Rv        -----QELSTSALTALPDAVRRRVIRGWLLAGGATGLTDRQIRGVDRLVT
MMAR_5125|M.marinum_M               -------LDTSVLATLPDPVRRRVIRSWLLAGGAIGLTDKQIRGVDALVT
MUL_4201|M.ulcerans_Agy99           -------LDTSVLATLPDPVRRRVIRSWLLAGGAIGLTDKQIRGVDALVT
MLBr_00213|M.leprae_Br4923          -------LHARALAALPDAVRRRVIRGWLLNGGATGLTDKQIRGVDTLVT
MAV_0531|M.avium_104                -------LQVAALAGLDAPVRRRVIRAWLLAGGATGLTDKQIRGVDNLIT
MSMEG_6111|M.smegmatis_MC2_155      -----PGLDTEVLAGLPGAVRRRVIRAWLLTNGGTDLTDVQIRGVDRLVT
Mflv_1411|M.gilvum_PYR-GCK          -------LDVTALADLPTALRRRAVRGWLLAAGARDLTDKHLRAVDALIT
Mvan_5378|M.vanbaalenii_PYR-1       -------LDTAVLTPLPAAVRRRVIRGWLLGGGANGLTDKQIRAVDDLVV
TH_1410|M.thermoresistible__bu      ETGAATGLDARALERLPTAIRRRVIRVWLLDGGAANLSDHQIRAVDTLVT
MAB_0521|M.abscessus_ATCC_1997      -------LAISDLRGLTPAVRRRVIRLWLLAGGAQDLNDNQIRAVDALVT
                                           *    *  *  .:***.:* ***  *. .*.* ::*.** *:.

Mb3649c|M.bovis_AF2122/97           AWRGQGGVAVGSTLRGQRLVAGRRDGVLVLRREPV---------------
Rv3625c|M.tuberculosis_H37Rv        AWRGQGGVAVGSTLRGQRLVAGRRDGVLVLRREPV---------------
MMAR_5125|M.marinum_M               AWRGQGGVAVGSNLKARRLVAGRGGGLLTLRSEPI---------------
MUL_4201|M.ulcerans_Agy99           AWRGQGGVAFGSNLKARRLVAGRGGGLLTLRSEPI---------------
MLBr_00213|M.leprae_Br4923          AWRGQGGVAVGSTLRGQRLIASRYDGVLTLHCAPV---------------
MAV_0531|M.avium_104                AWRGQGGVAVGSSQPGERLFAGRRDGVLTLWREPVR--------------
MSMEG_6111|M.smegmatis_MC2_155      DWRGQGGVAVGSNLSRQRLFVGRRHGELVLYTEPV---------------
Mflv_1411|M.gilvum_PYR-GCK          DWHGQGGVAVPGGLTRERLFVARNRNRLGMYREPVAQ--------RQG--
Mvan_5378|M.vanbaalenii_PYR-1       DWHGQGGVAVPGGLARERLFAGRRKDVLTLYREPVAE--------RQR--
TH_1410|M.thermoresistible__bu      GWRGQGGVAVGSPLRGXXXATARACGVSRSGTPALTSGTCRRCRLRRGVS
MAB_0521|M.abscessus_ATCC_1997      QWRGQGGVAVGADLRYQRLVASRSGEQLVLSVHDVAR-------------
                                     *:******. .        ..*           :               

Mb3649c|M.bovis_AF2122/97           -
Rv3625c|M.tuberculosis_H37Rv        -
MMAR_5125|M.marinum_M               -
MUL_4201|M.ulcerans_Agy99           -
MLBr_00213|M.leprae_Br4923          -
MAV_0531|M.avium_104                -
MSMEG_6111|M.smegmatis_MC2_155      -
Mflv_1411|M.gilvum_PYR-GCK          -
Mvan_5378|M.vanbaalenii_PYR-1       -
TH_1410|M.thermoresistible__bu      G
MAB_0521|M.abscessus_ATCC_1997      -