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M. smegmatis MC2 155 MSMEG_6021 (xylA)

annotation: xylose isomerase
coordinates: 6086090 - 6087313
length: 407

TVLESNVSTTEPLTPKREDRFSFGLWTIGWNGNDPFGVATRPALDVVEAVEKLAELGAYGLTFHDDDLFA
FGSSDTERRRMVDRLTSALSANGMVVPMVTTNLFTQPVFKDGGFTSNDRTVRRFALRKVLRNIDLAIELG
AETFVLWGGREGSEYDSAKDVQAALARYREAMDLLCQYVIDQGSGLRFAIEPKPNEPRGDILLPTVGHAL
AFIDTLARPEMVGVNPETGHEQMSGLNFMHGIAQALYSGKLFHIDLNGQRGIKFDQDLVFGHGDLANAFA
LVDLLEHGGPDGTPAYEGPRHFDYKPSRTEDIDGVWASAAANMRMYLLLKQRAEAFRADPAVREAMAAAK
VAELRQPTLAPGETYHDLLADRSAFEEFDSEAYFGGKGCGFVALQQLAIEHLMGAR*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_6021xylA-100% (407)xylose isomerase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97-----
M. gilvum PYR-GCK-----
M. tuberculosis H37Rv-----
M. leprae Br4923-----
M. abscessus ATCC 19977-----
M. marinum MMMAR_2510-2e-0827.62% (210) sugar phosphate isomerase/epimerase
M. avium 104-----
M. thermoresistible (build 8)-----
M. ulcerans Agy99MUL_1694-2e-0830.41% (171) sugar phosphate isomerases/epimerases
M. vanbaalenii PYR-1Mvan_5294-0.086.73% (407) xylose isomerase

CLUSTAL 2.0.9 multiple sequence alignment


MSMEG_6021|M.smegmatis_MC2_155      -----MTVLESNVSTTEPLTPKREDRFSFGLWTIGWNGNDPFG-------
Mvan_5294|M.vanbaalenii_PYR-1       -----MTVLESSRPVPDALSPRREDKFSFGLWTVGWPGVDPFG-------
MMAR_2510|M.marinum_M               MHVGYNTNSLADHPIAEALALIAEEGYSAVALTVGYPHVRPMDSDLGAQL
MUL_1694|M.ulcerans_Agy99           MHVGYNTNSLADHPIAEALALISEEGYSAVALTVGYPHVRPMDSDLGAQL
                                          *   :. . .:.*:   *: :*    *:*:    *:.       

MSMEG_6021|M.smegmatis_MC2_155      ------------------------------------VATRPALDVVE-AV
Mvan_5294|M.vanbaalenii_PYR-1       ------------------------------------VATRPALDAIE-AV
MMAR_2510|M.marinum_M               DALGCLLDTYGLTVAIETGARYLLDPHNKHKPSLVDVAAQPRIEFLQRAI
MUL_1694|M.ulcerans_Agy99           DALGCLLDTYGLTVAIETDARYLLDPHNKHKPSPVDVAAQPRIEFLQRAI
                                                                        **::* :: :: *:

MSMEG_6021|M.smegmatis_MC2_155      EKLAELGAYGLTFHDDDLFAFGSSDTERRRMVDRLTSALSANGMVVPMVT
Mvan_5294|M.vanbaalenii_PYR-1       DRLAALGAYGLTFHDDDLFAFGSSDGERRRAIDRLTSALSANGLVVPMVT
MMAR_2510|M.marinum_M               DIAAELGATCVSLWSGYSVSYSDAATTRDLLLSRLSRLVEYADRKSVILG
MUL_1694|M.ulcerans_Agy99           DIAAELGATCVSLWSGYSVSYSDAATTRDLLLSRLSRLVEYADRKSVMLG
                                    :  * ***  ::: ..  .::..:   *   :.**:  :.  .    :: 

MSMEG_6021|M.smegmatis_MC2_155      TN----LFTQPVFKDGGFTSNDRTVRRFALRKVLRNIDLAIELGAETFVL
Mvan_5294|M.vanbaalenii_PYR-1       TN----LFTQPVFKDGGFTSNDRAVRRFALRKVLRNLDLAAELGAQTFVM
MMAR_2510|M.marinum_M               FEPEPGMFVETVQQALGLCSELGDPARLGITLDVGHCVMTEPAGAEAAIA
MUL_1694|M.ulcerans_Agy99           FEPEPGMFVETVQQALGLCSELGDPARLGITLDVGHCVMTEPAGAEAAIA
                                     :    :*.:.* :  *: *:     *:.:   : :  ::   **:: : 

MSMEG_6021|M.smegmatis_MC2_155      WGGREGSEYDSAKDVQAALARYREAMDLLCQYVIDQGSGLR-FAIEPKPN
Mvan_5294|M.vanbaalenii_PYR-1       WGGREGGEYDSAKDVQAALERYREALDVLCQYVIDQGSGIR-FAIEPKPN
MMAR_2510|M.marinum_M               ELGDKLVNVHLDDMTPLKHEHLEFGYGALDLGAVMDALQVAGFAGVASVE
MUL_1694|M.ulcerans_Agy99           ELGDKLVNVHLDDMTPLKHEHLEFGYGALDLGAVMDALQVAGFAGVASVE
                                      * :  : .  . .     : . . . *   .: :.  :  **  .. :

MSMEG_6021|M.smegmatis_MC2_155      EPRGDILLPTVGHALAFIDTLARPEMVGVNPETGHEQMSGLNFMHGIAQA
Mvan_5294|M.vanbaalenii_PYR-1       EPRGDILLPTVGHALAFIETLAHPEMVGVNPETGHEQMSGLNFTHGIAQA
MMAR_2510|M.marinum_M               LPRHAHDAPKV--ARRSMNSIKLAQLPLQVRTWIAEAAAVLRRDPEKVLE
MUL_1694|M.ulcerans_Agy99           LPRHAHDAPKV--ARRSMNSIKLPQLPLQVRTWIAEAAAVLRRDPEKVLE
                                     **     *.*  *   ::::  .::         *  : *.     .  

MSMEG_6021|M.smegmatis_MC2_155      LYSGKLFHIDLNGQRGIKFDQ-----DLVFGHGDLANAFALVDLLEHGGP
Mvan_5294|M.vanbaalenii_PYR-1       LYSGKLFHIDLNGQRGIKFDQ-----DLVFGHGDLVNAFSLVDLLEHGGP
MMAR_2510|M.marinum_M               LFSGAQRQMPASSDEATVLARGRLVATLVAETPDVTAGPLIDKLYRWGDS
MUL_1694|M.ulcerans_Agy99           LFSGAQCQMPASSDEATVLARGRLVATLVAETPDVTAGPLIDKLYRWGDS
                                    *:**   ::  ..:..  : :      **    *:. .  : .* . *..

MSMEG_6021|M.smegmatis_MC2_155      DGTP-AYEGPRHFDYKPSRTEDIDGVWASAAANMR-------MYLLLKQR
Mvan_5294|M.vanbaalenii_PYR-1       DGGP-AYDGPRHFDYKPSRTEDAEGVWASAAANMR-------MYLLLRQR
MMAR_2510|M.marinum_M               DERLGVFCGLETAASEETLGPDATRVGVGLAEDALRCNDPRLVAAALGGF
MUL_1694|M.ulcerans_Agy99           DERLGVFCGLETAASEETLGPDATRVGVGLAEDALRCNDPRLVAAALGGF
                                    *    .: * .    : :   *   * .. * :         :   *   

MSMEG_6021|M.smegmatis_MC2_155      AEAFRADPAVREAMAAAKVAELRQPTLAPGETYHDLLADRSAFEEFDSEA
Mvan_5294|M.vanbaalenii_PYR-1       AAAFRADPDVREAMVAAKVAELRKPTLAAGETYADLLNDRSAYEEFDTGA
MMAR_2510|M.marinum_M               GARFLAQHRWRDGVMKLVFMGVPLRGVSGLRSRADTELGRMATDYASERA
MUL_1694|M.ulcerans_Agy99           GARFLAQHRWRDGVMKLVFMGVPLRGVSSLCSRADTELGRMATDYASERA
                                    .  * *:   *:.:    .  :    ::   :  *   .* * :  .  *

MSMEG_6021|M.smegmatis_MC2_155      YFGGKG-CGFVALQQLAIEHLMGAR
Mvan_5294|M.vanbaalenii_PYR-1       YFGGKG-CGFVALHQLAVEHLMGAR
MMAR_2510|M.marinum_M               AAGRMIPADAQLLQRLCATEAEALK
MUL_1694|M.ulcerans_Agy99           AAGRMIPADAQLLQRLCATEAEALK
                                      *    ..   *::*.  .  . :