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ADGRGNAGAPLSHLPLGNMDPVSGDNLRVSDAERTQVRHALERAVGAGMLTLDEFTERVDIALAARTRGE LNAVLADLPDPTAPMAPTVQRRPEELRSWMSTIERRGQWTVAPTLRLVTRMCNTTLDFTSAVLPGRVVHI EIDDYCSTTTLIVPGNATADLNGVHPVAGNATLKVRSSPPSEHLHLVVRGRVRMGTVTVRHSYTRWLRRL SGSR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_5843 | - | - | 100% (215) | hypothetical protein MSMEG_5843 |
| M. smegmatis MC2 155 | MSMEG_2585 | - | 5e-26 | 36.57% (175) | hypothetical protein MSMEG_2585 |
| M. smegmatis MC2 155 | MSMEG_5505 | - | 4e-12 | 28.42% (183) | hypothetical protein MSMEG_5505 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2887c | - | 6e-25 | 34.41% (186) | hypothetical protein Mb2887c |
| M. gilvum PYR-GCK | Mflv_1614 | - | 2e-57 | 61.62% (185) | hypothetical protein Mflv_1614 |
| M. tuberculosis H37Rv | Rv2862c | - | 8e-25 | 34.41% (186) | hypothetical protein Rv2862c |
| M. leprae Br4923 | MLBr_00169 | - | 4e-10 | 26.37% (182) | hypothetical protein MLBr_00169 |
| M. abscessus ATCC 19977 | MAB_1068c | - | 1e-12 | 29.19% (185) | hypothetical protein MAB_1068c |
| M. marinum M | MMAR_1841 | - | 2e-25 | 36.07% (183) | hypothetical protein MMAR_1841 |
| M. avium 104 | MAV_1086 | - | 3e-11 | 28.11% (185) | hypothetical protein MAV_1086 |
| M. thermoresistible (build 8) | TH_1268 | - | 2e-53 | 57.45% (188) | conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_2090 | - | 3e-25 | 36.07% (183) | hypothetical protein MUL_2090 |
| M. vanbaalenii PYR-1 | Mvan_5140 | - | 1e-56 | 59.46% (185) | hypothetical protein Mvan_5140 |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_5843|M.smegmatis_MC2_155 ------------MADGRGNAGAPLSHLPLGNMDPVSGDNLRVSDAERTQV
TH_1268|M.thermoresistible__bu ------------MDSGHHDA------------------HLRASDADRAAV
Mflv_1614|M.gilvum_PYR-GCK ------------MDSGQPDI--------------------RASDADRAAV
Mvan_5140|M.vanbaalenii_PYR-1 -----------MMDFEHPDI--------------------RASDADRAAV
MMAR_1841|M.marinum_M MIAVSEGHQEKAMTDSGAEMVA-----------------LRVSDADRNGT
MUL_2090|M.ulcerans_Agy99 ------------MTDSGAEMVA-----------------LRVSDADRNGT
Mb2887c|M.bovis_AF2122/97 ------------MTETGGDMVA-----------------LRVSDADPNGT
Rv2862c|M.tuberculosis_H37Rv ------------MTETGGDMVA-----------------LRVSDADRNGT
MLBr_00169|M.leprae_Br4923 ------------MSNSAQRDAKGARD-----------EPLRAADTDRIQI
MAV_1086|M.avium_104 -----------MMSNSTQRDAEDTRD-----------EPSRAADTDRIQI
MAB_1068c|M.abscessus_ATCC_199 ------------MSNLPERVTASMR----------------AADVDRMRV
* .:*.:
MSMEG_5843|M.smegmatis_MC2_155 RHALERAVGAGMLTLDEFTERVDIALAARTRGELNAVLADLPDPTAP-MA
TH_1268|M.thermoresistible__bu RQLLERAVGEGMLTLDEYTERVDVALAARTRGELDKVLADLPMARRPDLA
Mflv_1614|M.gilvum_PYR-GCK TQILEHAVGQGMLTLDEYTERIDVVLGARTRRELDTVIADLPHIRRA--P
Mvan_5140|M.vanbaalenii_PYR-1 TRILENAVGQGMLTLDEYSERVDVVLAARTRRELDTVIADLPHIRHR--P
MMAR_1841|M.marinum_M MRRLHNAVALGLIDINEFEQRSSRVSFARTQNELDGLVCDLPGPGAIVTS
MUL_2090|M.ulcerans_Agy99 MRRLHNAVTLGLIDINEFEQRSSRVSFARTQNELDGLVCDLPGPGAIVTS
Mb2887c|M.bovis_AF2122/97 MRRLHNAVALGLINIDEFEQRSSRVSFARTRSELDGLVGDLPRPGAIVTS
Rv2862c|M.tuberculosis_H37Rv MRRLHNAVALGLINIDEFEQRSSRVSFACTRSELDGLVGDLPRPGAIVTS
MLBr_00169|M.leprae_Br4923 AQLLAYAAEQGRLELKDYEDRLAKAYAATTYQELEQLRDDLPGSQVSARR
MAV_1086|M.avium_104 AQLLAYAAEQGRLQLNDYEDRLTRAYAAKTYEELDQLRADLPGAPISPRR
MAB_1068c|M.abscessus_ATCC_199 AQLLSDAAAQGRLELSEFEQRLAKVYSANTYGELDQLSADLPDVATSPVR
: * *. * : :.:: :* . * * **: : ***
MSMEG_5843|M.smegmatis_MC2_155 PTVQR--RPEELRSWMSTIERRGQWTVAPTLRLVTRMCNTTLDFTSAVLP
TH_1268|M.thermoresistible__bu QSTQ----PLLLRGRFSTLSRKGEWSVPARVVVDTRMCDTTLDFTVAMLR
Mflv_1614|M.gilvum_PYR-GCK APAP----PEVLRTWMSGISRKGPWTVPPRLRLVTRMCSTTLDFTSAVLH
Mvan_5140|M.vanbaalenii_PYR-1 APAP----PEVLRGWMSSMSRRGQWTVPARLRLVTRMCSTTLDFTSAVLQ
MMAR_1841|M.marinum_M AADR-----VELRGWAGSLKRHGEWMVPTRLALVRRLGSIELDLTKARFA
MUL_2090|M.ulcerans_Agy99 AADR-----VELRGWAGSLKRHGEWMVPTRLALVRRLGSIELDLTKARFA
Mb2887c|M.bovis_AF2122/97 AADR-----VELRGWAGSLKRHGEWIVPTRLALVRRLGSIELDLVKARFA
Rv2862c|M.tuberculosis_H37Rv AADR-----VELRGWAGSLKRHGEWIVPTRLALVRRLGSIELDLVKARFA
MLBr_00169|M.leprae_Br4923 GGNPNPAPSTLLLALMSGFERRGRWNVPRKLTTFSLWGSGVLDLRYADFT
MAV_1086|M.avium_104 GGKPNPAPSTLLLALLSGFERRGRWNVPKKLTTFTLWGSGVVDLRYADFT
MAB_1068c|M.abscessus_ATCC_199 GQGSKPAPSTVLMAIMSGFERRGRWNVPGKLTSFALWGGGVLDLRYADFT
* . :.*:* * *. : . :*: * :
MSMEG_5843|M.smegmatis_MC2_155 GRVVHIEIDDYCSTTTLIVPGNATADLNGVHPVAGNATLKVRSSPPSEHL
TH_1268|M.thermoresistible__bu SPVVHVDIDDYLSTTTLILPDGATGDVNAVETFASTVNGRVPAAPPSQRL
Mflv_1614|M.gilvum_PYR-GCK NPVVHIDIDDYFSATELILPDGATADLNGVVQVGASTTVKVTSSPPSRAL
Mvan_5140|M.vanbaalenii_PYR-1 SPVVHIDIDDYFGSTELVLPDGATADLNGVGNVASSTTVKVTASPPSQRL
MMAR_1841|M.marinum_M GPVVVIELDMRFGSLELRLPEGASASIDDVEVYVGSASDRRKDAPGEGTP
MUL_2090|M.ulcerans_Agy99 GPVVVIELDMRFGSLELRLPEGASASIDDVEVYVGSASDRRKDAPGEGTP
Mb2887c|M.bovis_AF2122/97 GPVVVIELDMMFGSLEVRLPNGASASIDDVEVYVGSASDRRKDAPAEGTP
Rv2862c|M.tuberculosis_H37Rv GPVVVIELDMMFGSLEVRLPNGASASIDDVEVYVGSASDRRKDAPAEGTP
MLBr_00169|M.leprae_Br4923 STEVELHAYSVMGVQTILLPPEVNVEISGHGVMG-SFDRQVRGQGTPGAP
MAV_1086|M.avium_104 STEVDIHAMSIMGVQSILLPPEVNVEVHGRGVMG-NFDRDVPGQGTPGAP
MAB_1068c|M.abscessus_ATCC_199 SNEVEIRSFSIMGGQTILLPPEVNVDVKGVAVMG-GFDHSASGNGVQGAP
. * : . : :* .. .:
MSMEG_5843|M.smegmatis_MC2_155 HLVVRGRVRMGTVTVRHSYTRWLRRLSGSR--
TH_1268|M.thermoresistible__bu HLVIRGRVRLATVTVRYSFGAAWRRFTGRSEP
Mflv_1614|M.gilvum_PYR-GCK HVVVTGRVRFGSVTARHPFGTALKRLLK----
Mvan_5140|M.vanbaalenii_PYR-1 HVVVAGKMRFGSLTARHPFGTTLKRLLS----
MMAR_1841|M.marinum_M HVVVTGQVVCGSVVIRGPRRALLRRHQV----
MUL_2090|M.ulcerans_Agy99 HVVVTGQVVCGSVVIRGPRRALLRRHQV----
Mb2887c|M.bovis_AF2122/97 HVVLTGRMVCGSVVIKGPRRALLRRHRG----
Rv2862c|M.tuberculosis_H37Rv HVVLTGRMVCGSVVIKGPRRALLRRHRG----
MLBr_00169|M.leprae_Br4923 TVKIRGFSLWGGVGIKRKARRPRR--------
MAV_1086|M.avium_104 TVHIRGFSLWGGVGIRRKARRPRP--------
MAB_1068c|M.abscessus_ATCC_199 HVTVKGFSLWGGVNVKRKRRKRRESLEER---
: : * . : :