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MTTGMGLRGDRLHRYVTAFCPHCHAEAPERPLADVQRLAAMLIERDGRIWLERGCPTHGLVRTLYDEDPK ILSYLEEWTAPTKAHTPDVAGNFDPVPSAYLRGLPEMQTQHTCILLEDISEACNLRCPTCFTDSSPDLRN VVPVAEVLANIDQRLARENGRIDVLMLSGGEPTLHPQLPTLLAELVKRPITRILVNSNGVRIANDDALLD LLTLHRERVEVYLQYDGLSAETHRHHRGGDLGRLKQQALQRLSEREIFTTLVMTATLGVNDHEIGAMVQL ALDTPYVGGLTIQPQFGSGRSGAIDPMERLTHTGVLKRMGPQTDGAVTWRDLTALPCSHPHCCSVGYLVR DDSDRWRSLVSLIGAESLKDKLGLVANRIADTEIPRELRLAVQESLLGLLSEQSSLSHPEIGDVWRNICE NCDLGMSTLLTLASSTLPGRRRKIRRLLGERVVRLTVKPFMDMSTMIEERLIQCCVHVGTRSTEQHQCAP FCAVQAWPALSRQRLSLASQATMPALPLIEIR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_5410 | - | - | 100% (522) | radical SAM domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3756 | - | 3e-47 | 29.84% (496) | transferase |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. tuberculosis H37Rv | Rv3729 | - | 6e-47 | 29.64% (496) | transferase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | MAV_4478 | - | 5e-06 | 24.47% (188) | radical SAM domain-containing protein |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_5883 | - | 7e-07 | 31.36% (118) | radical SAM domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3756|M.bovis_AF2122/97 ----------MFVEYTKSICPVCKVVVD-----------AQVNIRHDKVY
Rv3729|M.tuberculosis_H37Rv ----------MFVEYTKSICPVCKVVVD-----------AQVNIRHDKVY
MSMEG_5410|M.smegmatis_MC2_155 MTTGMGLRGDRLHRYVTAFCPHCHAEAPERPLADVQRLAAMLIERDGRIW
MAV_4478|M.avium_104 --------------------------------------------------
Mvan_5883|M.vanbaalenii_PYR-1 ---------MVILDLMRLMATLADGAVG---------EIAVASVAERETA
Mb3756|M.bovis_AF2122/97 LRKRCREHGSFEALVYGDAQMYLESARFNKPGTFPLRFQTEVRDGCPSDC
Rv3729|M.tuberculosis_H37Rv LRKRCREHGSFEALVYGDAQMYLESARFNKPGTFPLRFQTEVRDGCPSDC
MSMEG_5410|M.smegmatis_MC2_155 LERGCPTHGLVRTLYDEDPKILSYLEEWTAPTKAHTPDVAGNFDPVPSAY
MAV_4478|M.avium_104 MTTAAPVPRLIEQFEHG---------------------------------
Mvan_5883|M.vanbaalenii_PYR-1 EKWCARSGNTVVQADLDETGAGTLTVRRGRPPDPLLVLGPE---------
. .
Mb3756|M.bovis_AF2122/97 G--LCPDHKQHACLGLIEVNTHCNLDCPICFADSGHQPDGYAITAAQCER
Rv3729|M.tuberculosis_H37Rv G--LCPDHKQHACLGLIEVNTHCNLDCPICFADSGHQPDGYAITAAQCER
MSMEG_5410|M.smegmatis_MC2_155 LRGLPEMQTQHTCILLEDISEACNLRCPTCFTDSSPDLRNVVPVAEVLAN
MAV_4478|M.avium_104 --------LDAPICLTWELTYACNLACVHCLSSSGKR-DPRELSTRQCMD
Mvan_5883|M.vanbaalenii_PYR-1 --------RMPGARLWMYTNFHCNLACDYCCVESSPQAPRRELGADRIAR
. *** * * .*. :
Mb3756|M.bovis_AF2122/97 MLDTLVAAEGEPEVVMFSGGEPTIHKQLLEFVDAAQARPVKTIIINTNGI
Rv3729|M.tuberculosis_H37Rv MLDTLVAAEGEPEVVMFSGGEPTIHKQLLEFVDAAQARPVKTVIINTNGI
MSMEG_5410|M.smegmatis_MC2_155 IDQRLARENGRIDVLMLSGGEPTLHPQLPTLLAELVKRPITRILVNSNGV
MAV_4478|M.avium_104 IIDELER--MQVFYVNIGGGEPTVRPDFWELVDYATAHHVG-VKFSTNGV
Mvan_5883|M.vanbaalenii_PYR-1 LAR--EAADWGVREVFLTGGEPFLLSDIGTIVRSCAALLPTTVLTNGMVF
: : : **** : :: :: : . .
Mb3756|M.bovis_AF2122/97 RLASDRRFVDQLATRNRPGHPVHIYLQFDGLDEATHRRIRGHDLRDVKQR
Rv3729|M.tuberculosis_H37Rv RLASDRRFVDQLATRNRPGHPVHIYLQFDGLDEATHRRIRGHDLRDVKQR
MSMEG_5410|M.smegmatis_MC2_155 RIANDDALLDLLTLHR---ERVEVYLQYDGLSAETHRHHRGGDLGRLKQQ
MAV_4478|M.avium_104 RITP------EVAARLAASDYVDVQISLDGATAEVNDAVRGPGSFDMAVR
Mvan_5883|M.vanbaalenii_PYR-1 RGRG------LRELDAIPRDNVALQISLDSATSELHDSHRGHGSWARAVE
* . * : :. *. : ** . .
Mb3756|M.bovis_AF2122/97 ALDNCAAAGLTVSLVAAVERGLNEHELGAVIRHG-MAQPGVQSVVFQPVT
Rv3729|M.tuberculosis_H37Rv ALDNCAAAGLTVSLVAAVERGLNEHELGAVIRHG-MAQPGVQPVVFQPVT
MSMEG_5410|M.smegmatis_MC2_155 ALQRLSEREIFTTLVMTATLGVNDHEIGAMVQLA-LDTPYVGGLTIQPQF
MAV_4478|M.avium_104 ALQNLADAGFTQNGGAKISVVVTRHNVGQLDEFAALASRYGATLRITRLR
Mvan_5883|M.vanbaalenii_PYR-1 GIRVARGLGFRVRVAATVAAPVP----GELKAFH----------------
.: : : * :
Mb3756|M.bovis_AF2122/97 HAGRHVQFDPLTRLTNSDIIACITAQLPEWFRPGDFFPVPCCFPSCRSIT
Rv3729|M.tuberculosis_H37Rv HAGRHVQFDPLTRLTNSDIIACITAQLPEWFRPGDFFPVPCCFPSCRSIT
MSMEG_5410|M.smegmatis_MC2_155 GSGRSGAIDPMERLTHTGVLKRMGPQTDGAVTWRDLTALPCSHPHCCSVG
MAV_4478|M.avium_104 PSGR-----------GADVWDELHPTADQQVQLYDWLVAKGERVLTG---
Mvan_5883|M.vanbaalenii_PYR-1 -----------------DFLDELGIAQDDQVVR-----------------
.. : .
Mb3756|M.bovis_AF2122/97 YLLTDGEHVVPIPRLLNVEDYLDYVSNRVIPDLAIREALENLWSASAVPG
Rv3729|M.tuberculosis_H37Rv YLLTDGEHVVPIPRLLNVEDYLDYVSNRVIPDLAIREALENLWSASAVPG
MSMEG_5410|M.smegmatis_MC2_155 YLVRD-----------------DSDRWRSLVSLIGAESLKDKLGLVANRI
MAV_4478|M.avium_104 ------------------------DSFFHLAPLGQSGALAGLNMCGAGRV
Mvan_5883|M.vanbaalenii_PYR-1 ------------------------------PVAREGSAADGVQITRASLV
: . *
Mb3756|M.bovis_AF2122/97 TDTMTAQLQRATAALNCAEGCGINLPEALTHLTDRVFAIVIQDFQDPYTL
Rv3729|M.tuberculosis_H37Rv TDTMTAQLQRATAALNCAEGCGINLPEALTHLTDRVFAIVIQDFQDPYTL
MSMEG_5410|M.smegmatis_MC2_155 ADTEIPRELRLAVQESLLG-----LLSEQSSLSHPEIGDVWRNICENCDL
MAV_4478|M.avium_104 VCLIDPVGDVYACPFAIHDR-----FLAGNVLSDGGFDNVWKNAPLFREL
Mvan_5883|M.vanbaalenii_PYR-1 PEVAVTAEGVYWHPVAAIDD------------------------------
.
Mb3756|M.bovis_AF2122/97 NVKQLMKCCVQQITPDGRLIPFCAYNSVGYREQVREQLTGVPVPDIVPNA
Rv3729|M.tuberculosis_H37Rv NVKQLMKCCVQQITPDGRLIPFCAYNSVGYREQVREQLTGVPVPDIVPNA
MSMEG_5410|M.smegmatis_MC2_155 GMSTLLTLASSTLP--------------GRRRKIRRLLG-----------
MAV_4478|M.avium_104 REPQSAGACG----------------SCGHYDSCR---------------
Mvan_5883|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3756|M.bovis_AF2122/97 IPLAGLLADAPHGSKQANTGGSIARLAGPTRGAPMALPPQQIKACCADAY
Rv3729|M.tuberculosis_H37Rv IPLAGLLADAPHGSKQANTGGSIARLAGPTRGAPMALPPQQIKACCADAY
MSMEG_5410|M.smegmatis_MC2_155 --------------------ERVVRLTVKPFMDMSTMIEERLIQCCVHVG
MAV_4478|M.avium_104 --------------------GGCMAAKFFTGLPLDGPDPECVQGHSAAAL
Mvan_5883|M.vanbaalenii_PYR-1 ------------------------DALVTRQIEPLAPALDEIAHAFAELW
: : .
Mb3756|M.bovis_AF2122/97 SRDIVALLLGDSFHPGGATLTRRLADQLGLRSTGDPRRVADIAAGPGASA
Rv3729|M.tuberculosis_H37Rv SRDIVALLLGDSFHPGGATLTRRLADQLGLRSTGDPRRVADIAAGPGASA
MSMEG_5410|M.smegmatis_MC2_155 TRSTEQHQCAP---------------------------FCAVQAWPALSR
MAV_4478|M.avium_104 AGDREAPRPRAD--------------------------HSRGKRIRQPVP
Mvan_5883|M.vanbaalenii_PYR-1 ARKANAAQLFPCA-------------------------------------
: .
Mb3756|M.bovis_AF2122/97 RLLASDYGVAVDGVDISEINVKRAQAAVAQTGLTERVRFHLGDAESVPLP
Rv3729|M.tuberculosis_H37Rv RLLASDYGVAVDGVDISEINVKRAQAAVAQTGLTERVRFHLGDAESVPLP
MSMEG_5410|M.smegmatis_MC2_155 QRLSLASQATMPALPLIEIR------------------------------
MAV_4478|M.avium_104 LTLSVRPPVLTPAAPPARLCNESPV-------------------------
Mvan_5883|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3756|M.bovis_AF2122/97 DDTFDALVCECAFCTFPDKNAAAQQFARILRPGGLAGITDVTVGDGGLPA
Rv3729|M.tuberculosis_H37Rv DDTFDALVCECAFCTFPDKNAAAQQFARILRPGGLAGITDVTVGDGGLPA
MSMEG_5410|M.smegmatis_MC2_155 --------------------------------------------------
MAV_4478|M.avium_104 --------------------------------------------------
Mvan_5883|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3756|M.bovis_AF2122/97 ELTPLAAWVACIADARTVTDYTDILEGAGLRTRHIESHDESLLDMIDRID
Rv3729|M.tuberculosis_H37Rv ELTPLAAWVACIADARTVTDYTDILEGAGLRTRHIESHDESLLDMIDRID
MSMEG_5410|M.smegmatis_MC2_155 --------------------------------------------------
MAV_4478|M.avium_104 --------------------------------------------------
Mvan_5883|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3756|M.bovis_AF2122/97 ARITALHVAAPEILADNGIRHDSVRDFTALARAAVQTGRIGYTLMIAEKP
Rv3729|M.tuberculosis_H37Rv ARITALHVAAPEILADNGIRHDSVRDFTALARAAVQTGRIGYTLMIAEKP
MSMEG_5410|M.smegmatis_MC2_155 --------------------------------------------------
MAV_4478|M.avium_104 --------------------------------------------------
Mvan_5883|M.vanbaalenii_PYR-1 --------------------------------------------------