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M. smegmatis MC2 155 MSMEG_5392 (kdpA)

annotation: potassium-transporting ATPase subunit A
coordinates: 5468513 - 5470183
length: 556

VSPTTAGIAFLASLVAAVVLVHVPLGDYMYRVYTSEKDSRAERLIYRVIGADPRAEQSWGSYARSVLAFS
AVSIVFLFGLQLVQGRLPLHLHDPATPMTPALAWNTAVSFVTNTNWQAYAGESTQGHLVQMAGLAVQNFV
SAAVGMAVAIALVRGFARRHTGELGNFWVDLVRGNLRILLPLAIVGALLLVAGGAIQNFALHEQVVTTLS
GAAQTIPGGPVAGQEAIKELGTNGGGFFNVNSAHPFENPTPWTNWLENFLILLIPFSLPRTFGRMVGSAR
QGVAIAAIMGAIALASVSLTMLLQLQHHGTVPTAVGAAMEGVEQRFGVADSAVFAGSTTLTSTGAVNSFH
DSYTSLGGLMTMFNMQLGEIGPGGVGSGLYGMLILAIITVFVAGLMVGRTPEYLGKKITPREIKLAASYF
LATPLIVLTGSAIAMAMPGQRAGMLNTGPHGLSEVLYAFTSTANNNGSAFAGISVNTEWYNTALGLAMVF
GRLLPIILVLALAGSLASQGVTPSSVGTLPTHRPQFVGMTVGVTLILVALTFLPILALGPLAEGIH
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_5392kdpA-100% (556)potassium-transporting ATPase subunit A

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1058kdpA1e-15853.21% (560) potassium-transporting ATPase subunit A
M. gilvum PYR-GCK-----
M. tuberculosis H37RvRv1029kdpA1e-15853.21% (560) potassium-transporting ATPase subunit A
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_3254c-1e-16253.40% (573) potassium-transporting ATPase subunit A
M. marinum MMMAR_0631kdpA0.081.85% (551) potassium-transporting ATPase a subunit, KdpA
M. avium 104MAV_1173kdpA0.082.01% (556) potassium-transporting ATPase subunit A
M. thermoresistible (build 8)-----
M. ulcerans Agy99-----
M. vanbaalenii PYR-1Mvan_4759-0.081.83% (556) potassium-transporting ATPase subunit A

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_0631|M.marinum_M               ----MAGILFLASLMVALVAVHVPFGDYMYRVYT-----------SDKHS
Mvan_4759|M.vanbaalenii_PYR-1       MSTGLAGILFLASLVIALVAVHVPLGDYMYRVYN-----------TAKDS
MSMEG_5392|M.smegmatis_MC2_155      MSPTTAGIAFLASLVAAVVLVHVPLGDYMYRVYT-----------SEKDS
MAV_1173|M.avium_104                MSSTTAGLIFLAVLVAALVVVHVPLGDYMFRVYT-----------TDRDL
MAB_3254c|M.abscessus_ATCC_199      MNSALAAGLQIGFVILALAIAYVPLGDYMARVFTGPHSLRASGLSTIKHS
Mb1058|M.bovis_AF2122/97            MSG--TSWLQFAALIAVLLLTAPALGGYLAKIYG----DEAKKPGDRVFG
Rv1029|M.tuberculosis_H37Rv         MSG--TSWLQFAALIAVLLLTAPALGGYLAKIYG----DEAKKPGDRVFG
                                         :.   :. :: .:  .  .:*.*: :::                 

MMAR_0631|M.marinum_M               RVERWIYRAIGADPHAEQGWGAYARSVLAFSASGILVLFTFQLMQGKLPL
Mvan_4759|M.vanbaalenii_PYR-1       RAENVVYRLIGADPKAEQTWGAYARSVLAFSAVSLLFLFILQLVQGRLPS
MSMEG_5392|M.smegmatis_MC2_155      RAERLIYRVIGADPRAEQSWGSYARSVLAFSAVSIVFLFGLQLVQGRLPL
MAV_1173|M.avium_104                AAERTIYRLIGVDARSEQTWGAYARGVLAFSSVSIIFLFVLQLVQGKLPL
MAB_3254c|M.abscessus_ATCC_199      RVERLIYRVGRVDPETEQTWVGYTLSLLGFSFASVIFLYVLQRIQGVLP-
Mb1058|M.bovis_AF2122/97            PIERVIYQVCRVDPGSEQRWSTYALSVLAFSVMSFLLLYGIARFQGVLPF
Rv1029|M.tuberculosis_H37Rv         PIERVIYQVCRVDPGSEQRWSTYALSVLAFSVMSFLLLYGIARFQGVLPF
                                      *. :*:   .*. :** *  *: .:*.**  ..:.*: :  .** ** 

MMAR_0631|M.marinum_M               HLNDPATPMNPVLAWNTAVSFVTNTNWQAYSGESTQGHLVQMAGLAVQNF
Mvan_4759|M.vanbaalenii_PYR-1       ALTDPGTPMTPALAWNTAVSFVTNTNWQAYSGESTHGHLVQMAGLAVQNF
MSMEG_5392|M.smegmatis_MC2_155      HLHDPATPMTPALAWNTAVSFVTNTNWQAYAGESTQGHLVQMAGLAVQNF
MAV_1173|M.avium_104                HLHDPATKMTPSLAWNTAVSFVTNTNWQAYSGETTQGHLVQMAGLAVQNF
MAB_3254c|M.abscessus_ATCC_199      -LSGGLGAVSPAVAFNTAVSFVTNTNWQSYTPETTMSNLTQMVGLAVQNF
Mb1058|M.bovis_AF2122/97            NPTDKP-AVTDHVAFNAAVSFMTNTNWQSYSGEATMSHFTQMTGLAVQNF
Rv1029|M.tuberculosis_H37Rv         NPTDKP-AVTDHVAFNAAVSFMTNTNWQSYSGEATMSHFTQMTGLAVQNF
                                       .    :.  :*:*:****:******:*: *:* .::.**.*******

MMAR_0631|M.marinum_M               VSAAVGMAVAMAVVRGFARRHTG-DLGNFWVDLVRGTIRILLPVSVVAAI
Mvan_4759|M.vanbaalenii_PYR-1       VSAAVGMAVAIALVRGFARKRTG-ELGNFWVDLVRGTIRILLPISVIAAI
MSMEG_5392|M.smegmatis_MC2_155      VSAAVGMAVAIALVRGFARRHTG-ELGNFWVDLVRGNLRILLPLAIVGAL
MAV_1173|M.avium_104                VSAAVGMAVAVALVRGFARRRTG-ELGNFWVDLVRGTLRILLPISIVGAV
MAB_3254c|M.abscessus_ATCC_199      VSAAVGLTVAVALIRGVVRTTSGGELGNFWVDLVRGSLRILLPLSFAVAL
Mb1058|M.bovis_AF2122/97            VSASAGMCVLAALIRGLARKRAS-TLGNFWVDLARTVLRIMFPLSFVVAI
Rv1029|M.tuberculosis_H37Rv         VSASAGMCVLAALIRGLARKRAS-TLGNFWVDLARTVLRIMFPLSFVVAI
                                    ***:.*: *  *::**..*  :.  ********.*  :**::*::.  *:

MMAR_0631|M.marinum_M               VLVAGGAIQNFHLRDQIVSTLSGAEQTITGGPVASQETIKDLGTNGGGFF
Mvan_4759|M.vanbaalenii_PYR-1       LLITGGAIQNFHNYDQVVNTLAGAQQTIPGGPVASQEAIKDLGTNGGGFY
MSMEG_5392|M.smegmatis_MC2_155      LLVAGGAIQNFALHEQVVTTLSGAAQTIPGGPVAGQEAIKELGTNGGGFF
MAV_1173|M.avium_104                LLVAGGAIQNFHLHDQVVTTLGGTAQTIPGGPVASQEVIKELGTNGGGFY
MAB_3254c|M.abscessus_ATCC_199      ILLSQGTIQSVYTHFEAT-ALDGTAQHIALAPVASQEAIKEIGTNGGGIL
Mb1058|M.bovis_AF2122/97            LLVSQGVIQNLHG-FIVANTLEGAPQLIPGGPVASQVAIKQLGTNGGGFF
Rv1029|M.tuberculosis_H37Rv         LLVSQGVIQNLHG-FIVANTLEGAPQLIPGGPVASQVAIKQLGTNGGGFF
                                    :*:: *.**..      . :* *: * *. .***.* .**::******: 

MMAR_0631|M.marinum_M               NVNSAHPFENPTAWTNWVEIFLLLVISFSLPRTFGRMVGSPKQGIAIASV
Mvan_4759|M.vanbaalenii_PYR-1       NVNSAHPFENPTTWTNWIEIFLLLVIAFSLPRTFGRMVGNKKQGYAIVGV
MSMEG_5392|M.smegmatis_MC2_155      NVNSAHPFENPTPWTNWLENFLILLIPFSLPRTFGRMVGSARQGVAIAAI
MAV_1173|M.avium_104                NANSAHPFENPTAWTNWLEIFLILVIGFSLPRTFGRMVGNPKQGYAIASV
MAB_3254c|M.abscessus_ATCC_199      GANSAHPFENPTPLSNVIEILAILIIPVCLTRTYSTMVGDKRQGLTVLSV
Mb1058|M.bovis_AF2122/97            NVNSAHPFENYTPIGNFVENWAILIIPFALCFAFGKMVHDRRQGWAVLAI
Rv1029|M.tuberculosis_H37Rv         NVNSAHPFENYTPIGNFVENWAILIIPFALCFAFGKMVHDRRQGWAVLAI
                                    ..******** *.  * :*   :*:* ..*  ::. ** . :** :: .:

MMAR_0631|M.marinum_M               MAVLALISWSTTMSMQLQ----------RHGTVPTAVGAAMEGVEQRFGV
Mvan_4759|M.vanbaalenii_PYR-1       QAVLAVISWSATLFFQLQ----------AHGTVPTAVGAAMEGVEQRFGV
MSMEG_5392|M.smegmatis_MC2_155      MGAIALASVSLTMLLQLQ----------HHGTVPTAVGAAMEGVEQRFGV
MAV_1173|M.avium_104                MASLYLLSTGFMLWFQLQ----------HHGTVPSAVGAAMEGVEQRFGV
MAB_3254c|M.abscessus_ATCC_199      MGTLFGGMLALVTWAESS----------PRGIAAQAAGAMMEGKEVRFGI
Mb1058|M.bovis_AF2122/97            MGIIWIGMSVAAMSFEAKGNPRLDALGVTQQTTVDQSGGNLEGKEVRFGV
Rv1029|M.tuberculosis_H37Rv         MGIIWIGMSVAAMSFEAKGNPRLDALGVTQQTTVDQSGGNLEGKEVRFGV
                                     . :           : .           :  .    *. :** * ***:

MMAR_0631|M.marinum_M               ANSAVFAASTTLTSTGSVDSFHDSYTSLGGLVLLLNMQLGEVAPGGVGSG
Mvan_4759|M.vanbaalenii_PYR-1       ANSAVFAASTTLTSTGSVDSFHDSYTSLGGLVLLFNMQLGEVAPGGVGAG
MSMEG_5392|M.smegmatis_MC2_155      ADSAVFAGSTTLTSTGAVNSFHDSYTSLGGLMTMFNMQLGEIGPGGVGSG
MAV_1173|M.avium_104                PDSGVFAAATTLTSTGAVDSAHDSLTSLGGMITMFNMQLGEVAPGGTGSG
MAB_3254c|M.abscessus_ATCC_199      PGSALFAVSTTGTSTGAVDAAHDSFTAAGGGALILNMLLGEIAPGGVGTG
Mb1058|M.bovis_AF2122/97            GASGLWAASTTGTSNGSVNSMHDSYTPLGGMVPLAHMMLGEVSPGGTGVG
Rv1029|M.tuberculosis_H37Rv         GASGLWAASTTGTSNGSVNSMHDSYTPLGGMVPLAHMMLGEVSPGGTGVG
                                      *.::* :** **.*:*:: *** *. **   : :* ***:.***.* *

MMAR_0631|M.marinum_M               LFGMLILAVITVFIAGLMVGRTPEYLGKKITPREIKLAATYLLISPLIAL
Mvan_4759|M.vanbaalenii_PYR-1       LYGILILAVITVFVAGLMVGRTPEYLGKKITPREIKLAATYFLVTPLIVL
MSMEG_5392|M.smegmatis_MC2_155      LYGMLILAIITVFVAGLMVGRTPEYLGKKITPREIKLAASYFLATPLIVL
MAV_1173|M.avium_104                LYGMLVLAVITVFVAGLMVGRTPEYLGKKINPREIKLAASYFLVTPLIVL
MAB_3254c|M.abscessus_ATCC_199      LYGILVLAIIAVFVGGLLVGRTPEFLGKKIGRRQITMAALSVLVMPALVL
Mb1058|M.bovis_AF2122/97            LNGLLVMAILAVFIAGLMVGRTPEYLGKKIQATEMKLVTLYILAMPIALL
Rv1029|M.tuberculosis_H37Rv         LNGLLVMAILAVFIAGLMVGRTPEYLGKKIQATEMKLVTLYILAMPIALL
                                    * *:*::*:::**:.**:******:*****   ::.:.:  .*  *   *

MMAR_0631|M.marinum_M               TGSAVAMAMPGQRAAMLNTGP-------HGLSEVLYAFTSAANNNGSAFA
Mvan_4759|M.vanbaalenii_PYR-1       TGTAVAMAMPGQRAGMLNTGP-------HGLSEVLYAFTSAANNNGSAFA
MSMEG_5392|M.smegmatis_MC2_155      TGSAIAMAMPGQRAGMLNTGP-------HGLSEVLYAFTSTANNNGSAFA
MAV_1173|M.avium_104                TGTAIAMALPGERAGMANSGP-------HGLSEVLYAFTSAANNNGSAFA
MAB_3254c|M.abscessus_ATCC_199      VGTGISVALSTTTGYQGNSGDPGTPSSIHGFSEVLYAYASAANNNGSAFG
Mb1058|M.bovis_AF2122/97            SFAAASVLISSALASRNNPGP-------HGLSEILYAYTSGANNNGSAFA
Rv1029|M.tuberculosis_H37Rv         SFAAASVLISSALASRNNPGP-------HGLSEILYAYTSGANNNGSAFA
                                      :. :: :.   .   *.*        **:**:***::* ********.

MMAR_0631|M.marinum_M               GISVNTDWYNTALGLAMVFGRFLPIVLVLALAGSLVRQGTTPESIGTLPT
Mvan_4759|M.vanbaalenii_PYR-1       GITVNTEWYNTALGLAMVFGRFLPIILALALAGSLAQQGKTPPSIGTLPT
MSMEG_5392|M.smegmatis_MC2_155      GISVNTEWYNTALGLAMVFGRLLPIILVLALAGSLASQGVTPSSVGTLPT
MAV_1173|M.avium_104                GLSANTEWYNTALGLAMAFGRFLPIVLVLALAGSLARQGSTPDSAGTLPT
MAB_3254c|M.abscessus_ATCC_199      GLTVTSHWFQASLGMAMLLGRFLPIIFTLALAGSLATQRKTPASAGTLHT
Mb1058|M.bovis_AF2122/97            GLTASTWSYDTTIGVAMLIGRFFLIIPVLAIAGSLARKGTTPVTAATFPT
Rv1029|M.tuberculosis_H37Rv         GLTASTWSYDTTIGVAMLIGRFFLIIPVLAIAGSLARKGTTPVTAATFPT
                                    *::..:  :::::*:** :**:: *: .**:****. :  ** : .*: *

MMAR_0631|M.marinum_M               HRPQFVGLVAGVTLILVALTFLPMLALGPLAEGIH--
Mvan_4759|M.vanbaalenii_PYR-1       HRPQFVGMVAGVTLILVALTFLPMLALGPLAEGIH--
MSMEG_5392|M.smegmatis_MC2_155      HRPQFVGMTVGVTLILVALTFLPILALGPLAEGIH--
MAV_1173|M.avium_104                HRPQFVGMVAGVTLIVVALTFLPMLALGPLAEGIH--
MAB_3254c|M.abscessus_ATCC_199      HGPMFAGLHTGTVLLVAALTFFPALALGPIAEAVL--
Mb1058|M.bovis_AF2122/97            HKPLFVGLVIGVVLIVGGLTFFPALALGPIVEQLSTQ
Rv1029|M.tuberculosis_H37Rv         HKPLFVGLVIGVVLIVGGLTFFPALALGPIVEQLSTQ
                                    * * *.*:  *..*:: .***:* *****:.* :