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M. smegmatis MC2 155 MSMEG_5338 (-)

annotation: regulatory protein, MarR
coordinates: 5423695 - 5424123
length: 142

AAGQQRRPNLLLPLVRLTHLAESAIERVLADSSLKIEDWRVLDELAGRRTVPMSDLAQATLITGPTLTRT
VDRLVSQGIIYRTADLHDRRRVLVALTPRGRTLRNRLVDAVAEAECAAFESCGLDVDQLRELVDTTSNLT
S*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_5338--100% (142)regulatory protein, MarR
M. smegmatis MC2 155MSMEG_6814-3e-0834.62% (78) helix-turn-helix, Fis-type
M. smegmatis MC2 155MSMEG_2476-3e-0626.67% (120) MarR family protein transcriptional regulatory protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2354-5e-0733.33% (108) hypothetical protein Mb2354
M. gilvum PYR-GCKMflv_2729-1e-0730.30% (132) MarR family transcriptional regulator
M. tuberculosis H37RvRv2327-5e-0733.33% (108) hypothetical protein Rv2327
M. leprae Br4923MLBr_02696-8e-0838.57% (70) putative MarR-family regulatory protein
M. abscessus ATCC 19977MAB_0208-5e-0836.71% (79) MarR family transcriptional regulator
M. marinum MMMAR_3627-1e-0630.66% (137) hypothetical protein MMAR_3627
M. avium 104MAV_2081-6e-0729.87% (154) transcriptional regulator, MarR family protein
M. thermoresistible (build 8)TH_0729-5e-0733.33% (105) CONSERVED HYPOTHETICAL PROTEIN
M. ulcerans Agy99MUL_1238-9e-0730.66% (137) hypothetical protein MUL_1238
M. vanbaalenii PYR-1Mvan_0651-9e-1542.72% (103) MarR family transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


Mb2354|M.bovis_AF2122/97            ---------------------------------------------MSPSP
Rv2327|M.tuberculosis_H37Rv         ---------------------------------------------MSPSP
MMAR_3627|M.marinum_M               ---------------------------------------------MTSS-
MUL_1238|M.ulcerans_Agy99           ---------------------------------------------MTSS-
MAV_2081|M.avium_104                ---------------------------------------------MDNVV
Mflv_2729|M.gilvum_PYR-GCK          -----------------------------------------------MS-
TH_0729|M.thermoresistible__bu      ----------------------------------------MKPPAVDPS-
MLBr_02696|M.leprae_Br4923          MFSYITTKSWNPGNQSRYSRPRRLSAYNGLYPKYFDVLDFTNDDPLHPAP
MSMEG_5338|M.smegmatis_MC2_155      ---------------------------------------------MAAG-
Mvan_0651|M.vanbaalenii_PYR-1       ---------------------------------------------MVSAR
MAB_0208|M.abscessus_ATCC_1997      ---------------------------------------------MSTRS
                                                                                      

Mb2354|M.bovis_AF2122/97            AAANRSEVGGPLPGLGADLLAVVARLN-----------------------
Rv2327|M.tuberculosis_H37Rv         AAANRSEVGGPLPGLGADLLAVVARLN-----------------------
MMAR_3627|M.marinum_M               ATANQAQVA---HGLGADLLAVVARLN-----------------------
MUL_1238|M.ulcerans_Agy99           ATANQAQVA---HGLGADLLAVVARLN-----------------------
MAV_2081|M.avium_104                DTAK-LEGG---QGLGADLLAVVARLN-----------------------
Mflv_2729|M.gilvum_PYR-GCK          ------------STLGSDLLSVVARIN-----------------------
TH_0729|M.thermoresistible__bu      ------------TSLGADLLWVVSRIN-----------------------
MLBr_02696|M.leprae_Br4923          PHLRPPLQLAHTRSLNARHIALNCRLMADSEFTAHEVTELADGLHRALSK
MSMEG_5338|M.smegmatis_MC2_155      ------------QQRRPNLLLPLVRLTHLAES------------------
Mvan_0651|M.vanbaalenii_PYR-1       SMVTVATGS---DSVSEVFFRAERRWT-----------------------
MAB_0208|M.abscessus_ATCC_1997      ESEVPGLDLAEFRSWQN-FWVATNRLN-----------------------
                                                            *                         

Mb2354|M.bovis_AF2122/97            -------RLATQRIQMPLPAAQ-ARLLATIE--AQGEARIGDLAAVDHCS
Rv2327|M.tuberculosis_H37Rv         -------RLATQRIQMPLPAAQ-ARLLATIE--AQGEARIGDLAAVDHCS
MMAR_3627|M.marinum_M               -------RLATQRIQMPLPSAQ-ARLLATIE--AQGEARIGDLAAVDHCS
MUL_1238|M.ulcerans_Agy99           -------RLATQRIQMPLPSAQ-ARLLATIE--AQGEARIGDLAAVDHCS
MAV_2081|M.avium_104                -------RLATQRIQMPLPAAQ-ARLLATIE--AHGEARIGDLAAVDHCS
Mflv_2729|M.gilvum_PYR-GCK          -------RLANQRVRMPVPFAQ-ARLLSTIE--DRGEARISDLAALDHCS
TH_0729|M.thermoresistible__bu      -------RLATQRIRLPLPVAQ-ARLLSTIQ--DRGSARISDLAVLDHCS
MLBr_02696|M.leprae_Br4923          LFSILRRRTPNGAVSGELTLAQ-LSILVTLL--DQGPIRMTDLAAHERVR
MSMEG_5338|M.smegmatis_MC2_155      -------AIERVLADSSLKIED-WRVLDELA--GRRTVPMSDLAQATLIT
Mvan_0651|M.vanbaalenii_PYR-1       ------EALCRGLLDGDIAAIEGWRILGMLR--GGDGLTMSDISSAMSIP
MAB_0208|M.abscessus_ATCC_1997      ------FLLNRKMVASHSISLTDFHVLQQLLRSANGSCRMGDIANSLLAS
                                                             :*  :         : *::      

Mb2354|M.bovis_AF2122/97            QPTMTTQVRRLEDAGLVTRTADPGDARAVRIRITPEGIRTLTAVRADR-A
Rv2327|M.tuberculosis_H37Rv         QPTMTTQVRRLEDAGLVTRTADPGDARAVRIRITPEGIRTLTAVRADR-A
MMAR_3627|M.marinum_M               QPTMTTQVRRLEDAGMVTRTVDPGDARAVRIRITPEGMRTLSAVRTDR-A
MUL_1238|M.ulcerans_Agy99           QPTMTTQVRRLEDAGMVTRTVDPGDARAVRIRITPEGMRTLSAVRTDR-A
MAV_2081|M.avium_104                QPTMTTQVRRLEEAGLVTRTVDPGDARAVRIRITAEGRRTLNAVRADR-A
Mflv_2729|M.gilvum_PYR-GCK          QPTMTTQVRRLEDAGLVARTADPNDARAVLIRITPAGVSALRQARADR-G
TH_0729|M.thermoresistible__bu      QPTMTTQVRRLEEAGLVSRTVDPDDGRAVRISITPEGVRTLAQVRADR-A
MLBr_02696|M.leprae_Br4923          TPTTTVAIRRLEKIGLVKRSRDLSDLRAVLVDITPRGRTVHGESLANR-R
MSMEG_5338|M.smegmatis_MC2_155      GPTLTRTVDRLVSQGIIYRTADLHDRRRVLVALTPRG-RTLRNRLVDA-V
Mvan_0651|M.vanbaalenii_PYR-1       PPTLTRIVDKLVEGGFVIRRVDAADRRRVLIYLSARGKTKVRKLVKQE-S
MAB_0208|M.abscessus_ATCC_1997      RSRITHQVRRLEEQGLVKRGSMPQDRRAVLAALTEQGRTLGEAAMRTYSE
                                     .  *  : :* . *:: *     * * *   ::  *             

Mb2354|M.bovis_AF2122/97            AAIEPQLALLPPADRRVLADAVDVLRRLLDHAATTP---GRATRQ-----
Rv2327|M.tuberculosis_H37Rv         AAIEPQLALLPPADRRVLADAVDVLRRLLDHAATTP---GRATRQ-----
MMAR_3627|M.marinum_M               AAIEPQLARLEPSDRQVLADAVEVLRRLLDNAAATP---GRNTL------
MUL_1238|M.ulcerans_Agy99           AAIEPQLARLEPSDRQVLAGAVEVLRRLLDNAAATP---GRNTL------
MAV_2081|M.avium_104                AAIQPQLALLDAEDRQVLRQAVDVLRRLLDNASLASSLAGRRQTSLRLVA
Mflv_2729|M.gilvum_PYR-GCK          AAVDPYLERLDDTDRATLTQAVDIMRRLVEDATSPSAVPR----------
TH_0729|M.thermoresistible__bu      AAIDPYIDRLSDTDRAVLADAVRVMRQLLADAADPAVLPADPPSRPHEST
MLBr_02696|M.leprae_Br4923          AALTTMLSQLPTSDLNILKNALAPLQRLASGEPVSSPAGDSPACKQA---
MSMEG_5338|M.smegmatis_MC2_155      AEAECAAFESCGLDVDQLRELVDTTSNLTS--------------------
Mvan_0651|M.vanbaalenii_PYR-1       LVKAALVEELGEDAAVGFIRALARVGDLPL--------------------
MAB_0208|M.abscessus_ATCC_1997      CVREHYLMRLTRPQQAAIAESFRRVGEGAEEALHDGDGRGGE--------
                                                     :   .                            

Mb2354|M.bovis_AF2122/97            --------
Rv2327|M.tuberculosis_H37Rv         --------
MMAR_3627|M.marinum_M               --------
MUL_1238|M.ulcerans_Agy99           --------
MAV_2081|M.avium_104                GPGARVDT
Mflv_2729|M.gilvum_PYR-GCK          --------
TH_0729|M.thermoresistible__bu      ELR-----
MLBr_02696|M.leprae_Br4923          --------
MSMEG_5338|M.smegmatis_MC2_155      --------
Mvan_0651|M.vanbaalenii_PYR-1       --------
MAB_0208|M.abscessus_ATCC_1997      --------