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TRFIQQAREPEVCHEAPEQIRRRRIVVSVFLLIGAGLLGYSLTRSPGDGSFLWLTLVLAAVWAVGAFVSG PLHLGYLHVRGRDRRPALAGAVVGITLAGVFVVGALIAREIPGIREFITRVLEFSNTGPLALIVFITVIN GVAEELFFRGALYSALGKFYPVVVSTLIYIVTTMASGNPMLGFAAIILGAVCAMERRVTGGVLAPMLTHF FWGLAMVLALPPIFGV*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_5188 | - | - | 100% (227) | caax amino protease family protein |
| M. smegmatis MC2 155 | MSMEG_3474 | - | 2e-05 | 33.72% (86) | integral membrane protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1172 | - | 8e-76 | 62.91% (213) | integral membrane protein |
| M. gilvum PYR-GCK | Mflv_2123 | - | 4e-83 | 66.36% (214) | abortive infection protein |
| M. tuberculosis H37Rv | Rv1140 | - | 8e-76 | 62.91% (213) | integral membrane protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_4311 | - | 6e-78 | 63.85% (213) | integral membrane protein |
| M. avium 104 | MAV_1282 | - | 1e-78 | 64.79% (213) | caax amino protease family protein |
| M. thermoresistible (build 8) | TH_1985 | - | 1e-92 | 75.57% (221) | PROBABLE INTEGRAL MEMBRANE PROTEIN |
| M. ulcerans Agy99 | MUL_0983 | - | 9e-78 | 63.38% (213) | integral membrane protein |
| M. vanbaalenii PYR-1 | Mvan_4582 | - | 1e-85 | 68.22% (214) | abortive infection protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1172|M.bovis_AF2122/97 MPRDYTAPRWAHAWAGEPRPARWHPANQPAHPDHSNRESPACMSQSTTPY
Rv1140|M.tuberculosis_H37Rv MPRDYTAPRWAHAWAGEPRPARWHPANQPAHPDHSNRESPACMSQSTTPY
MAV_1282|M.avium_104 ------------------------------------------MSQSTSPY
MMAR_4311|M.marinum_M ------------------------------------------MSQSTAP-
MUL_0983|M.ulcerans_Agy99 ------------MGEHRPGSTGRCVTKQPRHPDRPDSESSVRMSQSTAP-
MSMEG_5188|M.smegmatis_MC2_155 ------------------------------------------MTR-----
TH_1985|M.thermoresistible__bu ------------------------------------------MTDRGVL-
Mflv_2123|M.gilvum_PYR-GCK ------------------------------------------MTAPTSW-
Mvan_4582|M.vanbaalenii_PYR-1 ------------------------------------------MSAPTSW-
*:
Mb1172|M.bovis_AF2122/97 RSSVLAEFRRAITNVAVPHHEPPGIVRRRRVVVGVTLVIGAVMLGFSLRR
Rv1140|M.tuberculosis_H37Rv RSSVLAEFRRAITNVAVPHHEPPGIVRRRRVVVGVTLVIGAVMLGFSLRR
MAV_1282|M.avium_104 HTSVFAELRRAITNVAVPHNEPPAIVRRRRVVVAITLVLGAAVLGYSLRR
MMAR_4311|M.marinum_M QFSAIDDIRRAITNVAVPHHEAPSVVLRRRIVVGVVLVIGAVVMGLSMRR
MUL_0983|M.ulcerans_Agy99 QFSAIDDIRRAITNVAVPHHEAPSVVLRRRIVVGVVLVIGAVVMGLSMRR
MSMEG_5188|M.smegmatis_MC2_155 -------FIQQAREPEVCH-EAPEQIRRRRIVVSVFLLIGAGLLGYSLTR
TH_1985|M.thermoresistible__bu ----R-EFGDIARTVAVPHQETPAVVRRRRVIVIVVLLIGSGLLAYSLTR
Mflv_2123|M.gilvum_PYR-GCK ----AGELRKIAATKAPPYNEPPSVVGRRKVIVAVVLLIGAALLGYSLSR
Mvan_4582|M.vanbaalenii_PYR-1 ----AGELRRIARGKARPYNEPPSVVNRRKLIVGVVLLVGAALLGYSLSR
: : *.* : **:::* : *::*: ::. *: *
Mb1172|M.bovis_AF2122/97 TPGESSFYWLTLALAAVWIAGALMSGPLHLGGICWRGRNQRPVITGTTVG
Rv1140|M.tuberculosis_H37Rv TPGESSFYWLTLALAAVWIAGALMSGPLHLGGICWRGRNQRPVITGTTVG
MAV_1282|M.avium_104 HPGESSFYWLTLGLAAVWTVGALSSGPLHLGGICWRGRNQRPVITGTTVG
MMAR_4311|M.marinum_M QPGESTFYWLTLTLAAVWALGALASGPLHLGGIRWRGRNQRPVITGTTIG
MUL_0983|M.ulcerans_Agy99 QPGEATFYWLTLTLAAVWALGSLASGPLHLGGIRWRGRNQRPVITGTTIG
MSMEG_5188|M.smegmatis_MC2_155 SPGDGSFLWLTLVLAAVWAVGAFVSGPLHLGYLHVRGRDRRPALAGAVVG
TH_1985|M.thermoresistible__bu PPGDQSFYWLTLVLAAVWAVGALVSGPLHLGCVRFRGRNQRPVITGTVVG
Mflv_2123|M.gilvum_PYR-GCK PPGDETFIWLTLALAGVWAAGAFASGPLHMGYVCFRGRNQRPVITGTAIG
Mvan_4582|M.vanbaalenii_PYR-1 PAGDETFIWLTLALAGVWAAGAFASGPLHMGHVCFRGRNQRPVITGTAIG
.*: :* **** **.** *:: *****:* : ***::**.::*:.:*
Mb1172|M.bovis_AF2122/97 LLLAGIFGVGAMIVRAIPGAAEPIARVLQFAHQGTLLPILLITLINGIAE
Rv1140|M.tuberculosis_H37Rv LLLAGIFGVGAMIVRAIPGAAEPIARVLQFAHQGTLLPILLITLINGIAE
MAV_1282|M.avium_104 LLLGGAFVVGGLIAREIPAVSALITRVLLYAHHGWLPLVVAITVINGIAE
MMAR_4311|M.marinum_M LLLGGIFVLGALVVRKIPAAAELIVRVLQFASQGSLFLVVVITLINGIAE
MUL_0983|M.ulcerans_Agy99 LLLGGIFVLGALVVRKIPAATELIVRVLQFASQGSLFLVVVITLINGIAE
MSMEG_5188|M.smegmatis_MC2_155 ITLAGVFVVGALIAREIPGIREFITRVLEFSNTGPLALIVFITVINGVAE
TH_1985|M.thermoresistible__bu LLLGGLFVVGGLIAREIPGVRDYITRVLEFSNHGPLLLVVFITVINGLAE
Mflv_2123|M.gilvum_PYR-GCK LGLGAVFVLGALVVREIPGVNDYIRAVLQYSNAGPLYVIVFITVINGVAE
Mvan_4582|M.vanbaalenii_PYR-1 LALGAIFVVGALIVREVPGLNDYITRVLEYSNTGPLWLIVFITVINGVAE
: *.. * :*.::.* :*. * ** :: * * :: **:***:**
Mb1172|M.bovis_AF2122/97 EMFFRGALYTALGRRYPVTISTVLYVGATMAS-ANLMLGFAAIFVGTVCA
Rv1140|M.tuberculosis_H37Rv EMFFRGALYTALGRRYPVTISTVLYVGATMAS-ANLMLGFAAIFVGTVCA
MAV_1282|M.avium_104 ELFFRGALYTALGRYHPVLISTLLYTAATMAA-GNPMLGFAAVILGTVCA
MMAR_4311|M.marinum_M EMFFRGALYTALGRFYPVAVSTVVYIGAIMAS-ANLMLGFAAVILGGVCA
MUL_0983|M.ulcerans_Agy99 EMFFRGALYTALGRFYPVAVSTVVYIGAIMAS-ANLMLGFAAVILGGVCA
MSMEG_5188|M.smegmatis_MC2_155 ELFFRGALYSALGKFYPVVVSTLIYIVTTMAS-GNPMLGFAAIILGAVCA
TH_1985|M.thermoresistible__bu ELFFRGALYTALGTAYPAVISTIIYIGVTSAT-GNPMLGFAAIILGAVCA
Mflv_2123|M.gilvum_PYR-GCK EMFFRGAVYTSLLKFHPVIVSTALYVIATAATTGNPMLGFAAIILGTVCA
Mvan_4582|M.vanbaalenii_PYR-1 EMFFRGAVYTALLKFHPVIFSTVLYVIATAATTGNPMLGFAAIILGTVCA
*:*****:*::* :*. .** :* . *: .* ******:::* ***
Mb1172|M.bovis_AF2122/97 LERRASGGVLAPILTHFVWGLIMVFALPPLFAV
Rv1140|M.tuberculosis_H37Rv LERRASGGVLAPILTHFVWGLIMVFALPPLFAV
MAV_1282|M.avium_104 LERRASGGVLAPVLTHCGWGLIMVLALPPVFGL
MMAR_4311|M.marinum_M WERRSTGGVLAPILTHLVWGLIMVLALPPLFGV
MUL_0983|M.ulcerans_Agy99 WERRSTGGVLAPILTHLVWGLIMVLALPPLFGV
MSMEG_5188|M.smegmatis_MC2_155 MERRVTGGVLAPMLTHFFWGLAMVLALPPIFGV
TH_1985|M.thermoresistible__bu FERRMTGGVLAPMLTHFFWGLIMVLALPPIFGV
Mflv_2123|M.gilvum_PYR-GCK FLRRATGGVLAPMLTHFFWGLVMVLALPPMFGV
Mvan_4582|M.vanbaalenii_PYR-1 FERRATGGVLAPMLTHFFWGLVMVLALPPIFGV
** :******:*** *** **:****:*.: