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VRQRRSATLPEFPWDTLADVTALARSHPDGIVDLSVGTPVDPVAPVIRDALAAGSSSPGYPTTAGTPELR EAMVRALDRRYGITGLTPQTVLPVIGTKELIAWLPTLLGLGSDDVVVVPELAYPTYEVGARLAGAQVLRA DSLTQIGPQVPALIYLNSPSNPTGRVLGRDHLRKVVTWARERGVLVASDECYLGLSWDADPVSVLHPSVC DGDHTGLLAIHSLSKTSSLAGYRAGFVAGDPAVVAELLAVRKHAGMMVPGPIQVAMVAALDDDEHEALQR DRYAQRRNLLLPAFREAGFTVDHSEAGLYLWATRGEACRDTLRWLAERGILVAPGEFYGPAGDRYVRVAL TATDERIQQAAERLAG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_5121 | - | - | 100% (367) | N-succinyldiaminopimelate aminotransferase |
| M. smegmatis MC2 155 | MSMEG_5725 | - | 8e-23 | 29.49% (390) | aminotransferase |
| M. smegmatis MC2 155 | MSMEG_6017 | - | 3e-22 | 25.52% (384) | aspartate aminotransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1211 | - | 1e-166 | 79.11% (359) | N-succinyldiaminopimelate aminotransferase |
| M. gilvum PYR-GCK | Mflv_2171 | - | 1e-170 | 83.01% (359) | N-succinyldiaminopimelate aminotransferase |
| M. tuberculosis H37Rv | Rv1178 | - | 1e-166 | 79.11% (359) | N-succinyldiaminopimelate aminotransferase |
| M. leprae Br4923 | MLBr_01488 | - | 1e-163 | 78.45% (362) | N-succinyldiaminopimelate aminotransferase |
| M. abscessus ATCC 19977 | MAB_1328 | - | 1e-153 | 73.82% (359) | N-succinyldiaminopimelate aminotransferase |
| M. marinum M | MMAR_4273 | - | 1e-166 | 78.67% (361) | aminotransferase |
| M. avium 104 | MAV_1317 | - | 1e-163 | 76.90% (368) | N-succinyldiaminopimelate aminotransferase |
| M. thermoresistible (build 8) | TH_1831 | - | 1e-151 | 81.11% (323) | PROBABLE AMINOTRANSFERASE |
| M. ulcerans Agy99 | MUL_1026 | - | 1e-164 | 78.12% (361) | N-succinyldiaminopimelate aminotransferase |
| M. vanbaalenii PYR-1 | Mvan_4528 | - | 1e-170 | 83.33% (354) | N-succinyldiaminopimelate aminotransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2171|M.gilvum_PYR-GCK MRTEPTAELARRRLRAPVSASLPVFPWDTLADVTAAARAHESGIVDLSVG
Mvan_4528|M.vanbaalenii_PYR-1 -----------------------MFPWDTLADATAAARAHPDGIVDLSVG
TH_1831|M.thermoresistible__bu --------------------------------------------------
MSMEG_5121|M.smegmatis_MC2_155 ------------MVRQRRSATLPEFPWDTLADVTALARSHPDGIVDLSVG
Mb1211|M.bovis_AF2122/97 -----------------MSASLPVFPWDTLADAKALAGAHPDGIVDLSVG
Rv1178|M.tuberculosis_H37Rv -----------------MSASLPVFPWDTLADAKALAGAHPDGIVDLSVG
MMAR_4273|M.marinum_M ----------MR-----VSASLPEFPWDTLAEAKARAGAHPDGIVDLSVG
MUL_1026|M.ulcerans_Agy99 ----------MR-----VSASLPEFPWDTLAEAKARAGAHPDGIVDLSVG
MAV_1317|M.avium_104 ------MPHQLRKRRPAVSAALPEFPWDTLAEAKALAGSHPDGIVDLSVG
MLBr_01488|M.leprae_Br4923 ------MSPFGR-----VSATLPVFPWDTLADAKAVAESHPDGIVDLSVG
MAB_1328|M.abscessus_ATCC_1997 -----------------MSASLPEFPWDTIADAKAAAAAHPDGIVDLSVG
Mflv_2171|M.gilvum_PYR-GCK TPVDEVAPVIRDALAAAGSAPGYPTTHGTTALRDAAVAALHRRYGITGLD
Mvan_4528|M.vanbaalenii_PYR-1 TPVDDVAPVIRDALAAASSAPGYPTTHGTPALREAAVSALRRRYGITHLA
TH_1831|M.thermoresistible__bu -----VAPVIRAALAEASAAPGYPTTAGTPALRASAAAALERRYGITGLT
MSMEG_5121|M.smegmatis_MC2_155 TPVDPVAPVIRDALAAGSSSPGYPTTAGTPELREAMVRALDRRYGITGLT
Mb1211|M.bovis_AF2122/97 TPVDPVAPLIQEALAAASAAPGYPATAGTARLRESVVAALARRYGITRLT
Rv1178|M.tuberculosis_H37Rv TPVDPVAPLIQEALAAASAAPGYPATAGTARLRESVVAALARRYGITRLT
MMAR_4273|M.marinum_M TPVDPVAPLVQEALTAAAFSPGYPATAGTAGLRESAVAALARRYGITELA
MUL_1026|M.ulcerans_Agy99 TPVDPVAPLVQEALTAAAFSPGYPATAGTAGLRESAGAALARRYGITELA
MAV_1317|M.avium_104 TPVDPVAPVIQQALAAAGSASGYPATAGTARLRDSAVAALARRFGVVGLT
MLBr_01488|M.leprae_Br4923 TPVDPVAPLIQEALAAASSVAGYPTTAGTARLREAAVAALDRRYGITGLT
MAB_1328|M.abscessus_ATCC_1997 TPVDSVAPVIRDALAAASDLPGYPATAGTPALRQAIRDAVTRRYGVVPLA
***::: **: .. .***:* **. ** : *: **:*:. *
Mflv_2171|M.gilvum_PYR-GCK PAAVLPVIGTKELIAWLPTLLGLGAADTVVVPELAYPTYEVGALLAGAAV
Mvan_4528|M.vanbaalenii_PYR-1 PGSVLPAIGTKELIAWLPTVLGLGAGDTVVVPELAYPTYEVGALLAGAAV
TH_1831|M.thermoresistible__bu PDAVLPAIGTKELIAWLPTLLGLGGDDTVVVPELAYPTYDVGARLAGARV
MSMEG_5121|M.smegmatis_MC2_155 PQTVLPVIGTKELIAWLPTLLGLGSDDVVVVPELAYPTYEVGARLAGAQV
Mb1211|M.bovis_AF2122/97 EAAVLPVIGTKELIAWLPTLLGLGGADLVVVPELAYPTYDVGARLAGTRV
Rv1178|M.tuberculosis_H37Rv EAAVLPVIGTKELIAWLPTLLGLGGADLVVVPELAYPTYDVGARLAGTRV
MMAR_4273|M.marinum_M ESAVLPVIGTKEFIAWLPTLLGLGSADAVVVPELAYPTYEVGARLAGARV
MUL_1026|M.ulcerans_Agy99 ESAVLPVIGTKEFIAWLPTLLGLGSADAVVVPELAYPTYEVGARLAGARV
MAV_1317|M.avium_104 EASVLPVIGSKELIAWLPTLLGLGPADLIVVPELAYPTYDVGARLAGARV
MLBr_01488|M.leprae_Br4923 EAAVLPVIGTKELIAWLPTLLGLRAGDVVVVPELAYPTYNVGARLAGARV
MAB_1328|M.abscessus_ATCC_1997 DNAVLPVIGTKELIAWLPTLLGLGADDLIVIPELAYPTYEVGARLAQVPT
:***.**:**:******:*** * :*:********:*** ** . .
Mflv_2171|M.gilvum_PYR-GCK VRADSLTQLGPAAPPLVYLNSPSNPTGKVLGVDHLRKVVGWARDRGVLVA
Mvan_4528|M.vanbaalenii_PYR-1 ARADSLTQLGPSVPALVYVNSPSNPTGRVLGVDHLRKVVGWARDRGVLVA
TH_1831|M.thermoresistible__bu FRADSLTQLGPQTPALIYLNSPSNPTGRVLGVDHLRKVVGWARDRGVIVA
MSMEG_5121|M.smegmatis_MC2_155 LRADSLTQIGPQVPALIYLNSPSNPTGRVLGRDHLRKVVTWARERGVLVA
Mb1211|M.bovis_AF2122/97 LRADALTQLGPQSPALLYLNSPSNPTGRVLGVDHLRKVVEWARGRGVLVV
Rv1178|M.tuberculosis_H37Rv LRADALTQLGPQSPALLYLNSPSNPTGRVLGVDHLRKVVEWARGRGVLVV
MMAR_4273|M.marinum_M QRADSLTQLGPQSPALLYLNSPSNPTGRVLGMEHLQKVVEWARGRGVIVA
MUL_1026|M.ulcerans_Agy99 QWADSLTQLGPQSPALLYLNSPSNPTGRVLGMEHLQKVVEWARGRGVIVA
MAV_1317|M.avium_104 LRADSLTQVGPQSPALYYLNSPSNPTGRVLGVDHLRKVAAWARDRGCLVA
MLBr_01488|M.leprae_Br4923 LRADSLTQLGLQSPALFYLNSPSNPTGQVLAVNHLRKMVGWARNRGVVVV
MAB_1328|M.abscessus_ATCC_1997 VRADSLTQLGPQRPTLIYLNSPSNPTGAVLPVEHLRKVVEWARERGALVV
**:***:* *.* *:******** ** :**:*:. *** ** :*.
Mflv_2171|M.gilvum_PYR-GCK SDECYLGLGWDATPVSVLHPDVCDGDHTGLLAIHSLSKTSSLAGYRAGFV
Mvan_4528|M.vanbaalenii_PYR-1 SDECYLGLGWDVAPVSVLHPDVCDGDHTGLLAVHSLSKTSSLAGYRAGFV
TH_1831|M.thermoresistible__bu SDECYLGLGWDETPVSVLHPTVCGGDHTNLLAIHSLSKTSSLAGYRAGFV
MSMEG_5121|M.smegmatis_MC2_155 SDECYLGLSWDADPVSVLHPSVCDGDHTGLLAIHSLSKTSSLAGYRAGFV
Mb1211|M.bovis_AF2122/97 SDECYLGLGWDAEPVSVLHPSVCDGDHTGLLAVHSLSKSSSLAGYRAGFV
Rv1178|M.tuberculosis_H37Rv SDECYLGLGWDAEPVSVLHPSVCDGDHTGLLAVHSLSKSSSLAGYRAGFV
MMAR_4273|M.marinum_M SDECYLGLAWDAQPLSVLHPAVCGGDHTGLLAVHSLSKSSSLAGYRAGFV
MUL_1026|M.ulcerans_Agy99 SDECYLGLAWDAQPLSVLHPAVCGGDHTGLLAVHSLSKSSSLAGYRAGFV
MAV_1317|M.avium_104 SDECYLGLGWDAQPLSILHPQVCDGDPTGLLAIHSLSKSSSLAGYRAGFV
MLBr_01488|M.leprae_Br4923 SDECYLGLGWDAEPFSVLHPLVCDGNHTGLLAVHSLSKSSSLAGYRAGFV
MAB_1328|M.abscessus_ATCC_1997 SDECYLGLGWDAEPVSILDPRVCDGETAGLLAVHSLSKTSSLAGYRAGFV
********.** *.*:*.* **.*: :.***:*****:***********
Mflv_2171|M.gilvum_PYR-GCK AGDPAVVAELLAVRKHAGMMVPTPIQAAMVAALDDDAHERTQRARYQRRR
Mvan_4528|M.vanbaalenii_PYR-1 AGDPAVVAELLAVRKHAGMMVPTPIQAAMVAALDDDAHEREQRERYARRR
TH_1831|M.thermoresistible__bu AGDPALVAELLAVRKHAGMMVPTPVQAAMVAALDDDAHERQQRERYQRRR
MSMEG_5121|M.smegmatis_MC2_155 AGDPAVVAELLAVRKHAGMMVPGPIQVAMVAALDDDEHEALQRDRYAQRR
Mb1211|M.bovis_AF2122/97 VGDLEIVAELLAVRKHAGMMVPAPVQAAMVAALDDDAHERQQRERYAQRR
Rv1178|M.tuberculosis_H37Rv VGDLEIVAELLAVRKHAGMMVPAPVQAAMVAALDDDAHERQQRERYAQRR
MMAR_4273|M.marinum_M AGDPELIAELLAVRRHAGMMVPTPVQAAMVAALDDDDHEKQQRERYAQRR
MUL_1026|M.ulcerans_Agy99 AGDPELIAELLAVRRHAGMMVPTPVQAAMVAALDDDDHEKQQRERYAQRR
MAV_1317|M.avium_104 AGDAELIAELLAVRKHAGMMVPTPVQAAMVAALDDDAHERAQRQRYERRR
MLBr_01488|M.leprae_Br4923 AGDPDLVAELLAVRKHAGMMVPTPVQAAMVAALGDDAHEREQRDRYARRR
MAB_1328|M.abscessus_ATCC_1997 LGDGSVVGELLAVRKHAGMMVPGPVQAAMTAALSEDEHQREQRARYEHRR
** ::.******:******* *:*.**.***.:* *: ** ** :**
Mflv_2171|M.gilvum_PYR-GCK DALLPALVSAGFTVDHSEAGLYLWATRDEPCRDTLAWLAQRGILVAPGEF
Mvan_4528|M.vanbaalenii_PYR-1 DALLPALLAAGFTVDHSEAGLYLWATRGEPCRDTVTWLAQKGILVAPGEF
TH_1831|M.thermoresistible__bu RELLPALQQAGFTVDHSEAGLYLWATRGEPCRATVDWLARRGILVAPGEF
MSMEG_5121|M.smegmatis_MC2_155 NLLLPAFREAGFTVDHSEAGLYLWATRGEACRDTLRWLAERGILVAPGEF
Mb1211|M.bovis_AF2122/97 AALLPALGSAGFAVDYSDAGLYLWATRGEPCRDSVAWLAQRGILVAPGDF
Rv1178|M.tuberculosis_H37Rv AALLPALGSAGFAVDYSDAGLYLWATRGEPCRDSAAWLAQRGILVAPGDF
MMAR_4273|M.marinum_M AVLLPALTSAGFSVDHSEAGLYLWATRGEGCRDTVAWLAERGILVAPGEF
MUL_1026|M.ulcerans_Agy99 AVLLPALTSAGFSVDHSEAGLYLWATRGEGCRDTVAWLAERGILVAPGEF
MAV_1317|M.avium_104 AALLPALRSAGFAVDHSEAGLYLWVTRGEPCRDTITWLARRGILAAPGEF
MLBr_01488|M.leprae_Br4923 DVLLPAVVSAGFTVDHSEAGLYLWASRGEPCRDSVEWFAQRGILVALGEF
MAB_1328|M.abscessus_ATCC_1997 DRLSKALTDNGFRIDHSEAGLYLWATRGDSCDDALAYLARRGILVAPGRF
* *. ** :*:*:******.:*.: * : ::*.:***.* * *
Mflv_2171|M.gilvum_PYR-GCK YGPRGTRHVRVALTATDERIDAAVERLGS---
Mvan_4528|M.vanbaalenii_PYR-1 YGPRGARHVRVALTATDERIAAAVARLADSAR
TH_1831|M.thermoresistible__bu YGPRGAEHVRIALTAPDERITAAAARLAQAG-
MSMEG_5121|M.smegmatis_MC2_155 YGPAGDRYVRVALTATDERIQQAAERLAG---
Mb1211|M.bovis_AF2122/97 YGPGGAQHVRVALTATDERVAAAVGRLTC---
Rv1178|M.tuberculosis_H37Rv YGPGGAQHVRVALTATDERVAAAVGRLTC---
MMAR_4273|M.marinum_M YGPAGAQHVRVALTATKERIAAAVRRLGEP--
MUL_1026|M.ulcerans_Agy99 YGPAGAQHVRVALTATKERIAAAVRRLGEP--
MAV_1317|M.avium_104 YGPRGAQHVRVALTADDERIAAAVRRLA----
MLBr_01488|M.leprae_Br4923 YGPGGCQHVRVALTASDERIAAVVARLS----
MAB_1328|M.abscessus_ATCC_1997 YGPRGREHVRVALTATDERIDAAAHRLTAS--
*** * .:**:**** .**: .. **