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TELHSREFALTDRYTLADGEVFLTGLQALVRIPFEQSRRDSADGQRVGILISGYEGSPLAGYDLELGRQR ELLDSHSVVFQPGLNEELAANAVQGSQLASASPSCEYDGVVGIWYGKAPGLDRATDALRHANLGGADAKG GALVLVGDDSIAKSSTVPSGSEAAMAELGLPVLVPSDPQEVLDFGLHGIAMSRFSGLWVGMKLATNVVDG SATVRFDRSRVTVQSPDREIDGAEFRHTVSAHFVQPTLGNLERSMFGERLELARRYVAANDLNRTVGDPD AKLGIITAGTGFRDTVQALQRLGIAETDLVHSGIRILKLGVINPLDQRHVQEFSEGLDEVVVVEEKRAFI ELAVKDALYGRASVPRVLGKRDEHGRRFLRADADLPPEILAEKLGQRIRKVLPANQIESVSSVERTPAGR IELPLLTRTPYFCSGCPHNRSTVVPDGSLVGAGIGCHAIATMMPHERVGEIVSLCQMGGEGAPWIGMAPF VSENHLFQNLGDGTFHHSGSLAIRAAVASGVNITYKLLYNDAVAMTGGQRAVGKMSVPQIVQELLAEGVA RIVVTTDDVKKYRKVSLPHGVAVLDRSELMSVQEELARTAGVTVLIHDQECATELRRKRKRGLAPEPVTR AFINERLCEGCGDCGQKSNCMSVQPVDTEFGRKTRIDQASCNKDYSCLDGDCPSFVAVRPGRTESSETSA TAPIPDPTPIVGTDAFNVRITGVGGTGVVTTSQIVATAGTLAGFHVRGLDQLGLAQKGGAVVSDLKFSTR PITGTNKLAAGECDLYLGCDLLVAADAKNLAVASNSRTVAVISTSQVPTGSMILKPSTAFPASAEVRERL DPSTRAHDSLYADARALAYREFGSDQLANMILVGMAVQVGSLPIPLSALEKAVELNGVAVSANLRALHVG RAYVHDPQPVNALKGVYTNHVRVARRVRRAVHELRGVDEGFRDRLGFLAADLVAYQNQSYALQFVNFVAD TAELERHAVGSVGPLTVTAAESMYKLMAYKDEYETARLFLDPGFEQSVRETFGDDASFAYKLHPPMLRAM GLDHKLTLGAWFKPALYALRTARRVRGTRLDVFGYAHVRQVERSLVDDYAKLTREVVPRATQGNIDAIRE ILGLAQEVRGYESIKMANVESYRRKVAAALDALSATAAVG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_5100 | - | - | 100% (1161) | indolepyruvate ferredoxin oxidoreductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_4433 | - | 0.0 | 45.39% (1150) | indolepyruvate ferredoxin oxidoreductase |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4356c | - | 0.0 | 54.70% (1150) | indolepyruvate ferredoxin oxidoreductase |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | - | - | - | - | - |
| M. thermoresistible (build 8) | TH_3981 | - | 1e-161 | 47.05% (644) | PUTATIVE putative pyruvate ferredoxin/flavodoxin oxidoreductase |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_5100|M.smegmatis_MC2_155 -----MTELHSREFALTDRYTLADGEVFLTGLQALVRIPFEQSRRDSADG
MAB_4356c|M.abscessus_ATCC_199 --------MRQPLVTPSERYTAVRGTVHLSGIQALVRLVLDQRRDDRRDG
TH_3981|M.thermoresistible__bu -----VIGTRLSGYRLEDRFTATTGKVLMTGVQAVCRVPLDVRRIDDRRG
Mflv_4433|M.gilvum_PYR-GCK MTDLDVRPPDPHPYDLDNRYRAGSDAVLLTGVQAIARALVEQHERDARAG
:*: . * ::*:**: * .: . * *
MSMEG_5100|M.smegmatis_MC2_155 QRVGILISGYEGSPLAGYDLELGRQRELLDSHSVVFQPGLNEELAANAVQ
MAB_4356c|M.abscessus_ATCC_199 RSTAGFISGYEGSPLAGYDTELIRNSALLDEHEIVFVPGVNEELAATAVQ
TH_3981|M.thermoresistible__bu LATRGFVTGYQGSPLGTVDFTMRDISALLDECGVDFRPGMNEMLAATSVQ
Mflv_4433|M.gilvum_PYR-GCK RRVATFVSGYQGSPLGGVDRMLYGMPDVLQAHDIVFVPGLNEELAATSVW
. :::**:****. * : :*: : * **:** ***.:*
MSMEG_5100|M.smegmatis_MC2_155 GSQLASASPSCEYDGVVGIWYGKAPGLDRATDALRHANLGGADAKGGALV
MAB_4356c|M.abscessus_ATCC_199 GTQMAVTQPDRRVDGVAAIWYGKSPGLDRAADAIRHANLMGTHPQGGVLA
TH_3981|M.thermoresistible__bu GTQTVPALGS-DLAGVTGYWYGKTPGVDQALDAIRHGNLMGTSAAGGVLA
Mflv_4433|M.gilvum_PYR-GCK GSQAELPAGTPTHDGVVGVWYGKGPGLDRATDALRHANMYGANARGGMVL
*:* . **.. **** **:*:* **:**.*: *: . ** :
MSMEG_5100|M.smegmatis_MC2_155 LVGDDSIAKSSTVPSGSEAAMAELGLPVLVPSDPQEVLDFGLHGIAMSRF
MAB_4356c|M.abscessus_ATCC_199 LVGDDPAAKSSSVPGASELLLADLGLPILYPSDPQQALDFGRHGIAMSRC
TH_3981|M.thermoresistible__bu FCGDDPNAKSSTVPGGSETVLRAALVPTLAAADPDDVLRLGLHAVAMSRA
Mflv_4433|M.gilvum_PYR-GCK LVGDDPASKSSTVPAVSERSLAALGIPVLFPRNAREIVTLFLHGVALSRA
: ***. :***:**. ** : :* * . :. : : : *.:*:**
MSMEG_5100|M.smegmatis_MC2_155 SGLWVGMKLATNVVDGSATVRFDRSRVTVQSPDREIDGAEFRHTVSAHFV
MAB_4356c|M.abscessus_ATCC_199 SGLWVAMKVVTNVADGSGTVELNPDRVRPAFPETKIDGEDYRHTVTAHML
TH_3981|M.thermoresistible__bu TGTWTALKISTHVADAYGVVTPAVETFDPVLP--LVDGKPYQHTITPAPA
Mflv_4433|M.gilvum_PYR-GCK SGCVVAVKIVADVADGAWTVDADDLDLEIVDPEVEWQGKPFVYRQRPMAA
:* ..:*: :.*.*. .* . * :* : : .
MSMEG_5100|M.smegmatis_MC2_155 QPTLGNLERSMFGERLELARRYVAANDLNR-TVGDPDAKLGIITAGTGFR
MAB_4356c|M.abscessus_ATCC_199 QPTLGALERSRDGIRLEIARKYAALNGLNQITKQAPGDRVGIVAAGKTYL
TH_3981|M.thermoresistible__bu AATAVAAEQNLHRIRLPLVVQYARLNGLNTVTAHSDRDRIGIVAAGQVYA
Mflv_4433|M.gilvum_PYR-GCK PADSLLAEADLYGPRAEMVQAYSSANRLDVVEIDPPDARIGIAAAGTTFD
. * . * :. * * *: ::** :** :
MSMEG_5100|M.smegmatis_MC2_155 DTVQALQRLGIAETD-LVHSGIRILKLGVINPLDQRHVQEFSEGLDEVVV
MAB_4356c|M.abscessus_ATCC_199 DLVQALRTLGVDN-------GVRVLRLGMIHPLEPGVIAQFAENLDYIIV
TH_3981|M.thermoresistible__bu EVRQALADLGLRTAADCAAAGVRLLKLGLVWPLEPGIVTEFADGLDEIVV
Mflv_4433|M.gilvum_PYR-GCK SLRQALTDLGADDSA-LRAAGVRLLRIGMVSPLCADTVLGFASGLDEILV
. *** ** *:*:*::*:: ** : *:..** ::*
MSMEG_5100|M.smegmatis_MC2_155 VEEKRAFIELAVKDALYGRASVPRVLGKRDEHGRRFLRADADLPPEILAE
MAB_4356c|M.abscessus_ATCC_199 VEEKRPLIELGLKDVLYGTAGAPMIYGKRNPDGNNMFPADGELDTEAIAD
TH_3981|M.thermoresistible__bu AEDKGPHLELLIKDVLYDCGCRAAVSGTTDRDGRALLPAHGGLDAEIITR
Mflv_4433|M.gilvum_PYR-GCK VEDKTAFVEAQMREILYGATNPPRMMGKKDAAGRSLIPADGELTAGRLLA
.*:* . :* ::: **. . : *. : *. :: *.. * . :
MSMEG_5100|M.smegmatis_MC2_155 KLGQRIRKVLPANQIESVSSVERTPAGRIELPLLTRTPYFCSGCPHNRST
MAB_4356c|M.abscessus_ATCC_199 QLRPVLERFGALPASE--PRIQRGRRGPVSLPLLTRTPYFCSGCPHNTST
TH_3981|M.thermoresistible__bu AVEPLLRRKGAVPRGDGAQAAPAPPRVPLSLTVANRTPYFCSGCPHNTST
Mflv_4433|M.gilvum_PYR-GCK PLRRVLGDRLELRKPP-------PPALPLEVLPTRRTAYFCSGCPHNRST
: : :.: **.********* **
MSMEG_5100|M.smegmatis_MC2_155 VVPDGSLVGAGIGCHAIATMMPHERVGEIVSLCQMGGEGAPWIGMAPFVS
MAB_4356c|M.abscessus_ATCC_199 KIPEGSMVGAGIGCHALVTMMDERQVGEVAGMTQMGGEGTQWIGMAPFLR
TH_3981|M.thermoresistible__bu RVPDGSAVGAGIGCHAMVSMMDPEHVGRITGFTQMGGEGAQWIGQQPYVH
Mflv_4433|M.gilvum_PYR-GCK AVPEGSLAGGGIGCHTMVTMSG-RADSAVTGLTQMGGEGSQWIGQAPFTD
:*:** .*.*****::.:* . . :..: ******: *** *:
MSMEG_5100|M.smegmatis_MC2_155 ENHLFQNLGDGTFHHSGSLAIRAAVASGVNITYKLLYNDAVAMTGGQRAV
MAB_4356c|M.abscessus_ATCC_199 RDHLIQNLGDGTFHHSGSLAIRAAIAAGAHITYKLLYNSAVAMTGGQQAV
TH_3981|M.thermoresistible__bu ADHVFQNLGDGTLSHSGLLAIRASIAAGTNITYKILFNSTVAMTGGQDAV
Mflv_4433|M.gilvum_PYR-GCK IAHLFQNIGDGTYFHSGQLAVQACVAAGVNITFKLLYNEVVAMTGAQHAE
*::**:**** *** **::*.:*:*.:**:*:*:*..*****.* *
MSMEG_5100|M.smegmatis_MC2_155 GKMSVPQIVQELLAEGVARIVVTTDDVKKYRKVSLPHGVAVLDRSELMSV
MAB_4356c|M.abscessus_ATCC_199 GAMSVGQICMAMLAEGVSRIIITTDNAKAYRKAKLPKGVMVWDRSRLIEA
TH_3981|M.thermoresistible__bu GGYTVTRLAETLAAEGVERIVITTDDPRRYRGHRLPRIATVEDRAELNAV
Mflv_4433|M.gilvum_PYR-GCK GALGVASLTHKLKLEGVAQVIVCADEPRRHRRRDLAAGTLLWHRDRLDEA
* * : : *** :::: :*: : :* *. . : .* .* .
MSMEG_5100|M.smegmatis_MC2_155 QEELARTAGVTVLIHDQECATELRRKRKRGLAPEPVTRAFINERLCEGCG
MAB_4356c|M.abscessus_ATCC_199 QRVLADTVGVTLLIHDQECATELRRKRKRGLVSEPAERVLINERVCEGCG
TH_3981|M.thermoresistible__bu QERLRTIPGTTVLIHDQPCAAELRRARKRGKAPTPRRRIVINERICEGCG
Mflv_4433|M.gilvum_PYR-GCK QRRLRDVPGVTVLIYDQHCAADARRQRSRGTLPSRTTRVLINEAVCEGCG
*. * *.*:**:** **:: ** *.** . * .*** :*****
MSMEG_5100|M.smegmatis_MC2_155 DCGQKSN-CMSVQPVDTEFGRKTRIDQASCNKDYSCLDGDCPSFVAVRPG
MAB_4356c|M.abscessus_ATCC_199 DCGQKSN-CLSVQPVSTEFGRKTRIDQSSCNKDLSCLEGDCPSFITVIPD
TH_3981|M.thermoresistible__bu DCGRKSNXXXRAQPR-----------------------------------
Mflv_4433|M.gilvum_PYR-GCK DCGVKSN-CLSVQPVDTEFGRKTRIDQTSCNTDYSCLDGDCPSFVTVEVT
*** *** .**
MSMEG_5100|M.smegmatis_MC2_155 ----RTESSETSATAPIPDP-TPIVGTDAFNVRITGVGGTGVVTTSQIVA
MAB_4356c|M.abscessus_ATCC_199 PNAKRLKHIPDDSLADLPDPPQLLAAAHAHTTRIAGVGGTGVVTLAQVLS
TH_3981|M.thermoresistible__bu --------------------------------------------------
Mflv_4433|M.gilvum_PYR-GCK PG--RARKPGSAPTPPPVPDVCVEPVTSTHNVLLAGIGGTGIVTANQVLA
MSMEG_5100|M.smegmatis_MC2_155 TAGTLAGFHVRGLDQLGLAQKGGAVVSDLKFSTRPITGTNKLAAGECDLY
MAB_4356c|M.abscessus_ATCC_199 VAATSSGWQVRTLDQTGLAQKGGAVVSDIKMSKAEIAEPSKAASAECDLY
TH_3981|M.thermoresistible__bu --------------------------------------------------
Mflv_4433|M.gilvum_PYR-GCK TAALRAGYDVESLDQIGLSQKAGPVVSHLRFAADRLEPANRLTPGTADCI
MSMEG_5100|M.smegmatis_MC2_155 LGCDLLVAADAKNLAVASNSRTVAVISTSQVPTGSMILKPSTAFPASAEV
MAB_4356c|M.abscessus_ATCC_199 LGCDLLVAADEKYLNAADSSRTTAVISTSEVPTGQMVIDPGVSFPEPGPL
TH_3981|M.thermoresistible__bu --------------------------------------------------
Mflv_4433|M.gilvum_PYR-GCK LAFDLLAAADEKNLGYGDPATTVSIASTSRTPTGEMVYDASVAYPDTSSL
MSMEG_5100|M.smegmatis_MC2_155 RERLDPSTRAHDSLYADARALAYREFGSDQLANMILVGMAVQVGSLPIPL
MAB_4356c|M.abscessus_ATCC_199 KALLREAVR--DTVFIDARAVSVQLLGSDQYANLLLAGAAVQLGSLPLSP
TH_3981|M.thermoresistible__bu --------------------------------------------------
Mflv_4433|M.gilvum_PYR-GCK LHRLGRASR--RVQEFDASAAAKTLFGNTAAANFLLIGAAYQAGALRIPA
MSMEG_5100|M.smegmatis_MC2_155 SALEKAVELNGVAVSANLRALHVGRAYVHDPQPVNALKG-VYTNHVRVAR
MAB_4356c|M.abscessus_ATCC_199 AAIEKAIALNGAGVQSNIAAFRYGRLAVAEPETFRRITEPPAPSSTRRSA
TH_3981|M.thermoresistible__bu --------------------------------------------------
Mflv_4433|M.gilvum_PYR-GCK AAIEEAIGINGVAVATNVAAFRWGRVAIADPAHFHDVAVPVPAGPVGTAP
MSMEG_5100|M.smegmatis_MC2_155 RVRRAVHELRGVDEGFRDRLG-FLAADLVAYQNQSYALQFVNFVADTAEL
MAB_4356c|M.abscessus_ATCC_199 AVEKLVQQVGALPGGELERLLRIRVPDLVDYQSLGYAREYVRYVADVVHM
TH_3981|M.thermoresistible__bu --------------------------------------------------
Mflv_4433|M.gilvum_PYR-GCK VHLLAGTGIS----GRVGDLIARRAADLIAFQSEAVARRYVSVLQRVWTA
MSMEG_5100|M.smegmatis_MC2_155 ERHAVGSVGPLTVTAAESMYKLMAYKDEYETARLFLDPGFEQSVRETFGD
MAB_4356c|M.abscessus_ATCC_199 ERERCAGSEALSATVARQLYKLMAYKDEYEVARLSLSPAVVAAVTAEFGE
TH_3981|M.thermoresistible__bu --------------------------------------------------
Mflv_4433|M.gilvum_PYR-GCK ER-RIGSRTEFSEAAAKGLYKFTAYKDEYEVARLLTHPRFLAQVRAEFPA
MSMEG_5100|M.smegmatis_MC2_155 DASFAYKLHPPMLRAMGLDHKLTLGAWFKPALYALRTARRVRGTRLDVFG
MAB_4356c|M.abscessus_ATCC_199 GARIAYRLHPPVLRALGLKRKLVLGPWFRPVYRILVAARRLRGTRADLFG
TH_3981|M.thermoresistible__bu --------------------------------------------------
Mflv_4433|M.gilvum_PYR-GCK GENLTYKVHPPTLRALGRRKKIGLGPRSHVVLRALAAGKRLRGTVFDPFG
MSMEG_5100|M.smegmatis_MC2_155 YAHVRQVERSLVDDYAKLTREVVPRATQGNIDAIREILGLAQEVRGYESI
MAB_4356c|M.abscessus_ATCC_199 LAKVRRCERRLVVEYKETIDTVLSELSNANLSAAVEIADLPDMVRGYESI
TH_3981|M.thermoresistible__bu --------------------------------------------------
Mflv_4433|M.gilvum_PYR-GCK YAHVRRVERRLLAEYTDLITGVADTLDEHNYDRAVQVAGLADTVRGYEGV
MSMEG_5100|M.smegmatis_MC2_155 KMANVESYRRKVAAALD-ALSATAAVG-
MAB_4356c|M.abscessus_ATCC_199 KLASVDRYRAATARAIGRFLSIGEPVPN
TH_3981|M.thermoresistible__bu ----------------------------
Mflv_4433|M.gilvum_PYR-GCK KLASVEVYRARLREMGF-----------