For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
RQPLVTPSERYTAVRGTVHLSGIQALVRLVLDQRRDDRRDGRSTAGFISGYEGSPLAGYDTELIRNSALL DEHEIVFVPGVNEELAATAVQGTQMAVTQPDRRVDGVAAIWYGKSPGLDRAADAIRHANLMGTHPQGGVL ALVGDDPAAKSSSVPGASELLLADLGLPILYPSDPQQALDFGRHGIAMSRCSGLWVAMKVVTNVADGSGT VELNPDRVRPAFPETKIDGEDYRHTVTAHMLQPTLGALERSRDGIRLEIARKYAALNGLNQITKQAPGDR VGIVAAGKTYLDLVQALRTLGVDNGVRVLRLGMIHPLEPGVIAQFAENLDYIIVVEEKRPLIELGLKDVL YGTAGAPMIYGKRNPDGNNMFPADGELDTEAIADQLRPVLERFGALPASEPRIQRGRRGPVSLPLLTRTP YFCSGCPHNTSTKIPEGSMVGAGIGCHALVTMMDERQVGEVAGMTQMGGEGTQWIGMAPFLRRDHLIQNL GDGTFHHSGSLAIRAAIAAGAHITYKLLYNSAVAMTGGQQAVGAMSVGQICMAMLAEGVSRIIITTDNAK AYRKAKLPKGVMVWDRSRLIEAQRVLADTVGVTLLIHDQECATELRRKRKRGLVSEPAERVLINERVCEG CGDCGQKSNCLSVQPVSTEFGRKTRIDQSSCNKDLSCLEGDCPSFITVIPDPNAKRLKHIPDDSLADLPD PPQLLAAAHAHTTRIAGVGGTGVVTLAQVLSVAATSSGWQVRTLDQTGLAQKGGAVVSDIKMSKAEIAEP SKAASAECDLYLGCDLLVAADEKYLNAADSSRTTAVISTSEVPTGQMVIDPGVSFPEPGPLKALLREAVR DTVFIDARAVSVQLLGSDQYANLLLAGAAVQLGSLPLSPAAIEKAIALNGAGVQSNIAAFRYGRLAVAEP ETFRRITEPPAPSSTRRSAAVEKLVQQVGALPGGELERLLRIRVPDLVDYQSLGYAREYVRYVADVVHME RERCAGSEALSATVARQLYKLMAYKDEYEVARLSLSPAVVAAVTAEFGEGARIAYRLHPPVLRALGLKRK LVLGPWFRPVYRILVAARRLRGTRADLFGLAKVRRCERRLVVEYKETIDTVLSELSNANLSAAVEIADLP DMVRGYESIKLASVDRYRAATARAIGRFLSIGEPVPN*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4356c | - | - | 100% (1158) | indolepyruvate ferredoxin oxidoreductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_4433 | - | 0.0 | 46.37% (1143) | indolepyruvate ferredoxin oxidoreductase |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_5100 | - | 0.0 | 54.70% (1150) | indolepyruvate ferredoxin oxidoreductase |
| M. thermoresistible (build 8) | TH_3981 | - | 0.0 | 51.41% (640) | PUTATIVE putative pyruvate ferredoxin/flavodoxin oxidoreductase |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_4356c|M.abscessus_ATCC_199 --------MRQPLVTPSERYTAVRGTVHLSGIQALVRLVLDQRRDDRRDG
MSMEG_5100|M.smegmatis_MC2_155 -----MTELHSREFALTDRYTLADGEVFLTGLQALVRIPFEQSRRDSADG
TH_3981|M.thermoresistible__bu -----VIGTRLSGYRLEDRFTATTGKVLMTGVQAVCRVPLDVRRIDDRRG
Mflv_4433|M.gilvum_PYR-GCK MTDLDVRPPDPHPYDLDNRYRAGSDAVLLTGVQAIARALVEQHERDARAG
:*: . * ::*:**: * .: . * *
MAB_4356c|M.abscessus_ATCC_199 RSTAGFISGYEGSPLAGYDTELIRNSALLDEHEIVFVPGVNEELAATAVQ
MSMEG_5100|M.smegmatis_MC2_155 QRVGILISGYEGSPLAGYDLELGRQRELLDSHSVVFQPGLNEELAANAVQ
TH_3981|M.thermoresistible__bu LATRGFVTGYQGSPLGTVDFTMRDISALLDECGVDFRPGMNEMLAATSVQ
Mflv_4433|M.gilvum_PYR-GCK RRVATFVSGYQGSPLGGVDRMLYGMPDVLQAHDIVFVPGLNEELAATSVW
. :::**:****. * : :*: : * **:** ***.:*
MAB_4356c|M.abscessus_ATCC_199 GTQMAVTQPDRRVDGVAAIWYGKSPGLDRAADAIRHANLMGTHPQGGVLA
MSMEG_5100|M.smegmatis_MC2_155 GSQLASASPSCEYDGVVGIWYGKAPGLDRATDALRHANLGGADAKGGALV
TH_3981|M.thermoresistible__bu GTQTVPALGS-DLAGVTGYWYGKTPGVDQALDAIRHGNLMGTSAAGGVLA
Mflv_4433|M.gilvum_PYR-GCK GSQAELPAGTPTHDGVVGVWYGKGPGLDRATDALRHANMYGANARGGMVL
*:* . **.. **** **:*:* **:**.*: *: . ** :
MAB_4356c|M.abscessus_ATCC_199 LVGDDPAAKSSSVPGASELLLADLGLPILYPSDPQQALDFGRHGIAMSRC
MSMEG_5100|M.smegmatis_MC2_155 LVGDDSIAKSSTVPSGSEAAMAELGLPVLVPSDPQEVLDFGLHGIAMSRF
TH_3981|M.thermoresistible__bu FCGDDPNAKSSTVPGGSETVLRAALVPTLAAADPDDVLRLGLHAVAMSRA
Mflv_4433|M.gilvum_PYR-GCK LVGDDPASKSSTVPAVSERSLAALGIPVLFPRNAREIVTLFLHGVALSRA
: ***. :***:**. ** : :* * . :. : : : *.:*:**
MAB_4356c|M.abscessus_ATCC_199 SGLWVAMKVVTNVADGSGTVELNPDRVRPAFPETKIDGEDYRHTVTAHML
MSMEG_5100|M.smegmatis_MC2_155 SGLWVGMKLATNVVDGSATVRFDRSRVTVQSPDREIDGAEFRHTVSAHFV
TH_3981|M.thermoresistible__bu TGTWTALKISTHVADAYGVVTPAVETFDPVLP--LVDGKPYQHTITPAPA
Mflv_4433|M.gilvum_PYR-GCK SGCVVAVKIVADVADGAWTVDADDLDLEIVDPEVEWQGKPFVYRQRPMAA
:* ..:*: :.*.*. .* . * :* : : .
MAB_4356c|M.abscessus_ATCC_199 QPTLGALERSRDGIRLEIARKYAALNGLNQITKQAPGDRVGIVAAGKTYL
MSMEG_5100|M.smegmatis_MC2_155 QPTLGNLERSMFGERLELARRYVAANDLNR-TVGDPDAKLGIITAGTGFR
TH_3981|M.thermoresistible__bu AATAVAAEQNLHRIRLPLVVQYARLNGLNTVTAHSDRDRIGIVAAGQVYA
Mflv_4433|M.gilvum_PYR-GCK PADSLLAEADLYGPRAEMVQAYSSANRLDVVEIDPPDARIGIAAAGTTFD
. * . * :. * * *: ::** :** :
MAB_4356c|M.abscessus_ATCC_199 DLVQALRTLGVDN-------GVRVLRLGMIHPLEPGVIAQFAENLDYIIV
MSMEG_5100|M.smegmatis_MC2_155 DTVQALQRLGIAETD-LVHSGIRILKLGVINPLDQRHVQEFSEGLDEVVV
TH_3981|M.thermoresistible__bu EVRQALADLGLRTAADCAAAGVRLLKLGLVWPLEPGIVTEFADGLDEIVV
Mflv_4433|M.gilvum_PYR-GCK SLRQALTDLGADDSA-LRAAGVRLLRIGMVSPLCADTVLGFASGLDEILV
. *** ** *:*:*::*:: ** : *:..** ::*
MAB_4356c|M.abscessus_ATCC_199 VEEKRPLIELGLKDVLYGTAGAPMIYGKRNPDGNNMFPADGELDTEAIAD
MSMEG_5100|M.smegmatis_MC2_155 VEEKRAFIELAVKDALYGRASVPRVLGKRDEHGRRFLRADADLPPEILAE
TH_3981|M.thermoresistible__bu AEDKGPHLELLIKDVLYDCGCRAAVSGTTDRDGRALLPAHGGLDAEIITR
Mflv_4433|M.gilvum_PYR-GCK VEDKTAFVEAQMREILYGATNPPRMMGKKDAAGRSLIPADGELTAGRLLA
.*:* . :* ::: **. . : *. : *. :: *.. * . :
MAB_4356c|M.abscessus_ATCC_199 QLRPVLERFGALPASE--PRIQRGRRGPVSLPLLTRTPYFCSGCPHNTST
MSMEG_5100|M.smegmatis_MC2_155 KLGQRIRKVLPANQIESVSSVERTPAGRIELPLLTRTPYFCSGCPHNRST
TH_3981|M.thermoresistible__bu AVEPLLRRKGAVPRGDGAQAAPAPPRVPLSLTVANRTPYFCSGCPHNTST
Mflv_4433|M.gilvum_PYR-GCK PLRRVLGDRLELRKPP-------PPALPLEVLPTRRTAYFCSGCPHNRST
: : :.: **.********* **
MAB_4356c|M.abscessus_ATCC_199 KIPEGSMVGAGIGCHALVTMMDERQVGEVAGMTQMGGEGTQWIGMAPFLR
MSMEG_5100|M.smegmatis_MC2_155 VVPDGSLVGAGIGCHAIATMMPHERVGEIVSLCQMGGEGAPWIGMAPFVS
TH_3981|M.thermoresistible__bu RVPDGSAVGAGIGCHAMVSMMDPEHVGRITGFTQMGGEGAQWIGQQPYVH
Mflv_4433|M.gilvum_PYR-GCK AVPEGSLAGGGIGCHTMVTMSG-RADSAVTGLTQMGGEGSQWIGQAPFTD
:*:** .*.*****::.:* . . :..: ******: *** *:
MAB_4356c|M.abscessus_ATCC_199 RDHLIQNLGDGTFHHSGSLAIRAAIAAGAHITYKLLYNSAVAMTGGQQAV
MSMEG_5100|M.smegmatis_MC2_155 ENHLFQNLGDGTFHHSGSLAIRAAVASGVNITYKLLYNDAVAMTGGQRAV
TH_3981|M.thermoresistible__bu ADHVFQNLGDGTLSHSGLLAIRASIAAGTNITYKILFNSTVAMTGGQDAV
Mflv_4433|M.gilvum_PYR-GCK IAHLFQNIGDGTYFHSGQLAVQACVAAGVNITFKLLYNEVVAMTGAQHAE
*::**:**** *** **::*.:*:*.:**:*:*:*..*****.* *
MAB_4356c|M.abscessus_ATCC_199 GAMSVGQICMAMLAEGVSRIIITTDNAKAYRKAKLPKGVMVWDRSRLIEA
MSMEG_5100|M.smegmatis_MC2_155 GKMSVPQIVQELLAEGVARIVVTTDDVKKYRKVSLPHGVAVLDRSELMSV
TH_3981|M.thermoresistible__bu GGYTVTRLAETLAAEGVERIVITTDDPRRYRGHRLPRIATVEDRAELNAV
Mflv_4433|M.gilvum_PYR-GCK GALGVASLTHKLKLEGVAQVIVCADEPRRHRRRDLAAGTLLWHRDRLDEA
* * : : *** :::: :*: : :* *. . : .* .* .
MAB_4356c|M.abscessus_ATCC_199 QRVLADTVGVTLLIHDQECATELRRKRKRGLVSEPAERVLINERVCEGCG
MSMEG_5100|M.smegmatis_MC2_155 QEELARTAGVTVLIHDQECATELRRKRKRGLAPEPVTRAFINERLCEGCG
TH_3981|M.thermoresistible__bu QERLRTIPGTTVLIHDQPCAAELRRARKRGKAPTPRRRIVINERICEGCG
Mflv_4433|M.gilvum_PYR-GCK QRRLRDVPGVTVLIYDQHCAADARRQRSRGTLPSRTTRVLINEAVCEGCG
*. * *.*:**:** **:: ** *.** . * .*** :*****
MAB_4356c|M.abscessus_ATCC_199 DCGQKSN-CLSVQPVSTEFGRKTRIDQSSCNKDLSCLEGDCPSFITVIPD
MSMEG_5100|M.smegmatis_MC2_155 DCGQKSN-CMSVQPVDTEFGRKTRIDQASCNKDYSCLDGDCPSFVAVRPG
TH_3981|M.thermoresistible__bu DCGRKSNXXXRAQPR-----------------------------------
Mflv_4433|M.gilvum_PYR-GCK DCGVKSN-CLSVQPVDTEFGRKTRIDQTSCNTDYSCLDGDCPSFVTVEVT
*** *** .**
MAB_4356c|M.abscessus_ATCC_199 PNAKRLKHIPDDSLADLPDPPQLLAAAHAHTTRIAGVGGTGVVTLAQVLS
MSMEG_5100|M.smegmatis_MC2_155 ----RTESSETSATAPIPDP-TPIVGTDAFNVRITGVGGTGVVTTSQIVA
TH_3981|M.thermoresistible__bu --------------------------------------------------
Mflv_4433|M.gilvum_PYR-GCK PG--RARKPGSAPTPPPVPDVCVEPVTSTHNVLLAGIGGTGIVTANQVLA
MAB_4356c|M.abscessus_ATCC_199 VAATSSGWQVRTLDQTGLAQKGGAVVSDIKMSKAEIAEPSKAASAECDLY
MSMEG_5100|M.smegmatis_MC2_155 TAGTLAGFHVRGLDQLGLAQKGGAVVSDLKFSTRPITGTNKLAAGECDLY
TH_3981|M.thermoresistible__bu --------------------------------------------------
Mflv_4433|M.gilvum_PYR-GCK TAALRAGYDVESLDQIGLSQKAGPVVSHLRFAADRLEPANRLTPGTADCI
MAB_4356c|M.abscessus_ATCC_199 LGCDLLVAADEKYLNAADSSRTTAVISTSEVPTGQMVIDPGVSFPEPGPL
MSMEG_5100|M.smegmatis_MC2_155 LGCDLLVAADAKNLAVASNSRTVAVISTSQVPTGSMILKPSTAFPASAEV
TH_3981|M.thermoresistible__bu --------------------------------------------------
Mflv_4433|M.gilvum_PYR-GCK LAFDLLAAADEKNLGYGDPATTVSIASTSRTPTGEMVYDASVAYPDTSSL
MAB_4356c|M.abscessus_ATCC_199 KALLREAVR--DTVFIDARAVSVQLLGSDQYANLLLAGAAVQLGSLPLSP
MSMEG_5100|M.smegmatis_MC2_155 RERLDPSTRAHDSLYADARALAYREFGSDQLANMILVGMAVQVGSLPIPL
TH_3981|M.thermoresistible__bu --------------------------------------------------
Mflv_4433|M.gilvum_PYR-GCK LHRLGRASR--RVQEFDASAAAKTLFGNTAAANFLLIGAAYQAGALRIPA
MAB_4356c|M.abscessus_ATCC_199 AAIEKAIALNGAGVQSNIAAFRYGRLAVAEPETFRRITEPPAPSSTRRSA
MSMEG_5100|M.smegmatis_MC2_155 SALEKAVELNGVAVSANLRALHVGRAYVHDPQPVNALKG-VYTNHVRVAR
TH_3981|M.thermoresistible__bu --------------------------------------------------
Mflv_4433|M.gilvum_PYR-GCK AAIEEAIGINGVAVATNVAAFRWGRVAIADPAHFHDVAVPVPAGPVGTAP
MAB_4356c|M.abscessus_ATCC_199 AVEKLVQQVGALPGGELERLLRIRVPDLVDYQSLGYAREYVRYVADVVHM
MSMEG_5100|M.smegmatis_MC2_155 RVRRAVHELRGVDEGFRDRLG-FLAADLVAYQNQSYALQFVNFVADTAEL
TH_3981|M.thermoresistible__bu --------------------------------------------------
Mflv_4433|M.gilvum_PYR-GCK VHLLAGTGIS----GRVGDLIARRAADLIAFQSEAVARRYVSVLQRVWTA
MAB_4356c|M.abscessus_ATCC_199 ERERCAGSEALSATVARQLYKLMAYKDEYEVARLSLSPAVVAAVTAEFGE
MSMEG_5100|M.smegmatis_MC2_155 ERHAVGSVGPLTVTAAESMYKLMAYKDEYETARLFLDPGFEQSVRETFGD
TH_3981|M.thermoresistible__bu --------------------------------------------------
Mflv_4433|M.gilvum_PYR-GCK ER-RIGSRTEFSEAAAKGLYKFTAYKDEYEVARLLTHPRFLAQVRAEFPA
MAB_4356c|M.abscessus_ATCC_199 GARIAYRLHPPVLRALGLKRKLVLGPWFRPVYRILVAARRLRGTRADLFG
MSMEG_5100|M.smegmatis_MC2_155 DASFAYKLHPPMLRAMGLDHKLTLGAWFKPALYALRTARRVRGTRLDVFG
TH_3981|M.thermoresistible__bu --------------------------------------------------
Mflv_4433|M.gilvum_PYR-GCK GENLTYKVHPPTLRALGRRKKIGLGPRSHVVLRALAAGKRLRGTVFDPFG
MAB_4356c|M.abscessus_ATCC_199 LAKVRRCERRLVVEYKETIDTVLSELSNANLSAAVEIADLPDMVRGYESI
MSMEG_5100|M.smegmatis_MC2_155 YAHVRQVERSLVDDYAKLTREVVPRATQGNIDAIREILGLAQEVRGYESI
TH_3981|M.thermoresistible__bu --------------------------------------------------
Mflv_4433|M.gilvum_PYR-GCK YAHVRRVERRLLAEYTDLITGVADTLDEHNYDRAVQVAGLADTVRGYEGV
MAB_4356c|M.abscessus_ATCC_199 KLASVDRYRAATARAIGRFLSIGEPVPN
MSMEG_5100|M.smegmatis_MC2_155 KMANVESYRRKVAAALD-ALSATAAVG-
TH_3981|M.thermoresistible__bu ----------------------------
Mflv_4433|M.gilvum_PYR-GCK KLASVEVYRARLREMGF-----------