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VSAHHIRVLDTEAELITAINVFRTAMVGFGQLTDLPPGQIRTLMEPGRTIGAFVDGQLVGTTDAQTSTLT LPGGKQLGHAAVTHVGVLPTFTRRGIATDLMRAQLHQIRDRGEAVATLRASEATIYERFGYGVASSTATI EVDVRRATLRPGVGRGGGVRLTDVGTSWALLPQIYTNNRPTRPGSIDRPEVWWHTRKLKAEAAPAPSYVA VHGDPGSETGFVRYHAVDTDSWFVSNQRTIVVDDLFAPSPEAYLALVRYLLELDLIDRVVFATLPVDDPL PELLTDRRAARITGVRDETWLRIVDVAATLDARTYSGDDAVTLRVDDPVLPENSGTYLISPDGATVTDRP AQLTAGVEALGAALLGGTPWRSLVLAGSVHADSVDAADAVDRLFAVPTAPHAGIVF
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4540 | - | - | 100% (406) | hypothetical protein MSMEG_4540 |
| M. smegmatis MC2 155 | MSMEG_3513 | - | 6e-38 | 36.94% (333) | hypothetical protein MSMEG_3513 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2439c | - | 2e-34 | 34.44% (360) | hypothetical protein Mb2439c |
| M. gilvum PYR-GCK | Mflv_0866 | - | 4e-40 | 34.10% (390) | hypothetical protein Mflv_0866 |
| M. tuberculosis H37Rv | Rv2416c | eis | 5e-35 | 34.72% (360) | hypothetical protein Rv2416c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4124 | - | 1e-90 | 48.01% (402) | hypothetical protein MAB_4124 |
| M. marinum M | MMAR_0151 | eis1 | 1e-140 | 61.19% (402) | enhanced intracellular survival protein Eis1 |
| M. avium 104 | MAV_0144 | - | 1e-140 | 61.63% (404) | hypothetical protein MAV_0144 |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_6041 | - | 7e-39 | 34.56% (379) | hypothetical protein Mvan_6041 |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0151|M.marinum_M ---------------------MSTNIRVLDTEQDLMAAGKVFRVAMVGLP
MAV_0144|M.avium_104 ---------------------MAIEIRVLEDEDDLIAAANVFRTAMVGFA
MSMEG_4540|M.smegmatis_MC2_155 --------------------MSAHHIRVLDTEAELITAINVFRTAMVGFG
MAB_4124|M.abscessus_ATCC_1997 MAFTAQPQWPGASRRNNTGQEAVTDIRFLQSRAEHERAFTVFWRAMVGLP
Mb2439c|M.bovis_AF2122/97 -------------------MPQSDSVTVTLCSPTEDDWPGMFLLAAASFT
Rv2416c|M.tuberculosis_H37Rv -------------------------MTVTLCSPTEDDWPGMFLLAAASFT
Mflv_0866|M.gilvum_PYR-GCK --------------------MPAHTTSLTVRSATETDWPAIGLIAATGFG
Mvan_6041|M.vanbaalenii_PYR-1 ----------------------------------------MALIAATGFG
: * ..:
MMAR_0151|M.marinum_M PMPNLSPGQITTLLEPGRTVGTFIDE-----QLVGTADAATSDLTLPGGA
MAV_0144|M.avium_104 PLAGLAPGQIGTLLEPGRTIGAYAGG-----QLVGTADAVTSRLTLPGGA
MSMEG_4540|M.smegmatis_MC2_155 QLTDLPPGQIRTLMEPGRTIGAFVDG-----QLVGTTDAQTSTLTLPGGK
MAB_4124|M.abscessus_ATCC_1997 ALGAVAAD---ELLELGRYLGAFVQG-----ELIGGADSYTSWLTVPGGS
Mb2439c|M.bovis_AF2122/97 DFIGPESATAWRTLVPTDGAVVVRDGAGPGSEVVGMALYMDLRLAVPGEV
Rv2416c|M.tuberculosis_H37Rv DFIGPESATAWRTLVPTDGAVVVRDGAGPGSEVVGMALYMDLRLTVPGEV
Mflv_0866|M.gilvum_PYR-GCK VWRPDETVQVWRSMMPPDSVVVACD----GDEVVGVALFLDLQLTVPGGA
Mvan_6041|M.vanbaalenii_PYR-1 VWTQQETAEAWRSLIPAGGAVVACD----GPDVVGVAVFLDLELTVPGGA
. : . :::* : *::**
MMAR_0151|M.marinum_M IVRHAAVTRIGVLPTFRRQGIATELMSHQLRDFAARGETVATLRASEATI
MAV_0144|M.avium_104 LVGHAAVTHIGVLPSFTRQGIATALVRHQLRDFAARNEVVATLRASEATI
MSMEG_4540|M.smegmatis_MC2_155 QLGHAAVTHVGVLPTFTRRGIATDLMRAQLHQIRDRGEAVATLRASEATI
MAB_4124|M.abscessus_ATCC_1997 RVPHAAVTHIGVLPTHTRRGILTALVTRQLTDIAGRGEIVASLRASEAVI
Mb2439c|M.bovis_AF2122/97 VLPTAGLSFVAVAPTHRRRGLLRAMCAELHRRIADSGYPVAALHASEGGI
Rv2416c|M.tuberculosis_H37Rv VLPTAGLSFVAVAPTHRRRGLLRAMCAELHRRIADSGYPVAALHASEGGI
Mflv_0866|M.gilvum_PYR-GCK VLPMAGVSFVAVAPTHRRRGALTAMFNELHSRMGD--YPIAGLEASEAGI
Mvan_6041|M.vanbaalenii_PYR-1 VLPMAGVSWVAVAPTHRRRGALSGMFAELHRRMDR--YPIAGLEASEAEI
: *.:: :.* *:. *:* : : :* *.***. *
MMAR_0151|M.marinum_M YERFGYGVASSAQSVEIQTARATLRPGVGTGG----PVRLLDTADSWDVL
MAV_0144|M.avium_104 YGRYGYGVASSSQSVTVHTARAALRRDVGPGG----PVRLLDTAQAWEVL
MSMEG_4540|M.smegmatis_MC2_155 YERFGYGVASSTATIEVDVRRATLRPGVGRGG----GVRLTDVGTSWALL
MAB_4124|M.abscessus_ATCC_1997 YRRFGYGIATSSATYRIQRRRAAPLRPIDTG-----AIALLDAAASPEGL
Mb2439c|M.bovis_AF2122/97 YGRFGYGPATTLHELTVDRRFARFHADAPGGGLGGSSVRLVRPTEHRGEF
Rv2416c|M.tuberculosis_H37Rv YGRFGYGPATTLHELTVDRRFARFHADAPGGGLGGSSVRLVRPTEHRGEF
Mflv_0866|M.gilvum_PYR-GCK YGRFGYGPATVWENVSVERERAQLRAGVPDP--GG--VRIVRPAEHRAQL
Mvan_6041|M.vanbaalenii_PYR-1 YGRFGYGPATIWQRLSVDRVAARFHPGVPDP--GG--VRVVRAAEHRGQI
* *:*** *: :. * : : :
MMAR_0151|M.marinum_M AGIYARNRPSRPGTIDRPGVWWQFQRLRAETSPG---PSYIAVHGEPGRE
MAV_0144|M.avium_104 PRIYAEHRPARPGTIDRPRVWWQGVRLRTESAPG---PTYVAVHGAPGSE
MSMEG_4540|M.smegmatis_MC2_155 PQIYTNNRPTRPGSIDRPEVWWHTRKLKAEAAPA---PSYVAVHGDPGSE
MAB_4124|M.abscessus_ATCC_1997 AAIYER--AAWTGSVARPPQWWRLHELFDAADPV---KPYVVTHPD----
Mb2439c|M.bovis_AF2122/97 EAIYERWRQQVPGGLLRPQVLWDELLAECKAAPGGDRESFALLHPD----
Rv2416c|M.tuberculosis_H37Rv EAIYERWRQQVPGGLLRPQVLWDELLAECKAAPGGDRESFALLHPD----
Mflv_0866|M.gilvum_PYR-GCK EDIDERWRLQTPGGLRTPARLWDEILEDRESLRGGGSALYCLLHGD----
Mvan_6041|M.vanbaalenii_PYR-1 EDVYERWRLQTPGGLHTPQVLWDEVFADRESHRDGGSAQFCLLHAD----
: . .* : * * : : *
MMAR_0151|M.marinum_M TGFVRYRPIDTEKWFVADQRTIVVEDFFAPTGAAYLGLLRFLFGLDLIDR
MAV_0144|M.avium_104 TGFVRYRPIDTERWFVSDERTIVVEDFFAPTAEAYLGLLRFLLGLDLVDR
MSMEG_4540|M.smegmatis_MC2_155 TGFVRYHAVDTDSWFVSNQRTIVVDDLFAPSPEAYLALVRYLLELDLIDR
MAB_4124|M.abscessus_ATCC_1997 -GYVRYRPQDTAEWFSSSARTISVDDLVAHSDEAYRALVGHLLDLDLVDV
Mb2439c|M.bovis_AF2122/97 -GYALYRVDRTDL------KLARVSELRAVTADAHCALWRALIGLDSMER
Rv2416c|M.tuberculosis_H37Rv -GYALYRVDRTDL------KLARVSELRAVTADAHCALWRALIGLDSMER
Mflv_0866|M.gilvum_PYR-GCK -GFAMYRVHNSERR----KDRAQVTKLAAATPQAYIALWRTLLGLDLMAT
Mvan_6041|M.vanbaalenii_PYR-1 -GFAMYRVHSADK-----KDRVEVSKLAAVTPHAYIALWRALLGLDLMAT
*:. *: : * .: * : *: .* *: ** :
MMAR_0151|M.marinum_M VVFWMLPLDDPLPWLLVDRRAMKVTAVHDETWLRVIDVRAALAARRYYGD
MAV_0144|M.avium_104 VQFWMLPLDDPLPWLLADRRAVRVTAVHDETWLRVVDARAALAARGYCSD
MSMEG_4540|M.smegmatis_MC2_155 VVFATLPVDDPLPELLTDRRAARITGVRDETWLRIVDVAATLDARTYSGD
MAB_4124|M.abscessus_ATCC_1997 IELGPRPIDDPLPHLVTDPRAVAVAGIRDETWLRLVDVEAALAARTYTDG
Mb2439c|M.bovis_AF2122/97 ISIITHPQD-PLPHLLTDTRLARTTWRQDGLWLRIMNVPAALEARGYAHE
Rv2416c|M.tuberculosis_H37Rv ISIITHPQD-PLPHLLTDTRLARTTWRQDGLWLRIMNVPAALEARGYAHE
Mflv_0866|M.gilvum_PYR-GCK VDITTHPGA-LLPYLLTDARLVRTVDVQDGLWLRMLDIPAVLQARTYDAD
Mvan_6041|M.vanbaalenii_PYR-1 VDIDTHPDN-TLPYLLTDPRLVRHPGRQDGLWLRMLDIPAVLQARSYAAD
: : * ** *:.* * :* ***::: *.* ** *
MMAR_0151|M.marinum_M G---TVTIAIDDPLLAGNSGHFTISGDG---AEPTSRRPALHLDVAGLAA
MAV_0144|M.avium_104 E---TVTVAVNDPLLQDNSVCLRIAGGG---VAVADGPADVDVDVEGLAA
MSMEG_4540|M.smegmatis_MC2_155 D---AVTLRVDDPVLPENSGTYLISPDG---ATVTDRPAQLTAGVEALGA
MAB_4124|M.abscessus_ATCC_1997 A---PVVIEVQDTLLPHNAARFSVSSDK---VRRTQHTPDISVDVAALGS
Mb2439c|M.bovis_AF2122/97 VGEFSTVLEVSD-----GGRFALKIGDGRARCTPTDAAAEIEMDRDVLGS
Rv2416c|M.tuberculosis_H37Rv VGEFSTVLEVSD-----GGRFALKIGDGRARCTPTDAAAEIEMDRDVLGS
Mflv_0866|M.gilvum_PYR-GCK L---SVALDVSDPVLDGGGRFAVEIRGGRASCVATDAPADVHTDLSVLGS
Mvan_6041|M.vanbaalenii_PYR-1 L---SVVLEVSDDILGGGGRFALQVRDGRARCAPTDAEADVHLDLSVLGS
...: :.* .. . :. . : . *.:
MMAR_0151|M.marinum_M VLLGGARWRDLAMAGLARCEDPTALAVADQLFAAPEAPHAGFFF
MAV_0144|M.avium_104 VLLGGTTWRDLAVAGLARARDPGALAVADRLFAVPEAPHAGFFF
MSMEG_4540|M.smegmatis_MC2_155 ALLGGTPWRSLVLAGSVHADSVDAADAVDRLFAVPTAPHAGIVF
MAB_4124|M.abscessus_ATCC_1997 VYLGGNTWTRLERAGLVSAQSPGAIRAADALFSTGTQPFAGTNF
Mb2439c|M.bovis_AF2122/97 LYLGAHRASTLAAANRLRTKDSQLLRRLDAAFASDVPVQTAFEF
Rv2416c|M.tuberculosis_H37Rv LYLGAHRASTLAAANRLRTKDSQLLRRLDAAFASDVPVQTAFEF
Mflv_0866|M.gilvum_PYR-GCK LYLGAHRASAFAAAHRLRCEDSTQLRALDAAFATDIPAELGYGF
Mvan_6041|M.vanbaalenii_PYR-1 LYLGAHRASPFAAAHRLRCS-AERARQLDAAFATDGPAELGYGF
**. : * * *: . *