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ITPRTLHTITDDDWTRIALLARFAFGDIEPEQTQAAWRSMVPEDATVVVPDETDDAFVGQSLYLDMQLTV PGGEVLPVAGISFVAVAPTHRRRGVLRAMYTELHDRIARAGYPLAVLTASEGGIYGRFGYGVATIEQHVS VDRRLAQFHPAAPDPGGVRMLVPADHRDGLADIYDRWRRRTPGGLVRPDALWDDLLADRPESRRGGGELF AFGHQDGYALYRVDRGPDGRRSAHVVELTAVTADAHAALWRALLGLDLIDRVSIGTHPHDPLPYLLTDPR QAQVTASADDLWIRIMNVPAALEARRYQADLDVVLDVADGFRSDGGRFALQISGGRARCTTTDAPADIEI DLDVLGGLYLGAHRVDGFAAANRLRSKDSELLQQFGAAFAGDMPAELGYGF*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3513 | - | - | 100% (402) | hypothetical protein MSMEG_3513 |
| M. smegmatis MC2 155 | MSMEG_4540 | - | 6e-38 | 36.94% (333) | hypothetical protein MSMEG_4540 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2439c | - | 1e-122 | 57.39% (406) | hypothetical protein Mb2439c |
| M. gilvum PYR-GCK | Mflv_0866 | - | 1e-122 | 55.50% (400) | hypothetical protein Mflv_0866 |
| M. tuberculosis H37Rv | Rv2416c | eis | 1e-123 | 57.64% (406) | hypothetical protein Rv2416c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4124 | - | 3e-40 | 37.50% (304) | hypothetical protein MAB_4124 |
| M. marinum M | MMAR_3740 | eis | 1e-115 | 54.66% (397) | enhanced intracellular survival protein Eis |
| M. avium 104 | MAV_1658 | - | 3e-59 | 36.64% (393) | hypothetical protein MAV_1658 |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_6041 | - | 1e-116 | 55.84% (385) | hypothetical protein Mvan_6041 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2439c|M.bovis_AF2122/97 -MPQSDSVTVTLCSPTEDDWPGMFLLAAASFTDFIGPESATAWRTLVPTD
Rv2416c|M.tuberculosis_H37Rv -------MTVTLCSPTEDDWPGMFLLAAASFTDFIGPESATAWRTLVPTD
MMAR_3740|M.marinum_M -MTAVLPASVTLTTPAEDDWAGMYLLAAASFTDFIGAESADAWRGLIPAD
Mflv_0866|M.gilvum_PYR-GCK --MPAHTTSLTVRSATETDWPAIGLIAATGFGVWRPDETVQVWRSMMPPD
Mvan_6041|M.vanbaalenii_PYR-1 ----------------------MALIAATGFGVWTQQETAEAWRSLIPAG
MSMEG_3513|M.smegmatis_MC2_155 -----MITPRTLHTITDDDWTRIALLARFAFGDIEPEQTQAAWRSMVPED
MAV_1658|M.avium_104 --MNTHDDGIAIRHPTEDDWQAVFENQARTFGDPVGPQDLEAWKRRVRLD
MAB_4124|M.abscessus_ATCC_1997 MAFTAQPQWPGASRRNNTGQEAVTDIRFLQSRAEHERAFTVFWRAMVGLP
: *: :
Mb2439c|M.bovis_AF2122/97 GA-VVVRDGAGP---------GSEVVGMALYMDLRLAVPGEVVLPTAGLS
Rv2416c|M.tuberculosis_H37Rv GA-VVVRDGAGP---------GSEVVGMALYMDLRLTVPGEVVLPTAGLS
MMAR_3740|M.marinum_M GA-VVARHGR-------------DVVGMALFIDLQLTVPGGNVLSTAGMS
Mflv_0866|M.gilvum_PYR-GCK SV-VVACDGD-------------EVVGVALFLDLQLTVPGGAVLPMAGVS
Mvan_6041|M.vanbaalenii_PYR-1 GA-VVACDGP-------------DVVGVAVFLDLELTVPGGAVLPMAGVS
MSMEG_3513|M.smegmatis_MC2_155 AT-VVVPDET-----------DDAFVGQSLYLDMQLTVPGGEVLPVAGIS
MAV_1658|M.avium_104 DI-LIAEDVSDPK--------NPFLVGTSIIYPAQLTVPGGANLRAAWLT
MAB_4124|M.abscessus_ATCC_1997 ALGAVAADELLELGRYLGAFVQGELIGGADSYTSWLTVPGGSRVPHAAVT
:. . .:* : *:*** : * ::
Mb2439c|M.bovis_AF2122/97 FVAVAPTHRRRGLLRAMCAELHRRIADSGYPVAALHASEGGIYGRFGYGP
Rv2416c|M.tuberculosis_H37Rv FVAVAPTHRRRGLLRAMCAELHRRIADSGYPVAALHASEGGIYGRFGYGP
MMAR_3740|M.marinum_M FVAVAPTHRRRGLLRAMCGELHRRMADSGYAMAALHASEGGIYGRFGYGP
Mflv_0866|M.gilvum_PYR-GCK FVAVAPTHRRRGALTAMFNELHSRMGD--YPIAGLEASEAGIYGRFGYGP
Mvan_6041|M.vanbaalenii_PYR-1 WVAVAPTHRRRGALSGMFAELHRRMDR--YPIAGLEASEAEIYGRFGYGP
MSMEG_3513|M.smegmatis_MC2_155 FVAVAPTHRRRGVLRAMYTELHDRIARAGYPLAVLTASEGGIYGRFGYGV
MAV_1658|M.avium_104 MIAVASTHQGKGLWAQLSAKGLGILLDRGYPLVCGVPTQTAMYDGFGAGV
MAB_4124|M.abscessus_ATCC_1997 HIGVLPTHTRRGILTALVTRQLTDIAGRGEIVASLRASEAVIYRRFGYGI
:.* .** :* : . : :. .:: :* ** *
Mb2439c|M.bovis_AF2122/97 ATTLHELTVDRRFARFHADAPGGGLGGSSVRLVRPTEHRGEFEAIYERWR
Rv2416c|M.tuberculosis_H37Rv ATTLHELTVDRRFARFHADAPGGGLGGSSVRLVRPTEHRGEFEAIYERWR
MMAR_3740|M.marinum_M ATILQQLTVDRRFARLHAGVPDGGP----VRLVSPARHRAEFEAIYERWR
Mflv_0866|M.gilvum_PYR-GCK ATVWENVSVERERAQLRAGVPDPGG----VRIVRPAEHRAQLEDIDERWR
Mvan_6041|M.vanbaalenii_PYR-1 ATIWQRLSVDRVAARFHPGVPDPGG----VRVVRAAEHRGQIEDVYERWR
MSMEG_3513|M.smegmatis_MC2_155 ATIEQHVSVDRRLAQFHPAAPDPGG----VRMLVPADHRDGLADIYDRWR
MAV_1658|M.avium_104 SSYSHTYAIDRRFAKLRDAPGDDRA-----REVNAATARRHLPGLYERWW
MAB_4124|M.abscessus_ATCC_1997 ATSSATYRIQRRRAAPLRPIDTGAI-----ALLDAAASPEGLAAIYER--
:: ::* * : .: : : :*
Mb2439c|M.bovis_AF2122/97 QQVPGGLLRPQVLWDELLAECKAAPGGDRESFALLHPDGYALYRVDRTDL
Rv2416c|M.tuberculosis_H37Rv QQVPGGLLRPQVLWDELLAECKAAPGGDRESFALLHPDGYALYRVDRTDL
MMAR_3740|M.marinum_M QRVPGGLVRPPVFWDQLMAECKASPGGERESFALLHADGYALYRADRSDP
Mflv_0866|M.gilvum_PYR-GCK LQTPGGLRTPARLWDEILEDRESLRGGGSALYCLLHGDGFAMYRVHNSER
Mvan_6041|M.vanbaalenii_PYR-1 LQTPGGLHTPQVLWDEVFADRESHRDGGSAQFCLLHADGFAMYRVHSADK
MSMEG_3513|M.smegmatis_MC2_155 RRTPGGLVRPDALWDDLLADRPESRRGGGELFAFGHQDGYALYRVDRGPD
MAV_1658|M.avium_104 AVTPGAVTRDKAWWADHLEDRTTQRGNGSALHYTIHPDGFLTYRVVGSRQ
MAB_4124|M.abscessus_ATCC_1997 AAWTGSVARPPQWWRLHELFDAADP---VKPYVVTHPDGYVRYRPQDTAE
.*.: * . * **: **
Mb2439c|M.bovis_AF2122/97 -------KLARVSELRAVTADAHCALWRALIGLDSMERISIITHP-QDPL
Rv2416c|M.tuberculosis_H37Rv -------KLARVSELRAVTADAHCALWRALIGLDSMERISIITHP-QDPL
MMAR_3740|M.marinum_M -------KLTRVDELRAVTPEARAALWRTLFGLDSMERVSIVSHP-AEPM
Mflv_0866|M.gilvum_PYR-GCK R-----KDRAQVTKLAAATPQAYIALWRTLLGLDLMATVDITTHP-GALL
Mvan_6041|M.vanbaalenii_PYR-1 ------KDRVEVSKLAAVTPHAYIALWRALLGLDLMATVDIDTHP-DNTL
MSMEG_3513|M.smegmatis_MC2_155 G-----RRSAHVVELTAVTADAHAALWRALLGLDLIDRVSIGTHP-HDPL
MAV_1658|M.avium_104 HAFRPPLGTVVVEDFCPITDEAHTELLQTLLVLEMFYRVEIDVPP-DDPL
MAB_4124|M.abscessus_ATCC_1997 WFS-SSARTISVDDLVAHSDEAYRALVGHLLDLDLVDVIELGPRPIDDPL
* .: . : .* * *: *: . :.: * :
Mb2439c|M.bovis_AF2122/97 PHLLTDTRLARTTWRQDGLWLRIMNVPAALEARGYAHEVGEFSTVLEVSD
Rv2416c|M.tuberculosis_H37Rv PHLLTDTRLARTTWRQDGLWLRIMNVPAALEARGYAHEVGEFSTVLEVSD
MMAR_3740|M.marinum_M PFLLTNTRLARTTWRQDGLWLRIMDVVPALEARAY---FGDLTTVIAITG
Mflv_0866|M.gilvum_PYR-GCK PYLLTDARLVRTVDVQDGLWLRMLDIPAVLQARTY---DADLSVALDVSD
Mvan_6041|M.vanbaalenii_PYR-1 PYLLTDPRLVRHPGRQDGLWLRMLDIPAVLQARSY---AADLSVVLEVSD
MSMEG_3513|M.smegmatis_MC2_155 PYLLTDPRQAQVTASADDLWIRIMNVPAALEARRY---QADLDVVLDVAD
MAV_1658|M.avium_104 PLKLVDQRAAETKGISDFLWVRINDVPEVLGARGY---AADTDIVLDVTD
MAB_4124|M.abscessus_ATCC_1997 PHLVTDPRAVAVAGIRDETWLRLVDVEAALAARTY---TDGAPVVIEVQD
* :.: * . * *:*: :: .* ** * .: : .
Mb2439c|M.bovis_AF2122/97 -----GGRFALKIGDGRARCTPTDAAAEIEMDRDVLGSLYLGAHRASTLA
Rv2416c|M.tuberculosis_H37Rv -----GGRFALKIGDGRARCTPTDAAAEIEMDRDVLGSLYLGAHRASTLA
MMAR_3740|M.marinum_M -----GGRFALQIRDGRAACTPTDAPADVEMDRDVLGSLYLGAHRASTLA
Mflv_0866|M.gilvum_PYR-GCK PVLDGGGRFAVEIRGGRASCVATDAPADVHTDLSVLGSLYLGAHRASAFA
Mvan_6041|M.vanbaalenii_PYR-1 DILGGGGRFALQVRDGRARCAPTDAEADVHLDLSVLGSLYLGAHRASPFA
MSMEG_3513|M.smegmatis_MC2_155 GFRSDGGRFALQISGGRARCTTTDAPADIEIDLDVLGGLYLGAHRVDGFA
MAV_1658|M.avium_104 PLGLAGGRFQLQTRDGAGKCTPHDGPADLEIGLADLATVYMGAHRGAQLA
MAB_4124|M.abscessus_ATCC_1997 TLLP---HNAARFSVSSDKVRRTQHTPDISVDVAALGSVYLGGNTWTRLE
: . . : .:: . *. :*:*.: :
Mb2439c|M.bovis_AF2122/97 AANRLRTKDSQLLRRLDAAFASDVPVQTAFEF
Rv2416c|M.tuberculosis_H37Rv AANRLRTKDSQLLRRLDAAFASDVPVQTAFEF
MMAR_3740|M.marinum_M AANRLQAKDVGVIARLDAAFSSEVPAETAFEF
Mflv_0866|M.gilvum_PYR-GCK AAHRLRCEDSTQLRALDAAFATDIPAELGYGF
Mvan_6041|M.vanbaalenii_PYR-1 AAHRLRCS-AERARQLDAAFATDGPAELGYGF
MSMEG_3513|M.smegmatis_MC2_155 AANRLRSKDSELLQQFGAAFAGDMPAELGYGF
MAV_1658|M.avium_104 RAKRITELRQGALGRLDAAFGAERAPFCGTVL
MAB_4124|M.abscessus_ATCC_1997 RAGLVSAQSPGAIRAADALFSTGTQPFAGTNF
* : .* *. . :