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SAPGGQRKPVVLLRPVPGDSVIHQLWAGTKLLSVAVIGIMLTFYPGWVPIGFTAVLVLVVARLARIPRGV VPTIPWWMWLLVAFGALTATFAGGSPEFDVGSMTIGLGGLLNFLRITALSIVLLGLGALVSWTTNVADIA PAVATLGRPLGVFRIPVHDWAVTIALALRAFPMLIDEFRTLYAARRLRPRERPDTFRARHRQRVSGVVDL IAAAVTVALRRGDEMGDAITARGGTGQFSAAESKPRRLDWVAFAVLAVVCGTALALELTVLGTSLPRRRG *
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4469 | - | - | 100% (281) | cobalt transport protein |
| M. smegmatis MC2 155 | MSMEG_2609 | cbiQ | 5e-06 | 23.94% (259) | cobalt ABC transporter, permease protein CbiQ |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2352c | - | 5e-97 | 63.64% (264) | hypothetical protein Mb2352c |
| M. gilvum PYR-GCK | Mflv_2731 | - | 1e-112 | 71.63% (282) | cobalt transport protein |
| M. tuberculosis H37Rv | Rv2325c | - | 5e-97 | 63.64% (264) | hypothetical protein Rv2325c |
| M. leprae Br4923 | MLBr_00849 | - | 3e-93 | 60.66% (272) | hypothetical protein MLBr_00849 |
| M. abscessus ATCC 19977 | MAB_1714 | - | 1e-79 | 57.46% (268) | hypothetical protein MAB_1714 |
| M. marinum M | MMAR_3625 | - | 4e-95 | 65.77% (260) | hypothetical protein MMAR_3625 |
| M. avium 104 | MAV_3956 | - | 3e-95 | 61.34% (269) | cobalt transport protein, putative |
| M. thermoresistible (build 8) | TH_0731 | - | 7e-35 | 78.02% (91) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_1240 | - | 8e-95 | 65.38% (260) | hypothetical protein MUL_1240 |
| M. vanbaalenii PYR-1 | Mvan_3805 | - | 1e-111 | 71.58% (278) | cobalt transport protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2731|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3805|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_4469|M.smegmatis_MC2_155 --------------------------------------------------
TH_0731|M.thermoresistible__bu --------------------------------------------------
MAV_3956|M.avium_104 MAGLTVPTTGTCLLDGRPAAEQVGAVALQFQAARLQLMRSRVDLEVASAA
MMAR_3625|M.marinum_M --------------------------------------------------
MUL_1240|M.ulcerans_Agy99 --------------------------------------------------
Mb2352c|M.bovis_AF2122/97 --------------------------------------------------
Rv2325c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00849|M.leprae_Br4923 --------------------------------------------------
MAB_1714|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_2731|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3805|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_4469|M.smegmatis_MC2_155 --------------------------------------------------
TH_0731|M.thermoresistible__bu --------------------------------------------------
MAV_3956|M.avium_104 GFSPDDHDRVSAALATVGLDAGLAERRIDQLSGGQMRRVVLAGLLARSPR
MMAR_3625|M.marinum_M --------------------------------------------------
MUL_1240|M.ulcerans_Agy99 --------------------------------------------------
Mb2352c|M.bovis_AF2122/97 --------------------------------------------------
Rv2325c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00849|M.leprae_Br4923 --------------------------------------------------
MAB_1714|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_2731|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3805|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_4469|M.smegmatis_MC2_155 --------------------------------------------------
TH_0731|M.thermoresistible__bu --------------------------------------------------
MAV_3956|M.avium_104 VLILDEPLAGLDAASQRGLVELLAERRRETGLTVVVISHDFAGLEQLCPR
MMAR_3625|M.marinum_M --------------------------------------------------
MUL_1240|M.ulcerans_Agy99 --------------------------------------------------
Mb2352c|M.bovis_AF2122/97 --------------------------------------------------
Rv2325c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00849|M.leprae_Br4923 --------------------------------------------------
MAB_1714|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_2731|M.gilvum_PYR-GCK -----------------------MTAAGTPRKPRRQVVLLRPVPGRTPMH
Mvan_3805|M.vanbaalenii_PYR-1 -----------------------MTAAAAPRKPRRQVVVLRPVPGDTVIH
MSMEG_4469|M.smegmatis_MC2_155 -----------------------MSAPGGQRKP---VVLLRPVPGDSVIH
TH_0731|M.thermoresistible__bu --------------------------------------------------
MAV_3956|M.avium_104 ILHLRDGSLDANPVAAQPVPVPVAPPTKRPAARRRPVVLLRPVPGSSPIH
MMAR_3625|M.marinum_M --------------MTVSSPSASATPERGSRRAARPVVLLVPVPRGSAIH
MUL_1240|M.ulcerans_Agy99 --------------MTVSSPSASATPERGSRRATRPVVLLVPAPRGSAIH
Mb2352c|M.bovis_AF2122/97 --------------MTTTS----APARNGTRRPSRPIVLLIPVPGSSVIH
Rv2325c|M.tuberculosis_H37Rv --------------MTTTS----APARNGTRRPSRPIVLLIPVPGSSVIH
MLBr_00849|M.leprae_Br4923 --------------MTSLS----MSEHHVPRRRSRPVVLLVPVPGTSTIH
MAB_1714|M.abscessus_ATCC_1997 --------------------------MTKTRAPRRPVVLLRPVPGTSTIH
Mflv_2731|M.gilvum_PYR-GCK DLWAGSKLIIVAAIGVLLTFYPGWVPIAAVALLVVIAARIARIPRGVLPS
Mvan_3805|M.vanbaalenii_PYR-1 RLWAGSKLLIVAGIGVLLTFYPGWVPIGAVALLVVVTARMARIPRGVLPT
MSMEG_4469|M.smegmatis_MC2_155 QLWAGTKLLSVAVIGIMLTFYPGWVPIGFTAVLVLVVARLARIPRGVVPT
TH_0731|M.thermoresistible__bu --------------------------------------------------
MAV_3956|M.avium_104 ELWAGTKLLVVFAMSLLLTVFPGWVAIGLATALAAAGLRLAHIPRGVLPS
MMAR_3625|M.marinum_M DLWAGTKLLVVFAISVLLTFYPGWVTIGLMAALVLVAAWIAHIPRGAVPS
MUL_1240|M.ulcerans_Agy99 DLWAGTKLLVVFAISVLLTFYPGWVTIGLMAALVLVAAWIAHIPRGAVPS
Mb2352c|M.bovis_AF2122/97 DLWAGTKLLVVFGISVLLTFYPGWVTIGMMAALVLAAARIAHIPRGALPS
Rv2325c|M.tuberculosis_H37Rv DLWAGTKLLVVFGISVLLTFYPGWVTIGMMAALVLAAARIAHIPRGALPS
MLBr_00849|M.leprae_Br4923 DLWAGTKLLVVFGVEVLLTFYPGWVTIGLVAALVCGAAWIARIPRDVLPS
MAB_1714|M.abscessus_ATCC_1997 ELWAGTKLIAVFLISVLLTFFPTWTAIGAVAALVILTAWLAHIPRGAVPT
Mflv_2731|M.gilvum_PYR-GCK IPGWLWFLLLLGAVTATFAGGTPEFSVGSMTVGLGGLLNFLRITALSIVL
Mvan_3805|M.vanbaalenii_PYR-1 IPAWLWFLLLLGAVTAAFAGGDPVIGVGSVEVGLGGLLNFLRITALATVL
MSMEG_4469|M.smegmatis_MC2_155 IPWWMWLLVAFGALTATFAGGSPEFDVGSMTIGLGGLLNFLRITALSIVL
TH_0731|M.thermoresistible__bu --------------------------VAGTELGLGGLLNFLRITALSIVL
MAV_3956|M.avium_104 VPRWLWIFLGVVGVTAALAGGAPTIHLGTASLGLGGLLDFLRATALTVVL
MMAR_3625|M.marinum_M MPRWLFVVLAFGGLTAALAGGDPMVSVGGVELGLGGALNFLRITALSIVL
MUL_1240|M.ulcerans_Agy99 MPRWLFVVLAFGGLTAALAGGDPMVSVGGVELGLGGALNFLRITALSIVL
Mb2352c|M.bovis_AF2122/97 VPRWLWIVLAIGFLTAALAGGTPVVAVGGVQLGLGGALHFLRITALSVVL
Rv2325c|M.tuberculosis_H37Rv VPRWLWIVLAIGFLTAALAGGTPVVAVGGVQLGLGGALHFLRITALSVVL
MLBr_00849|M.leprae_Br4923 MPRWLWIVVVLGGFTAALAGGSPVVSMGGVDIGLGGVLNFLRITAWSVVL
MAB_1714|M.abscessus_ATCC_1997 IPIWMVALVIGGSLTVFFSGGPPFWHIGGLTIGFHGVLAVARTTAVAAVL
:. :*: * * . * ** : **
Mflv_2731|M.gilvum_PYR-GCK LGLGAMVSWTTNVAEVAPAVAKLGRPLRPLRIPVDEWAVTIALALRAFPM
Mvan_3805|M.vanbaalenii_PYR-1 LGLGAMVSWTTNVAEVAPAVARLGRPLRPLRIPVDDWAVTLALALRAFPM
MSMEG_4469|M.smegmatis_MC2_155 LGLGALVSWTTNVADIAPAVATLGRPLGVFRIPVHDWAVTIALALRAFPM
TH_0731|M.thermoresistible__bu LALGALISWTTNVAEIAPAVAALGRPLRWLRIPIDDWAVSLALALRAFPM
MAV_3956|M.avium_104 LGLGALVSWTTNVAQIAPAVAALGRPLRVLRIPVDDWSVALALALRTFPM
MMAR_3625|M.marinum_M LALGAMVSWTTNVAEIGPAVATLGRPLRLLRIPVDEWAVVLALALRAFPM
MUL_1240|M.ulcerans_Agy99 LALGAMVSWTTNVAEIGPAVATLGRPLRLLRIPVDEWAVVLALALRAFPM
Mb2352c|M.bovis_AF2122/97 LALGAMVSWTTNVAEISPAVATLGRPFRVLRIPVDEWAVALALALRAFPM
Rv2325c|M.tuberculosis_H37Rv LALGAMVSWTTNVAEISPAVATLGRPFRVLRIPVDEWAVALALALRAFPM
MLBr_00849|M.leprae_Br4923 LGLGAMVSWTTNVAEIGPAMATLGRPLRIFRIPVDEWAVAVALALRAFPM
MAB_1714|M.abscessus_ATCC_1997 LGTGAMVSWTTNVSEIAPAVAVLGRPLKVFGIPVDERAATLALALRSFPM
*. **::******:::.**:* ****: : **:.: :. :*****:***
Mflv_2731|M.gilvum_PYR-GCK LIDEFSVLYAARRLRPGDVDARRRARV-RQWASEVIDMLAAAVTVALRRA
Mvan_3805|M.vanbaalenii_PYR-1 LIDEFSVLYAARRLRPREVDGNRRTKL-RRWAAEVIDLLAAAITVSLRRA
MSMEG_4469|M.smegmatis_MC2_155 LIDEFRTLYAARRLRPRERPDTFRARH-RQRVSGVVDLIAAAVTVALRRG
TH_0731|M.thermoresistible__bu LIDEFRILYAARRMX------TRR--------------------------
MAV_3956|M.avium_104 LIDEFRVLYAARRLRPRRPAQTRWARL-RRPATDLIDVVVAVITVTLRRA
MMAR_3625|M.marinum_M LIDEFQVLYAARRLRPRPMPVTRKARR-QRRGMEVIDLLAAAITVTLRRA
MUL_1240|M.ulcerans_Agy99 LIDEFQVLYAARRLRPRPMPVTRKARR-QRRGMEVIDLLAAAITVTLRRA
Mb2352c|M.bovis_AF2122/97 LIDEFQVLYAARRLRPKRMPPSRKARR-QRHARELIDLLAAAITVTLRRA
Rv2325c|M.tuberculosis_H37Rv LIDEFQVLYAARRLRPKRMPPSRKARR-QRHARELIDLLAAAITVTLRRA
MLBr_00849|M.leprae_Br4923 LINEFQVLYAARRLRPKQILNSRKARR-QRQARELIDLLAAAITVTLRRA
MAB_1714|M.abscessus_ATCC_1997 LSDEFRVLIAARRLRPPQVREGRRGRRGLRWIAEAVDMLTAAITAALRRA
* :** * ****:
Mflv_2731|M.gilvum_PYR-GCK DEMGDAITARGGAGQISAVPSGPKRRDWIAFAVVLAVCGVALALELTILG
Mvan_3805|M.vanbaalenii_PYR-1 DEMGDAITARGGAGQISAAPSGPRRRDWVAFSVVILVCGAALALELTVLG
MSMEG_4469|M.smegmatis_MC2_155 DEMGDAITARGGTGQFSAAESKPRRLDWVAFAVLAVVCGTALALELTVLG
TH_0731|M.thermoresistible__bu --------------------------------------------------
MAV_3956|M.avium_104 DEMGDAITARGGTGQISAAPSRPKRNDWIALSIASAVCAAAVAAELALLA
MMAR_3625|M.marinum_M DEMGDAITARGGTGQLSANPTRPKLGDWVTLAITAATSGAAVVIETMLHA
MUL_1240|M.ulcerans_Agy99 DEMGDAITARGGTGQLSANPTRPKLGDWVTLAITAATSGAAVVIETMLHA
Mb2352c|M.bovis_AF2122/97 DEMGDAITARGGTGQLSAHPGRPKLADWVTLAITAMASGTAVAIESLILH
Rv2325c|M.tuberculosis_H37Rv DEMGDAITARGGTGQLSAHPGRPKLADWVTLAITAMASGTAVAIESLILH
MLBr_00849|M.leprae_Br4923 DEMGDAITARGGIGQLSAYPARPKLADWVTLAITITTSSTAVVLETILHT
MAB_1714|M.abscessus_ATCC_1997 SEMGDAITARGGTGQISAHPARPGLNDAIALLLVIAVGTAVVLFEVL---
Mflv_2731|M.gilvum_PYR-GCK TSGTQR--
Mvan_3805|M.vanbaalenii_PYR-1 TSGIRR--
MSMEG_4469|M.smegmatis_MC2_155 TSLPRRRG
TH_0731|M.thermoresistible__bu --------
MAV_3956|M.avium_104 GH------
MMAR_3625|M.marinum_M A-------
MUL_1240|M.ulcerans_Agy99 A-------
Mb2352c|M.bovis_AF2122/97 S-------
Rv2325c|M.tuberculosis_H37Rv S-------
MLBr_00849|M.leprae_Br4923 AS------
MAB_1714|M.abscessus_ATCC_1997 --------