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MAGLTVPTTGTCLLDGRPAAEQVGAVALQFQAARLQLMRSRVDLEVASAAGFSPDDHDRVSAALATVGLD AGLAERRIDQLSGGQMRRVVLAGLLARSPRVLILDEPLAGLDAASQRGLVELLAERRRETGLTVVVISHD FAGLEQLCPRILHLRDGSLDANPVAAQPVPVPVAPPTKRPAARRRPVVLLRPVPGSSPIHELWAGTKLLV VFAMSLLLTVFPGWVAIGLATALAAAGLRLAHIPRGVLPSVPRWLWIFLGVVGVTAALAGGAPTIHLGTA SLGLGGLLDFLRATALTVVLLGLGALVSWTTNVAQIAPAVAALGRPLRVLRIPVDDWSVALALALRTFPM LIDEFRVLYAARRLRPRRPAQTRWARLRRPATDLIDVVVAVITVTLRRADEMGDAITARGGTGQISAAPS RPKRNDWIALSIASAVCAAAVAAELALLAGH
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_3956 | - | - | 100% (451) | cobalt transport protein, putative |
| M. avium 104 | MAV_2083 | - | 3e-96 | 64.93% (268) | cobalt transport protein |
| M. avium 104 | MAV_2082 | - | 2e-63 | 71.76% (170) | ABC transporter |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2352c | - | 1e-102 | 67.51% (277) | hypothetical protein Mb2352c |
| M. gilvum PYR-GCK | Mflv_2731 | - | 2e-96 | 63.57% (269) | cobalt transport protein |
| M. tuberculosis H37Rv | Rv2325c | - | 1e-102 | 67.51% (277) | hypothetical protein Rv2325c |
| M. leprae Br4923 | MLBr_00849 | - | 2e-97 | 64.55% (268) | hypothetical protein MLBr_00849 |
| M. abscessus ATCC 19977 | MAB_1714 | - | 2e-77 | 57.74% (265) | hypothetical protein MAB_1714 |
| M. marinum M | MMAR_3625 | - | 1e-98 | 65.02% (283) | hypothetical protein MMAR_3625 |
| M. smegmatis MC2 155 | MSMEG_4469 | - | 8e-95 | 61.34% (269) | cobalt transport protein |
| M. thermoresistible (build 8) | TH_0730 | - | 8e-58 | 73.89% (157) | POSSIBLE TRANSMEMBRANE ATP-BINDING PROTEIN ABC TRANSORTER |
| M. ulcerans Agy99 | MUL_1240 | - | 2e-98 | 64.66% (283) | hypothetical protein MUL_1240 |
| M. vanbaalenii PYR-1 | Mvan_3805 | - | 1e-97 | 65.43% (269) | cobalt transport protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2352c|M.bovis_AF2122/97 --------------------------------------------------
Rv2325c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3625|M.marinum_M --------------------------------------------------
MUL_1240|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00849|M.leprae_Br4923 --------------------------------------------------
MAB_1714|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_2731|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3805|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_4469|M.smegmatis_MC2_155 --------------------------------------------------
MAV_3956|M.avium_104 MAGLTVPTTGTCLLDGRPAAEQVGAVALQFQAARLQLMRSRVDLEVASAA
TH_0730|M.thermoresistible__bu -----------------------MTMTGQARRPHRAGSLHPVELAHASVM
Mb2352c|M.bovis_AF2122/97 --------------------------------------------------
Rv2325c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3625|M.marinum_M --------------------------------------------------
MUL_1240|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00849|M.leprae_Br4923 --------------------------------------------------
MAB_1714|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_2731|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3805|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_4469|M.smegmatis_MC2_155 --------------------------------------------------
MAV_3956|M.avium_104 GFSPDDHDRVSAALATVGLDAGLAERRIDQLSGGQMRRVVLAGLLARSPR
TH_0730|M.thermoresistible__bu AALTAATAIIAVVVPFAAGVSLLGTVPMGMLAYRFRFRVLIAATVAGATI
Mb2352c|M.bovis_AF2122/97 --------------------------------------------------
Rv2325c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3625|M.marinum_M --------------------------------------------------
MUL_1240|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00849|M.leprae_Br4923 --------------------------------------------------
MAB_1714|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_2731|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3805|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_4469|M.smegmatis_MC2_155 --------------------------------------------------
MAV_3956|M.avium_104 VLILDEPLAGLDAASQRGLVELLAERRRETGLTVVVISHDFAGLEQLCPR
TH_0730|M.thermoresistible__bu AFLIAGMGGFMTVVNCAYIGGLTGTVKRRGRGTGTVLVAALIAGAAFGAA
Mb2352c|M.bovis_AF2122/97 --------------MTTTS----APARNGTRRPSRPIVLLIPVPGS----
Rv2325c|M.tuberculosis_H37Rv --------------MTTTS----APARNGTRRPSRPIVLLIPVPGS----
MMAR_3625|M.marinum_M --------------MTVSSPSASATPERGSRRAARPVVLLVPVPRG----
MUL_1240|M.ulcerans_Agy99 --------------MTVSSPSASATPERGSRRATRPVVLLVPAPRG----
MLBr_00849|M.leprae_Br4923 --------------MTSLS----MSEHHVPRRRSRPVVLLVPVPGT----
MAB_1714|M.abscessus_ATCC_1997 -----------------------MTKTRAPRR---PVVLLRPVPGT----
Mflv_2731|M.gilvum_PYR-GCK -----------------------MTAAGTPRKPRRQVVLLRPVPGR----
Mvan_3805|M.vanbaalenii_PYR-1 -----------------------MTAAAAPRKPRRQVVVLRPVPGD----
MSMEG_4469|M.smegmatis_MC2_155 -----------------------MSAPGGQRKP---VVLLRPVPGD----
MAV_3956|M.avium_104 ILHLRDGSLDANPVAAQPVPVPVAPPTKRPAARRRPVVLLRPVPGS----
TH_0730|M.thermoresistible__bu IVG-------ALTVLSRLRHLMFDTITANVHGVARIISGIPNMSGAGERL
. : : .
Mb2352c|M.bovis_AF2122/97 ----SVIHDLWAGTKLLVVFGISVLLTFYPGWVTIGMMAALVLAAARIAH
Rv2325c|M.tuberculosis_H37Rv ----SVIHDLWAGTKLLVVFGISVLLTFYPGWVTIGMMAALVLAAARIAH
MMAR_3625|M.marinum_M ----SAIHDLWAGTKLLVVFAISVLLTFYPGWVTIGLMAALVLVAAWIAH
MUL_1240|M.ulcerans_Agy99 ----SAIHDLWAGTKLLVVFAISVLLTFYPGWVTIGLMAALVLVAAWIAH
MLBr_00849|M.leprae_Br4923 ----STIHDLWAGTKLLVVFGVEVLLTFYPGWVTIGLVAALVCGAAWIAR
MAB_1714|M.abscessus_ATCC_1997 ----STIHELWAGTKLIAVFLISVLLTFFPTWTAIGAVAALVILTAWLAH
Mflv_2731|M.gilvum_PYR-GCK ----TPMHDLWAGSKLIIVAAIGVLLTFYPGWVPIAAVALLVVIAARIAR
Mvan_3805|M.vanbaalenii_PYR-1 ----TVIHRLWAGSKLLIVAGIGVLLTFYPGWVPIGAVALLVVVTARMAR
MSMEG_4469|M.smegmatis_MC2_155 ----SVIHQLWAGTKLLSVAVIGIMLTFYPGWVPIGFTAVLVLVVARLAR
MAV_3956|M.avium_104 ----SPIHELWAGTKLLVVFAMSLLLTVFPGWVAIGLATALAAAGLRLAH
TH_0730|M.thermoresistible__bu RRDFETMLSYWP-VLILAAGVISITVVTLIGWWALSRVLARLVVIPDVHK
: *. :: . : : :. * .:. : :
Mb2352c|M.bovis_AF2122/97 IP----RGALPSVPRWLWIVLA---------IGFLTAALAGGTPVVAVGG
Rv2325c|M.tuberculosis_H37Rv IP----RGALPSVPRWLWIVLA---------IGFLTAALAGGTPVVAVGG
MMAR_3625|M.marinum_M IP----RGAVPSMPRWLFVVLA---------FGGLTAALAGGDPMVSVGG
MUL_1240|M.ulcerans_Agy99 IP----RGAVPSMPRWLFVVLA---------FGGLTAALAGGDPMVSVGG
MLBr_00849|M.leprae_Br4923 IP----RDVLPSMPRWLWIVVV---------LGGFTAALAGGSPVVSMGG
MAB_1714|M.abscessus_ATCC_1997 IP----RGAVPTIPIWMVALVI---------GGSLTVFFSGGPPFWHIGG
Mflv_2731|M.gilvum_PYR-GCK IP----RGVLPSIPGWLWFLLL---------LGAVTATFAGGTPEFSVGS
Mvan_3805|M.vanbaalenii_PYR-1 IP----RGVLPTIPAWLWFLLL---------LGAVTAAFAGGDPVIGVGS
MSMEG_4469|M.smegmatis_MC2_155 IP----RGVVPTIPWWMWLLVA---------FGALTATFAGGSPEFDVGS
MAV_3956|M.avium_104 IP----RGVLPSVPRWLWIFLG---------VVGVTAALAGGAPTIHLGT
TH_0730|M.thermoresistible__bu LESFEDTGPVAPVPLRLRDVRFRYPNADRDALGPLTMTVQPGEHVAITGA
: . :..:* : . .* . * *
Mb2352c|M.bovis_AF2122/97 VQLG-------------------LGGALHFLRITALSVVLLALGAMVSWT
Rv2325c|M.tuberculosis_H37Rv VQLG-------------------LGGALHFLRITALSVVLLALGAMVSWT
MMAR_3625|M.marinum_M VELG-------------------LGGALNFLRITALSIVLLALGAMVSWT
MUL_1240|M.ulcerans_Agy99 VELG-------------------LGGALNFLRITALSIVLLALGAMVSWT
MLBr_00849|M.leprae_Br4923 VDIG-------------------LGGVLNFLRITAWSVVLLGLGAMVSWT
MAB_1714|M.abscessus_ATCC_1997 LTIG-------------------FHGVLAVARTTAVAAVLLGTGAMVSWT
Mflv_2731|M.gilvum_PYR-GCK MTVG-------------------LGGLLNFLRITALSIVLLGLGAMVSWT
Mvan_3805|M.vanbaalenii_PYR-1 VEVG-------------------LGGLLNFLRITALATVLLGLGAMVSWT
MSMEG_4469|M.smegmatis_MC2_155 MTIG-------------------LGGLLNFLRITALSIVLLGLGALVSWT
MAV_3956|M.avium_104 ASLG-------------------LGGLLDFLRATALTVVLLGLGALVSWT
TH_0730|M.thermoresistible__bu NGSGKTTLMLLLAGREPTAGTVERPGAVGLGRMGGTAVVMQHPESQVLGT
* * : . * . : *: : * *
Mb2352c|M.bovis_AF2122/97 TNVAEISP-----AVATLGRPFRVLRIP--------------VDEWAVAL
Rv2325c|M.tuberculosis_H37Rv TNVAEISP-----AVATLGRPFRVLRIP--------------VDEWAVAL
MMAR_3625|M.marinum_M TNVAEIGP-----AVATLGRPLRLLRIP--------------VDEWAVVL
MUL_1240|M.ulcerans_Agy99 TNVAEIGP-----AVATLGRPLRLLRIP--------------VDEWAVVL
MLBr_00849|M.leprae_Br4923 TNVAEIGP-----AMATLGRPLRIFRIP--------------VDEWAVAV
MAB_1714|M.abscessus_ATCC_1997 TNVSEIAP-----AVAVLGRPLKVFGIP--------------VDERAATL
Mflv_2731|M.gilvum_PYR-GCK TNVAEVAP-----AVAKLGRPLRPLRIP--------------VDEWAVTI
Mvan_3805|M.vanbaalenii_PYR-1 TNVAEVAP-----AVARLGRPLRPLRIP--------------VDDWAVTL
MSMEG_4469|M.smegmatis_MC2_155 TNVADIAP-----AVATLGRPLGVFRIP--------------VHDWAVTI
MAV_3956|M.avium_104 TNVAQIAP-----AVAALGRPLRVLRIP--------------VDDWSVAL
TH_0730|M.thermoresistible__bu RVADDVVWGLPPGTATDMPRLLEEVGLDGLAERDTGALSGGELQRLAVAA
. :: : : : * : . : :. :..
Mb2352c|M.bovis_AF2122/97 ALALRAFPMLIDEFQVLYAARRLRPKRMPPSRKARR-----QRHARELID
Rv2325c|M.tuberculosis_H37Rv ALALRAFPMLIDEFQVLYAARRLRPKRMPPSRKARR-----QRHARELID
MMAR_3625|M.marinum_M ALALRAFPMLIDEFQVLYAARRLRPRPMPVTRKARR-----QRRGMEVID
MUL_1240|M.ulcerans_Agy99 ALALRAFPMLIDEFQVLYAARRLRPRPMPVTRKARR-----QRRGMEVID
MLBr_00849|M.leprae_Br4923 ALALRAFPMLINEFQVLYAARRLRPKQILNSRKARR-----QRQARELID
MAB_1714|M.abscessus_ATCC_1997 ALALRSFPMLSDEFRVLIAARRLRPPQVREGRRGRRG----LRWIAEAVD
Mflv_2731|M.gilvum_PYR-GCK ALALRAFPMLIDEFSVLYAARRLRPGDVDARRRARV-----RQWASEVID
Mvan_3805|M.vanbaalenii_PYR-1 ALALRAFPMLIDEFSVLYAARRLRPREVDGNRRTKL-----RRWAAEVID
MSMEG_4469|M.smegmatis_MC2_155 ALALRAFPMLIDEFRTLYAARRLRPRERPDTFRARH-----RQRVSGVVD
MAV_3956|M.avium_104 ALALRTFPMLIDEFRVLYAARRLRPRRPAQTRWARL-----RRPATDLID
TH_0730|M.thermoresistible__bu ALAREPSLLIADEITSMVDQQGREALMSVLSGLTHRHRMALVHITHYESE
*** .. :: :*: : : .. : : :
Mb2352c|M.bovis_AF2122/97 LLAAAITVTLRRADE---MGDAITARGGTGQLSAHPGRPKLADWVTLAIT
Rv2325c|M.tuberculosis_H37Rv LLAAAITVTLRRADE---MGDAITARGGTGQLSAHPGRPKLADWVTLAIT
MMAR_3625|M.marinum_M LLAAAITVTLRRADE---MGDAITARGGTGQLSANPTRPKLGDWVTLAIT
MUL_1240|M.ulcerans_Agy99 LLAAAITVTLRRADE---MGDAITARGGTGQLSANPTRPKLGDWVTLAIT
MLBr_00849|M.leprae_Br4923 LLAAAITVTLRRADE---MGDAITARGGIGQLSAYPARPKLADWVTLAIT
MAB_1714|M.abscessus_ATCC_1997 MLTAAITAALRRASE---MGDAITARGGTGQISAHPARPGLNDAIALLLV
Mflv_2731|M.gilvum_PYR-GCK MLAAAVTVALRRADE---MGDAITARGGAGQISAVPSGPKRRDWIAFAVV
Mvan_3805|M.vanbaalenii_PYR-1 LLAAAITVSLRRADE---MGDAITARGGAGQISAAPSGPRRRDWVAFSVV
MSMEG_4469|M.smegmatis_MC2_155 LIAAAVTVALRRGDE---MGDAITARGGTGQFSAAESKPRRLDWVAFAVL
MAV_3956|M.avium_104 VVVAVITVTLRRADE---MGDAITARGGTGQISAAPSRPKRNDWIALSIA
TH_0730|M.thermoresistible__bu AEAADRTIALTGVDDRGTAGGQMVEHVAAPAPSPNPGRPDGAPVLQLTGV
.* * :* .: *. :. : . *. * : :
Mb2352c|M.bovis_AF2122/97 AMASGTAVAIESLILHS---------------------------------
Rv2325c|M.tuberculosis_H37Rv AMASGTAVAIESLILHS---------------------------------
MMAR_3625|M.marinum_M AATSGAAVVIETMLHAA---------------------------------
MUL_1240|M.ulcerans_Agy99 AATSGAAVVIETMLHAA---------------------------------
MLBr_00849|M.leprae_Br4923 ITTSSTAVVLETILHTAS--------------------------------
MAB_1714|M.abscessus_ATCC_1997 IAVGTAVVLFEVL-------------------------------------
Mflv_2731|M.gilvum_PYR-GCK LAVCGVALALELTILGTSGTQR----------------------------
Mvan_3805|M.vanbaalenii_PYR-1 ILVCGAALALELTVLGTSGIRR----------------------------
MSMEG_4469|M.smegmatis_MC2_155 AVVCGTALALELTVLGTSLPRRRG--------------------------
MAV_3956|M.avium_104 SAVCAAAVAAELALLAGH--------------------------------
TH_0730|M.thermoresistible__bu GHEYGSGTPWAATALRDVDLTIHEGEGVLIHGLNGSGKSTLAWIMAGLTV
Mb2352c|M.bovis_AF2122/97 --------------------------------------------------
Rv2325c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3625|M.marinum_M --------------------------------------------------
MUL_1240|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00849|M.leprae_Br4923 --------------------------------------------------
MAB_1714|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_2731|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3805|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_4469|M.smegmatis_MC2_155 --------------------------------------------------
MAV_3956|M.avium_104 --------------------------------------------------
TH_0730|M.thermoresistible__bu PTWGSCLLDGAPVSEQVGAVAISFQAARLQLMRNRVDHEIASAAGFPVRD
Mb2352c|M.bovis_AF2122/97 --------------------------------------------------
Rv2325c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3625|M.marinum_M --------------------------------------------------
MUL_1240|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00849|M.leprae_Br4923 --------------------------------------------------
MAB_1714|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_2731|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3805|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_4469|M.smegmatis_MC2_155 --------------------------------------------------
MAV_3956|M.avium_104 --------------------------------------------------
TH_0730|M.thermoresistible__bu RARVLRALATVGLEPALADRPIDQLSGGQMRRVVLAGLLARSPRALILDE
Mb2352c|M.bovis_AF2122/97 --------------------------------------------------
Rv2325c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3625|M.marinum_M --------------------------------------------------
MUL_1240|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00849|M.leprae_Br4923 --------------------------------------------------
MAB_1714|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_2731|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3805|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_4469|M.smegmatis_MC2_155 --------------------------------------------------
MAV_3956|M.avium_104 --------------------------------------------------
TH_0730|M.thermoresistible__bu PLAGLDAGSQRGLLRILEELRAAGLTLVVISHDFSGLDGLCTRTVHLENG
Mb2352c|M.bovis_AF2122/97 -------------
Rv2325c|M.tuberculosis_H37Rv -------------
MMAR_3625|M.marinum_M -------------
MUL_1240|M.ulcerans_Agy99 -------------
MLBr_00849|M.leprae_Br4923 -------------
MAB_1714|M.abscessus_ATCC_1997 -------------
Mflv_2731|M.gilvum_PYR-GCK -------------
Mvan_3805|M.vanbaalenii_PYR-1 -------------
MSMEG_4469|M.smegmatis_MC2_155 -------------
MAV_3956|M.avium_104 -------------
TH_0730|M.thermoresistible__bu RVVPARTTAGGMS