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EAMDRMDEVDEAIVSLLEDDGRLTHRDIAHRVGLSRSAAAARVQRLIASGQVVVRGVVHPAVLGRGALAH VSVMVDGPAAPIAQILATRDDVAFLSLTSGQFGLIAEARVGSVRDLDGVVATLRSLRGVVGVDTLTYVEV MRDVVGPVGDVSVEVDDTDLALLRALQRDGRASYVELAEAVGLSPAGARRRVVRLIDAQVVRVGAVVRHS GQDRQSAMGLGIRLTGDAGEVLKTLTGMRSVIFVARTLGRFDVLATVRAFSAAQLLEILDAVRGLAGVGV VESWVHLEVVKESYASGLQAG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4457 | - | - | 100% (302) | regulatory protein, AsnC/Lrp |
| M. smegmatis MC2 155 | MSMEG_0838 | - | 2e-32 | 31.29% (294) | AsnC-family protein transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_1663 | - | 3e-19 | 38.78% (147) | transcriptional regulator, AsnC family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2351 | - | 6e-09 | 28.00% (150) | AsnC family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4861 | - | 7e-20 | 37.20% (164) | AsnC family transcriptional regulator |
| M. tuberculosis H37Rv | Rv2324 | - | 6e-09 | 28.00% (150) | AsnC family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3327c | - | 7e-19 | 36.18% (152) | AsnC family transcriptional regulator |
| M. marinum M | MMAR_3557 | - | 5e-20 | 37.09% (151) | Lrp/AsnC family transcriptional regulator |
| M. avium 104 | MAV_2084 | - | 6e-08 | 29.33% (150) | AsnC-family protein transcriptional regulator |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_2790 | - | 3e-09 | 34.23% (111) | Lrp/AsnC family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0159 | - | 1e-122 | 77.29% (295) | AsnC family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_4457|M.smegmatis_MC2_155 MEAMDRMDEVDEAIVSLLEDDGRLTHRDIAHRVGLSRSAAAARVQRLIAS
Mvan_0159|M.vanbaalenii_PYR-1 ------MDELDEAIVELLEVDGRLTHREIARRVGLSRSAAAARVQRLIGS
MMAR_3557|M.marinum_M --------------------------------------------------
MUL_2790|M.ulcerans_Agy99 --------------------------------------------------
Mflv_4861|M.gilvum_PYR-GCK --------------------------------------------------
MAB_3327c|M.abscessus_ATCC_199 --------------------------------------------------
Mb2351|M.bovis_AF2122/97 --------------------------------------------------
Rv2324|M.tuberculosis_H37Rv --------------------------------------------------
MAV_2084|M.avium_104 --------------------------------------------------
MSMEG_4457|M.smegmatis_MC2_155 GQVVVRGVVHPAVLGRGALAHVSVMVDGPAAPIAQILATRDDVAFLSLTS
Mvan_0159|M.vanbaalenii_PYR-1 GQVVIRGAVHPAVLGRGALAHVSVVVHGPAAPVAARLACRDDVPFLSLTS
MMAR_3557|M.marinum_M --------------------------------------------------
MUL_2790|M.ulcerans_Agy99 --------------------------------------------------
Mflv_4861|M.gilvum_PYR-GCK --------------------------------------------------
MAB_3327c|M.abscessus_ATCC_199 --------------------------------------------------
Mb2351|M.bovis_AF2122/97 --------------------------------------------------
Rv2324|M.tuberculosis_H37Rv --------------------------------------------------
MAV_2084|M.avium_104 --------------------------------------------------
MSMEG_4457|M.smegmatis_MC2_155 GQFGLIAEARVGSVRDLDGVVATLRSLRGVVGVDTLTYVEVMRDVVGPVG
Mvan_0159|M.vanbaalenii_PYR-1 GPHGLVAEVRAGSARDIDRAVAELRALPGVSAVDTLTYVEVMRDVIGPVG
MMAR_3557|M.marinum_M ---------------------------MTSSGAPVGNQPEQLRPTG--LG
MUL_2790|M.ulcerans_Agy99 --------------------------------------------------
Mflv_4861|M.gilvum_PYR-GCK ---------------------------MANPGLPHAVGPVSFRVNESRPG
MAB_3327c|M.abscessus_ATCC_199 ---------------------------MAN------KTRRLLRVADPSNG
Mb2351|M.bovis_AF2122/97 --------------------------------------------------
Rv2324|M.tuberculosis_H37Rv --------------------------------------------------
MAV_2084|M.avium_104 --------------------------------------------------
MSMEG_4457|M.smegmatis_MC2_155 DVSVEVDDTDLALLRALQRDGRASYVELAEAVGLSPAGARRRVVRLIDAQ
Mvan_0159|M.vanbaalenii_PYR-1 EVRTEIDDTDRTLLAALQQDGRASYVDLAARVGLSAAGARRRVVRLIDAR
MMAR_3557|M.marinum_M -AATQLDDLSKAIIKELQEDGRRSYSAIAKTVGLSEAAVRQRVQRLIETE
MUL_2790|M.ulcerans_Agy99 ------------------------------------------MQRLIETE
Mflv_4861|M.gilvum_PYR-GCK -AAFQLDELSKAIIEKLQQDGRRSYAGIGKAVGLSEAAVRQRVQRMVDAG
MAB_3327c|M.abscessus_ATCC_199 SAAFPLDEVSKAIVEELQQDGRRPYATIGKSVGLSEAAVRQRVQRMIDAG
Mb2351|M.bovis_AF2122/97 --MDRLDDTDERILAELAEHARATFAEIGHKVSLSAPAVKRRVDRMLESG
Rv2324|M.tuberculosis_H37Rv --MDRLDDTDERILAELAEHARATFAEIGHKVSLSAPAVKRRVDRMLESG
MAV_2084|M.avium_104 --MDRLDDTDERILAELTEQARVTFAEIGDKVNLSAPAVKRRVDRMLDSG
: *::::
MSMEG_4457|M.smegmatis_MC2_155 VVR-VGAVVRHSGQDRQSAMGLGIRLTG--DAGEVLKTLTGMRSVIFVAR
Mvan_0159|M.vanbaalenii_PYR-1 VVR-IGAVVRHSGQDRQSAMGCGIRLTG--DHHDVVAALTDMPAVIFVAR
MMAR_3557|M.marinum_M VMQ-IVAVTDPIQLGFARQALIGIRATG--DTTKLAQQLAAIPAIDYVVL
MUL_2790|M.ulcerans_Agy99 VMQ-IVAVTDPIQLGFARQALIGIRATG--DTTKLAQQLAAIPAIDYVVL
Mflv_4861|M.gilvum_PYR-GCK VMQ-IVAVTDPMQLGFARQAMIGIKCTG--DTTKVAQKLAELPSVDYVVL
MAB_3327c|M.abscessus_ATCC_199 VMQ-IVAVTDPMQLGFKRQAMIGIRCSG--DTTEVADRLSELEAVDYVVL
Mb2351|M.bovis_AF2122/97 VIKGFTTVVDRNALGWNTEAYVQIFCHGRIAPDQLRAAWVNIPEVVSAAT
Rv2324|M.tuberculosis_H37Rv VIKGFTTVVDRNALGWNTEAYVQIFCHGRIAPDQLRAAWVNIPEVVSAAT
MAV_2084|M.avium_104 VIKGFTTVVDRNALGWNTEAYVQVFCHGRIAPDELRTAWVDIPEVFSAAT
*:: . :*. . : * .: : : ..
MSMEG_4457|M.smegmatis_MC2_155 TLGRFDVLATVRAFSAAQLLEILD-AVRGLAGVGVVESWVHLEVVKESYA
Mvan_0159|M.vanbaalenii_PYR-1 TLGRFDVLMTVRAFSAAQLVELMD-TVRALPGVWTLESWTHLDVVKESYA
MMAR_3557|M.marinum_M TAGTFDVIAELVCKDDGDLLDLLNLEIRALPGVLSTETLVYLKLVKQQYN
MUL_2790|M.ulcerans_Agy99 TAGTFDVIAELVCKDDGDLLDLLNLEIRALPGVLSTETLVYLKLVKQQYN
Mflv_4861|M.gilvum_PYR-GCK TAGSFDAIVEVVCEDDDSLLELLNTQIRALPGVIATETLVYLKLVKQQYN
MAB_3327c|M.abscessus_ATCC_199 TAGTFDAIVEVVCEDDDDLLDLLNKQIRAVPGVTSTETLVYLKLVKQQYN
Mb2351|M.bovis_AF2122/97 VTGTSDAILHVLAHDMR-HLEAALERIRSSADVERSESTVVLSNLIDRMP
Rv2324|M.tuberculosis_H37Rv VTGTSDAILHVLAHDMR-HLEAALERIRSSADVERSESTVVLSNLIDRMP
MAV_2084|M.avium_104 VTGTPDAILHVLARDMR-HLEVALERIRSSADVERSESIVVLSNLIDRMR
. * *.: : . . :: :*. ..* *: . *. : :
MSMEG_4457|M.smegmatis_MC2_155 SGLQAG---
Mvan_0159|M.vanbaalenii_PYR-1 SGLDAVTKP
MMAR_3557|M.marinum_M WGVK-----
MUL_2790|M.ulcerans_Agy99 WGVK-----
Mflv_4861|M.gilvum_PYR-GCK WGTR-----
MAB_3327c|M.abscessus_ATCC_199 WGTR-----
Mb2351|M.bovis_AF2122/97 P--------
Rv2324|M.tuberculosis_H37Rv P--------
MAV_2084|M.avium_104 P--------