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PSPPESYGNRPLQSDAVAGDLDSLDLQLIHHLQVDGRIPYAELARRVDVTEKTVRRRVSRLIDENFVTIA AVTDPALLGFGSLALALVTTDGTRSPVDLAAELAQLPETDYITSTTGPYPVVLELVCADARELHDVAFGT IAKTPGVRSVELLPYLRLHYQQAGLSANLVDHGVRPRTLDETDRAILSRLAVDGRAAFRDFAAALGVSET TIRFRYNRLLESNAARVMCIVNPLRLGYRYSSWVTIRVAGRTRAEEVAEALTRLDAVSYVALTAGRWDVL TEVITRTGEDLITVLDNEIRGIDGVASLESWIYITCHYKAVRPRPRRMTGDLDAYGLDPTPVVSQDVS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0838 | - | - | 100% (349) | AsnC-family protein transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_4457 | - | 2e-32 | 31.29% (294) | regulatory protein, AsnC/Lrp |
| M. smegmatis MC2 155 | MSMEG_1663 | - | 5e-22 | 33.82% (136) | transcriptional regulator, AsnC family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3319c | - | 8e-08 | 31.54% (130) | AsnC family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4861 | - | 9e-22 | 39.31% (145) | AsnC family transcriptional regulator |
| M. tuberculosis H37Rv | Rv2324 | - | 1e-07 | 26.32% (114) | AsnC family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3327c | - | 1e-23 | 35.29% (136) | AsnC family transcriptional regulator |
| M. marinum M | MMAR_3557 | - | 1e-23 | 40.72% (167) | Lrp/AsnC family transcriptional regulator |
| M. avium 104 | MAV_3380 | - | 3e-13 | 24.11% (336) | AsnC-family protein transcriptional regulator |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_2790 | - | 2e-14 | 42.86% (105) | Lrp/AsnC family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0159 | - | 5e-37 | 34.01% (294) | AsnC family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3319c|M.bovis_AF2122/97 --------------------------------------------------
Rv2324|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_4861|M.gilvum_PYR-GCK --------------------------------------------------
MAB_3327c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_3557|M.marinum_M --------------------------------------------------
MUL_2790|M.ulcerans_Agy99 --------------------------------------------------
Mvan_0159|M.vanbaalenii_PYR-1 ---------------------MDELDEAIVELLEVDGRLTHREIARRVGL
MSMEG_0838|M.smegmatis_MC2_155 MPSPPESYGNRPLQSDAVAGDLDSLDLQLIHHLQVDGRIPYAELARRVDV
MAV_3380|M.avium_104 ---------------------MEALDGHILHALQLSPRAPFRRIAEVVGA
Mb3319c|M.bovis_AF2122/97 --------------------------------------------------
Rv2324|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_4861|M.gilvum_PYR-GCK --------------------------------------------------
MAB_3327c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_3557|M.marinum_M --------------------------------------------------
MUL_2790|M.ulcerans_Agy99 --------------------------------------------------
Mvan_0159|M.vanbaalenii_PYR-1 SRSAAAARVQRLIGSGQVVIRGAVHPAVLGRGALAHVSVVVHGP--AAPV
MSMEG_0838|M.smegmatis_MC2_155 TEKTVRRRVSRLIDENFVTIAAVTDPALLGFGSLALALVTTDGTRSPVDL
MAV_3380|M.avium_104 GEQTVARRYRALRRDGVLRAVGVVNPRVYG--ECQWIVRVRAKPDDLLRL
Mb3319c|M.bovis_AF2122/97 --------------------------------------------------
Rv2324|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_4861|M.gilvum_PYR-GCK --------------------------------------------------
MAB_3327c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_3557|M.marinum_M --------------------------------------------------
MUL_2790|M.ulcerans_Agy99 --------------------------------------------------
Mvan_0159|M.vanbaalenii_PYR-1 AARLACRDDVPFLSLTSGPHGLVAEVRA----------------GSARDI
MSMEG_0838|M.smegmatis_MC2_155 AAELAQLPETDYITSTTGPYPVVLELVC----------------ADAREL
MAV_3380|M.avium_104 AEALVRRADVTHANVLSGGTELVCVVRAPLDDTEAGLLHRLPRTSTVLDM
Mb3319c|M.bovis_AF2122/97 -----------------------------------------MNEALDDID
Rv2324|M.tuberculosis_H37Rv ------------------------------------------MDRLDDTD
Mflv_4861|M.gilvum_PYR-GCK -----------------MANPGLPHAVGPVSFRVNESRPG-AAFQLDELS
MAB_3327c|M.abscessus_ATCC_199 -----------------MAN------KTRRLLRVADPSNGSAAFPLDEVS
MMAR_3557|M.marinum_M -----------------MTSSGAP--VGNQPEQLRPTGLG-AATQLDDLS
MUL_2790|M.ulcerans_Agy99 --------------------------------------------------
Mvan_0159|M.vanbaalenii_PYR-1 DRAVA-------ELRALPGVSAVDTLTYVEVMRDVIGPVGEVRTEIDDTD
MSMEG_0838|M.smegmatis_MC2_155 HDVAFGTIAKTPGVRSVELLPYLRLHYQQAGLSANLVDHGVRPRTLDETD
MAV_3380|M.avium_104 RVDLVINVFGAPMHAHWTGHGHALDGHQVAALRPAHCAHPDRPVGPTPED
Mb3319c|M.bovis_AF2122/97 RILVRELAADGRVTLSELATRAGLSVSAVQSRVRRLESRGVVQGYSARIN
Rv2324|M.tuberculosis_H37Rv ERILAELAEHARATFAEIGHKVSLSAPAVKRRVDRMLESGVIKGFTTVVD
Mflv_4861|M.gilvum_PYR-GCK KAIIEKLQQDGRRSYAGIGKAVGLSEAAVRQRVQRMVDAGVMQ-IVAVTD
MAB_3327c|M.abscessus_ATCC_199 KAIVEELQQDGRRPYATIGKSVGLSEAAVRQRVQRMIDAGVMQ-IVAVTD
MMAR_3557|M.marinum_M KAIIKELQEDGRRSYSAIAKTVGLSEAAVRQRVQRLIETEVMQ-IVAVTD
MUL_2790|M.ulcerans_Agy99 --------------------------------MQRLIETEVMQ-IVAVTD
Mvan_0159|M.vanbaalenii_PYR-1 RTLLAALQQDGRASYVDLAARVGLSAAGARRRVVRLIDARVVR-IGAVVR
MSMEG_0838|M.smegmatis_MC2_155 RAILSRLAVDGRAAFRDFAAALGVSETTIRFRYNRLLESNAAR-VMCIVN
MAV_3380|M.avium_104 QPLLDALAEDGRISDSALAGLTGWSPARVKRRMVALQGSGTLS-FDLDVL
: .
Mb3319c|M.bovis_AF2122/97 PEAVGHLLSAFVAITPLDPSQPDDAPARLEHIEEVESCYSVAGEESYVLL
Rv2324|M.tuberculosis_H37Rv RNALGWNTEAYVQIFCHGRIAPDQLRAAWVNIPEVVSAATVTGTSDAILH
Mflv_4861|M.gilvum_PYR-GCK PMQLGFARQAMIGIKCTG--DTTKVAQKLAELPSVDYVVLTAGSFDAIVE
MAB_3327c|M.abscessus_ATCC_199 PMQLGFKRQAMIGIRCSG--DTTEVADRLSELEAVDYVVLTAGTFDAIVE
MMAR_3557|M.marinum_M PIQLGFARQALIGIRATG--DTTKLAQQLAAIPAIDYVVLTAGTFDVIAE
MUL_2790|M.ulcerans_Agy99 PIQLGFARQALIGIRATG--DTTKLAQQLAAIPAIDYVVLTAGTFDVIAE
Mvan_0159|M.vanbaalenii_PYR-1 HSGQDRQSAMGCGIRLTG--DHHDVVAALTDMPAVIFVARTLGRFDVLMT
MSMEG_0838|M.smegmatis_MC2_155 PLRLGYRYSSWVTIRVAGRTRAEEVAEALTRLDAVSYVALTAGRWDVLTE
MAV_3380|M.avium_104 PERLGFMLHAIIWISVVP-QHLTSVAEQIVRHDEVASVATVSGPANLMVV
. * . : . * . :
Mb3319c|M.bovis_AF2122/97 VRVASARALEDLLQR-IRTTANVRTRSTIILNTFYSDRQHIP--------
Rv2324|M.tuberculosis_H37Rv VLAHDMRHLEAALER-IRSSADVERSESTVVLSNLIDRMPP---------
Mflv_4861|M.gilvum_PYR-GCK VVCEDDDSLLELLNTQIRALPGVIATETLVYLKLVKQQYNWGTR------
MAB_3327c|M.abscessus_ATCC_199 VVCEDDDDLLDLLNKQIRAVPGVTSTETLVYLKLVKQQYNWGTR------
MMAR_3557|M.marinum_M LVCKDDGDLLDLLNLEIRALPGVLSTETLVYLKLVKQQYNWGVK------
MUL_2790|M.ulcerans_Agy99 LVCKDDGDLLDLLNLEIRALPGVLSTETLVYLKLVKQQYNWGVK------
Mvan_0159|M.vanbaalenii_PYR-1 VRAFSAAQLVELMDT-VRALPGVWTLESWTHLDVVKESYASGLDAVTKP-
MSMEG_0838|M.smegmatis_MC2_155 VITRTGEDLITVLDNEIRGIDGVASLESWIYITCHYKAVRPRPRRMTGDL
MAV_3380|M.avium_104 VICRDPEHFYRYLAERLASVDHIQAYDVSVRSKRLKQVGSLIAHGRLVRA
: : : : : . .
Mb3319c|M.bovis_AF2122/97 ----------------
Rv2324|M.tuberculosis_H37Rv ----------------
Mflv_4861|M.gilvum_PYR-GCK ----------------
MAB_3327c|M.abscessus_ATCC_199 ----------------
MMAR_3557|M.marinum_M ----------------
MUL_2790|M.ulcerans_Agy99 ----------------
Mvan_0159|M.vanbaalenii_PYR-1 ----------------
MSMEG_0838|M.smegmatis_MC2_155 DAYGLDPTPVVSQDVS
MAV_3380|M.avium_104 AR--------------