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LDVGTPAPDFTLRDQNNRPVTLSDYRTGENPRDVLVVFFPLAFTGVCEGELGAIRDQLPLYENDHSAVIA VSVGPPPTHKIWSIESGFTFPVLSDFWPHGKVARDYGVFNEDAGYPNRGTFVVDRSGIIRFAEMMEPGQV RDQKVWTAALQALRA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4320 | - | - | 100% (156) | alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen |
| M. smegmatis MC2 155 | MSMEG_4753 | - | 7e-12 | 33.81% (139) | antioxidant, AhpC/TSA family protein |
| M. smegmatis MC2 155 | MSMEG_4891 | - | 2e-05 | 26.95% (141) | alkylhydroperoxide reductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2262c | ahpE | 5e-62 | 69.87% (156) | peroxiredoxin AhpE |
| M. gilvum PYR-GCK | Mflv_2784 | - | 4e-54 | 60.00% (155) | alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal |
| M. tuberculosis H37Rv | Rv2238c | ahpE | 5e-62 | 69.87% (156) | peroxiredoxin AhpE |
| M. leprae Br4923 | MLBr_00424 | bcp | 1e-09 | 32.61% (138) | putative antioxidant protein |
| M. abscessus ATCC 19977 | MAB_1887 | - | 1e-56 | 66.03% (156) | peroxiredoxin (thioredoxin reductase) AhpE |
| M. marinum M | MMAR_3331 | ahpE | 6e-64 | 70.51% (156) | peroxiredoxin AhpE |
| M. avium 104 | MAV_2199 | - | 1e-65 | 71.79% (156) | alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal |
| M. thermoresistible (build 8) | TH_1342 | ahpE | 3e-64 | 71.61% (155) | Probable peroxiredoxin AhpE |
| M. ulcerans Agy99 | MUL_1311 | ahpE | 4e-64 | 70.51% (156) | peroxiredoxin AhpE |
| M. vanbaalenii PYR-1 | Mvan_3749 | - | 8e-58 | 64.10% (156) | redoxin domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2262c|M.bovis_AF2122/97 -----MLNVGATAPDFTLRDQNQQLVTLRGYR-GA--KNVLLVFFPLAFT
Rv2238c|M.tuberculosis_H37Rv -----MLNVGATAPDFTLRDQNQQLVTLRGYR-GA--KNVLLVFFPLAFT
MMAR_3331|M.marinum_M -----MLEVGATAPDFTLRDQNQQPVTLSDYR-GA--KNVLLVFFPLAFT
MUL_1311|M.ulcerans_Agy99 -----MLEVGATAPDFTLRDQNQQPVTLSDYR-GA--KNVLLVFFPLAFT
MAV_2199|M.avium_104 -----MLSVGTPAPDFTLRDQNQQRVTLSSFR-GS--KNVLLVFFPLAFT
TH_1342|M.thermoresistible__bu -----LLEVGVEAPDFTLKDQNGRSFTLSDLR-GE--KNVLIVFFPLAFT
Mflv_2784|M.gilvum_PYR-GCK -----MLSVGSPAPDFTLKDQNNQVVSLAAFR-GD--RDVVLVFFPLAFT
Mvan_3749|M.vanbaalenii_PYR-1 -----MLSVGEPAPDFTLKDQNNQPVTLSGFR-GA--KNVLLVFFPLAFT
MSMEG_4320|M.smegmatis_MC2_155 -----MLDVGTPAPDFTLRDQNNRPVTLSDYRTGENPRDVLVVFFPLAFT
MAB_1887|M.abscessus_ATCC_1997 -----MLPVGTVAPDFTLRNQNNQPVSLSDFR-GK--KAVLLVFFPLAFT
MLBr_00424|M.leprae_Br4923 MTETTRLAPGDQAPAFSLPDADGRIVSLGDYR-GQ---RVTVYFYPAALT
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Mb2262c|M.bovis_AF2122/97 GICQGELDQLRDHLPEFENDDSAALAISVGPPPTHKIWATQSGFTFPLLS
Rv2238c|M.tuberculosis_H37Rv GICQGELDQLRDHLPEFENDDSAALAISVGPPPTHKIWATQSGFTFPLLS
MMAR_3331|M.marinum_M GICQGELDQIRDHLPQFENDDTAAVAISVGPPPTHKIWATQSGFTFPVLS
MUL_1311|M.ulcerans_Agy99 GICQGELDQIRDHLPQFENDDTAAVAISVGPPPTHKIWATQSGFTFPVLS
MAV_2199|M.avium_104 GICQGELDQLRDHLPEFENDDSAVLAISVGPPPTHRIWALESGFTFPVLS
TH_1342|M.thermoresistible__bu GICQGELDEIRDHLPEYENDDTQTVAISVGPPPTHKIWAIQSGFTFPVLS
Mflv_2784|M.gilvum_PYR-GCK GICQRELDEIRHHIGDFVNDETATLTISVGPSPVHKVWATQRGYSFPVLS
Mvan_3749|M.vanbaalenii_PYR-1 GICQRELDEIRDRLGDFVNEETATLAISVGPSPTHKVWATERGYTFPVLS
MSMEG_4320|M.smegmatis_MC2_155 GVCEGELGAIRDQLPLYENDHSAVIAVSVGPPPTHKIWSIESGFTFPVLS
MAB_1887|M.abscessus_ATCC_1997 GVCQGELDHVRDHIGDFENDEVQIIALSVSAGPIHKIWSSYSGFTFPILS
MLBr_00424|M.leprae_Br4923 PGCTKQACDFRDNLHDLNDAGLDVVGISPDPLTKLAEFRDAEALTFPLLS
* : .*..: : : :* .. . : . :**:**
Mb2262c|M.bovis_AF2122/97 DFWPHGAVSQ-AYG---VFNEQAGIANRGTFVVDRSGIIRFAEMKQPGEV
Rv2238c|M.tuberculosis_H37Rv DFWPHGAVSQ-AYG---VFNEQAGIANRGTFVVDRSGIIRFAEMKQPGEV
MMAR_3331|M.marinum_M DFWPHGAVSQ-AYG---VFNDTAGISNRGTFVVDRAGIIRFAEMKQPGEA
MUL_1311|M.ulcerans_Agy99 DFWPHGAVSQ-AYG---VFNDTAGISNRGTFVVDRAGIIRFAEMKQPGEA
MAV_2199|M.avium_104 DFWPHGAVSQ-SYG---VFNDEAGYSNRGTFVVDRSGIIRFAEMKQPGES
TH_1342|M.thermoresistible__bu DFWPHGAVAQ-AYG---VFNETAGFPNRGTFVVDRAGIIRFAEMKDPGEP
Mflv_2784|M.gilvum_PYR-GCK DFWPHGAVSQ-AYG---VFNDATGFSNRGTFVVDRSGLVRFAECKEPGEA
Mvan_3749|M.vanbaalenii_PYR-1 DFWPHGEIAR-AYG---VFNDASGFANRGTFVVDRSGIVAFAECKQPGEA
MSMEG_4320|M.smegmatis_MC2_155 DFWPHGKVAR-DYG---VFNEDAGYPNRGTFVVDRSGIIRFAEMMEPGQV
MAB_1887|M.abscessus_ATCC_1997 DFWPHGAVAE-AYG---VLNEKAGYPNRGTFVVDADGIIRFAEMLDPGQA
MLBr_00424|M.leprae_Br4923 DHDCKVLSAWGAYGKKQIYGKTVLGVIRSTFVVDEKGKIVLAQYNVKATG
*. : : ** : .. *.***** * : :*: .
Mb2262c|M.bovis_AF2122/97 RDQRLWTDALAALTA-
Rv2238c|M.tuberculosis_H37Rv RDQRLWTDALAALTA-
MMAR_3331|M.marinum_M RDQRLWTDALAALQA-
MUL_1311|M.ulcerans_Agy99 RDQRLWTDALAALQA-
MAV_2199|M.avium_104 RDQRLWTDALAALKA-
TH_1342|M.thermoresistible__bu RDRKVWSEALEALRKS
Mflv_2784|M.gilvum_PYR-GCK RDQAAWTRALAALRG-
Mvan_3749|M.vanbaalenii_PYR-1 RDQAVWGQALNTLRSG
MSMEG_4320|M.smegmatis_MC2_155 RDQKVWTAALQALRA-
MAB_1887|M.abscessus_ATCC_1997 RDQAGWVQALAALHS-
MLBr_00424|M.leprae_Br4923 -HVAKLRRDLSLLECC
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