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RTDPLKTFHDMELGARAEHTAVVSAETIRTYARLSGDHNPIHEDAAYAATTRFGRPVAHGMLVAGYVQTA LTKLVAPGGVSTGYQFDLLAPVFEDTAITAQAVCTHLDPVTNRATFTITVVDDTTRKQLISGSAVVAFPK GEK*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4173 | - | - | 100% (144) | MaoC family protein |
| M. smegmatis MC2 155 | MSMEG_6754 | - | 1e-06 | 29.58% (142) | MaoC like domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_4757 | - | 2e-05 | 36.84% (57) | fatty acid synthase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0655 | - | 1e-07 | 28.78% (139) | (3R)-hydroxyacyl-ACP dehydratase subunit HadB |
| M. gilvum PYR-GCK | Mflv_4895 | - | 5e-06 | 34.78% (69) | dehydratase |
| M. tuberculosis H37Rv | Rv0636 | - | 1e-07 | 28.78% (139) | (3R)-hydroxyacyl-ACP dehydratase subunit HadB |
| M. leprae Br4923 | MLBr_01909 | - | 9e-07 | 28.80% (125) | (3R)-hydroxyacyl-ACP dehydratase subunit HadB |
| M. abscessus ATCC 19977 | MAB_0621c | - | 8e-07 | 41.27% (63) | MaoC family dehydrogenase/dehydratase |
| M. marinum M | MMAR_0969 | - | 3e-07 | 28.78% (139) | hypothetical protein MMAR_0969 |
| M. avium 104 | MAV_5174 | - | 1e-06 | 24.83% (149) | ZbpA protein |
| M. thermoresistible (build 8) | TH_0555 | - | 3e-07 | 32.80% (125) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_0721 | - | 2e-07 | 28.78% (139) | (3R)-hydroxyacyl-ACP dehydratase subunit HadB |
| M. vanbaalenii PYR-1 | Mvan_3988 | - | 2e-06 | 31.62% (117) | dehydratase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4895|M.gilvum_PYR-GCK MPIDPG-ALGASTPPAIFRWTDRDTLLYALGVGAGTDDLAFTTEN-SHDV
MAB_0621c|M.abscessus_ATCC_199 MPINVDIALGAATEPAEFSWTASDVQLYHLAIGAGADPVSETELRYLQDK
MMAR_0969|M.marinum_M --------------------------------------------------
MUL_0721|M.ulcerans_Agy99 --------------------------------------------------
Mb0655|M.bovis_AF2122/97 --------------------------------------------------
Rv0636|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01909|M.leprae_Br4923 --------------------------------------------------
MAV_5174|M.avium_104 --------------------------------------------------
TH_0555|M.thermoresistible__bu --------------------------------------------------
Mvan_3988|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_4173|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_4895|M.gilvum_PYR-GCK TQQVLPTYAVIACSPFAAITKIGSF-----DFSRLLHGSQRIRVFSPLPA
MAB_0621c|M.abscessus_ATCC_199 TPQVLPTFATVASGFHAVEPPKVSFPGIEIDLAKILHGTEQVTAHRPLPP
MMAR_0969|M.marinum_M --------------------------------------------------
MUL_0721|M.ulcerans_Agy99 --------------------------------------------------
Mb0655|M.bovis_AF2122/97 --------------------------------------------------
Rv0636|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01909|M.leprae_Br4923 --------------------------------------------------
MAV_5174|M.avium_104 --------------------------------------------------
TH_0555|M.thermoresistible__bu --------------------------------------------------
Mvan_3988|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_4173|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_4895|M.gilvum_PYR-GCK AGALSVVSEVADIQDKGEGKNAVVMLKGTGRDPDTGAVVAETLTTLVLRG
MAB_0621c|M.abscessus_ATCC_199 SGTARSEGKVVEIWDKG--KAAVIVTETTTSD-DQGPLWTIRR-SIFARG
MMAR_0969|M.marinum_M ------------------------MALREFSSVNVGDQLPERTYPLTRQD
MUL_0721|M.ulcerans_Agy99 ------------------------MALREFSSVNVGDQLPERTYPLTRQD
Mb0655|M.bovis_AF2122/97 ------------------------MALREFSSVKVGDQLPEKTYPLTRQD
Rv0636|M.tuberculosis_H37Rv ------------------------MALREFSSVKVGDQLPEKTYPLTRQD
MLBr_01909|M.leprae_Br4923 ------------------------MARREFSSVKVGDLLPEKTYPLTRQD
MAV_5174|M.avium_104 -------MRT--------------FESVADLAAAAGETLGHSDWVTITQE
TH_0555|M.thermoresistible__bu -----MTSRTGTAQPGQSAPAPTVYQGLSEFEAQLGRHLGYSDWHRVTQE
Mvan_3988|M.vanbaalenii_PYR-1 --------------------------MIGIDSVAVGDELPPLQAPDVSRL
MSMEG_4173|M.smegmatis_MC2_155 ---------------------MRTDPLKTFHDMELGAR--AEHTAVVSAE
*
Mflv_4895|M.gilvum_PYR-GCK EGGFGGQPGSRPTAPPVPDREPDARVSLPTREDQALIYRLSGDRNPLHSD
MAB_0621c|M.abscessus_ATCC_199 EGGFGGERGPSSHGG-VPERDADLEVSTHILPQQALLYRLCGDRNPLHSD
MMAR_0969|M.marinum_M LVNYAG---------------------------------VSGDLNPIHWD
MUL_0721|M.ulcerans_Agy99 LVNYAG---------------------------------VSGDLNPIHWD
Mb0655|M.bovis_AF2122/97 LVNYAG---------------------------------VSGDLNPIHWD
Rv0636|M.tuberculosis_H37Rv LVNYAG---------------------------------VSGDLNPIHWD
MLBr_01909|M.leprae_Br4923 LVNYAG---------------------------------VSGDLNPIHWD
MAV_5174|M.avium_104 DVNLFAD--------------------------------ATGDHQWIHVD
TH_0555|M.thermoresistible__bu QIDLFAE--------------------------------ATGDRQWIHVD
Mvan_3988|M.vanbaalenii_PYR-1 TLALFAG--------------------------------ASGDHNPMHVD
MSMEG_4173|M.smegmatis_MC2_155 TIRTYAR--------------------------------LSGDHNPIHED
. ** : :* *
Mflv_4895|M.gilvum_PYR-GCK PWFAQLAGFRRPILHGLCTYGVAGRALVSELGGGDATRITAI---AARFV
MAB_0621c|M.abscessus_ATCC_199 PAFAAAAGFPRPILHGLCSYGVVCKAAVDAALDGDVSRVTSY---AAKFA
MMAR_0969|M.marinum_M DEIAKLVGLDTAIAHGMLTMGIGGGYVTSWV--GDPGAVTEY---NVRFT
MUL_0721|M.ulcerans_Agy99 DEIAKLVGLDTAIAHGMLTMGIGGGYVTSWV--GDPGAVTEY---NVRFT
Mb0655|M.bovis_AF2122/97 DEIAKVVGLDAAIAHGMLTMGIGGGYVTSWV--GDPGAVTEY---NVRFT
Rv0636|M.tuberculosis_H37Rv DEIAKVVGLDTAIAHGMLTMGIGGGYVTSWV--GDPGAVTEY---NVRFT
MLBr_01909|M.leprae_Br4923 DEIAKVVGLDTAIAHGMLTMGIGGGYVTSWV--GDPGAVIEY---NVRFT
MAV_5174|M.avium_104 PERAASGPFGTTIAHGFMTLALLPRLQHQIYTVNGIKLAINYGLNKVRFP
TH_0555|M.thermoresistible__bu AEKAATGPYGKTIAHGYLTLSLVPLLIKQIYRVEGLSMQVNYGVDKLRFP
Mvan_3988|M.vanbaalenii_PYR-1 LDEARSAGLPDVFAHGMLSMAYLGRLITDWVP---QERLRTF---RVRFA
MSMEG_4173|M.smegmatis_MC2_155 AAYAATTRFGRPVAHGMLVAGYVQTALTKLVAPGGVSTGYQF-----DLL
* . ** . . :
Mflv_4895|M.gilvum_PYR-GCK APVLP-----GDTLTTSIWRVESGRGVFRTEAANADGSDSRSVLEDGEVE
MAB_0621c|M.abscessus_ATCC_199 GVVFP-----GETLKTRIWKED---GKLLISAVVADREDAPALAD---VE
MMAR_0969|M.marinum_M AVVPVPNDGKGAELVFNGRVKSVDPDSKSVTIALTATTGGKKIFGRAIAS
MUL_0721|M.ulcerans_Agy99 AVVPVPNDGKGAELVFNGRVKSVDPDSKSVTIALTATTGGKKIFGRAIAS
Mb0655|M.bovis_AF2122/97 AVVPVPNDGKGAELVFNGRVKSVDPESKSVTIALTATTGGKKIFGRAIAS
Rv0636|M.tuberculosis_H37Rv AVVPVPNDGKGAELVFNGRVKSVDPESKSVTIALTATTGGKKIFGRAIAS
MLBr_01909|M.leprae_Br4923 AVVPVPNDGQGAVLVFSGKVKSVDPDTKSVTIALSATTGGKKIFGRAIAS
MAV_5174|M.avium_104 APVPVGSRVRAQSSLVGVDDLGNGAVQATVSTTVEIDGSAKPACVAESIV
TH_0555|M.thermoresistible__bu APVPVDSRIRAGAELVGVERSGNGAR-ATVRVTVEVDGGDRPACVVDTIA
Mvan_3988|M.vanbaalenii_PYR-1 AITPVHARPTCTGRVTDISVVD-GERRATVEIVVTLADGTITLSGDAVVG
MSMEG_4173|M.smegmatis_MC2_155 APVFEDTAITAQAVCTHLDPVTN--RATFTITVVDDTTRKQLISGSAVVA
. . .
Mflv_4895|M.gilvum_PYR-GCK FVDNQR
MAB_0621c|M.abscessus_ATCC_199 LTHS--
MMAR_0969|M.marinum_M AKLA--
MUL_0721|M.ulcerans_Agy99 AKLA--
Mb0655|M.bovis_AF2122/97 AKLA--
Rv0636|M.tuberculosis_H37Rv AKLA--
MLBr_01909|M.leprae_Br4923 AKLA--
MAV_5174|M.avium_104 RYIS--
TH_0555|M.thermoresistible__bu LMVP--
Mvan_3988|M.vanbaalenii_PYR-1 L-----
MSMEG_4173|M.smegmatis_MC2_155 FPKGEK