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MDKVKVAIIGSGNIGTDLMMKTLRSSSLEMAVLVGVDPRSDGLARAERLGIATTSGGLDHFVTTPEFEDV AIVFDATSAAAHERHASILAQLNKQVVDLTPAAVGPYVIPTVNMDRVVGEPNVNMVTCGGQATVPIVAAI SGVTPVHYAEIVASIASRSAGPGTRANIDEFTETTALALESVGGATQGKAIIVLNPAEPPLIMRDTVLCL CDEADETEIEAAVERMVASVAEFVPGYRLKQKVQFQRYTRNSPLRLPEQEADFTGLQVSVFLEVEGAAHY LPAYAGNLDIMTSAALRTAERMTELDAIRGK
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4149 | - | - | 100% (311) | acetaldehyde dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_5939 | - | 1e-79 | 51.63% (306) | acetaldehyde dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3565c | - | 3e-83 | 52.75% (309) | acetaldehyde dehydrogenase |
| M. gilvum PYR-GCK | Mflv_1521 | - | 1e-80 | 51.99% (302) | acetaldehyde dehydrogenase |
| M. tuberculosis H37Rv | Rv3535c | - | 3e-83 | 52.75% (309) | acetaldehyde dehydrogenase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4374 | - | 1e-102 | 64.12% (301) | acetaldehyde dehydrogenase |
| M. marinum M | MMAR_5022 | mhpF_1 | 7e-80 | 52.13% (305) | acetaldehyde dehydrogenase, MhpF_1 |
| M. avium 104 | MAV_0626 | - | 4e-82 | 53.14% (303) | acetaldehyde dehydrogenase |
| M. thermoresistible (build 8) | TH_0370 | - | 3e-78 | 51.31% (306) | PROBABLE ACETALDEHYDE DEHYDROGENASE (ACETALDEHYDE DEHYDROGENASE |
| M. ulcerans Agy99 | MUL_4096 | mhpF_1 | 2e-80 | 52.12% (307) | acetaldehyde dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_4392 | - | 1e-102 | 63.04% (303) | acetaldehyde dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3565c|M.bovis_AF2122/97 ----MPSKAKVAIVGSGNISTDLLYKLLRSE-WLEPRWMVGIDPESDGLA
Rv3535c|M.tuberculosis_H37Rv ----MPSKAKVAIVGSGNISTDLLYKLLRSE-WLEPRWMVGIDPESDGLA
MAV_0626|M.avium_104 ----MPTKAKVAIVGSGNISTDLLYKLLRSD-WLEPRWMVGIDPQSEGLA
MMAR_5022|M.marinum_M ----MPSKASVAIVGSGNISTDLLYKLLRSD-WLEPRWMVGIDPQSEGLA
MUL_4096|M.ulcerans_Agy99 ----MPSKASVAIVGSGNISTDLLYKLLRSD-WLEPRWMVGIDPQSEGLA
Mflv_1521|M.gilvum_PYR-GCK ----MADKLSVAIVGSGNISTDLLYKLLRSE-WLEPRWMIGIDPESEGLA
TH_0370|M.thermoresistible__bu MTATTGRKLQAAIVGSGNISTDLLYKLLRSD-WLEPRWMIGIDPASEGLA
MSMEG_4149|M.smegmatis_MC2_155 -----MDKVKVAIIGSGNIGTDLMMKTLRSS-SLEMAVLVGVDPRSDGLA
MAB_4374|M.abscessus_ATCC_1997 ----------MAIIGSGNIGTDLMIKVIRRSRILSMGAMVGIDPTSDGLA
Mvan_4392|M.vanbaalenii_PYR-1 -------MRKVAIIGSGNIGTDLMIKVLRVSDLLEVAAMVGIDPDSDGLA
**:*****.***: * :* . *. ::*:** *:***
Mb3565c|M.bovis_AF2122/97 RAAKLGLETTHEGVDWLLAQPD--KPDLVFEATSAYVHRDAAPKYAEAGI
Rv3535c|M.tuberculosis_H37Rv RAAKLGLETTHEGVDWLLAQPD--KPDLVFEATSAYVHRDAAPKYAEAGI
MAV_0626|M.avium_104 RARKLGLETTHEGVDWLLAQPE--KPDLVFEATSAYVHRDAAPKYEAAGI
MMAR_5022|M.marinum_M RARKLGLETTHEGVDWLLAQSD--KPDLVFEATSAYVHKAAAPKYAAAGI
MUL_4096|M.ulcerans_Agy99 RARKLGLETTHEGVDWLVAQSD--KPDLVFEATSAYVHKAAAPKYAAAGI
Mflv_1521|M.gilvum_PYR-GCK RARKLGLETSHEGVDWLLARDE--KPDMVFEATSAYVHRDAAPRYAEAGI
TH_0370|M.thermoresistible__bu RARKLGLETSHEGVDWLFAQDE--KPDIVFEATSAYVHREAAPRYAEAGI
MSMEG_4149|M.smegmatis_MC2_155 RAERLGIATTSGGLDHFVTTPEFEDVAIVFDATSAAAHERHASILAQLNK
MAB_4374|M.abscessus_ATCC_1997 RAARLGVATTADGVEGLIHMEQFAEVAIIFDATSAATHRENAARLAPYDK
Mvan_4392|M.vanbaalenii_PYR-1 RARRLKVQTTHEGVEGLLALDEFDEIDIVFDATSAGAHIKNAETLRKFGK
** :* : *: *:: :. : . ::*:**** .* * .
Mb3565c|M.bovis_AF2122/97 RAIDLTPAAVGPAVIPPANLREH--LDAPNVNMITCGGQATIPIVYAVSR
Rv3535c|M.tuberculosis_H37Rv RAIDLTPAAVGPAVIPPANLREH--LDAPNVNMITCGGQATIPIVYAVSR
MAV_0626|M.avium_104 RAIDLTPAAVGPAVIPPANLRQH--LDAPNVNMITCGGQATIPIVYAVSR
MMAR_5022|M.marinum_M RAIDLTPAAVGPAVVPPANLREH--LDAPNVNMITCGGQATIPIVYAVSR
MUL_4096|M.ulcerans_Agy99 RAIDLTPAAVGPAVVPPANLREH--LDAPNVNMITCGGQATIPIVYAVSR
Mflv_1521|M.gilvum_PYR-GCK RAIDLTPAAIGPGVIPPANLREH--LDAPNVNMVTCGGQATIPMVHAVSR
TH_0370|M.thermoresistible__bu RAIDLTPAAVGPGVIPPANLREH--LDAPNVNMVTCGGQATIPIVHAVVR
MSMEG_4149|M.smegmatis_MC2_155 QVVDLTPAAVGPYVIPTVNMDR--VVGEPNVNMVTCGGQATVPIVAAISG
MAB_4374|M.abscessus_ATCC_1997 RLIDLTPAAVGPYVVPPVNLGAHIASGATNLNMVTCGGQATIPIVHAVSR
Mvan_4392|M.vanbaalenii_PYR-1 YLVDLTPAAIGPFVVPAVNLTDQLNRNVDNVNMVTCGGQATIPIVAAVSQ
:******:** *:*..*: . *:**:*******:*:* *:
Mb3565c|M.bovis_AF2122/97 IVE-----VPYAEIVASVASVSAGPGTRANIDEFTKTTARGVQTIGGAAR
Rv3535c|M.tuberculosis_H37Rv IVE-----VPYAEIVASVASVSAGPGTRANIDEFTKTTARGVQTIGGAAR
MAV_0626|M.avium_104 VVE-----VPYAEIVASVASVSAGPGTRANIDEFTKTTSRGVETIGGAKR
MMAR_5022|M.marinum_M AVADLGG-VPYAEIVASVASVSAGPGTRANIDEFTKTTSKGVETIGGARR
MUL_4096|M.ulcerans_Agy99 AVADLGG-VPYAEIVASVASVSAGPGTRANIDEFTKTTSKGVETIGGARR
Mflv_1521|M.gilvum_PYR-GCK VVD-----VPYAEIVASVSSASAGPGTRANIDEFTKTTSAGVEVIGGARR
TH_0370|M.thermoresistible__bu AVAAHGGTVPYAEIVASVASVSAGPGTRANIDEFTKTTSKGVETIGGAQR
MSMEG_4149|M.smegmatis_MC2_155 VTP-----VHYAEIVASIASRSAGPGTRANIDEFTETTALALESVGGATQ
MAB_4374|M.abscessus_ATCC_1997 VAP-----VVYAEIVASISSRSAGPGTRANIDEFTETTARAIEQVGGAAR
Mvan_4392|M.vanbaalenii_PYR-1 VTP-----VAYAEIVASISSKSAGPGTRANIDEFTETTAQAIESVGGAAR
. * *******::* **************:**: .:: :*** :
Mb3565c|M.bovis_AF2122/97 GKAIIILNPADPPMIMRDTIFCAIPTDADREAIAASIHDVVKEVQTYVPG
Rv3535c|M.tuberculosis_H37Rv GKAIIILNPADPPMIMRDTIFCAIPTDADREAIAASIHDVVKEVQTYVPG
MAV_0626|M.avium_104 GKAIIILNPADPPMIMRDTIFCAIPEDADRDAIAQSIHDVVKEVQSYVPG
MMAR_5022|M.marinum_M GKAIIILNPADPPMIMRDTIFCAIPEDADRDAIAASIHEVVAQVQTYVPG
MUL_4096|M.ulcerans_Agy99 GKAIIILNPADPPMIMRDTIFCAIPEDADRDAIAASIHEVVAQVQTYVPG
Mflv_1521|M.gilvum_PYR-GCK GKAIIILNPADPPMIMRDTIFCAIPEDADHAAITQSVKDVVAEVQTYVPG
TH_0370|M.thermoresistible__bu GKAIIILNPAEPPMIMRDTIFCAIPEDADHDAITESIHDVVAEVQTYVPG
MSMEG_4149|M.smegmatis_MC2_155 GKAIIVLNPAEPPLIMRDTVLCLC-DEADETEIEAAVERMVASVAEFVPG
MAB_4374|M.abscessus_ATCC_1997 GKAIIVLNPADPPPLMRDTVFCLV-GDADHGTIRRSVKEMIAEVSTYVPG
Mvan_4392|M.vanbaalenii_PYR-1 GKAIIILNPADPPVIMRDTVLCLT-GDVDQDAVRDSVSTMVEEVSRYVPG
*****:****:** :****::* :.*. : :: :: .* :***
Mb3565c|M.bovis_AF2122/97 YRLLNEPQFDEPSIN-----------SGGQALVTTFVEVEGAGDYLPPYA
Rv3535c|M.tuberculosis_H37Rv YRLLNEPQFDEPSIN-----------SGGQALVTTFVEVEGAGDYLPPYA
MAV_0626|M.avium_104 YRLLNEPQFDDPSLN-----------SGGQALVTTFVEVEGAGDYLPPYA
MMAR_5022|M.marinum_M YRLLNEPQFDEPSIN-----------SGGQAVVTTFVEVEGAGDYLPPYA
MUL_4096|M.ulcerans_Agy99 YRLLNEPQFDEPSIN-----------SGGQAVVTTFVEVEGAGDYLPPYA
Mflv_1521|M.gilvum_PYR-GCK YRLLNEPQFDEPSVV-----------NGGNHLVTIFVEVEGAGDYLPPYA
TH_0370|M.thermoresistible__bu YRLLNEPQFDEPSVV-----------NGGNHLVTTFIEVEGAGDYLPPYA
MSMEG_4149|M.smegmatis_MC2_155 YRLKQKVQFQRYTRN-SPLRLPEQEADFTGLQVSVFLEVEGAAHYLPAYA
MAB_4374|M.abscessus_ATCC_1997 YRLKQDVQFDRVDEP-MRALLRDTTGTVT-TKVSVFLEVEGAGHYLPSYA
Mvan_4392|M.vanbaalenii_PYR-1 YHLKQEVQFDRVSAADVRTLLPAGVGTVS-TQISVFLEVEGAAHYLPAYA
*:* :. **: :: *:*****..***.**
Mb3565c|M.bovis_AF2122/97 GNLDIMTAAATKVGEEIAKETL-VVGGAR----
Rv3535c|M.tuberculosis_H37Rv GNLDIMTAAATKVGEEIAKETL-VVGGAR----
MAV_0626|M.avium_104 GNLDIMTAAATKVGEEIAKETLSVAGGTR----
MMAR_5022|M.marinum_M GNLDIMTAAATKVGEEIAMQTLAVSGGKR----
MUL_4096|M.ulcerans_Agy99 GNLDIMTAAATKVGEEIAKETLAVSGGKR----
Mflv_1521|M.gilvum_PYR-GCK GNLDIMTAAAAKVGEEIARERVATSTTGAQA--
TH_0370|M.thermoresistible__bu GNLDIMTAAATKVGEEIARES-LTATAGGQA--
MSMEG_4149|M.smegmatis_MC2_155 GNLDIMTSAALRT----AERMTELDAIRGK---
MAB_4374|M.abscessus_ATCC_1997 GNLDIMTSAALHT----AESMVRGGDSSQEFGI
Mvan_4392|M.vanbaalenii_PYR-1 GNLDIMTSAALRVGEGIAERLNHAEAPRRSRA-
*******:** :. *