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M. smegmatis MC2 155 MSMEG_3898 (thpD)

annotation: ectoine hydroxylase
coordinates: 3970017 - 3970934
length: 305

TTTQTTQTTPTAETRHDPYPTRLSHAIEPIPRADPTVWGSEADGPLNQKNLDHFSSQGYLVRHGTVTNDW
LPHLRQEMDRIAADLDHDDPRVIREPGGSIRSIFEPHLLSDLVAQVVRLDTVLPVARQLLGSDVYIHQAR
INMMPGFTGTGFYWHSDFETWHAEDGMPAIRAVSCSIALTRNYPYNGSLMVIPGSHQTFYPCVGETPQDN
HDTSLVAQTVGVPDETTLTKAVDHAGIDQFTGAAGSALWFDANLLHGSGSNITPLPRSNVFLVFNSVDNA
LEEPFAAPRRRPEYLAARRVAPVT*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_3898thpD-100% (305)ectoine hydroxylase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97-----
M. gilvum PYR-GCKMflv_4835-1e-11565.42% (295) ectoine hydroxylase
M. tuberculosis H37Rv-----
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_2264c-2e-9658.13% (289) hydroxylase/dioxygenase
M. marinum M-----
M. avium 104-----
M. thermoresistible (build 8)TH_1699thpD1e-13879.79% (287) ectoine hydroxylase
M. ulcerans Agy99-----
M. vanbaalenii PYR-1Mvan_5271-1e-12170.63% (286) ectoine hydroxylase

CLUSTAL 2.0.9 multiple sequence alignment


MSMEG_3898|M.smegmatis_MC2_155      MTTTQTTQTTPTAETRHDPYPTRLSHAIEPIPRADPTVWGSEADGPLNQK
TH_1699|M.thermoresistible__bu      MTQTHVV----------DHYPTRLDHAIAPIPRVDPTVWGTAGDGPLPQR
Mflv_4835|M.gilvum_PYR-GCK          MSAPATLVPE-------DRYPTRLPEPRDPIRREEPTVWGDTFSGPLAES
Mvan_5271|M.vanbaalenii_PYR-1       MSSRHLSQST-------DRYPTRLDTQIDPIAREEPTVWGSAANGPLAAA
MAB_2264c|M.abscessus_ATCC_199      MSAPAIT----------DRYPSRLESEQPPIARKEPVVWGATGSGPLAPP
                                    *:               * **:**     ** * :*.***   .***   

MSMEG_3898|M.smegmatis_MC2_155      NLDHFSSQGYLVRHGTVTNDWLPHLRQEMDRIAADLDHDDPRVIREPGGS
TH_1699|M.thermoresistible__bu      VLDEFSDRGYLIRPDAVPDDWLPRLRHELDRIGADVDDGDPRVIREPSGS
Mflv_4835|M.gilvum_PYR-GCK          DLQSMSDRGYLVRPGTMPEAWLPTLTAELGRMAGEVAPDDPRVIRERDGG
Mvan_5271|M.vanbaalenii_PYR-1       DLDSMASNGYMVRRDAVEAAWLPALTAELDRVAATADPRDPRIIREPGGS
MAB_2264c|M.abscessus_ATCC_199      ALTQMSEQGFLIRPSTVYDATVSALRNEIDRVPAQIGDDDPRIIREAGSQ
                                     *  ::..*:::* .::    :. *  *:.*: .     ***:*** .. 

MSMEG_3898|M.smegmatis_MC2_155      -IRSIFEPHLLSDLVAQVVRLDTVLPVARQLLGSDVYIHQARINMMPGFT
TH_1699|M.thermoresistible__bu      -IRSIFEPHLLSELIDQVVHLDTVLPVARQLLGGDVYIHQARINFMPGFT
Mflv_4835|M.gilvum_PYR-GCK          -IRSVFEPHILSDVLAEVLTMDTVLPVARQLLGSDVYVHQARINMMPGFT
Mvan_5271|M.vanbaalenii_PYR-1       -IRSVFQPHLFSDLISEVVTLDTVLPVARQLLGSDVYLHQARINMMPGFT
MAB_2264c|M.abscessus_ATCC_199      EVRSIFEAHVLSSVVMDVARSPGVLDVAEQLLGGPVYLHQSRINAMPAFR
                                     :**:*:.*::*.:: :*     ** **.****. **:**:*** **.* 

MSMEG_3898|M.smegmatis_MC2_155      GTGFYWHSDFETWHAEDGMPAIRAVSCSIALTRNYPYNGSLMVIPGSHQT
TH_1699|M.thermoresistible__bu      GTGFYWHSDFETWHAEDGMPAIRAVSCSIALTENYPYNGSLMVMPGSHRT
Mflv_4835|M.gilvum_PYR-GCK          GGGFYWHSDFETWHAEDGMPAMRAVSCSIALTENFPFNGSLMVMPGSHRT
Mvan_5271|M.vanbaalenii_PYR-1       GTGFYWHSDFETWHAEDGMPEMRAVSCSIALTQNFPYNGSLMVMPGSHRV
MAB_2264c|M.abscessus_ATCC_199      GRGFYWHSDFETWHTEDGLPQMRTVSCSIALTVNVAYNGTLQVMPGTHRT
                                    * ************:***:* :*:******** * .:**:* *:**:*:.

MSMEG_3898|M.smegmatis_MC2_155      FYPCVGETPQDNHDTSLVAQTVGVPDETTLTKAVDHAGIDQFTGAAGSAL
TH_1699|M.thermoresistible__bu      FYPCVGATPVNNHTTSLVRQDIGVPDQTTLTKVADQHGIDQFTGPPGTAL
Mflv_4835|M.gilvum_PYR-GCK          FYPCVGATPRNNHASSLVRQEIGVPSRQTLTDAAAQHGIDQVTGPAGTAL
Mvan_5271|M.vanbaalenii_PYR-1       FYPCVGATPRDNHASSLVKQEIGVPSHATLTAAADRHGIDQVTGPAGTAL
MAB_2264c|M.abscessus_ATCC_199      FYPCVGATPRDNHRKSLVEQEIGVPSTKTLAEAAVTSGIELFLGQPGDAL
                                    ****** ** :** .*** * :***.  **: ..   **: . * .* **

MSMEG_3898|M.smegmatis_MC2_155      WFDANLLHGSGSNITPLPRSNVFLVFNSVDNALEEPFAAPRRRPEYLAAR
TH_1699|M.thermoresistible__bu      WFDANLLHGSGSNITPFPRSNIFLVFNSVDNALTEPFAAPQRRPEYLAAR
Mflv_4835|M.gilvum_PYR-GCK          WFDCNIMHGSGSNITPYPRSNIFVVFNSVQNQLVSPYRAETPRPEYLAAR
Mvan_5271|M.vanbaalenii_PYR-1       WFDCNIMHGSGSNITPYPRSNIFLVFNSVENRLLAPYRAETPRPEYLAAR
MAB_2264c|M.abscessus_ATCC_199      WFDCNLMHGSGSNISPYPRSNVFLVFNSVENTPQKPFAGYEPRPEYIAAR
                                    ***.*::*******:* ****:*:*****:*    *: .   ****:***

MSMEG_3898|M.smegmatis_MC2_155      RVAPVT-------
TH_1699|M.thermoresistible__bu      TVRPLRPVA----
Mflv_4835|M.gilvum_PYR-GCK          TFRPFNEPVLT--
Mvan_5271|M.vanbaalenii_PYR-1       TSQPFSATALTT-
MAB_2264c|M.abscessus_ATCC_199      DFTPLTPKSPSTP
                                       *.