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MIHQCVDQYICLADNINFNLDGLRNGFWQLTIDGLSWGAIYALVAVGYTLVFGVLRLINFAHSEIFMLGM FGAYFCLDVILGFTPSGNAYNKGIGLTVLYLGIAMLFAMLVSGSAAIGLEFIAYRPLRKRNARALTFLIT AIGMSFVLQEFVHFVLPKLMKGYGGSNAQQPITLVQPKAQFTVFGATVSNVTLVIVVSALILALLTDIAL NRTKFGRGIRAVAQDPTTATLMGVSRERIIMTTFLIGGLLAGAAALLYTLKVPQGIIYSGGFLLGIKAFS AAVLGGIGNLRGALLGGLLLGIMENYGQAVFGTQWRDVVAFVLLVLVLLFRPTGILGESLGKARV
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3248 | - | - | 100% (345) | ABC transporter branched chain amino acid transport permease |
| M. smegmatis MC2 155 | MSMEG_6879 | - | 2e-28 | 29.58% (311) | integral membrane protein of the ABC-type Nat permease for |
| M. smegmatis MC2 155 | MSMEG_2981 | - | 1e-26 | 29.14% (302) | branched-chain amino acid ABC-type transport system, permease |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_3573 | - | 1e-168 | 88.62% (334) | inner-membrane translocator |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | MLBr_00397 | - | 6e-09 | 28.45% (116) | putative transporter protein |
| M. abscessus ATCC 19977 | MAB_2625c | - | 1e-152 | 78.72% (343) | branched chain amino acid ABC transporter |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | - | - | - | - | - |
| M. thermoresistible (build 8) | TH_1081 | - | 1e-163 | 82.61% (345) | ABC transporter branched chain amino acid transport permease |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_2842 | - | 1e-168 | 88.89% (333) | inner-membrane translocator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3573|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2842|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_3248|M.smegmatis_MC2_155 --------------------------------------------------
TH_1081|M.thermoresistible__bu --------------------------------------------------
MAB_2625c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_00397|M.leprae_Br4923 MDHTTKCDAEQYFQAIVTSMADGVIVVDIDGRIESINPAATRILGLRAHD
Mflv_3573|M.gilvum_PYR-GCK ----------------------------------MNLAANINFNVGALVD
Mvan_2842|M.vanbaalenii_PYR-1 ----------------------------------MNLAANINFNVGALVD
MSMEG_3248|M.smegmatis_MC2_155 -------------------------MIHQCVDQYICLADNINFNLDGLRN
TH_1081|M.thermoresistible__bu -------------------------MTHQCVALYTCHAADITFNLQGLRE
MAB_2625c|M.abscessus_ATCC_199 -------------------------MISGWMAQTGVQASTISFDLHGLWS
MLBr_00397|M.leprae_Br4923 VVDMKHGHPFCFYDTDNQRVDLEREVMRVVRREVTTVSKVVGIDQHSGQR
: : :: .
Mflv_3573|M.gilvum_PYR-GCK SFWQLTIDGLSWGA-IYALVAVGYTLVFG---VLRLINFAHSEIFMLGMF
Mvan_2842|M.vanbaalenii_PYR-1 SFWQLTIDGLSWGA-IYALVAVGYTLVFG---VLRLINFAHSEIFMLGMF
MSMEG_3248|M.smegmatis_MC2_155 GFWQLTIDGLSWGA-IYALVAVGYTLVFG---VLRLINFAHSEIFMLGMF
TH_1081|M.thermoresistible__bu GLLQLTIDGLSWGA-IYALVAVGYTLVYG---VLKLINFAHAEVFMLGMF
MAB_2625c|M.abscessus_ATCC_199 SIGQLTIDGLAWGA-IYALVAVGYTLVFG---VLRLINFAHSEVFMLGMF
MLBr_00397|M.leprae_Br4923 LWLSVNVSLLAYKAPPHSALVVSFSDISAHHLSIERLTYEATHDCLTGLA
.:.:. *:: * :: :.*.:: : . :. :.: :. : *:
Mflv_3573|M.gilvum_PYR-GCK GAYFALDVILG--------------------FTPSGNAYSKGVG------
Mvan_2842|M.vanbaalenii_PYR-1 GAYFALDIILG--------------------FTPSGNAYSKGVA------
MSMEG_3248|M.smegmatis_MC2_155 GAYFCLDVILG--------------------FTPSGNAYNKGIG------
TH_1081|M.thermoresistible__bu GSYFCLDVILG--------------------FTPRGNAYDLGIG------
MAB_2625c|M.abscessus_ATCC_199 GAYFALDVVLG--------------------FSPGGNAYNKGVS------
MLBr_00397|M.leprae_Br4923 NRRFAEDQITKSLQHDERSRLAAVLLLDLDDFKVINDSLGHDVGDAVLQT
. *. * : *. .:: . .:.
Mflv_3573|M.gilvum_PYR-GCK ----------------------LTILYLG---------------------
Mvan_2842|M.vanbaalenii_PYR-1 ----------------------LTVLYLG---------------------
MSMEG_3248|M.smegmatis_MC2_155 ----------------------LTVLYLG---------------------
TH_1081|M.thermoresistible__bu ----------------------LTVLYLG---------------------
MAB_2625c|M.abscessus_ATCC_199 ----------------------LTVLYLG---------------------
MLBr_00397|M.leprae_Br4923 VAQRLRSAVRPDDVVARLGGDEFIVLLRGPLSDMNANDVAKRLHTTLSES
: :* *
Mflv_3573|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2842|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_3248|M.smegmatis_MC2_155 --------------------------------------------------
TH_1081|M.thermoresistible__bu --------------------------------------------------
MAB_2625c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_00397|M.leprae_Br4923 LVVDQLTVPIGASVGILEVRPDDRRRAADILRDADSAMYAAKNKKQCAVT
Mflv_3573|M.gilvum_PYR-GCK ------VAMLFAMAVSGSAAIGLEFIAYRPLRKRNARALTFLITAIGMSF
Mvan_2842|M.vanbaalenii_PYR-1 ------IAMLFAMLVSGGAAVGLEFVAYRPLRKRNARSLTFLITAIGMSF
MSMEG_3248|M.smegmatis_MC2_155 ------IAMLFAMLVSGSAAIGLEFIAYRPLRKRNARALTFLITAIGMSF
TH_1081|M.thermoresistible__bu ------IAMLFAIAVSGTAAAGLEFIAYRPLRRRNAARLSFLITAIGMSF
MAB_2625c|M.abscessus_ATCC_199 ------VAMLVAMAVSATTALGLEAVAYRPLRRRGARPLTFLITAIGMSF
MLBr_00397|M.leprae_Br4923 PQQLVPFVALIALFVFFTAAAGAKFYAPSNLLVILQQTVVLAIVGYGMTF
.. *.*: * :* * : * * : : *.. **:*
Mflv_3573|M.gilvum_PYR-GCK VLQQ----------------------------------------------
Mvan_2842|M.vanbaalenii_PYR-1 VLQQ----------------------------------------------
MSMEG_3248|M.smegmatis_MC2_155 VLQE----------------------------------------------
TH_1081|M.thermoresistible__bu VLQE----------------------------------------------
MAB_2625c|M.abscessus_ATCC_199 VIQE----------------------------------------------
MLBr_00397|M.leprae_Br4923 VIMAGSVDLSVGSIVALTGVTAALVAAQNQFAAIVTALLVGLAAGMVNGI
*:
Mflv_3573|M.gilvum_PYR-GCK -FVLFILPKIIPGYGGPNAQQPIVLVQPRTQFEF-----------FGVAI
Mvan_2842|M.vanbaalenii_PYR-1 -FVLFILPKLIPGYGGPNAQQPIVLVQPKTQFEF-----------FGVAI
MSMEG_3248|M.smegmatis_MC2_155 -FVHFVLPKLMKGYGGSNAQQPITLVQPKAQFTV-----------FGATV
TH_1081|M.thermoresistible__bu -FVHFILPKILDGYGGSNAQQPIRLVTPETQFTL-----------GDVRV
MAB_2625c|M.abscessus_ATCC_199 -FVHWVLPKIAKGYGGSNAQQPLMLVTPRPVWTFGPFDVSGHHIPFQATI
MLBr_00397|M.leprae_Br4923 VFAYGKIPSFVSTLGMLQVCRGITLMISDSSAKPMP-------FHGILGA
*. :*.: * :. : : *: . .
Mflv_3573|M.gilvum_PYR-GCK SNITLVIISAALVLAVLTDVAINRTKFGRGIRAVAQDPTTATLMGVSRER
Mvan_2842|M.vanbaalenii_PYR-1 SNITIVIVASALVLAVLTDIAINRTKFGRGIRAVAQDPTTATLMGVSRER
MSMEG_3248|M.smegmatis_MC2_155 SNVTLVIVVSALILALLTDIALNRTKFGRGIRAVAQDPTTATLMGVSRER
TH_1081|M.thermoresistible__bu SNVTLIIVFAALVLALITDVVINRTRLGRGIRAVAQDPDTATLMGVSRER
MAB_2625c|M.abscessus_ATCC_199 TNVTVVVVAAALVLAFVTDIAINHTKFGRGIRAVAQDSTTATLMGVSRER
MLBr_00397|M.leprae_Br4923 MGAMPWILIVCLFVTILAGILFQFTMFGRWVKAIGGNERVATLAGVPTRG
. :: .*.::.::.: :: * :** ::*:. : .*** **. .
Mflv_3573|M.gilvum_PYR-GCK IIMTTFLIGGLLAGAAALLYTLKVPQGIIYSGG-----FLLGIKAFSAAV
Mvan_2842|M.vanbaalenii_PYR-1 IIMTTFLIGGLLAGAAALLYTLKVPQGIIYSGG-----FLLGIKAFSAAV
MSMEG_3248|M.smegmatis_MC2_155 IIMTTFLIGGLLAGAAALLYTLKVPQGIIYSGG-----FLLGIKAFSAAV
TH_1081|M.thermoresistible__bu VILTTFVIGGLLAGAAALLYTLKMPQAIIYSGG-----FLLGIKAFTAAV
MAB_2625c|M.abscessus_ATCC_199 IIMATFVIGGLLAGAAALLYTLKVPQGIIYSGG-----FLLGIKAFSAAV
MLBr_00397|M.leprae_Br4923 IKVAIFAICGLTAGLGGIVLASRLGAGTPTAATGFEIDVIAAVVIGGTPL
: :: * * ** ** ..:: : :: . :. .: .: :.:
Mflv_3573|M.gilvum_PYR-GCK LGGIGNLRGALLGGLLLGVMEN-YGQAVFGTQWRDVVAFVLLVLVLLVRP
Mvan_2842|M.vanbaalenii_PYR-1 LGGIGNLRGALLGGLLLGVMEN-YGQAVFGTQWRDVVAFVLLVLVLLVRP
MSMEG_3248|M.smegmatis_MC2_155 LGGIGNLRGALLGGLLLGIMEN-YGQAVFGTQWRDVVAFVLLVLVLLFRP
TH_1081|M.thermoresistible__bu LGGIGNLRGALLGGLLLGVMEN-YGQAVFGTQWRDVVAFVLLVLVLFFRP
MAB_2625c|M.abscessus_ATCC_199 LGGIGNLRGALLGGLILGVMEN-YGQAVFGTQWRDVVAFVLLVLVLMFRP
MLBr_00397|M.leprae_Br4923 TGGLGRLSGTLIGAIIISMLSNGMVFMGVGNAASQIIKGIMLAAAVFVFL
**:*.* *:*:*.:::.::.* .*. ::: ::*. .::.
Mflv_3573|M.gilvum_PYR-GCK TGILGESLGKARV
Mvan_2842|M.vanbaalenii_PYR-1 TGILGESLGKARA
MSMEG_3248|M.smegmatis_MC2_155 TGILGESLGKARV
TH_1081|M.thermoresistible__bu TGILGESLGKARV
MAB_2625c|M.abscessus_ATCC_199 TGILGESLGRAKA
MLBr_00397|M.leprae_Br4923 Q---RRKIGIIK-
..:* :