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PGYPGGWSGGYPGAHPPPPRTNGMAIAALVCAFLFAPAGIVFGHLSLSQIKRTGEQGRSLAIAGLVISYV FTVLTVVAVIVSILLTMAAVQTVDRRPGGPTYDAAPQNALPAFDPPPNLGLDCQYPPTTEPAAKPARPPR TGTVPTEPATVSAGIRTNHGSIGLRLANGRSPCTVNSFASLAQQGFYDNTPCHRLSTGQMAVLQCGDPTG KGTGGPGYRFANEYPTNQYRLSDPALRTPVVYPRGTVATANAGPGSNGSQFFLVYQDSPLPPTYTVFGEV DRTGLRTLDAIASAGVADGGDDGPPAEPVTITEASLD*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2973 | - | - | 100% (318) | peptidyl-prolyl cis-trans isomerase |
| M. smegmatis MC2 155 | MSMEG_2974 | - | 2e-82 | 56.67% (270) | peptidyl-prolyl cis-trans isomerase, cyclophilin-type |
| M. smegmatis MC2 155 | MSMEG_0024 | - | 6e-22 | 39.13% (184) | peptidyl-prolyl cis-trans isomerase B |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2613 | ppiB | 2e-82 | 55.64% (275) | peptidyl-prolyl cis-trans isomerase B |
| M. gilvum PYR-GCK | Mflv_3811 | - | 1e-82 | 56.99% (279) | peptidyl-prolyl cis-trans isomerase, cyclophilin type |
| M. tuberculosis H37Rv | Rv2582 | ppiB | 5e-83 | 56.00% (275) | peptidyl-prolyl cis-trans isomerase B |
| M. leprae Br4923 | MLBr_00492 | ppiB | 5e-83 | 56.03% (282) | putative peptidyl-prolyl cis-trans isomerase |
| M. abscessus ATCC 19977 | MAB_2874 | - | 2e-70 | 48.29% (292) | peptidyl-prolyl cis-trans isomerase |
| M. marinum M | MMAR_2125 | ppiB | 1e-84 | 56.43% (280) | peptidyl-prolyl cis-trans isomerase B PpiB |
| M. avium 104 | MAV_3462 | - | 8e-82 | 55.04% (278) | peptidyl-prolyl cis-trans isomerase, cyclophilin-type |
| M. thermoresistible (build 8) | TH_2333 | ppiB | 1e-80 | 54.48% (279) | PROBABLE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE B PPIB |
| M. ulcerans Agy99 | MUL_1730 | ppiB | 7e-85 | 56.43% (280) | peptidyl-prolyl cis-trans isomerase B PpiB |
| M. vanbaalenii PYR-1 | Mvan_2588 | - | 1e-84 | 56.07% (280) | peptidyl-prolyl cis-trans isomerase, cyclophilin type |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3811|M.gilvum_PYR-GCK ------------------------------MPTNEQRRATAKRKLERQLE
Mvan_2588|M.vanbaalenii_PYR-1 --------MAAQRQLAHSVPTGSTARRTPAVPTNEQRRATAKRKLERQLE
MAB_2874|M.abscessus_ATCC_1997 ------------------------------MPTNEQRRQTAKRKLERQLE
Mb2613|M.bovis_AF2122/97 MGHLTPVAAPRLACA--------------FVPTNAQRRATAKRKLERQLE
Rv2582|M.tuberculosis_H37Rv MGHLTPVAAPRLACA--------------FVPTNAQRRATAKRKLERQLE
MMAR_2125|M.marinum_M ------------------------------MPTNQQRRATAKRKLERQLE
MUL_1730|M.ulcerans_Agy99 MGCLTRVSALTLAWAGHSARFTGQAGRTSAVPTNQQRRATAKRKLERQLE
MAV_3462|M.avium_104 ------------------------------MPTNEQRRANAKRKLERQLE
MLBr_00492|M.leprae_Br4923 ------------------------------MPTNEQRRATAKRKLKRQLE
TH_2333|M.thermoresistible__bu -----------------------------VPTTNAERREAAKRKLEEQLA
MSMEG_2973|M.smegmatis_MC2_155 --MPGYPGGWSGGYPGAHPPPPRTNGMAIAALVCAFLFAPAGIVFGHLSL
. * : .
Mflv_3811|M.gilvum_PYR-GCK HRAERERKR-RQYTIIGSAVGGVLVVAAVVATIVLVNRDSGTETASASTS
Mvan_2588|M.vanbaalenii_PYR-1 NRAERERKR-RLYTIIGSAVAAVVVIAAVVATIVITNRDSGTQTASTATS
MAB_2874|M.abscessus_ATCC_1997 NRAERARKQ-RIWAISGVAVLAVVVAVAITAWFAISKGDK-TDTAHDTAS
Mb2613|M.bovis_AF2122/97 RRAKQAKRR-RILTIVGGSLAAVAVIVAVVFTVVVNKDDHQSTTSATPTD
Rv2582|M.tuberculosis_H37Rv RRAKQAKRR-RILTIVGGSLAAVAVIVAVVVTVVVNKDDHQSTTSATPTD
MMAR_2125|M.marinum_M RRAKQAKRR-RILMIVGSAVAAVAVIAAVVVVVVINKGDHKTTASASPSS
MUL_1730|M.ulcerans_Agy99 RRAKQAKRR-RILMIVGSAVAAVAVIAAVVVVVVINKGDHKTTASASPSS
MAV_3462|M.avium_104 RRAKQARTR-RILLIAAGSIVAVAVIAAVVVTVLNNRHEHKASTAAPSTS
MLBr_00492|M.leprae_Br4923 RRAKQARWR-RVLLISGGVVVAVAVIITVVATVVISKLGHKHDTASSTAS
TH_2333|M.thermoresistible__bu RREARARRN-RLLAVIGSVVAVIALVGAAVYVFVLDRDDAESDTTAQSET
MSMEG_2973|M.smegmatis_MC2_155 SQIKRTGEQGRSLAIAGLVISYVFTVLTVVAVIVSILLTMAAVQTVDRRP
: : . * : . : : : . . :
Mflv_3811|M.gilvum_PYR-GCK TTETS-------SPFDVP--PPAEAVTLPEFVAPEGLGGNCQYP-EAEPA
Mvan_2588|M.vanbaalenii_PYR-1 TTQTS-------SPFDVP--PPTEAGALPEFVAAEGLGSDCQYPKSAEAA
MAB_2874|M.abscessus_ATCC_1997 TTPVSTVDAPPTSSLPTPDEPPLAGPALPKFVPSAEVGANCQYRPSGKAS
Mb2613|M.bovis_AF2122/97 SASTS--------PPQAA-----TAPPLPPFKPSANLGANCQYPPSPDKA
Rv2582|M.tuberculosis_H37Rv SASTS--------PPQAA-----TAPPLPPFKPSANLGANCQYPPSPDKA
MMAR_2125|M.marinum_M SEPTSS-----AAAPADD-----SVPPLPAFKPSANLGANCQYPASPDKA
MUL_1730|M.ulcerans_Agy99 SEPTSS-----AAAPADD-----SVPPLPAFKPSANLGANCQYPASPDKA
MAV_3462|M.avium_104 TSAPET-----TTPGQPS-----QVPPLPPFKPSADVGANCQYPPSPEPA
MLBr_00492|M.leprae_Br4923 NSLTAT-----KTPAVTP-----SVLPLPSFQPSTNLGVNCQYPPSADKA
TH_2333|M.thermoresistible__bu PDTQLAG----PTPLPAG-----GPGQLPAFNPPPDLGADCQYPAAATPA
MSMEG_2973|M.smegmatis_MC2_155 GGPTYD---------AAP------QNALPAFDPPPNLGLDCQYPPTTEPA
** * .. :* :*** :
Mflv_3811|M.gilvum_PYR-GCK S-KPNNAPRTGKVPTEPAQVSASMETDQGNIGLQLDNGKSPCTVNSFASL
Mvan_2588|M.vanbaalenii_PYR-1 S-KSNNPPRSGKVPTEPALVSASMATDQGNIGLQLDNGKSPCTVNSFASL
MAB_2874|M.abscessus_ATCC_1997 KTIEKQIPRTGKIPTDPATLTASMKTSQGNIGLVLDNAKAPCTVNSFASL
Mb2613|M.bovis_AF2122/97 V-KPVKLPRTGKVPTDPAQVSVSMVTNQGNIGLMLANNESPCTVNSFVSL
Rv2582|M.tuberculosis_H37Rv V-KPVKLPRTGKVPTDPAQVSVSMVTNQGNIGLMLANNESPCTVNSFVSL
MMAR_2125|M.marinum_M A-KPAKPPRSGKVPTEPAQVSASMMTSQGKVGLMLANNESPCTVNSFASL
MUL_1730|M.ulcerans_Agy99 A-KPAKPPRSGKVPTEPAQVSASMMTSQGKVGLMLANNESPCTVNSFASL
MAV_3462|M.avium_104 A-KQVKPPRTGKVPTDPAQVSASMVTNQGHIGLMLANNESPCTVNSFASL
MLBr_00492|M.leprae_Br4923 A-KPVKPPRAGKVPTDPATVSASMATNQGNIGLLLNNAESPCTVNSFASL
TH_2333|M.thermoresistible__bu S-KEVNPPRTGKVPTDPEWVSVSMSTNQGNLGLWLDNGKAPCTVNSFVSL
MSMEG_2973|M.smegmatis_MC2_155 A-KPARPPRTGTVPTEPATVSAGIRTNHGSIGLRLANGRSPCTVNSFASL
. **:*.:**:* ::..: *.:* :** * * .:*******.**
Mflv_3811|M.gilvum_PYR-GCK AQQGYFANTPCHRLTTSDSLGVLQCGDPTGEGTGGPGYQFDNEYPTDQYQ
Mvan_2588|M.vanbaalenii_PYR-1 AQQGFFNDTPCHRLTTSDSLGVLQCGDPTGEGTGGPGYEFANEYPTDQYQ
MAB_2874|M.abscessus_ATCC_1997 AQGGYFDNTVCHRMTSGG-LSVLQCGDPTATGSGGPGYEFDNEYPTTQYK
Mb2613|M.bovis_AF2122/97 AQQGFFKGTTCHRLTTSPMLAVLQCGDPKGDGTGGPGYQFANEYPTDQYS
Rv2582|M.tuberculosis_H37Rv AQQGFFKGTTCHRLTTSPMLAVLQCGDPKGDGTGGPGYQFANEYPTDQYS
MMAR_2125|M.marinum_M AQQGFFKDTKCHRLTTSPTLSVLQCGDPKGDGTGGPGYQFANEYPTDQYP
MUL_1730|M.ulcerans_Agy99 AQQGFFKDTKCHRLTTSPTLSVLQCGDPKGDGTGGPGYQFANEYPTDQYP
MAV_3462|M.avium_104 IGQKYFDNTKCHRLTTSPSLGVLQCGDPKGEGTGGPGYQFANEYPTDQYP
MLBr_00492|M.leprae_Br4923 TGQGFFNNTKCHRLTTSLMLGVLQCGDPKVDGTGGPGYKFANEYPTDQYP
TH_2333|M.thermoresistible__bu AQQGYFDDTTCHRLTATPALSVLQCGDPTGTGAGGPGYQFGNEYPTNQYP
MSMEG_2973|M.smegmatis_MC2_155 AQQGFYDNTPCHRLSTGQ-MAVLQCGDPTGKGTGGPGYRFANEYPTNQYR
:: .* ***::: :.*******. *:*****.* ***** **
Mflv_3811|M.gilvum_PYR-GCK PDDPKLGEPVVYPRGTLAMAN-AGPGTNGSQFFLVYKDSQLPPQYTVFGT
Mvan_2588|M.vanbaalenii_PYR-1 PDDPALGAPVVYPRGTLAMAN-AGPGTNGSQFFLVYKDSQLPPQYTVFGT
MAB_2874|M.abscessus_ATCC_1997 ADDPAAQQAVVYPAGTLAMAN-AGPGTNGSQFFMVYKDSKLPPQYTVFGT
Mb2613|M.bovis_AF2122/97 ANDPKLNEPVIYPRGTLAMAN-AGPNTNSSQFFMVYRDSKLPPQYTVFGT
Rv2582|M.tuberculosis_H37Rv ANDPKLNEPVIYPRGTLAMAN-AGPNTNSSQFFMVYRDSKLPPQYTVFGT
MMAR_2125|M.marinum_M PNDPALRQPVIYPRGTLAMAN-AGPDTNSSQFFMVYRDSQLPPQYTVFGT
MUL_1730|M.ulcerans_Agy99 PNDPALRQPVIYPRGTLAMAN-AGPDTNSSQFFMVYRDSQLPPQYTVFGT
MAV_3462|M.avium_104 PNDPKAQQPVLYPRGTLAMAN-ARPGTNGSQFFMVYKDSQLPPQYTVFGK
MLBr_00492|M.leprae_Br4923 PNDPKLKQPVLYPRGTLAMAN-SGPNTNGSQFFLVYHDSQLPPEYTVFGT
TH_2333|M.thermoresistible__bu QGDPALQEPVTYPRGALAMAHSAGQHNNGSQFFLVYQDSQLPPDYTVFGV
MSMEG_2973|M.smegmatis_MC2_155 LSDPALRTPVVYPRGTVATAN-AGPGSNGSQFFLVYQDSPLPPTYTVFGE
.** .* ** *::* *: : .*.****:**:** *** *****
Mflv_3811|M.gilvum_PYR-GCK IDETGLETLDKIAEAGVDGGGP---DGAPKLPVTVKNIQLD
Mvan_2588|M.vanbaalenii_PYR-1 IDETGLQTLDKIAAAGVAGGGP---DGAPQLATTVKSIQLD
MAB_2874|M.abscessus_ATCC_1997 IDKTGMDTLAKIAKNGIKPGARGAGDGEPAQEVKIIDLQLD
Mb2613|M.bovis_AF2122/97 IQADGLTTLDKIAKAGVAGGGE---DGKPATEVTITSVLLD
Rv2582|M.tuberculosis_H37Rv IQADGLTTLDKIAKAGVAGGGE---DGKPATEVTITSVLLD
MMAR_2125|M.marinum_M IQADGLETLDKIAKAGVAGGGE---DGPPALDVTIKSVFLD
MUL_1730|M.ulcerans_Agy99 IQADGLETLDKIAKAGVAGGGE---DGPPALDVTIKSVFLD
MAV_3462|M.avium_104 IQDDGLATLDKIAKAGVAGGGE---DGAPATEVTITSVLLD
MLBr_00492|M.leprae_Br4923 IQADGLATLDKIAKGGIASGGD---DGPPATEVTIESLRLD
TH_2333|M.thermoresistible__bu IDETGLETLDKIAAAGIAGNAM---DGAPAEEVRVTSILMD
MSMEG_2973|M.smegmatis_MC2_155 VDRTGLRTLDAIASAGVADGGD---DGPPAEPVTITEASLD
:: *: ** ** *: .. ** * . : . :*