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PLLELSDLTVTYPGDGITPKIALGHVNLSLAAGEFAAIVGESGSGKTTLVNTVLGLLPRTATVTADTLAL DGAGILGLTEREWSRIRGTTVGLVPQDPGASLNPVRTIGSQIAEIFDLRDEKLSRAERRRRCIDLLEQVE IDQPERRLRQHPGELSGGMRQRVLIAIAFGLNPKLLVADEPTSALDVTVQAQVLRVFDRLVAEHGTTVLF VTHDIGVATDHASRVVVMRKGQIVEDAPVDDIVSRPSSEYTAALVRRIGAGITPPAAAHENVHAPADEVI RVAHVSKEFRLDRRHRHRAVDDISFTVRRGETLALVGESGSGKSTTAKMIIGLTQPTRGSIEVLGHDITR LGHRDRRAHWKNIQFVYQNPDSALDPRWSVREVLESPLRAYHLDNRDQRIAEALDNVNLSRDKLTRRTVE LSGGERQRVAIARALVVQPQIILLDEPLSALDVVTQDQILGLLRELQDNLGLTYLFISHDLSVVQQLSHR VVVLKAGQVAESGDTAAVFSAPTSPYTRALIDAVPGRRLARLALAS*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. smegmatis MC2 155 | MSMEG_2844 | - | - | 100% (537) | ABC transporter, ATP-binding protein |
M. smegmatis MC2 155 | MSMEG_4388 | - | e-120 | 46.17% (535) | ABC transporter ATP-binding protein |
M. smegmatis MC2 155 | MSMEG_4098 | - | e-120 | 46.08% (549) | ABC transporter ATP-binding protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3687c | dppD | 1e-117 | 44.98% (538) | peptide ABC transporter ATP-binding protein |
M. gilvum PYR-GCK | Mflv_2758 | - | 8e-95 | 39.33% (534) | AAA ATPase |
M. tuberculosis H37Rv | Rv3663c | dppD | 1e-117 | 44.98% (538) | peptide ABC transporter ATP-binding protein |
M. leprae Br4923 | MLBr_01122 | - | 1e-105 | 39.90% (604) | putative ABC transport protein, ATP-binding component |
M. abscessus ATCC 19977 | MAB_0722 | - | 1e-106 | 42.23% (528) | putative oligopeptide ABC transporter, ATP-binding protein |
M. marinum M | MMAR_5151 | dppD | 1e-112 | 44.83% (551) | dipeptide-transport ATP-binding protein ABC transporter DppD |
M. avium 104 | MAV_3418 | - | 0.0 | 68.77% (538) | ABC transporter, ATP-binding protein DppD |
M. thermoresistible (build 8) | TH_4070 | - | 1e-107 | 41.64% (538) | PUTATIVE ABC transporter related |
M. ulcerans Agy99 | MUL_4237 | dppD | 1e-112 | 44.83% (551) | dipeptide-transport ATP-binding protein ABC transporter DppD |
M. vanbaalenii PYR-1 | Mvan_3776 | - | 1e-101 | 41.33% (513) | ABC transporter-related protein |
CLUSTAL 2.0.9 multiple sequence alignment MSMEG_2844|M.smegmatis_MC2_155 ------MPLLELSDLTVTYPGDG-ITPKIALGHVNLSLAAGEFAAIVGES MAV_3418|M.avium_104 ----MGPPLLDVSGLTVTYPG---AVPRVALDRVDLAVSSGEFVAVVGES Mb3687c|M.bovis_AF2122/97 -MSVPAAPLLSVEGLEVTFGTD---APAVCG--VDLAVRSGQTVAVVGES Rv3663c|M.tuberculosis_H37Rv -MSVPAAPLLSVEGLEVTFGTD---APAVCG--VDLAVRSGQTVAVVGES MMAR_5151|M.marinum_M -MSTAAAPLLSVHGLQVRFGTD---EPVVAG--MDLSVYRGQTVAVVGES MUL_4237|M.ulcerans_Agy99 -MSTAAAPLLSVHGLQVRFGTD---EPVVAG--MDLSVYRGQTVAVVGES MLBr_01122|M.leprae_Br4923 -----MSPLLEVTDLAVTFETN--GEPVTAVRGISYRINAGEVVAMVGES Mflv_2758|M.gilvum_PYR-GCK ------MTVLNVQDLSVRIGART------IVDSVSFAVEREKTVGIVGES Mvan_3776|M.vanbaalenii_PYR-1 ------MTVLSVDNLRVRIGART------IVDGVSFDVAREKTVGIVGES TH_4070|M.thermoresistible__bu ---VVTGPVLDVRDLRVRIGRRE------IVRGVSFAVARGQTLGIVGES MAB_0722|M.abscessus_ATCC_1997 MSHVEASSALSFRSLSVTFSTDSG--PVSAVDDVSFDVKPGEVLAVVGES . *.. .* * :. : : .:**** MSMEG_2844|M.smegmatis_MC2_155 GSGKTTLVNTVLGLLPRTATVTADTLALDG----AGILGLTEREWSRIRG MAV_3418|M.avium_104 GSGKTTLANAVVGLLPAAARITAGSLTIAG----RDVLGLSERQWCRLRG Mb3687c|M.bovis_AF2122/97 GSGKSTTAAAILGLLPAGGRITAGRVVFDG----RDITGADAKRLRSIRG Rv3663c|M.tuberculosis_H37Rv GSGKSTTAAAILGLLPAGGRITAGRVVFDG----RDITGADAKRLRSIRG MMAR_5151|M.marinum_M GSGKSTAAAAILGLLAPGGRITAGRIIFDG----RDITSADRRVMRTIRG MUL_4237|M.ulcerans_Agy99 GSGKSTAAAAILGLLAPGGRITAGRIIFDG----RDITSADRRVMRTIRG MLBr_01122|M.leprae_Br4923 GSGKSAAAMAVVGLLPEYAQVRG-SVRLHN----TELVGLADKTMSRFRG Mflv_2758|M.gilvum_PYR-GCK GSGKTMTVLAATGLLDAPGARVSGVSTLGG---EVHLVGATPKALRSVHG Mvan_3776|M.vanbaalenii_PYR-1 GSGKTMTVLAATGLLDAPGARVSGSSTLTGADEPVQLVGASPRVLRVVHG TH_4070|M.thermoresistible__bu GSGKSMTVLAAAGLLDAPGAVVTGSATVGG----VELIGAPPRLLRSVHG MAB_0722|M.abscessus_ATCC_1997 GSGKSVSSRTAIRLLPDT-ARITGSVLLDG----RDVTKLSGRELAAMRG ****: : ** . . : : .:* MSMEG_2844|M.smegmatis_MC2_155 TTVGLVPQDPGASLNPVRTIGSQIAEIFDLRDEKLSRAERRRRCIDLLEQ MAV_3418|M.avium_104 STVGLVPQDPATSLNPVRSIGSQIAEIFPLKGERLSRREARRRCIELLDR Mb3687c|M.bovis_AF2122/97 REIGYVPQDPMTNLNPVWKVGFQVTEALRANTD---GRAARRRAVELLAE Rv3663c|M.tuberculosis_H37Rv REIGYVPQDPMTNLNPVWKVGFQVTEALRANTD---GRAARRRAVELLAE MMAR_5151|M.marinum_M REIGYVPQDPMTNLNPVWKVGFQIREALRANTD---GRDARRRTVELLAQ MUL_4237|M.ulcerans_Agy99 REIGYVPQDPMTNLNPVWKVGFQIREALRANTD---GRDARRRTVELLAQ MLBr_01122|M.leprae_Br4923 KAIGTVFQDPMSALTPVYTVGDQITEAIKVHQPRVGKKAAHRRAVELLEL Mflv_2758|M.gilvum_PYR-GCK ARIGFVFQDPGTSLNPLLTLERQITESLETHRN-LTRRAANDRALELLEA Mvan_3776|M.vanbaalenii_PYR-1 ARIGFVFQDPGTSLNPLLTLERQITESLEKHRH-LTRRAAKDRALELLEA TH_4070|M.thermoresistible__bu NRVGFVFQDPGTSLNPLLTLERQITEVLEAHRG-MTRRAARGRALELLTA MAB_0722|M.abscessus_ATCC_1997 KDIAMVFQEPGAALDPLFTIGYQVAEAVRAHSD-MSRVQARARVIELLKL :. * *:* : * *: .: *: * . . . * ::** MSMEG_2844|M.smegmatis_MC2_155 VEIDQPERRLRQHPGELSGGMRQRVLIAIAFGLNPKLLVADEPTSALDVT MAV_3418|M.avium_104 VEIDRPAQRLKQYPGELSGGMRQRVLIAIAFALNPGLLIADEPTSALDVT Mb3687c|M.bovis_AF2122/97 AGLPDPAKQAGRYPHQLSGGMCQRALIAIGLAGRPRLLIADEPTSALDVT Rv3663c|M.tuberculosis_H37Rv AGLPDPAKQAGRYPHQLSGGMCQRALIAIGLAGRPRLLIADEPTSALDVT MMAR_5151|M.marinum_M AGMPDPDKHAQRYPHQLSGGMCQRALIAIGLAGRPALLIADEPTSALDVT MUL_4237|M.ulcerans_Agy99 AGMPDPDKHAQRYPHQLSGGMCQRALIAIGLAGRPALLIADEPTSALDVT MLBr_01122|M.leprae_Br4923 VGITQPDRRARAFPHELSGGERQRVVIATAIANDPDLLICDEPTTALDVT Mflv_2758|M.gilvum_PYR-GCK VGLPEPQMRLHAYPHQLSGGQRQRVMIAIALACDPELLIADEPTTALDVT Mvan_3776|M.vanbaalenii_PYR-1 VGLPEPQMRLHAYPHQLSGGQRQRVMIAIALACDPELLVADEPTTALDVT TH_4070|M.thermoresistible__bu VGLPDPAARLRSYPHQLSGGQRQRVMIAIALACDPEVLIADEPTTALDVT MAB_0722|M.abscessus_ATCC_1997 VRLPDPERRYDCYPHQLSGGQKQRVVIAIAIACDPKVIIADEPTTALDVT . : * : .* :**** **.:** .:. * :::.****:***** MSMEG_2844|M.smegmatis_MC2_155 VQAQVLRVFDRLVAEHGTTVLFVTHDIGVATDHASRVVVMRKGQIVEDAP MAV_3418|M.avium_104 VQRHVLAVFDRLVAEQRTTVVFITHDIGVATDHASRIVVMRGGVVVEDAP Mb3687c|M.bovis_AF2122/97 VQRQVLDHLQGLTDELGTALLLITHDLALAAQRAEAVVVVRRGVVVESGA Rv3663c|M.tuberculosis_H37Rv VQRQVLDHLQGLTDELGTALLLITHDLALAAQRAEAVVVVRRGVVVESGA MMAR_5151|M.marinum_M VQRQVLDHLQRRTDELGTALLLITHDLALAAERAESVLVVHHGVVVESGT MUL_4237|M.ulcerans_Agy99 VQRQVLDHLQRRTDEVGTALLLITHDLALAAERAESVLVVDHGVVVESGT MLBr_01122|M.leprae_Br4923 VQAQILEVLKTARDVTGAGVLIITHDLGVVTEFADQALVMYAGRVVESAQ Mflv_2758|M.gilvum_PYR-GCK TQAQIIELVRTLQRDFGTAVVWISHDLGVIGQVADDVTVMRNGIAVEQAP Mvan_3776|M.vanbaalenii_PYR-1 TQSQIIELVRELQRDFGTAVVWISHDLGVIGQVADEVTVMRNGVTVEQAP TH_4070|M.thermoresistible__bu TQAQIIELVRELQRDFGTAVVWISHDLGVIGEVADEVTVLRHGAAVEQAH MAB_0722|M.abscessus_ATCC_1997 VQAEILELLRDLRDRIGSAIVLITHNMGVVADIADRVVVMKQGKVVEIAP .* .:: . : :: ::*::.: : *. *: * ** . MSMEG_2844|M.smegmatis_MC2_155 VDDIVSRPSSEYTA-------ALVRRIGAGITPPAAAHENV--------- MAV_3418|M.avium_104 AEAIVAAPRTEYAA-------HLVRRLTA---PAPAAAP----------- Mb3687c|M.bovis_AF2122/97 AQSILQSPQHEYTR-------RLVAAAPSLTARSRRPPESR--------- Rv3663c|M.tuberculosis_H37Rv AQSILQSPQHEYTR-------RLVAAAPSLTARSRRPPESR--------- MMAR_5151|M.marinum_M ASDILRSPQHEYTK-------RLVAAAPSLTVRDPRRAPARG-------- MUL_4237|M.ulcerans_Agy99 ASDILRSPQHEYTK-------RLVAAAPSLTVRDPRRAPARG-------- MLBr_01122|M.leprae_Br4923 VSTLYRERQMPYTVGLLGSVPRLDATQGTRLVPIPGAPPSLAGLQQECPF Mflv_2758|M.gilvum_PYR-GCK IMAVFDNPRDDYTR-------DLLAARPVLERAGP--------------- Mvan_3776|M.vanbaalenii_PYR-1 IMEVFDRPREEYTR-------GLLAARPVLDRAGP--------------- TH_4070|M.thermoresistible__bu IAEVFERPRHPYTR-------ELLHARPRLGVGGP--------------- MAB_0722|M.abscessus_ATCC_1997 VERLFAEPAEPYTR-------VLLAAVPHLGQGDPEHGA----------- : *: * MSMEG_2844|M.smegmatis_MC2_155 -------------------------------------------------- MAV_3418|M.avium_104 -------------------------------------------------- Mb3687c|M.bovis_AF2122/97 ------------------------------------------------SR Rv3663c|M.tuberculosis_H37Rv ------------------------------------------------SR MMAR_5151|M.marinum_M ---------------------------------------------PVPGG MUL_4237|M.ulcerans_Agy99 ---------------------------------------------PVPGG MLBr_01122|M.leprae_Br4923 APRCPLVVDECRLREPELVEVRAGHRTACIRTDQVSGRSAADIYGINTDT Mflv_2758|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3776|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_4070|M.thermoresistible__bu -------------------------------------------------- MAB_0722|M.abscessus_ATCC_1997 -------------------------------------------------- MSMEG_2844|M.smegmatis_MC2_155 -HAPAD---EVIRVAHVSKEFRLD-----RRHR--HRAVDDISFTVRRGE MAV_3418|M.avium_104 --AGSE---DVIEVAGVAKEFRLG-----ARAR--HTAVAEVAFTVRRGE Mb3687c|M.bovis_AF2122/97 ATTQAG---DILVVSELTKIYRESRGAPWRRVE--SRAVDGVSFRLPRAS Rv3663c|M.tuberculosis_H37Rv ATTQAG---DILVVSELTKIYRESRGAPWRRVE--SRAVDGVSFRLPRAS MMAR_5151|M.marinum_M ADQPAGGCGDILSVSELTKIYRESRGAPWRRGE--FRAVDSVSFRLRRAS MUL_4237|M.ulcerans_Agy99 ADQPAGGCGDILSVSELTKIYRESRGAPWRRGE--FRAVDSVSFRLRRAS MLBr_01122|M.leprae_Br4923 RTSATSDSSVVVRVRDLVKTYRLTKGVGLRRAIGEIRAVNGVSFELQQGR Mflv_2758|M.gilvum_PYR-GCK --GPVTDAETLLDVDGLDVSFAVS--SPVGRST--VHAVKDVSFRIRRGT Mvan_3776|M.vanbaalenii_PYR-1 --PAVADAERLLEVDGLDVRFAVT--TPVGRST--VHAVRDVSFTVRRGT TH_4070|M.thermoresistible__bu --PQVTSTEVLLRVEGLQVRYDVS--TPTGRST--VRAVSDLSLSIRRGT MAB_0722|M.abscessus_ATCC_1997 -EPREDIGEPVLEVSHLVVEFPG----LLGRAA--FRAVDDVSFGIGRGK :: * : : * ** ::: : :. MSMEG_2844|M.smegmatis_MC2_155 TLALVGESGSGKSTTAKMIIGLTQPTRGSIEVLGH--DITRLGHRDRRAH MAV_3418|M.avium_104 TLALVGESGSGKSTTAKMVVGLLTPTRGTVRVLGR--DVAALPARARRRH Mb3687c|M.bovis_AF2122/97 TLAIVGESGSGKSTLARMVLGLLQPTSGTVVFDGT-YDVGALARDQVLAF Rv3663c|M.tuberculosis_H37Rv TLAIVGESGSGKSTLARMVLGLLQPTSGTVVFDGT-YDVGALARDQVLAF MMAR_5151|M.marinum_M TLAIVGESGSGKSTVARMVLGLLQPTSGTVSFDGARIQPDKLDRDAQLAF MUL_4237|M.ulcerans_Agy99 TLAIVGESGSGKSTVARMVLGLLQPTSGTVSFDGARIQPDKLDRDAQLAF MLBr_01122|M.leprae_Br4923 TLGIVGESGSGKSTTLHEILRLAVPQSGSIEVLGI--DVATLNRASRRSM Mflv_2758|M.gilvum_PYR-GCK TLGLVGESGSGKSTVAAALTGLVTPDAGTATLAGD--DVFSVKGRAARDM Mvan_3776|M.vanbaalenii_PYR-1 TLGLVGESGSGKSTVAACLTGLVKPDAGTANLAGV--DVLHVKGSAAKRI TH_4070|M.thermoresistible__bu TLGLVGESGSGKSTVAAALTGLVRPTAGRATLAGV--DLFGVRGRDRRRL MAB_0722|M.abscessus_ATCC_1997 TLGLVGESGSGKSTIGRCVAALQQPAAGSVRVLGQ--EIVGMSQRKLRPL **.:********** : * * * . * : : MSMEG_2844|M.smegmatis_MC2_155 WKNIQFVYQNPDSALDPRWSVREVLESPLRAYHLDN-RD---QRIAEALD MAV_3418|M.avium_104 WQDIQFVYQNPGSALDPRWTVRQILDGPLRSYRVDD-RARRAQRIAEALA Mb3687c|M.bovis_AF2122/97 RRRVQPVFQNPYSSLDPMYSVFRAIEEPLRVHHVGD-RRQRQRAVRELVD Rv3663c|M.tuberculosis_H37Rv RRRVQPVFQNPYSSLDPMYSVFRAIEEPLRVHHVGD-RRQRQRAVRELVD MMAR_5151|M.marinum_M RRRIQPVFQNPYSSLDPMYSVFRAIEEPLRIHRVGD-RAQRRQMVAELVD MUL_4237|M.ulcerans_Agy99 RCRIQPVFQNPYSSLDPMYSVFRAIEEPLRIHRVGD-RGQRRQMVAELVD MLBr_01122|M.leprae_Br4923 RRNIQVVFQDPVASLDPRLPVFELIAEPLHANGF-S-KNYTQMRVAELLD Mflv_2758|M.gilvum_PYR-GCK RRRIGLVFQDPFASLNPRARVDTSIAEPLVVHKVVDGKDARHRRVGELLD Mvan_3776|M.vanbaalenii_PYR-1 RRRVGLVFQDPFSSLNPRARVGDSVSEPLVVHKLVDGRETRRRRVEDLLD TH_4070|M.thermoresistible__bu RRRISLVFQDPFSSLNPRMRVIDSISEPLRVHGLADGDRARCRRVADLLE MAB_0722|M.abscessus_ATCC_1997 RAKFGFVFQDPATALNPKMRVGDCIAEPMWVHRYGD-RGKIVARVAELID . *:*:* ::*:* * : *: . : : : MSMEG_2844|M.smegmatis_MC2_155 NVNLSRDKLTRRTVELSGGERQRVAIARALVVQPQIILLDEPLSALDVVT MAV_3418|M.avium_104 SVGLSDDKLDRRPGELSGGECQRVAIARALVLRPQIVVLDEPLSALDVVT Mb3687c|M.bovis_AF2122/97 QVALPSSILGRRPRELSGGQRQRVAIARALALRPEVLVCDEAVSALDVLV Rv3663c|M.tuberculosis_H37Rv QVALPSSILGRRPRELSGGQRQRVAIARALALRPEVLVCDEAVSALDVLV MMAR_5151|M.marinum_M QVALPSSVLGRLPRELSGGQRQRVAIARALALRPDVLVCDEAVSALDVLV MUL_4237|M.ulcerans_Agy99 QVALPSSVLGRLPRELSGGQRQRVAIARALALRPDVLVCDEAVSALDVLV MLBr_01122|M.leprae_Br4923 IVGLRRDDATRYPTEFSGGQKQRIGIARALALQPKILAFDEPVSALDVSI Mflv_2758|M.gilvum_PYR-GCK LVGLPAEFAQRYPHELSGGQRQRVSIARALAAEPDLLILDEATASLDVSV Mvan_3776|M.vanbaalenii_PYR-1 LVGLPTEFADRYPHELSGGQRQRVSIARALAAEPDLLILDEATASLDVSA TH_4070|M.thermoresistible__bu LVGLPADFGARYPHELSGGQRQRVSVARALATDPDLLILDESTASLDVSV MAB_0722|M.abscessus_ATCC_1997 AVQLPSGTENRYPHELSGGQRQRANLARALALGPDLLVADEPTSALDVSV * * * . *:***: ** :****. *.:: **. ::*** MSMEG_2844|M.smegmatis_MC2_155 QDQILGLLRELQDNLGLTYLFISHDLSVVQQLSHRVVVLKAGQVAESGDT MAV_3418|M.avium_104 QDQIVGLLLRLQRQLGLTYLFVSHDLSVVRRLAHRVVVLRAGRVVETGDT Mb3687c|M.bovis_AF2122/97 QAQILDLLADLQADLGLTYLFISHDLAVIRQIADDVLVMRAGRVVEHAST Rv3663c|M.tuberculosis_H37Rv QAQILDLLADLQADLGLTYLFISHDLAVIRQIADDVLVMRAGRVVEHAST MMAR_5151|M.marinum_M QAQILDLLAELQADLGLAYLFISHDLAVVRQISDDVLVMRAGQVVEHAPT MUL_4237|M.ulcerans_Agy99 QAQILDLLAELQADLGLAYLFISHDLAVVRQISDDVLVMRAGQVVEHAPT MLBr_01122|M.leprae_Br4923 QAGIINLLLDLQDRLGLSYLFVSHDLSVIKHLAHQVAVMLAGTIVEQGDS Mflv_2758|M.gilvum_PYR-GCK QARVLELLSRLQSELALTYLLIGHDLAVIRQLSHDVLVMRDGEAVENRPA Mvan_3776|M.vanbaalenii_PYR-1 QARVLDLLSRLQRELGLTYLLIGHDLAVIRQVSHEILVMRGGQVVENRPA TH_4070|M.thermoresistible__bu QDRVLDLLADLQRELGLTYLFIAHDLAVVERMSHDVLVLRAGETVEYRPA MAB_0722|M.abscessus_ATCC_1997 QAAVLDLFEELQRQWRFACLFISHDLAVVDRLADEVAVLRHGVLEELGPR * :: *: ** :: *::.***:*: :::. : *: * * MSMEG_2844|M.smegmatis_MC2_155 AAVFSAPTSPYTRALIDAVPGR-RLARLALAS-- MAV_3418|M.avium_104 AAVFAAPAADYTRALLDAVPGR-RLAHPALSPS- Mb3687c|M.bovis_AF2122/97 EEVFSRPRHEYTRQLLQAIPGA-PSAPRKVGNL- Rv3663c|M.tuberculosis_H37Rv EEVFSRPRHEYTRQLLQAIPGA-PSAPRKVGNL- MMAR_5151|M.marinum_M EEVFTRPGAQYTQRLLEAIPGG-PVAPR------ MUL_4237|M.ulcerans_Agy99 EEVFTRPGAQYTQRLLEAIPGG-PVAPR------ MLBr_01122|M.leprae_Br4923 HDVFRNPQHDYTRRLLGAIPRP-EVG-------- Mflv_2758|M.gilvum_PYR-GCK DDLFAHPEQQYTRDLLAAVP---PRTPRAAV--- Mvan_3776|M.vanbaalenii_PYR-1 DELFTSPQQEYTRALLAAVP---PVKPRSAV--- TH_4070|M.thermoresistible__bu AELFAAPEHEYTRALLAAVP---AVRPRAAG--- MAB_0722|M.abscessus_ATCC_1997 GEILHNPSRAYTRALVAAVPVPDPVKQRARRNGH :: * **: *: *:*