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VITSVGEDAHRVDALLDLGRSERLADGAAQLAAEKPDAVMWACTSGSFVFGPEGAREQAAGVAAASGVPA SSTSLAFVDAAKHLGIRRVAVAASYPEDVAQHFVEFLRAGGIEVVTMGSHGIITAAEVGTLERDDVIAMV KAADHPEADAVLVPDTAMHTLAIIEDLETAVGKPVLTANQVTIWKGMELLGPVPVLPGLGTLFEGGRQ*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2490 | - | - | 100% (209) | decarboxylase |
| M. smegmatis MC2 155 | MSMEG_2495 | - | 5e-25 | 36.00% (175) | decarboxylase |
| M. smegmatis MC2 155 | MSMEG_3993 | - | 3e-13 | 25.77% (194) | Asp/Glu racemase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4412c | - | 1e-62 | 59.61% (203) | putative decarboxylase |
| M. marinum M | MMAR_3401 | - | 7e-17 | 31.69% (183) | maleate cis-trans isomerase |
| M. avium 104 | - | - | - | - | - |
| M. thermoresistible (build 8) | TH_4300 | - | 9e-05 | 31.54% (130) | PUTATIVE putative caib/baif family protein |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_2490|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4412c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_3401|M.marinum_M --------------------------------------------------
TH_4300|M.thermoresistible__bu MSSSAGTQAAPQSVTPLAGTRVVDLSTTLPGVVCTQFLADSGADVLMVEP
MSMEG_2490|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4412c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_3401|M.marinum_M --------------------------------------------------
TH_4300|M.thermoresistible__bu PGGSPVRSLRGWPAFGRGKRSTVVDLKSGSGADELDALLRDADVVVTTFS
MSMEG_2490|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4412c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_3401|M.marinum_M --------------------------------------------------
TH_4300|M.thermoresistible__bu PAALAELGIDSEALLARHPRLVIAHITGWGRSGPWRDLKGYEGLVLAKAG
MSMEG_2490|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4412c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_3401|M.marinum_M --------------------------------------------------
TH_4300|M.thermoresistible__bu LSHAVRRMANPPRPSYVTVPYASFAAGHIAVHGILAALHERDRSGLGQIV
MSMEG_2490|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4412c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_3401|M.marinum_M --------------------------------------------------
TH_4300|M.thermoresistible__bu DADLVRGVHSIDAWNWFGEMVGIRWPDAYENVEAWTEEGTPQSPMLLALL
MSMEG_2490|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4412c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_3401|M.marinum_M --------------------------------------------------
TH_4300|M.thermoresistible__bu AAPTKDGHWLQFAQVSPHLFAAMLTEFGMMELLADPKWKGFPALESPVLY
MSMEG_2490|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4412c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_3401|M.marinum_M --------------------------------------------------
TH_4300|M.thermoresistible__bu KEFWSIMLAKVGERTLAEWQQVFDNNPDLCAELFRSGPQVLDHPQLVHDR
MSMEG_2490|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4412c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_3401|M.marinum_M --------------------------------------------------
TH_4300|M.thermoresistible__bu RSTVVEDPEVGPVRQPSTLIHTADGPLRQPSPAPRLGEAGAGWRSEGVAM
MSMEG_2490|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4412c|M.abscessus_ATCC_199 ----------------------------------------------MTNI
MMAR_3401|M.marinum_M ----------------------------------------------MSSY
TH_4300|M.thermoresistible__bu AGGDASSQPPLAGITIVEFGEMFAAPYATSVLADLGARVIKFENVNGDNI
MSMEG_2490|M.smegmatis_MC2_155 -------------------------------MVITSVGEDAHRVDALLDL
MAB_4412c|M.abscessus_ATCC_199 RPTVGFIYPDHAAESDYPLVARQ---LDMNFPVVHIYGTDLHAVPELLDL
MMAR_3401|M.marinum_M RVGLLVPSSNTTMEAEVPEVLRANGSTTGDRFTFHASRMRMKKVDPQELM
TH_4300|M.thermoresistible__bu RNLLQFPEAAGAKVMQGKESIQVDLHTDEGKAVAHRIVASADVVLQSMRA
. . *
MSMEG_2490|M.smegmatis_MC2_155 GRSERLADGAAQLAAEKPDAVMWACTSGSFVFGP---EGAREQAAGVAA-
MAB_4412c|M.abscessus_ATCC_199 GSPERLAEGARLLRPHEPGAVVWACTSGSFVYGP---QGAAEQVAGLSE-
MMAR_3401|M.marinum_M AMNASAERATTELADAAVDVMAYACLVAVMAAGPNAHRTIEERLTKVAS-
TH_4300|M.thermoresistible__bu GAAERLGIDAATLRAVKP-DLIYVSAPGYGVDGPYGARPSYAPSIGAAGG
. : * : :.. . . ** . :
MSMEG_2490|M.smegmatis_MC2_155 ---------------------ASG--VPASSTSLAFVDAAKHLGIR----
MAB_4412c|M.abscessus_ATCC_199 ---------------------QSG--TPASSTSFAFVNAAVALGVS----
MMAR_3401|M.marinum_M ---------------------QSGGTVEVISSAGALVEGIRELGAK----
TH_4300|M.thermoresistible__bu VALTNTPDAACATSCLDEVMHQAPRVTSAGTAPELQSDGLAALAVASAIL
: . . ::. :. *.
MSMEG_2490|M.smegmatis_MC2_155 ---------------RVAVAASYPEDVAQHFVEFLRAGGIEVVTMGSHGI
MAB_4412c|M.abscessus_ATCC_199 ---------------KVAVAASYPRDIAELFVAFLAAHDIEVVSMGEAGI
MMAR_3401|M.marinum_M ---------------KIAMVAPYMKPLTSQVVDYIEAEGIEVMDVISLEV
TH_4300|M.thermoresistible__bu TALIGRDRGNPVNDVRTSMLGTVTHVLTDWLVDYPDAPTAPAPVHDGNGL
: :: .. . ::. .* : * . :
MSMEG_2490|M.smegmatis_MC2_155 ITAAEVGTLER-------------DDVIAMVKAADHPEADAVLVPD-TAM
MAB_4412c|M.abscessus_ATCC_199 DTAAEVGRLTA-------------HQVDELAGANDHPEAQALLIPD-TAM
MMAR_3401|M.marinum_M EDNRAVGRLDP-------------MRLPHIAHRLDTHDADAVVLSACVQM
TH_4300|M.thermoresistible__bu SALYRIYAAGDGHIFLAAPQPKEWQPLVDALRDFADLADDRFATPEGRAA
: : : . .
MSMEG_2490|M.smegmatis_MC2_155 HTLAIIEDLETAVGKP------------------VLTANQVTIWKGMELL
MAB_4412c|M.abscessus_ATCC_199 HTIAHVERLESRLDKV------------------VLTANQVTVWEGLRLI
MMAR_3401|M.marinum_M PSLAAIPAAEAMLGLP------------------VISAATATSWKILRSL
TH_4300|M.thermoresistible__bu NDDELARRLEAVFGKEPAAFWEKRLSAAGIGCVELYEGAPARLIQTDPAL
*: .. : . . : :
MSMEG_2490|M.smegmatis_MC2_155 GPVPVLPGLGTLFEGGRQ--------------------------------
MAB_4412c|M.abscessus_ATCC_199 DEVPDVSGLGRLFRRQHDDTGT----------------------------
MMAR_3401|M.marinum_M GVAPVAADAGALFDGGASG-------------------------------
TH_4300|M.thermoresistible__bu AAEYTVPAVSPVFDEHLRFSPLAGLSRSATRAPGGCLAGQHTAAVLREFG
. . :*
MSMEG_2490|M.smegmatis_MC2_155 ------------------
MAB_4412c|M.abscessus_ATCC_199 ------------------
MMAR_3401|M.marinum_M ------------------
TH_4300|M.thermoresistible__bu YDDATIAKWQDAGVINCG