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M. smegmatis MC2 155 MSMEG_2454 (-)

annotation: translation initiation inhibitor
coordinates: 2535043 - 2535504
length: 153

MSVRERLSALGIEIPPPAEPKGAYFPSRLVGDQLWISGTTSRRPTEPGAFGTVGEDVTPEQAQKHAGYAA
LNLIAAVDAAVGLEAVRGLVHLRGYVRASPHFDSHPAVIDGASRMLMDVFGEQRGAHARTAVGVASLPGG
ACVELELVASVRP
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_2454--100% (153)translation initiation inhibitor
M. smegmatis MC2 155MSMEG_6191-5e-2641.89% (148) translation initiation inhibitor
M. smegmatis MC2 155MSMEG_1464-4e-1438.81% (134) translation initiation inhibitor

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3702c-3e-2743.51% (154) hypothetical protein Mb3702c
M. gilvum PYR-GCKMflv_1369-5e-2643.84% (146) endoribonuclease L-PSP
M. tuberculosis H37RvRv3678c-3e-2743.51% (154) hypothetical protein Rv3678c
M. leprae Br4923MLBr_02304-2e-2744.16% (154) hypothetical protein MLBr_02304
M. abscessus ATCC 19977MAB_0413-2e-2744.90% (147) putative endoribonuclease
M. marinum MMMAR_5166-8e-2642.21% (154) hypothetical protein MMAR_5166
M. avium 104MAV_0451-8e-2740.67% (150) translation initiation inhibitor
M. thermoresistible (build 8)TH_2127-2e-2743.54% (147) CONSERVED HYPOTHETICAL PROTEIN
M. ulcerans Agy99MUL_4252-6e-2642.21% (154) hypothetical protein MUL_4252
M. vanbaalenii PYR-1Mvan_5437-5e-2744.22% (147) endoribonuclease L-PSP

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_1369|M.gilvum_PYR-GCK          -----------------MSSGWQ----ARLDELGIELPDVVAPLAAYVPA
Mvan_5437|M.vanbaalenii_PYR-1       ------------------MSGWS----ERLDELGIALPEVVAPLAAYVPA
MAB_0413|M.abscessus_ATCC_1997      ------------------MSTHS----ARLAELGIELPAVAAPLAAYQPA
TH_2127|M.thermoresistible__bu      ------------------VSTWS----NRLTELGISLPAVAAPVAAYVPA
Mb3702c|M.bovis_AF2122/97           ------------------MSAK-----ARLGQLGVTLPQVAAPLAAYVPA
Rv3678c|M.tuberculosis_H37Rv        ------------------MSAK-----ARLGQLGVTLPQVAAPLAAYVPA
MMAR_5166|M.marinum_M               ------------------MNAT-----SRLAELGITLPQVAAPLAAYVPA
MUL_4252|M.ulcerans_Agy99           ------------------MNAT-----SRLAELGITLPQVAAPLAAYVPA
MAV_0451|M.avium_104                ------------------MSAAPS-WKARLAELGLTLPEVVAPLASYVPA
MLBr_02304|M.leprae_Br4923          MGVSGGAARPHGRAACCILEASEMSVLARLGQLGIELPQAAPPLASYVSA
MSMEG_2454|M.smegmatis_MC2_155      ------------------MSVR-----ERLSALGIEIPPPAEPKGAYFPS
                                                       .        **  **: :*  . * .:* .:

Mflv_1369|M.gilvum_PYR-GCK          VRTGNLVYTSGQLPIRDGELLAAGKVGAEVSAEDAKPLARQCALNALAAV
Mvan_5437|M.vanbaalenii_PYR-1       VRTGNLVYTAGQLPISNGELAATGKVGAEVSAEDAKHLARRCALNALAAV
MAB_0413|M.abscessus_ATCC_1997      VRSGNHVYTSGQLPMVDGNLATAGKVGAEVSPEDAKALARICALNAVAAV
TH_2127|M.thermoresistible__bu      VRTGNLVYTSGQLPMVDGNLAATGKVGGEVTPEQAKALARVCALNALAAV
Mb3702c|M.bovis_AF2122/97           VRTGNLVYTAGQLPLEAGKLVRTGKLGADVNPEEGKTLARICALNALAAV
Rv3678c|M.tuberculosis_H37Rv        VRTGNLVYTAGQLPLEAGKLVRTGKLGADVNPEEGKTLARICALNALAAV
MMAR_5166|M.marinum_M               VRTGNLIYTAGQLPLEAGKLLGTGKVGANVTPEEGKALARVCALNALAAV
MUL_4252|M.ulcerans_Agy99           VRTGNLIYTAGQLPLEAGKLLGTGKVGANVTPEEGKALARVCALNALAAV
MAV_0451|M.avium_104                VRTGNLVYTAGQLPMQDGKLATTGKVGAHITPDEGRALARICALNALAAV
MLBr_02304|M.leprae_Br4923          VRTGNLVYTSGQLPIEDGRLPQTGKVGADVSLGEGKALARICALNALAAV
MSMEG_2454|M.smegmatis_MC2_155      RLVGDQLWISGTTSRRPTEPGAFGTVGEDVTPEQAQKHAGYAALNLIAAV
                                       *: :: :*  .    .    *.:* .:.  :.:  *  .*** :***

Mflv_1369|M.gilvum_PYR-GCK          HALTGIESVVKVVKVVGFVASAPGFDGQPGVINGASELFGEIFGE-AGAH
Mvan_5437|M.vanbaalenii_PYR-1       DALVGIDSVVKVVKVVGFVASAPGFDGQPGVINGASELFGEVFGE-AGAH
MAB_0413|M.abscessus_ATCC_1997      DALVGINNVVKVVKVVGFVASAPGFTGQPGVVNGASELLGEIFGE-AGVH
TH_2127|M.thermoresistible__bu      HDLAGIDAVTRIVKVVGFVASAPGFTGQPGVVNGASELFGEIFGD-AGAH
Mb3702c|M.bovis_AF2122/97           DSLVDLDAVTRVVKVVGFVASAPGFHGQPSVINGASDLLAEVFGD-SGAH
Rv3678c|M.tuberculosis_H37Rv        DSLVDLDAVTRVVKVVGFVASAPGFHGQPSVINGASDLLAEVFGD-SGAH
MMAR_5166|M.marinum_M               NSLVDIDSVTRVVKVVGFVASAPGFHGQPNVINGASDLLAEVFGD-KGVH
MUL_4252|M.ulcerans_Agy99           NSLVDIDSVTRVVKVVGFVASAPGFHGQPNVINGASDLLAEVFGD-KGVH
MAV_0451|M.avium_104                DALVGIDAVTRVVKVVGFVASAPGFNGQPSVVNGASDLLAEVFGE-HGAH
MLBr_02304|M.leprae_Br4923          DSLVGLDSVTGVVKVVGFVASSSGFNGQPSVVNGASDLFAEVFGD-RGRH
MSMEG_2454|M.smegmatis_MC2_155      DAAVGLEAVRGLVHLRGYVRASPHFDSHPAVIDGASRMLMDVFGEQRGAH
                                    .  ..:: *  :*:: *:* ::. * .:* *::*** :: ::**:  * *

Mflv_1369|M.gilvum_PYR-GCK          ARSAVGVSELPRNTPVEVEAIFEVA-----
Mvan_5437|M.vanbaalenii_PYR-1       ARSAVGVSELPRNAPVEVEVIVEVS-----
MAB_0413|M.abscessus_ATCC_1997      ARSAVGVAELPINAPVEVEIVVEVREEVSA
TH_2127|M.thermoresistible__bu      ARSAVGVSELPLDAPVEVELIAEIR-----
Mb3702c|M.bovis_AF2122/97           ARSAVGVSELPLDAPVEVELIVEVG-----
Rv3678c|M.tuberculosis_H37Rv        ARSAVGVSELPLDAPVEVELIVEVG-----
MMAR_5166|M.marinum_M               ARSAVGVAELPLDAPVEVELIVEVG-----
MUL_4252|M.ulcerans_Agy99           ARSAVGVAELPLDAPVEVELIVEVG-----
MAV_0451|M.avium_104                ARSAVGVGELPLDAPVEVELIVEVGARP--
MLBr_02304|M.leprae_Br4923          ARSAVGVAELPLGAPVEIELIVELG-----
MSMEG_2454|M.smegmatis_MC2_155      ARTAVGVASLPGGACVELELVASVRP----
                                    **:****..** .: **:* : .: