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M. smegmatis MC2 155 MSMEG_2339 (-)

annotation: IS1096, tnpA protein
coordinates: 2419579 - 2420901
length: 440

PDATGRAGFACADLTTFCRLDELGLEVTGQRLDPDRAVLACRVADEDRWCRRCGEEGVVRDSVTRTLAHE
PFGWRPTALLVTIRRYRCAGCAHVWRQDASAAAEPRARLSRRALRWALEALVCQHLSVARVAEALAVSWN
TANNAVLAEGQRVLIADPARFDGVAVIGVDEHVWRHTRRGDKYVTVIIDLTPVRDGTGPARLLDMVEGRS
KKAFADWLAQRPQEWRDRVDVVAMDGFSGFKTAATEELPDAATVMDPFHVVRLAGNALDECRRRVQLATC
GHRGRSTDPLYRSRRTLHTGADLLTDRQKARLAALFAANAHAEIEATWAMYQRTVAAYREPDRTKGRTMM
AALITTLSTGVPTSLTELITLGRTLKKRAADVLAYFDRPGTSNGPTEAINGRLEHLRGSALGFRNLTNYI
ARSLLETGGFRTQLRQPRR*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_2339--100% (440)IS1096, tnpA protein
M. smegmatis MC2 155MSMEG_6697-0.0100.00% (440) IS1096, tnpA protein
M. smegmatis MC2 155MSMEG_6462-0.0100.00% (440) IS1096, tnpA protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3382c-1e-0937.00% (100) transposase
M. gilvum PYR-GCKMflv_0315-4e-1724.58% (419) transposase, IS204/IS1001/IS1096/IS1165 family protein
M. tuberculosis H37RvRv2810c-3e-1859.30% (86) transposase
M. leprae Br4923-----
M. abscessus ATCC 19977-----
M. marinum MMMAR_1440-1e-15683.65% (318) ISL3 family transposase
M. avium 104-----
M. thermoresistible (build 8)TH_0237-3e-8255.41% (296) PROBABLE TRANSPOSASE
M. ulcerans Agy99-----
M. vanbaalenii PYR-1-----

CLUSTAL 2.0.9 multiple sequence alignment


MSMEG_2339|M.smegmatis_MC2_155      ---------------MPDATGRAGFACADLTTFCRLDELGLEVTGQRLDP
MMAR_1440|M.marinum_M               ---------------MPDAT----FACPDLTTFCRLDELGLEATGQHLAT
Rv2810c|M.tuberculosis_H37Rv        --------------------------------------------------
TH_0237|M.thermoresistible__bu      --------------------------------------------------
Mflv_0315|M.gilvum_PYR-GCK          MKDAHVVEPLGFGVTTPTSTARTTHVRVSTAFNRLLAIPGASVTDVVIGE
Mb3382c|M.bovis_AF2122/97           --------------------------------------------------
                                                                                      

MSMEG_2339|M.smegmatis_MC2_155      DRAVLACRVADEDRWCRRCGEEGVVRDSVTRTLAHEPFGWRPTALLVTIR
MMAR_1440|M.marinum_M               DRAVLACRITDDGSWCRRCGEQGTVRDGVTRQLAHEPFGWRPTTLLVTIR
Rv2810c|M.tuberculosis_H37Rv        --------------------------------------------------
TH_0237|M.thermoresistible__bu      --------------------------------------------------
Mflv_0315|M.gilvum_PYR-GCK          RDVEVTLRPTARLLTCPCGKRQPSVYDRRRRRWRHLDLGVKRLWLVNEIR
Mb3382c|M.bovis_AF2122/97           --------------------------------------------------
                                                                                      

MSMEG_2339|M.smegmatis_MC2_155      RYRCAGCAHVWRQDASAAAEPRARLSRRALRWALEALVCQHLSVARVAEA
MMAR_1440|M.marinum_M               RYRCQGCAHVWRQDSGKAAEPRAKLSRRGLRWALEAIVCRHLSVARIAEA
Rv2810c|M.tuberculosis_H37Rv        --------------------------------------------------
TH_0237|M.thermoresistible__bu      --------------------------------------------------
Mflv_0315|M.gilvum_PYR-GCK          RLNCPDCG------VITEAVPWARPGSRFTRDFEDMVLWLAQRSDRTTVS
Mb3382c|M.bovis_AF2122/97           ----------------------------------------------MAID
                                                                                      

MSMEG_2339|M.smegmatis_MC2_155      LAVSWNTANNAVLAEGQRVLIADPARFDGVAVIGVDEHVWRHTRRGDK--
MMAR_1440|M.marinum_M               LAVSWNTANNAVLAEGRRVLIADPARFDSVAVIGVDEHVWRHTRRGDK--
Rv2810c|M.tuberculosis_H37Rv        --------------------------------------------------
TH_0237|M.thermoresistible__bu      -------VNTVAAELTRELVFNSAGHLDGVRYLGVDEHKWKHRRGQGEAD
Mflv_0315|M.gilvum_PYR-GCK          TLMRCAWESVTAIINRGVAELLDKRRLQTLYRIGVDEICYRHP-------
Mb3382c|M.bovis_AF2122/97           PAAAYASAIRTPGLLPNAKLVVDHFHVTTLANDALTAVRRRVT-------
                                                                                      

MSMEG_2339|M.smegmatis_MC2_155      YVTVIIDLTPVRDGTGPARLLDMVEGRSKKAFADWLAQRPQEWRDRVDVV
MMAR_1440|M.marinum_M               YVIVIIDLTPVRDKTGPARLLDMVEGRSKKAFQDWLAGRPKQWRDGVEVV
Rv2810c|M.tuberculosis_H37Rv        ----------------PLRLQAHTGGPPVALRQETTGGPSP---------
TH_0237|M.thermoresistible__bu      FVTVIVDLTPVIDGTGPARLLDMVAGRSAAVLTDWLGAKDPNFRSRVKVM
Mflv_0315|M.gilvum_PYR-GCK          -----HRYLTIIGDHATGTVVNIRPGRSEQSLTDFYTAQPDSMLKQIQAV
Mb3382c|M.bovis_AF2122/97           -----WAFHDRRGRKIDPQWANRR--RLLTARERLSDKSFAKMRNRINAV
                                                                                      

MSMEG_2339|M.smegmatis_MC2_155      AMDGFSGFKTAATEELPDAATVMDPFHVVRLAGNALDECRRRVQLATCGH
MMAR_1440|M.marinum_M               AMDGFSGFKTATTEELPGAATVMAPFHVVRLAGNALDECRRRVQMDTCGH
Rv2810c|M.tuberculosis_H37Rv        -----------TNDLITEP-------------------PRHYKQQTR---
TH_0237|M.thermoresistible__bu      AMDGFAGYHTATADALPAARAVMDPFHVVHLAADKLTLCRQRVQQNTCGH
Mflv_0315|M.gilvum_PYR-GCK          SMDVSKPYIGATRSKVPEAIICFDGFHIMRWINRALDAVFSEAAAGPDKV
Mb3382c|M.bovis_AF2122/97           DPRAQILSAWIAKEELRTLLSTVRTGGDPHLARHHLHRFLPGASTRRSPN
                                               : . :                                  

MSMEG_2339|M.smegmatis_MC2_155      RGRSTDPLYRSRRTLHTGADLLTDRQK---------ARLAALFAANAHA-
MMAR_1440|M.marinum_M               RGRRTDPLYACRRTLQTGADLLTDKQK---------TRLTALLSCAVG--
Rv2810c|M.tuberculosis_H37Rv        -----------------------------------VRQAPALLTVSAG--
TH_0237|M.thermoresistible__bu      RGRSGDPLFGIRRILLTRTELLTPRQKAKLDKALSAHDAHAAVEVTACYY
Mflv_0315|M.gilvum_PYR-GCK          HMSSAQWRTTRWALRTGENRLTDTKRELVNQIAKQNRRVGRAWALKEQAR
Mb3382c|M.bovis_AF2122/97           CSPWPPPLTSHPRSTPSWSPASPTRAS-------VVGEVAEMLGDIDG--
                                                                                      

MSMEG_2339|M.smegmatis_MC2_155      ------------------------EIEATWAMYQRTVAAYREPDRTKGRT
MMAR_1440|M.marinum_M               -----------------------------------FVLRLNSADPGAGFA
Rv2810c|M.tuberculosis_H37Rv        ---------------------------TGVPVVLEELAKLGRTLWRCRHD
TH_0237|M.thermoresistible__bu      QDLIGAYANPDRRAGKLAMFKCLKRIRSGLPKGLDELAQLGRSLWKRRHE
Mflv_0315|M.gilvum_PYR-GCK          DLYRYDHQPG------VARALLKAWITAAKRCRIPAFVALGKRLAVYFDG
Mb3382c|M.bovis_AF2122/97           -----------------------------------QCVQVEVPVPERGPA
                                                                                      

MSMEG_2339|M.smegmatis_MC2_155      MMAALITTLSTGVPTSLTELITLGRTLKKRAADVLAYFDRPGTSNGPTEA
MMAR_1440|M.marinum_M               MLLAACVAISR-------------------------------------FA
Rv2810c|M.tuberculosis_H37Rv        VLAYFDHHASNG----------------------------------PTEA
TH_0237|M.thermoresistible__bu      ILAYFDVGVSNG----------------------------------PVEA
Mflv_0315|M.gilvum_PYR-GCK          ILAAIELGISNA----------------------------------LAES
Mb3382c|M.bovis_AF2122/97           GCGGLDGLGRAG-----------------------------------VSA
                                                                                     :

MSMEG_2339|M.smegmatis_MC2_155      INGRLEHLRGSALGFRNLTNYIARSLLETGGFRTQLRQPRR
MMAR_1440|M.marinum_M               CDGCHSVAFGSAWTDDLLPGWW-------------------
Rv2810c|M.tuberculosis_H37Rv        INGRLEALCRNALGFRNLTHYRIRSLLHCGNLAQLIHAL--
TH_0237|M.thermoresistible__bu      INGRLEHLRGIALGFRNLNHYILRSLIHSGQLQNRINAL--
Mflv_0315|M.gilvum_PYR-GCK          INAKIRLINARGYGHHTAETLTSMIYLCLGGLQVKLPTRT-
Mb3382c|M.bovis_AF2122/97           TPRVCAAMTAVNVAGRCAGQQADVGPTPQHRCRGR------