For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MTTTFEAQIIADETVAPRAPWSKIVRAGDVLTIVDLHGNQAVDTLFYGADDHGIRYSAPATIAAQGNIFL TTGTVLRDSDGAPMLTIIDDEVGNHDTLGGACSQESNTLRYGHHTKHQHACVENFIGEGARWGLTKADIV SNINFFMNVPVDPDGSLGIVDGLSAPGKKLSLRAEIDTLVLISNCPQINNPCNGFDPTAVRMVVTRG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2186 | - | - | 100% (207) | hypothetical protein MSMEG_2186 |
| M. smegmatis MC2 155 | MSMEG_2968 | - | 2e-14 | 28.90% (173) | hypothetical protein MSMEG_2968 |
| M. smegmatis MC2 155 | MSMEG_2185 | - | 8e-13 | 26.53% (196) | hypothetical protein MSMEG_2185 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_5134 | - | 8e-13 | 27.80% (205) | aminomethyltransferase |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4092 | - | 4e-91 | 78.46% (195) | hypothetical protein MAB_4092 |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | - | - | - | - | - |
| M. thermoresistible (build 8) | TH_0713 | - | 1e-80 | 70.71% (198) | conserved hypothetical protein |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_1202 | - | 1e-11 | 28.88% (187) | glycine cleavage T protein (aminomethyl transferase) |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_2186|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4092|M.abscessus_ATCC_1997 --------------------------------------------------
TH_0713|M.thermoresistible__bu --------------------------------------------------
Mflv_5134|M.gilvum_PYR-GCK MAPGSVTAVPVFGGDRFDIVDQYGRQPAELTVLAADPRAVADAPPDTAAT
Mvan_1202|M.vanbaalenii_PYR-1 -----MTAVRVFGGDRLDVVDHYGRQPAELTVLATDPRAVVGTRPDAPAT
MSMEG_2186|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4092|M.abscessus_ATCC_1997 --------------------------------------------------
TH_0713|M.thermoresistible__bu --------------------------------------------------
Mflv_5134|M.gilvum_PYR-GCK VLRSLIPGSDENGYAAQRILSLLARHRVDQQEAVATRLFGHHSPAGSRAT
Mvan_1202|M.vanbaalenii_PYR-1 VLRHLIPGPDENGYAAARILSLLSDHHVHQQDSTATRLFDGPSPAGARVS
MSMEG_2186|M.smegmatis_MC2_155 ----------------------------------------------MTTT
MAB_4092|M.abscessus_ATCC_1997 ----------------------------------------MDRRADGKDA
TH_0713|M.thermoresistible__bu ----------------------------------------------VEPL
Mflv_5134|M.gilvum_PYR-GCK FTVDADAVVLVAAPASPMHPHSDDPNPPSEVRVAVYRADPGRPATPELPP
Mvan_1202|M.vanbaalenii_PYR-1 FAVDADAVVLVAAPAAAMDLTGPEPNPPSEVRVEVHRADPRRPQVRELPA
MSMEG_2186|M.smegmatis_MC2_155 FEAQIIADETVAPRAPWSKIVRAGDVLTIVDLHGNQAVDTLFYGA-----
MAB_4092|M.abscessus_ATCC_1997 VKDSTILDEVVPARAPWSTVVAAGDVLTIIDLKGNQAVDTLLYSA-----
TH_0713|M.thermoresistible__bu VLGTVILDETVPARAPWSAVVAAGDVLTIVDLAGNQAVDCLLYSA-----
Mflv_5134|M.gilvum_PYR-GCK PLAEPLLDLRIDAETAASYEVREGQFIQIIDVAGRQCSDFLAFDARGLAD
Mvan_1202|M.vanbaalenii_PYR-1 PLAEPLWETRVDAATASSYEVGAGQFIQIIDVAGQQCSDFLAFDARALGD
: : : . :. * * *:.: *:*: *.*. * * :.*
MSMEG_2186|M.smegmatis_MC2_155 -DDHGIRYSAPATIAAQGNIFLTTGTVLRDSDGAPMLTIIDDEVGNHDTL
MAB_4092|M.abscessus_ATCC_1997 -ADTGVRYSAQATIAAQSNLFLRAGTVLRAEDGSPLMTIVEDEVGSHDTI
TH_0713|M.thermoresistible__bu -ADTSVRYSAPETIRRQGRITLTTGSVLRADTGDALMTVVADEVGAHDTL
Mflv_5134|M.gilvum_PYR-GCK GREYGLDATTTRTIGGAAYPRPGLRGKFYDARARPLVEVVRDTVGRHDTF
Mvan_1202|M.vanbaalenii_PYR-1 GAEFGLDATTTRTIGGGAYPRPGLFGKFFDSRARPLVEVVRDTVGRHDTF
: .: :: ** . : . .:: :: * ** ***:
MSMEG_2186|M.smegmatis_MC2_155 GGACSQES-NTLRYGHHTKHQHACVENFIGEGARWGLTKADIVSNINFFM
MAB_4092|M.abscessus_ATCC_1997 GGACSQES-NTLRYGHHTKHQHACVENFLLEGAKWGLGKRDLVSNINFYM
TH_0713|M.thermoresistible__bu GGACSKES-NTLRYGPHTGAQHGCMENFLLEGSRWGLGARDLASNINWFM
Mflv_5134|M.gilvum_PYR-GCK ALACTAKYYADLGYLGHVN----CTDNFNGALARFGVDRRQGWPALNLFY
Mvan_1202|M.vanbaalenii_PYR-1 ALACTAKYYADLGYPGHVN----CTDNFNATLSRFGVQPRRGWPALNLFY
. **: : * * *. * :** :::*: . :* :
MSMEG_2186|M.smegmatis_MC2_155 NVPVDPDGSLGIVDGLSAPGKKLSLRAEIDTLVLISNCPQINNPCNGFDP
MAB_4092|M.abscessus_ATCC_1997 NVPVDDDGTLGIVDGLSAPGKKIKLRAEVDTLVLVSNCPQINNPCNGFDP
TH_0713|M.thermoresistible__bu NVPVDPDGALGIVDGLSAPGKRVAVRAETDTLVLVSNCPQINNPCNAFHP
Mflv_5134|M.gilvum_PYR-GCK NTAFDAAHQLISDEPWSCAGDYVLFRASADLVCASSACPDDIDPANGWVP
Mvan_1202|M.vanbaalenii_PYR-1 NTAFDAQHQLVSDEPWSRPGDYVLLRACSDLVCASSACPDDIDAANGWLP
*...* * : * .*. : .** * : * **: :..*.: *
MSMEG_2186|M.smegmatis_MC2_155 TAVRMVVTRG----------------------------------------
MAB_4092|M.abscessus_ATCC_1997 TPVRMVVESL----------------------------------------
TH_0713|M.thermoresistible__bu TPVRMIVTRPEGSV------------------------------------
Mflv_5134|M.gilvum_PYR-GCK TDIHVRVYDSSRRFSVAVGHRLTPDSEPVLTKSTAFARRTGALTTDFTEY
Mvan_1202|M.vanbaalenii_PYR-1 TDIHVRVYDSTRRFSVAVGHRLTPDSEPVLTKPTAFANRTGALTSNFTEY
* ::: *
MSMEG_2186|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4092|M.abscessus_ATCC_1997 --------------------------------------------------
TH_0713|M.thermoresistible__bu --------------------------------------------------
Mflv_5134|M.gilvum_PYR-GCK NGYWLPNRYANHGPHDEYWACREHVAVMDLSALRKFEVLGPDAEALLQAT
Mvan_1202|M.vanbaalenii_PYR-1 KGYWLPNSFDNHGPHQEYWACRERVAVMDLSALRKFEVLGPDAEELLQAT
MSMEG_2186|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4092|M.abscessus_ATCC_1997 --------------------------------------------------
TH_0713|M.thermoresistible__bu --------------------------------------------------
Mflv_5134|M.gilvum_PYR-GCK LTRDIRRLSRGQVVYSAMCSESGGVVDDCTVLRLGDNNFRFIGGDPHGGV
Mvan_1202|M.vanbaalenii_PYR-1 LTRDVRRLSRGQVVYSAMCTEAGGVVDDCTVLRLGDNNFRFIGGDPYDGI
MSMEG_2186|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4092|M.abscessus_ATCC_1997 --------------------------------------------------
TH_0713|M.thermoresistible__bu --------------------------------------------------
Mflv_5134|M.gilvum_PYR-GCK WLRTQAERLGLHQVWIKDSTDQMHNLAVQGPASRAVLDGLIWTPPGQPAL
Mvan_1202|M.vanbaalenii_PYR-1 WLRTQAERLGLGQVWIKDSSDHMHNLAVQGPSSRELLCELIWSPPGQPAL
MSMEG_2186|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4092|M.abscessus_ATCC_1997 --------------------------------------------------
TH_0713|M.thermoresistible__bu --------------------------------------------------
Mflv_5134|M.gilvum_PYR-GCK RDLGWFRFLTGRLDGPDGAPLLVSRTGYTGELGYEVWVHPGDAETLWDRL
Mvan_1202|M.vanbaalenii_PYR-1 RDLGWFRFLIGRLDGPEGPPLLVSRTGYTGELGYELWIHPNDAETLWDRV
MSMEG_2186|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4092|M.abscessus_ATCC_1997 --------------------------------------------------
TH_0713|M.thermoresistible__bu --------------------------------------------------
Mflv_5134|M.gilvum_PYR-GCK WDAGRPHGLTPLGLEALEMVRIEAGLAAGGHEFDDQTDPFEAGIGFTVPL
Mvan_1202|M.vanbaalenii_PYR-1 WEAGQAYGLAPLGLEALELLRVESGLVAAGHEFDEQTDPFEAGIGFTVPL
MSMEG_2186|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4092|M.abscessus_ATCC_1997 --------------------------------------------------
TH_0713|M.thermoresistible__bu --------------------------------------------------
Mflv_5134|M.gilvum_PYR-GCK KTKTDDFVGRAALVERKAHPQRTLVGLRLDSNETTAHGDCVHLGRTQVGV
Mvan_1202|M.vanbaalenii_PYR-1 KSKSDDFVGRDALIERKAHPQRALVGLRLDGNEVAAHGDCVHIGRSQVGV
MSMEG_2186|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4092|M.abscessus_ATCC_1997 --------------------------------------------------
TH_0713|M.thermoresistible__bu --------------------------------------------------
Mflv_5134|M.gilvum_PYR-GCK VTSATRSPLLGASIALCRIAVQHSEPGTRVEIGKLDGHLKRIPATVTTIP
Mvan_1202|M.vanbaalenii_PYR-1 VTSGIRSPVLGAGIALCRIAVQYTAPGTRVEVGKLDGHRKRLAATVTTVP
MSMEG_2186|M.smegmatis_MC2_155 -----------
MAB_4092|M.abscessus_ATCC_1997 -----------
TH_0713|M.thermoresistible__bu -----------
Mflv_5134|M.gilvum_PYR-GCK FYDSDKTRPRS
Mvan_1202|M.vanbaalenii_PYR-1 FYDPDKIRPRS