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M. smegmatis MC2 155 MSMEG_2060 (nuoD)

annotation: NADH dehydrogenase subunit D
coordinates: 2140228 - 2141556
length: 442

STSTVPPDGGEKVVVVGGNDWHEVVAAARAGAAAQAGERIVVNMGPQHPSTHGVLRLILEIEGEIITEAR
CGIGYLHTGIEKNLEYRNWTQGVTFVTRMDYLSPFFNETAYCLGVEKLLGITDDIPERASVIRVMLMELN
RISSHLVALATGGMELGAMSAMFYGFREREEILRVFESITGLRMNHAYIRPGGLAADLPDDAITQVRRLV
EILPKRLKDLEDLLNENYIWKARTVGVGYLDLTGCMALGITGPILRSTGLPHDLRKAQPYCGYENYEFDV
ITDDRCDSYGRYIIRVKEMHESVKIVEQCLARLKPGPVMISDKKLAWPADLKLGPDGLGNSPEHIAKIMG
RSMEGLIHHFKLVTEGIRVPPGQVYVAVESPRGELGVHMVSDGGTRPYRVHYRDPSFTNLQAVAATCEGG
MVADAIAAVASIDPVMGGVDR*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_2060nuoD-100% (442)NADH dehydrogenase subunit D

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3172nuoD0.081.94% (432) NADH dehydrogenase subunit D
M. gilvum PYR-GCKMflv_4484-0.083.48% (454) NADH dehydrogenase subunit D
M. tuberculosis H37RvRv3148nuoD0.081.94% (432) NADH dehydrogenase subunit D
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_2137-0.082.71% (428) NADH dehydrogenase subunit D
M. marinum MMMAR_1480nuoD0.082.83% (431) NADH dehydrogenase I (chain D) NuoD (NADH- ubiquinone
M. avium 104MAV_4036nuoD0.080.86% (444) NADH dehydrogenase subunit D
M. thermoresistible (build 8)TH_0634nuoD0.086.08% (431) PROBABLE NADH DEHYDROGENASE I (CHAIN D) NUOD
M. ulcerans Agy99MUL_2462nuoD0.082.60% (431) NADH dehydrogenase subunit D
M. vanbaalenii PYR-1Mvan_1882-0.086.74% (445) NADH dehydrogenase subunit D

CLUSTAL 2.0.9 multiple sequence alignment


MSMEG_2060|M.smegmatis_MC2_155      MSTSTVPPD--GGEKVVVVGGNDWHEVVAAARAG---------AAAQAGE
TH_0634|M.thermoresistible__bu      --MSTRP------ETVITLGGQDWDQLVAEARSN---------AADQTGE
Mflv_4484|M.gilvum_PYR-GCK          MTTSAQRP-----ERVIVVGGQDWDQVVTAARQMSNSSSRAGDAAEHAGE
Mvan_1882|M.vanbaalenii_PYR-1       MTTSQQPP-----ERVVVVGGQDWDQVVAAARQN---------AAEHAGE
MAB_2137|M.abscessus_ATCC_1997      --MTAQP------EIHLMAGGQDWDEIVTAAGQA-------------TDE
Mb3172|M.bovis_AF2122/97            MTAIADSAG-GAGETVLVAGGQDWQQVVDAARSAD------------PGE
Rv3148|M.tuberculosis_H37Rv         MTAIADSAG-GAGETVLVAGGQDWQQVVDAARSAD------------PGE
MAV_4036|M.avium_104                MSTTTESTHDGAGETLVVAGGQDWDKVVEAARSAD------------PGE
MMAR_1480|M.marinum_M               MTDT---------ETVLVAGGQDWNEIVEAARGAD------------PGE
MUL_2462|M.ulcerans_Agy99           MTDT---------ETVLVAGGQDWNEIVEAARGAD------------PGE
                                                 *  :  **:**.::*  *                ..*

MSMEG_2060|M.smegmatis_MC2_155      RIVVNMGPQHPSTHGVLRLILEIEGEIITEARCGIGYLHTGIEKNLEYRN
TH_0634|M.thermoresistible__bu      RIVVNMGPQHPSTHGVLRLVLEIEGETVTEARCGVGYLHTGIEKNLEYRT
Mflv_4484|M.gilvum_PYR-GCK          RIVVNMGPQHPSTHGVLRLILEIEGETIVEARCGIGYLHTGIEKNLEFRT
Mvan_1882|M.vanbaalenii_PYR-1       RIVVNMGPQHPSTHGVLRLILEIEGEIIVEARCGIGYLHTGIEKNLEFRN
MAB_2137|M.abscessus_ATCC_1997      RIVVNMGPQHPSTHGVLRLILEIEGETVTDVRCGIGYLHTGIEKNLEYRT
Mb3172|M.bovis_AF2122/97            RIVVNMGPQHPSTHGVLRLILEIEGETVVEARCGIGYLHTGIEKNLEYRY
Rv3148|M.tuberculosis_H37Rv         RIVVNMGPQHPSTHGVLRLILEIEGETVVEARCGIGYLHTGIEKNLEYRY
MAV_4036|M.avium_104                RIVVNMGPQHPSTHGVLRLILEIEGETVTEARCGIGYLHTGIEKNLEYRY
MMAR_1480|M.marinum_M               RIVVNMGPQHPSTHGVLRLILEIEGETVTEARCGIGYLHTGIEKNLEYRY
MUL_2462|M.ulcerans_Agy99           RIVVNMGPQHPSTHGVLRLILEIEGETVTEARCGIGYLHTGIEKNLEYRY
                                    *******************:****** :.:.***:************:* 

MSMEG_2060|M.smegmatis_MC2_155      WTQGVTFVTRMDYLSPFFNETAYCLGVEKLLGITDDIPERASVIRVMLME
TH_0634|M.thermoresistible__bu      WMQGVTFVTRMDYLSPFFNETVYCLGVEKLLGITEAIPERANVIRVMLME
Mflv_4484|M.gilvum_PYR-GCK          WTQGVTFVTRMDYLSPFFNETAYCLGVEKLLGVTDDIPERASVIRVMMME
Mvan_1882|M.vanbaalenii_PYR-1       WTQGVTFVTRMDYLSPFFNETAYCLGVEKLLGITDAIPERASVIRVMMME
MAB_2137|M.abscessus_ATCC_1997      WTQGVTFVTRMDYLSPFFNETAYCLGVEQLLGIADEIPERANVIRVLMME
Mb3172|M.bovis_AF2122/97            WTQGVTFVTRMDYLSPFFNETAYCLGVEKLLGITDEIPERVNVIRVLMME
Rv3148|M.tuberculosis_H37Rv         WTQGVTFVTRMDYLSPFFNETAYCLGVEKLLGITDEIPERVNVIRVLMME
MAV_4036|M.avium_104                WTQGVTFVTRMDYLSPFFNETAYCLGVEKLLGITDQIPERVNVIRVMMME
MMAR_1480|M.marinum_M               WTQGVTFVTRMDYLSPFFNETAYCLGVEKLLGITDEIPERVNVIRVMMME
MUL_2462|M.ulcerans_Agy99           WTQGVTFVTRMDYLSPFFNETAYCLGVEKLLGITDEIPERVNVIRVMMME
                                    * *******************.******:***::: ****..****::**

MSMEG_2060|M.smegmatis_MC2_155      LNRISSHLVALATGGMELGAMSAMFYGFREREEILRVFESITGLRMNHAY
TH_0634|M.thermoresistible__bu      LNRISSHLVALATGGMELGAMTAMFLGFREREEILKVFELITGLRMNHAY
Mflv_4484|M.gilvum_PYR-GCK          LNRISSHLVALATGGMELGAMTAMFLGFRERELILSVFETITGLRMNSAY
Mvan_1882|M.vanbaalenii_PYR-1       LNRISSHLVALATGGMELGAMTAMFLGFRERELILSVFETITGLRMNNAY
MAB_2137|M.abscessus_ATCC_1997      LNRISSHLVALATGGMELGAMTAMFLGFREREMILKVFEAITGLRMNHAY
Mb3172|M.bovis_AF2122/97            LNRISSHLVALATGGMELGAMTPMFVGFRAREIVLTLFEKITGLRMNSAY
Rv3148|M.tuberculosis_H37Rv         LNRISSHLVALATGGMELGAMTPMFVGFRAREIVLTLFEKITGLRMNSAY
MAV_4036|M.avium_104                LNRISSHLVALATGGMELGAMTPMFVGFRGREIVLTLFESITGLRMNSAY
MMAR_1480|M.marinum_M               LNRISSHLVALATGGMELGAMTPMFVGFRAREIILSLFESITGLRMNSAY
MUL_2462|M.ulcerans_Agy99           LNRISSHLVALAAGGMELGAMTPMFVGFRAREIILSLFESITGLRMNSAY
                                    ************:********:.** *** ** :* :** ******* **

MSMEG_2060|M.smegmatis_MC2_155      IRPGGLAADLPDDAITQVRRLVEILPKRLKDLEDLLNENYIWKARTVGVG
TH_0634|M.thermoresistible__bu      IRPGGLAADLPPDAVPRVRELLELLPGRLRDLEDLLSQNHIWRARNEGVG
Mflv_4484|M.gilvum_PYR-GCK          IRPGGVAADLPEEGLPQIRELLTLLPTRLRDMENLLNENYIWKARTLGVG
Mvan_1882|M.vanbaalenii_PYR-1       IRPGGVAADLPDEALPQVRDLLTLLPKRLRDMEDLLNENYIWKARTQGIG
MAB_2137|M.abscessus_ATCC_1997      VRPGGLAQDLPDGAEQEVRDLLEILPGRLRDMENLLNENYIWKARTQGVG
Mb3172|M.bovis_AF2122/97            IRPGGVAQDLPPNAATEIAEALKQLRQPLREMGELLNENAIWKARTQGVG
Rv3148|M.tuberculosis_H37Rv         IRPGGVAQDLPPNAATEIAEALKQLRQPLREMGELLNENAIWKARTQGVG
MAV_4036|M.avium_104                IRPGGVAQDLPPNAKTEIAQALDQLRQPLREMGDLLNENAIWKARTQDIG
MMAR_1480|M.marinum_M               IRPGGVAQDLPPDGPTEIAKAIADLRQPLREMGDLLNENAIWKARTQDVG
MUL_2462|M.ulcerans_Agy99           IRPGGVAQDLPPDRPTEIAKAIADLRQPLREMGDLLNENAIWKARTQDVG
                                    :****:* ***     .:   :  *   *::: :**.:* **:**. .:*

MSMEG_2060|M.smegmatis_MC2_155      YLDLTGCMALGITGPILRSTGLPHDLRKAQPYCGYENYEFDVITDDRCDS
TH_0634|M.thermoresistible__bu      YLDLTGCMALGVTGPVLRSAGLPHDLRKSQPYCGYENYEFDVITDDRCDA
Mflv_4484|M.gilvum_PYR-GCK          YLDLTGCMALGITGPVLRSTGLPHDLRKSQPYCGYQTYDFDVITDDRCDS
Mvan_1882|M.vanbaalenii_PYR-1       YLDLTGCMALGITGPVLRSTGLPHDLRKAQPYCGYETYDFDVVTDDQCDS
MAB_2137|M.abscessus_ATCC_1997      YLDLTGCMALGITGPVLRATGLAHDLRRAQPYCGYENYDFDVVTHQDCDS
Mb3172|M.bovis_AF2122/97            YLDLTGCMALGITGPILRSTGLPHDLRKSEPYCGYQHYEFDVITDDSCDA
Rv3148|M.tuberculosis_H37Rv         YLDLTGCMALGITGPILRSTGLPHDLRKSEPYCGYQHYEFDVITDDSCDA
MAV_4036|M.avium_104                YLDLTGCMALGITGPILRATGLPHDLRKSEPYCGYENYEFDVITADTCDA
MMAR_1480|M.marinum_M               YLDLAGCMALGITGPILRSTGLPHDLRKSEPYCGYENYEFDVITADGCDA
MUL_2462|M.ulcerans_Agy99           YLDLAGCMALGITGPILRSTGLPHDLRKSEPYCGYENYEFDVITADGCDA
                                    ****:******:***:**::**.****:::*****: *:***:* : **:

MSMEG_2060|M.smegmatis_MC2_155      YGRYIIRVKEMHESVKIVEQCLARLKP---GPVMISDKKLAWPADLKLGP
TH_0634|M.thermoresistible__bu      YGRFMIRVKEMHESLKIVEQCLDRLRP---GPVMIEDRKLAWPADLKLGP
Mflv_4484|M.gilvum_PYR-GCK          YGRYLIRVKEMRESLRIVEQCVERLERSTGEPVMITDRKLAWPADLKVGP
Mvan_1882|M.vanbaalenii_PYR-1       YGRYLIRVKEMHQSIRIVEQCVQRLERSVGAPVMITDKKLAWPADLKVGP
MAB_2137|M.abscessus_ATCC_1997      YGRYLIRVKEMHESIKIAQQCVDRLRP---GPVMVDDKKIAWPADLASGP
Mb3172|M.bovis_AF2122/97            YGRYMIRVKEMWESMKIVEQCLDKLRP---GPTMISDRKLAWPADLQVGP
Rv3148|M.tuberculosis_H37Rv         YGRYMIRVKEMWESMKIVEQCLDKLRP---GPTMISDRKLAWPADLQVGP
MAV_4036|M.avium_104                YGRYMIRVKEMWESIKIVEQCLDKLQP---GPIMVENGKIAWPADLKVGP
MMAR_1480|M.marinum_M               YGRYMIRVKEMWESIKIVEQCLDRLRP---GPTMIEDRKLAWPADLKVGP
MUL_2462|M.ulcerans_Agy99           YGRYMIRVKEMWESIKIVEQCLDRLRP---GPTMIEDRKLAWPADLKVGP
                                    ***::****** :*::*.:**: :*.     * *: : *:******  **

MSMEG_2060|M.smegmatis_MC2_155      DGLGNSPEHIAKIMGRSMEGLIHHFKLVTEGIRVPPGQVYVAVESPRGEL
TH_0634|M.thermoresistible__bu      DGLGNSPEHVARIMGRSMEGLIHHFKLVTEGIRVPPGQVYVAVESPRGEL
Mflv_4484|M.gilvum_PYR-GCK          DGLGNSPEHIAKIMGHSMEGLIHHFKLVTEGIRVPPGQVYVAVESPRGEL
Mvan_1882|M.vanbaalenii_PYR-1       DGLGNSPEHIAKIMGHSMEGLIHHFKLVTEGIRVPAGQVYVAVESPRGEL
MAB_2137|M.abscessus_ATCC_1997      DGLGNSPKHIAKIMGTSMEGLIHHFKLVTEGVRVPAGQVYVAIESPRGEL
Mb3172|M.bovis_AF2122/97            DGLGNSPKHIAKIMGSSMEALIHHFKLVTEGIRVPAGQVYVAVESPRGEL
Rv3148|M.tuberculosis_H37Rv         DGLGNSPKHIAKIMGSSMEALIHHFKLVTEGIRVPAGQVYVAVESPRGEL
MAV_4036|M.avium_104                DGLGNSPEHIAKIMGGSMEALIHHFKLVTEGIRVPPGQVYTAVESPRGEL
MMAR_1480|M.marinum_M               DGMGNSPEHIAKIMGSSMEALIHHFKLVTEGIRVPAGQVYVAVESPRGEL
MUL_2462|M.ulcerans_Agy99           DGMGNSPEHIAKIMGSSMEALIHHFKLVTEGIRVPAGQVYVAVESPRGEL
                                    **:****:*:*:*** ***.***********:***.****.*:*******

MSMEG_2060|M.smegmatis_MC2_155      GVHMVSDGGTRPYRVHYRDPSFTNLQAVAATCEGGMVADAIAAVASIDPV
TH_0634|M.thermoresistible__bu      GVHMVSDGGTRPYRVHYRDPSFTNLQAVAAMAEGGMVADLIAALASIDPV
Mflv_4484|M.gilvum_PYR-GCK          GVHMVSDGGTRPYRVHYRDPSFTNLQAVAAMCEGGMVADAITAVASIDPV
Mvan_1882|M.vanbaalenii_PYR-1       GVHMVSDGGTRPYRVHYRDPSFTNLQAVAAMCEGGMVADAITAVASIDPV
MAB_2137|M.abscessus_ATCC_1997      GVHMVSDGGTRPYRVHFRDPSFTNLQSVAAMCEGAMVADLIAAVASIDPV
Mb3172|M.bovis_AF2122/97            GVHMVSDGGTRPYRVHYRDPSFTNLQSVAAMCEGGMVADLIAAVASIDPV
Rv3148|M.tuberculosis_H37Rv         GVHMVSDGGTRPYRVHYRDPSFTNLQSVAAMCEGGMVADLIAAVASIDPV
MAV_4036|M.avium_104                GVHMVSDGGTRPYRVHYRDPSFTNLQSVAAMCEGGMVADLITAVASIDPV
MMAR_1480|M.marinum_M               GVHMVSDGGTRPYRVHYRDPSFTNLQAVAAMSEGGMVADLITAVASIDPV
MUL_2462|M.ulcerans_Agy99           GVHMVSDGGTRPYRVHYRDPSFTNLQAVAAMSEGGMVADLITAVASIDPV
                                    ****************:*********:*** .**.**** *:*:******

MSMEG_2060|M.smegmatis_MC2_155      MGGVDR
TH_0634|M.thermoresistible__bu      MGGVDR
Mflv_4484|M.gilvum_PYR-GCK          MGGVDR
Mvan_1882|M.vanbaalenii_PYR-1       MGGVDR
MAB_2137|M.abscessus_ATCC_1997      MGGVDR
Mb3172|M.bovis_AF2122/97            MGGVDR
Rv3148|M.tuberculosis_H37Rv         MGGVDR
MAV_4036|M.avium_104                MGGVDR
MMAR_1480|M.marinum_M               MGGVDR
MUL_2462|M.ulcerans_Agy99           MGGVDR
                                    ******