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M. smegmatis MC2 155 MSMEG_1850 (selA)

TDPRRRVPRTDTLLADPRLAAAEQVLGRALVRSVIAEAQQKARAGEIPPEQVADAAVAALPTGATSLRPV
INATGVVVHTNLGRAPLSRAAIDAVVTASGATDVEFDLETGRRARRGRGALAALARAVPTAGGVHVVNNN
AAALLLAAMTLAPGKEMIVSRGELIEIGDGFRLPALMESTGSRIREVGTTNRTHLRDYADAVGPDTGFVL
KVHPSNYSVSGFTSSVPVRELAALDAPLVVDIGSGLLTPHPLLPDEPDATTMLRDGADLVTASGDKLLGG
PQAGLLFGTEDLIERLRRHPAARALRVDKLTLAALEATLTGPPPPVAQALSVDVESLRVRAGRLASLLPD
AKAVDCTAAVGGGGAPDVELPSAAVSLPEAYAAPLRVGNPSVVGRLENGRCLLDLRTVAPEDDGKLVEAV
RACSS*

Operon Prediction Model: Genebank

Paralogs

species	id	gene	e-value	identity (len)	annotation
M. smegmatis MC2 155	MSMEG_1850	selA	-	100% (426)	selenocysteine synthase

Closest Orthologs (e-value cutoff: 1e-4)

species	id	gene	e-value	identity (len)	annotation
M. bovis AF2122 / 97	-	-	-	-	-
M. gilvum PYR-GCK	-	-	-	-	-
M. tuberculosis H37Rv	-	-	-	-	-
M. leprae Br4923	-	-	-	-	-
M. abscessus ATCC 19977	MAB_2746c	-	2e-05	25.53% (333)	cysteine desulfurase/aminotransferase
M. marinum M	MMAR_5190	selA	0.0	78.55% (429)	selenocysteine synthase, SelA
M. avium 104	MAV_0418	selA	0.0	80.05% (426)	selenocysteine synthase
M. thermoresistible (build 8)	-	-	-	-	-
M. ulcerans Agy99	-	-	-	-	-
M. vanbaalenii PYR-1	-	-	-	-	-

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_5190|M.marinum_M               MGDGSDRRRAVPRTDVLLAHPKLAEAQRTLGRTLVKSVIAQAQQRARAGE
MAV_0418|M.avium_104                ----------MPGTDTLLADPRLAAAQRVLGRALVKSVITQAQQRARAGE
MSMEG_1850|M.smegmatis_MC2_155      ---MTDPRRRVPRTDTLLADPRLAAAEQVLGRALVRSVIAEAQQKARAGE
MAB_2746c|M.abscessus_ATCC_199      -----------------------MTATVPLDITAIRNDFPILSRTVRGGK
                                                             *   *. : ::. :.  .: .*.*:

MMAR_5190|M.marinum_M               IEPDQVAEHAIDALPGTASSLRPVINATGVVVHTNLGRAPLSRAALDAVV
MAV_0418|M.avium_104                ISPEQVAEHALAALPATASSLRPVINATGVVVHTNLGRAPLSRAALDAVV
MSMEG_1850|M.smegmatis_MC2_155      IPPEQVADAAVAALPTGATSLRPVINATGVVVHTNLGRAPLSRAAIDAVV
MAB_2746c|M.abscessus_ATCC_199      PLAYLDSGATSQRPVQVLDAERRFLTERNAAVHR--GAHQLAEEATDAYE
                                      .   :  :         : * .:.  ...**   *   *:. * **  

MMAR_5190|M.marinum_M               TAGRATDVEFDLATGRRARRGRSALAALARAVPSAAGVHVVNNNAAALLL
MAV_0418|M.avium_104                AAGGATDVEFDLATGRRARRGRGALAALARAVPAAGGVHVVNNNAAALLL
MSMEG_1850|M.smegmatis_MC2_155      TASGATDVEFDLETGRRARRGRGALAALARAVPTAGGVHVVNNNAAALLL
MAB_2746c|M.abscessus_ATCC_199      GARNAIARFVGVDDGE-IVFTKNATESLNLVAYTLGDNRFDR--------
                                     *  *    ..:  *.     :.*  :*  .. : .. :. .        

MMAR_5190|M.marinum_M               TALTLAAPGKEIVLSRGELVEIGDGFRIPELLASTGSRLREVGTTNRTSL
MAV_0418|M.avium_104                VALTLAP-GREIVLSRGELVEIGDGFRIPELLESTGARLREVGTTNRTGL
MSMEG_1850|M.smegmatis_MC2_155      AAMTLAP-GKEMIVSRGELIEIGDGFRLPALMESTGSRIREVGTTNRTHL
MAB_2746c|M.abscessus_ATCC_199      ---AVGP-GDEIVVT--ELEHHANLVPWQELCRRTGATLRWFGVTDDGRI
                                       ::.. * *::::  ** . .: .    *   **: :* .*.*:   :

MMAR_5190|M.marinum_M               RDYAEAIGPNTGFVLKVHPSNFHVTGFTSAVGVS----ELAQLDAPLVVD
MAV_0418|M.avium_104                RDYTEALGPQTGFVLKVHPSNFHVTGFTSAVGVAALAAELRTRDIPLVVD
MSMEG_1850|M.smegmatis_MC2_155      RDYADAVGPDTGFVLKVHPSNYSVSGFTSSVPVR----ELAALDAPLVVD
MAB_2746c|M.abscessus_ATCC_199      DVDSLELTEAVKVVAFTHQSNVTGAVAPVAELVR------RAKAVGALVV
                                       :  :   . .*  .* **   :  . :  *              :* 

MMAR_5190|M.marinum_M               IGSGLLAPHPLLPDEPDATTMLRDGANLVTASGDKLLGGPQAGLLFGDAD
MAV_0418|M.avium_104                IGSGLLAPHPVLPDEPDATSTLADGADLVTASGDKLLGGPQAGLLFGRGD
MSMEG_1850|M.smegmatis_MC2_155      IGSGLLTPHPLLPDEPDATTMLRDGADLVTASGDKLLGGPQAGLLFGTED
MAB_2746c|M.abscessus_ATCC_199      LDACQSVPHMSVN-------FRELGVDYAAFSGHKMLGPSGVGVLYGRRA
                                    :.:   .**  :            *.: .: **.*:** . .*:*:*   

MMAR_5190|M.marinum_M               LIERLR----RHPAARALRVDKLTLAALEATVVG--PPTPVAQALGADLT
MAV_0418|M.avium_104                LVERLR----RHPAARALRVDKLTLAALEATLTG--PPPPVAAALDADVG
MSMEG_1850|M.smegmatis_MC2_155      LIERLR----RHPAARALRVDKLTLAALEATLTG--PPPPVAQALSVDVE
MAB_2746c|M.abscessus_ATCC_199      LLEAMPPFITGGSMIETVTMEVSTYAPPPQRFEAGVPMTSQVVGLGAAVD
                                    *:* :       .  .:: ::  * *.    . .  * .. . .*.. : 

MMAR_5190|M.marinum_M               ELRARAQRITAQLPQSVGATAVDCIAAVG------------GGGAPGVEL
MAV_0418|M.avium_104                RLRARAQSLAAALPADADAVALDCVAAVG------------GGGAPGVEL
MSMEG_1850|M.smegmatis_MC2_155      SLRVRAGRLASLLP---DAKAVDCTAAVG------------GGGAPDVEL
MAB_2746c|M.abscessus_ATCC_199      YLNAVGMEAVAAHEHQLVSAALAGLAGIEGVRIIGPTDNLDRGGAVSFVV
                                     *.. .   .:       : *:   *.:              *** .. :

MMAR_5190|M.marinum_M               PSAGLS----LPESYAATLRTGS------PPVVGRLEAGRCLLDLRTVAP
MAV_0418|M.avium_104                PSAAVS----LPERYAAALRAGR------PPVVGRLEGGRCLLDLRTVSP
MSMEG_1850|M.smegmatis_MC2_155      PSAAVS----LPEAYAAPLRVGN------PSVVGRLENGRCLLDLRTVAP
MAB_2746c|M.abscessus_ATCC_199      DGIHAHDLGQVLDDEGVAVRVGHHCAWPLHRRFGIAASARASFAVYNTLD
                                     .        : :  ...:*.*          .*    .*. : : ..  

MMAR_5190|M.marinum_M               EEDELLLAAVRACLS--
MAV_0418|M.avium_104                EDDELLAAAVRACSS--
MSMEG_1850|M.smegmatis_MC2_155      EDDGKLVEAVRACSS--
MAB_2746c|M.abscessus_ATCC_199      EVDRLTAGVRRAQEFFS
                                    * *     . **