For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. smegmatis MC2 155 MSMEG_1659 (-)

annotation: multidrug resistance protein, SMR family protein
coordinates: 1754723 - 1755040
length: 105

AWLILVVSGVMEAVWASALSKSEAFTRLWPSVIFLISAPVSLVGLAVAMRTLPPGTSYSVWVGIGASLTV
GYAMLTGAESTSLIKILLILGVVGCVIGLKVVSH*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_1659--100% (105)multidrug resistance protein, SMR family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3092mmr2e-0730.30% (99) multidrugs-transport integral membrane protein MMR
M. gilvum PYR-GCKMflv_5270-7e-2853.85% (104) small multidrug resistance protein
M. tuberculosis H37RvRv3065mmr2e-0730.30% (99) multidrugs-transport integral membrane protein MMR
M. leprae Br4923MLBr_01756-2e-0630.30% (99) putative multidrug resistance protein
M. abscessus ATCC 19977MAB_2640c-3e-1939.42% (104) putative multidrug resistance protein
M. marinum MMMAR_2872-2e-2956.86% (102) multidrug-transport integral membrane protein Mmr-like protein
M. avium 104MAV_4309-3e-3462.14% (103) multidrug resistance protein, SMR family protein
M. thermoresistible (build 8)TH_4220-4e-0930.00% (100) PUTATIVE -
M. ulcerans Agy99MUL_2881-1e-2956.86% (102) multidrugs-transport integral membrane protein Mmr-like
M. vanbaalenii PYR-1Mvan_0339-1e-0828.30% (106) small multidrug resistance protein

CLUSTAL 2.0.9 multiple sequence alignment


MSMEG_1659|M.smegmatis_MC2_155      ----------------MAWLILVVSGVMEAVWASALSKSEAFTRLWPSVI
MAV_4309|M.avium_104                ----------------MAWLILIASGVLEAVWATALSRSEGFSRLGPSLV
MMAR_2872|M.marinum_M               ----------------MSWIVLVMSGVLEAVWATALGRSEGFSKPAPSVV
MUL_2881|M.ulcerans_Agy99           MGAVPGVRQDGPGRNAVSWIVLVMSGVLEAVWATALGRSEGFSKPAPSVV
TH_4220|M.thermoresistible__bu      ----------------MAWLILIVSGAFEAVFTVSPSRTEGFTRPIPIIV
Mflv_5270|M.gilvum_PYR-GCK          ----------------MAWLILVASGFLEAVWATALGMSNGFRRRRPTVV
MAB_2640c|M.abscessus_ATCC_199      ----------------MVWLVLVLAGLLEVGWAIGLKYTEGFTRLWPTVG
Mb3092|M.bovis_AF2122/97            ----------------MIYLYLLCAIFAEVVATSLLKSTEGFTRLWPTVG
Rv3065|M.tuberculosis_H37Rv         ----------------MIYLYLLCAIFAEVVATSLLKSTEGFTRLWPTVG
MLBr_01756|M.leprae_Br4923          ----------------MAYLFLFCAIFVEVVATTLLKSTEGFTRLVPTLA
Mvan_0339|M.vanbaalenii_PYR-1       -------------MPGVAWTLLGGAILAEVIATSMLKSTEGFTRLWPTLA
                                                    : :  *  :   *.  :     ::.* :  * : 

MSMEG_1659|M.smegmatis_MC2_155      FLISAPVSLVGLAVAMRT-LPPGTSYSVWVGIGASLTVGYAMLTGAESTS
MAV_4309|M.avium_104                FFVALAFSMTGLAVAMRS-LPVGTSYAVWVGVGAALTVTYAALVGDEPAS
MMAR_2872|M.marinum_M               FLVAFIVSMAGLAYAMRD-LSVGTAYAVWVGIGAVLTVVYAMATGDEPAS
MUL_2881|M.ulcerans_Agy99           FLVAFIVSMAGLAYAMRD-LSVGTAYAVWVGIGAVLTVVYAMATGDEPAS
TH_4220|M.thermoresistible__bu      FLVAVIISMG---------------------------------------A
Mflv_5270|M.gilvum_PYR-GCK          FAVAMPASLAGLAYAMTE-VPTGTAYAVWVGIGATLTVVWAIVTKKEAAT
MAB_2640c|M.abscessus_ATCC_199      TVGSMIISIALLGIAMKS-LPVGTAYAIWVGVGAVGTAILGIVLFGDSAN
Mb3092|M.bovis_AF2122/97            CLVGYGIAFALLALSISHGMQTDVAYALWSAIGTAAIVLVAVLFLGSPIS
Rv3065|M.tuberculosis_H37Rv         CLVGYGIAFALLALSISHGMQTDVAYALWSAIGTAAIVLVAVLFLGSPIS
MLBr_01756|M.leprae_Br4923          CLAGYAVTFTLLALSISRGMKTDVAYALWSAIGTAAIVLIAVLFLDSPVS
Mvan_0339|M.vanbaalenii_PYR-1       CLLLYGAAFMLLAQSISHGMQVGIAYALWSAIGTTVIVAVGVTFLGEPIS
                                           ::                                         

MSMEG_1659|M.smegmatis_MC2_155      LIKILLILGVVGCVIGLKVVSH--
MAV_4309|M.avium_104                PVKLVLIAGIVACVAGLKLLG---
MMAR_2872|M.marinum_M               LLKVAFLAMIIGSVIGLKLAH---
MUL_2881|M.ulcerans_Agy99           LLKVAFLAMIIGSVIGLKLAH---
TH_4220|M.thermoresistible__bu      LLKVALLLGLIGCIVGLNPDQ---
Mflv_5270|M.gilvum_PYR-GCK          TARVLLLCLLVGSVVGLKAVS---
MAB_2640c|M.abscessus_ATCC_199      VWRLLSLGLIVAGIIGLKLAT---
Mb3092|M.bovis_AF2122/97            VMKVVGVGLIVVGVVTLNLAGAH-
Rv3065|M.tuberculosis_H37Rv         VMKVVGVGLIVVGVVTLNLAGAH-
MLBr_01756|M.leprae_Br4923          VAKVVGVALIIVGVITLNLADAH-
Mvan_0339|M.vanbaalenii_PYR-1       TLKVIGVALVVSGVVTLQLDGHQA
                                      ::  :  ::  :  *: